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Items: 1 to 50 of 209

1.

Escmid-ecmm guideline: diagnosis and management of invasive aspergillosis in neonates and children.

Warris A, Lehrnbecher T, Roilides E, Castagnola E, Bruggemann RJM, Groll AH.

Clin Microbiol Infect. 2019 May 31. pii: S1198-743X(19)30282-4. doi: 10.1016/j.cmi.2019.05.019. [Epub ahead of print]

PMID:
31158517
2.

The clinical management of invasive mold infection in children with cancer or undergoing hematopoietic stem cell transplantation.

Lehrnbecher T.

Expert Rev Anti Infect Ther. 2019 Jun 8:1-11. doi: 10.1080/14787210.2019.1626718. [Epub ahead of print]

PMID:
31149864
3.

Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia-A prospective international multicenter trial on behalf of the BFM-SG and the EBMT-PDWP.

Pichler H, Lawitschka A, Glogova E, Willasch AM, von Luettichau I, Lehrnbecher T, Matthes-Martin S, Lang P, Bader P, Sykora KW, Schrum J, Kremens B, Ehlert K, Albert MH, Kuhlen M, Meisel R, Guengoer T, Strahm B, Gruhn B, Schulz A, Woessmann W, Poetschger U, Peters C.

Am J Hematol. 2019 May 16. doi: 10.1002/ajh.25511. [Epub ahead of print]

PMID:
31095771
4.

Extended Dosing Regimens for Fungal Prophylaxis.

Lehrnbecher T, Bochennek K, Klingebiel T, Gastine S, Hempel G, Groll AH.

Clin Microbiol Rev. 2019 May 15;32(3). pii: e00010-19. doi: 10.1128/CMR.00010-19. Print 2019 Jun 19. Review.

PMID:
31092507
5.

Invasive mold disease of the central nervous system in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation: Analysis of 29 contemporary patients.

Lauten M, Attarbaschi A, Cario G, Döring M, Moser O, Mücke U, Poyer F, Rieken S, Temme C, Voigt S, Lehrnbecher T, Groll AH.

Pediatr Blood Cancer. 2019 May 7:e27806. doi: 10.1002/pbc.27806. [Epub ahead of print]

PMID:
31066209
6.

Incidence and Outcome of Invasive Fungal Diseases in Children With Hematological Malignancies and/or Allogeneic Hematopoietic Stem Cell Transplantation: Results of a Prospective Multicenter Study.

Lehrnbecher T, Schöning S, Poyer F, Georg J, Becker A, Gordon K, Attarbaschi A, Groll AH.

Front Microbiol. 2019 Apr 16;10:681. doi: 10.3389/fmicb.2019.00681. eCollection 2019.

7.

A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia.

Arrieta AC, Sung L, Bradley JS, Zwaan CM, Gates D, Waskin H, Carmelitano P, Groll AH, Lehrnbecher T, Mangin E, Joshi A, Kartsonis NA, Walsh TJ, Paschke A.

PLoS One. 2019 Mar 26;14(3):e0212837. doi: 10.1371/journal.pone.0212837. eCollection 2019.

8.

Why are natural killer cells important for defense against Aspergillus?

Lehrnbecher T, Schmidt S.

Med Mycol. 2019 Apr 1;57(Supplement_2):S206-S210. doi: 10.1093/mmy/myy034. Review.

PMID:
30816962
9.

Pontine tumor in a neonate: case report and analysis of the current literature.

Buus-Gehrig C, Lehrnbecher T, Porto L, Becker M, Freiman T, Mittelbronn M, Bochennek K.

J Neurosurg Pediatr. 2019 Feb 15:1-7. doi: 10.3171/2018.10.PEDS18215. [Epub ahead of print]

PMID:
30771760
10.

Vaccination of patients with haematological malignancies who did not have transplantations: guidelines from the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Mikulska M, Cesaro S, de Lavallade H, Di Blasi R, Einarsdottir S, Gallo G, Rieger C, Engelhard D, Lehrnbecher T, Ljungman P, Cordonnier C; European Conference on Infections in Leukaemia group.

Lancet Infect Dis. 2019 Jun;19(6):e188-e199. doi: 10.1016/S1473-3099(18)30601-7. Epub 2019 Feb 8. Review. Erratum in: Lancet Infect Dis. 2019 Apr;19(4):e109.

