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Items: 35

1.

Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.

Leshets M, Ramamurthy D, Lisby M, Lehming N, Pines O.

Curr Genet. 2018 Jun;64(3):697-712. doi: 10.1007/s00294-017-0786-4. Epub 2017 Dec 4.

PMID:
29204698
2.

Human Fumarate Hydratase Is Dual Localized by an Alternative Transcription Initiation Mechanism.

Dik E, Naamati A, Asraf H, Lehming N, Pines O.

Traffic. 2016 Jul;17(7):720-32. doi: 10.1111/tra.12397. Epub 2016 May 6.

3.

Differential regulation of proinflammatory cytokine expression by mitogen-activated protein kinases in macrophages in response to intestinal parasite infection.

Lim MX, Png CW, Tay CY, Teo JD, Jiao H, Lehming N, Tan KS, Zhang Y.

Infect Immun. 2014 Nov;82(11):4789-801. doi: 10.1128/IAI.02279-14. Epub 2014 Aug 25.

4.

How the ubiquitin proteasome system regulates the regulators of transcription.

Ee G, Lehming N.

Transcription. 2012 Sep-Oct;3(5):235-9. doi: 10.4161/trns.21249. Epub 2012 Sep 1.

5.

Mediator acts upstream of the transcriptional activator Gal4.

Ang K, Ee G, Ang E, Koh E, Siew WL, Chan YM, Nur S, Tan YS, Lehming N.

PLoS Biol. 2012;10(3):e1001290. doi: 10.1371/journal.pbio.1001290. Epub 2012 Mar 27.

6.

Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite.

Chua CS, Low H, Lehming N, Sim TS.

Int J Biochem Cell Biol. 2012 Jan;44(1):233-45. doi: 10.1016/j.biocel.2011.10.021. Epub 2011 Nov 11.

PMID:
22100910
7.

The histone variant H2A.Z interconverts two stable epigenetic chromatin states.

Zhao J, Siew WL, Sun W, Lehming N.

Biochem J. 2011 Nov 1;439(3):487-95. doi: 10.1042/BJ20110791.

PMID:
21736558
8.

Galactose induction of the GAL1 gene requires conditional degradation of the Mig2 repressor.

Lim MK, Siew WL, Zhao J, Tay YC, Ang E, Lehming N.

Biochem J. 2011 May 1;435(3):641-9. doi: 10.1042/BJ20102034.

PMID:
21323640
9.

Transcriptional activation requires protection of the TATA-binding protein Tbp1 by the ubiquitin-specific protease Ubp3.

Chew BS, Siew WL, Xiao B, Lehming N.

Biochem J. 2010 Nov 1;431(3):391-9. doi: 10.1042/BJ20101152.

PMID:
20738257
10.

Degradation-resistant protein domains limit host cell processing and immune detection of mycobacteria.

Koh KW, Lehming N, Seah GT.

Mol Immunol. 2009 Apr;46(7):1312-8. doi: 10.1016/j.molimm.2008.11.008. Epub 2009 Jan 6.

PMID:
19128836
11.

Nhp