PMID:
30744964
11.

Vaccination of haemopoietic stem cell transplant recipients: guidelines of the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Cordonnier C, Einarsdottir S, Cesaro S, Di Blasi R, Mikulska M, Rieger C, de Lavallade H, Gallo G, Lehrnbecher T, Engelhard D, Ljungman P; European Conference on Infections in Leukaemia group.

Lancet Infect Dis. 2019 Jun;19(6):e200-e212. doi: 10.1016/S1473-3099(18)30600-5. Epub 2019 Feb 8. Review.

PMID:
30744963
12.

Revaccination in Children Undergoing Autologous Hematopoietic Stem Cell Transplantation: Results of a Survey in Germany, Austria and Switzerland.

Laws HJ, Simon A, Lehrnbecher T.

Klin Padiatr. 2019 May;231(3):136-141. doi: 10.1055/a-0796-6719. Epub 2019 Jan 2.

PMID:
30602176
13.

Longitudinal assessment of peripheral blood BRAFV600E levels in patients with Langerhans cell histiocytosis.

Schwentner R, Kolenová A, Jug G, Schnöller T, Ahlmann M, Meister B, Lehrnbecher T, Minkov M, Hutter C.

Pediatr Res. 2019 May;85(6):856-864. doi: 10.1038/s41390-018-0238-y. Epub 2018 Nov 24.

PMID:
30474648
14.

Treatment of fever in neutropenia in pediatric oncology patients.

Lehrnbecher T.

Curr Opin Pediatr. 2019 Feb;31(1):35-40. doi: 10.1097/MOP.0000000000000708.

PMID:
30461508
15.

Impact of Antifungal Compounds on Viability and Anti-Aspergillus Activity of Human Natural Killer Cells.

Schmidt S, Schubert R, Tramsen L, Lehrnbecher T.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01993-18. doi: 10.1128/AAC.01993-18. Print 2019 Feb.

PMID:
30455240
16.

Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients.

Diorio C, Robinson PD, Ammann RA, Castagnola E, Erickson K, Esbenshade A, Fisher BT, Haeusler GM, Kuczynski S, Lehrnbecher T, Phillips R, Cabral S, Dupuis LL, Sung L.

J Clin Oncol. 2018 Sep 14:JCO1800407. doi: 10.1200/JCO.18.00407. [Epub ahead of print]

17.

Vemurafenib in Langerhans cell histiocytosis: report of a pediatric patient and review of the literature.

Heisig A, Sörensen J, Zimmermann SY, Schöning S, Schwabe D, Kvasnicka HM, Schwentner R, Hutter C, Lehrnbecher T.

Oncotarget. 2018 Apr 24;9(31):22236-22240. doi: 10.18632/oncotarget.25277. eCollection 2018 Apr 24.

18.

Natural killer cells as a therapeutic tool for infectious diseases - current status and future perspectives.

Schmidt S, Tramsen L, Rais B, Ullrich E, Lehrnbecher T.

Oncotarget. 2018 Apr 17;9(29):20891-20907. doi: 10.18632/oncotarget.25058. eCollection 2018 Apr 17. Review.

19.

Diagnostic Approaches for Invasive Aspergillosis-Specific Considerations in the Pediatric Population.

Lehrnbecher T, Hassler A, Groll AH, Bochennek K.

Front Microbiol. 2018 Mar 26;9:518. doi: 10.3389/fmicb.2018.00518. eCollection 2018. Review.

20.

[Recommendations for Diagnostics and Therapy of Children with Cancer Presenting with Fever and Neutropenia - Comparison of Two Current Guidelines].

Lehrnbecher T, Groll A, Agyeman P, Ammann RA, Attarbaschi A, Behrends U, Berger C, Hamprecht A, Hufnagel M, Laws HJ, Scheler M, Temme C, Vieth S, Simon A.

Klin Padiatr. 2018 Apr;230(3):115-121. doi: 10.1055/s-0044-101953. Epub 2018 Mar 27. Review. German.

PMID:
29589346
21.

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012.

Rasche M, Zimmermann M, Borschel L, Bourquin JP, Dworzak M, Klingebiel T, Lehrnbecher T, Creutzig U, Klusmann JH, Reinhardt D.

Leukemia. 2018 Oct;32(10):2167-2177. doi: 10.1038/s41375-018-0071-7. Epub 2018 Feb 22.

22.

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline.

Ullmann AJ, Aguado JM, Arikan-Akdagli S, Denning DW, Groll AH, Lagrou K, Lass-Flörl C, Lewis RE, Munoz P, Verweij PE, Warris A, Ader F, Akova M, Arendrup MC, Barnes RA, Beigelman-Aubry C, Blot S, Bouza E, Brüggemann RJM, Buchheidt D, Cadranel J, Castagnola E, Chakrabarti A, Cuenca-Estrella M, Dimopoulos G, Fortun J, Gangneux JP, Garbino J, Heinz WJ, Herbrecht R, Heussel CP, Kibbler CC, Klimko N, Kullberg BJ, Lange C, Lehrnbecher T, Löffler J, Lortholary O, Maertens J, Marchetti O, Meis JF, Pagano L, Ribaud P, Richardson M, Roilides E, Ruhnke M, Sanguinetti M, Sheppard DC, Sinkó J, Skiada A, Vehreschild MJGT, Viscoli C, Cornely OA.

Clin Microbiol Infect. 2018 May;24 Suppl 1:e1-e38. doi: 10.1016/j.cmi.2018.01.002. Epub 2018 Mar 12.

23.

NK Cells and Their Role in Invasive Mold Infection.

Schmidt S, Condorelli A, Koltze A, Lehrnbecher T.

J Fungi (Basel). 2017 May 19;3(2). pii: E25. doi: 10.3390/jof3020025. Review.

24.

Crizotinib in ALK+ inflammatory myofibroblastic tumors-Current experience and future perspectives.

Theilen TM, Soerensen J, Bochennek K, Becker M, Schwabe D, Rolle U, Klingebiel T, Lehrnbecher T.

Pediatr Blood Cancer. 2018 Apr;65(4). doi: 10.1002/pbc.26920. Epub 2017 Dec 29. Review.

PMID:
29286567
25.

Impact of human mesenchymal stromal cells on antifungal host response against Aspergillus fumigatus.

Schmidt S, Tramsen L, Schneider A, Schubert R, Balan A, Degistirici Ö, Meisel R, Lehrnbecher T.

Oncotarget. 2017 Sep 8;8(56):95495-95503. doi: 10.18632/oncotarget.20753. eCollection 2017 Nov 10.

26.

Natural Killer Cells in Antifungal Immunity.

Schmidt S, Tramsen L, Lehrnbecher T.

Front Immunol. 2017 Nov 22;8:1623. doi: 10.3389/fimmu.2017.01623. eCollection 2017. Review.

27.

Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children.

Gastine S, Lehrnbecher T, Müller C, Farowski F, Bader P, Ullmann-Moskovits J, Cornely OA, Groll AH, Hempel G.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01194-17. doi: 10.1128/AAC.01194-17. Print 2018 Jan.

28.

Role of Molecular Biomarkers in the Diagnosis of Invasive Fungal Diseases in Children.

Huppler AR, Fisher BT, Lehrnbecher T, Walsh TJ, Steinbach WJ.

J Pediatric Infect Dis Soc. 2017 Sep 1;6(suppl_1):S32-S44. doi: 10.1093/jpids/pix054. Review.

29.

Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children.

King J, Pana ZD, Lehrnbecher T, Steinbach WJ, Warris A.

J Pediatric Infect Dis Soc. 2017 Sep 1;6(suppl_1):S12-S21. doi: 10.1093/jpids/pix053. Review.

30.

Progress in the Diagnosis of Invasive Fungal Disease in Children.

Warris A, Lehrnbecher T.

Curr Fungal Infect Rep. 2017;11(2):35-44. doi: 10.1007/s12281-017-0274-9. Epub 2017 May 2. Review.

31.

Risk Factors for Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review.

Fisher BT, Robinson PD, Lehrnbecher T, Steinbach WJ, Zaoutis TE, Phillips B, Sung L.

J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):191-198. doi: 10.1093/jpids/pix030. Review.

32.

Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update.

Lehrnbecher T, Robinson P, Fisher B, Alexander S, Ammann RA, Beauchemin M, Carlesse F, Groll AH, Haeusler GM, Santolaya M, Steinbach WJ, Castagnola E, Davis BL, Dupuis LL, Gaur AH, Tissing WJE, Zaoutis T, Phillips R, Sung L.

J Clin Oncol. 2017 Jun 20;35(18):2082-2094. doi: 10.1200/JCO.2016.71.7017. Epub 2017 May 1. Review.

PMID:
28459614
33.

Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.

Rasche M, von Neuhoff C, Dworzak M, Bourquin JP, Bradtke J, Göhring G, Escherich G, Fleischhack G, Graf N, Gruhn B, Haas OA, Klingebiel T, Kremens B, Lehrnbecher T, von Stackelberg A, Tchinda J, Zemanova Z, Thiede C, von Neuhoff N, Zimmermann M, Creutzig U, Reinhardt D.

Leukemia. 2017 Dec;31(12):2807-2814. doi: 10.1038/leu.2017.121. Epub 2017 Apr 25.

34.

The Non-Langerhans Cell Histiocytoses (Rare Histiocytoses) - Clinical Aspects and Therapeutic Approaches.

Classen CF, Minkov M, Lehrnbecher T.

Klin Padiatr. 2016 Nov;228(6-07):294-306. Epub 2016 Nov 15. Review.

PMID:
27846659
35.

Disseminated Fusariosis in Immunocompromised Children-Analysis of Recent Cases Identified in the Global Fungiscope Registry.

Hassler A, Lieb A, Seidel D, Cesaro S, Greil J, Klimko N, Khostelidi S, Solopova G, Ogunc D, Durán Graeff L, Cornely OA, Vehreschild MJ, Lehrnbecher T.

Pediatr Infect Dis J. 2017 Feb;36(2):230-231. doi: 10.1097/INF.0000000000001396.

PMID:
27846057
36.

Current Algorithms in Fungal Diagnosis in the Immunocompromised Host.

Lehrnbecher T, Becker K, Groll AH.

Methods Mol Biol. 2017;1508:67-84.

PMID:
27837498
37.

Role of natural killer cells in antibacterial immunity.

Schmidt S, Ullrich E, Bochennek K, Zimmermann SY, Lehrnbecher T.

Expert Rev Hematol. 2016 Dec;9(12):1119-1127. Epub 2016 Nov 11. Review.

PMID:
27791439
38.

Galactomannan, β-D-Glucan, and Polymerase Chain Reaction-Based Assays for the Diagnosis of Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.

Lehrnbecher T, Robinson PD, Fisher BT, Castagnola E, Groll AH, Steinbach WJ, Zaoutis TE, Negeri ZF, Beyene J, Phillips B, Sung L.

Clin Infect Dis. 2016 Nov 15;63(10):1340-1348. Epub 2016 Aug 27. Review.

39.

Aspergillus fumigatus responds to natural killer (NK) cells with upregulation of stress related genes and inhibits the immunoregulatory function of NK cells.

Schneider A, Blatzer M, Posch W, Schubert R, Lass-Flörl C, Schmidt S, Lehrnbecher T.

Oncotarget. 2016 Nov 1;7(44):71062-71071. doi: 10.18632/oncotarget.12616.

40.

Anti-ALK Antibodies in Patients with ALK-Positive Malignancies Not Expressing NPM-ALK.

Damm-Welk C, Siddiqi F, Fischer M, Hero B, Narayanan V, Camidge DR, Harris M, Burke A, Lehrnbecher T, Pulford K, Oschlies I, Siebert R, Turner S, Woessmann W.

J Cancer. 2016 Jun 30;7(11):1383-7. doi: 10.7150/jca.15238. eCollection 2016.

41.

Risk stratification in febrile neutropenic episodes in adolescent/young adult patients with cancer.

Phillips RS, Bhuller K, Sung L, Ammann RA, Tissing WJ, Lehrnbecher T, Stewart LA; PICNICC Collaboration.

Eur J Cancer. 2016 Sep;64:101-6. doi: 10.1016/j.ejca.2016.05.027. Epub 2016 Jul 5.

42.

Lack of Effectiveness of Neutropenic Diet and Social Restrictions as Anti-Infective Measures in Children With Acute Myeloid Leukemia: An Analysis of the AML-BFM 2004 Trial.

Tramsen L, Salzmann-Manrique E, Bochennek K, Klingebiel T, Reinhardt D, Creutzig U, Sung L, Lehrnbecher T.

J Clin Oncol. 2016 Aug 10;34(23):2776-83. doi: 10.1200/JCO.2016.66.7881. Epub 2016 Jun 6.

43.

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis.

Phillips RS, Sung L, Ammann RA, Riley RD, Castagnola E, Haeusler GM, Klaassen R, Tissing WJ, Lehrnbecher T, Chisholm J, Hakim H, Ranasinghe N, Paesmans M, Hann IM, Stewart LA.

Br J Cancer. 2016 Jun 14;114(12):e17. doi: 10.1038/bjc.2016.137. Epub 2016 May 26. No abstract available.

44.

Strategies for Empiric Management of Pediatric Fever and Neutropenia in Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: A Systematic Review of Randomized Trials.

Robinson PD, Lehrnbecher T, Phillips R, Dupuis LL, Sung L.

J Clin Oncol. 2016 Jun 10;34(17):2054-60. doi: 10.1200/JCO.2015.65.8591. Epub 2016 Mar 28. Review.

PMID:
27022114
45.

Predicting microbiologically defined infection in febrile neutropenic episodes in children: global individual participant data multivariable meta-analysis.

Phillips RS, Sung L, Ammann RA, Riley RD, Castagnola E, Haeusler GM, Klaassen R, Tissing WJ, Lehrnbecher T, Chisholm J, Hakim H, Ranasinghe N, Paesmans M, Hann IM, Stewart LA; PICNICC Collaboration.

Br J Cancer. 2016 Mar 15;114(6):623-30. doi: 10.1038/bjc.2016.28. Epub 2016 Mar 8. Erratum in: Br J Cancer. 2016 Jun 14;114(12):e17.

46.

Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.

Hassler A, Bochennek K, Gilfert J, Perner C, Schöning S, Creutzig U, Reinhardt D, Lehrnbecher T.

Pediatr Blood Cancer. 2016 Jun;63(6):1070-4. doi: 10.1002/pbc.25917. Epub 2016 Jan 27.

PMID:
26814618
47.

Infectious complications in children with acute myeloid leukemia: decreased mortality in multicenter trial AML-BFM 2004.

Bochennek K, Hassler A, Perner C, Gilfert J, Schöning S, Klingebiel T, Reinhardt D, Creutzig U, Lehrnbecher T.

Blood Cancer J. 2016 Jan 15;6:e382. doi: 10.1038/bcj.2015.110.

48.

Biomarker-based diagnostic work-up of invasive pulmonary aspergillosis in immunocompromised paediatric patients--is Aspergillus PCR appropriate?

Buchheidt D, Reinwald M, Spiess B, Boch T, Hofmann WK, Groll AH, Lehrnbecher T; Working Group “Infections in Hematology and Oncology”, German Paul-Ehrlich-Society.

Mycoses. 2016 Feb;59(2):67-74. doi: 10.1111/myc.12443. Epub 2015 Dec 14. Review.

PMID:
26756571
49.

Classification of treatment-related mortality in children with cancer: a systematic assessment.

Alexander S, Pole JD, Gibson P, Lee M, Hesser T, Chi SN, Dvorak CC, Fisher B, Hasle H, Kanerva J, Möricke A, Phillips B, Raetz E, Rodriguez-Galindo C, Samarasinghe S, Schmiegelow K, Tissing W, Lehrnbecher T, Sung L; International Pediatric Oncology Mortality Classification Group.

Lancet Oncol. 2015 Dec;16(16):e604-10. doi: 10.1016/S1470-2045(15)00197-7. Review.

PMID:
26678213
50.

Natural killer cell-mediated damage of clinical isolates of mucormycetes.

Schmidt S, Schneider A, Demir A, Lass-Flörl C, Lehrnbecher T.

Mycoses. 2016 Jan;59(1):34-8. doi: 10.1111/myc.12431. Epub 2015 Nov 18.

PMID:
26578394

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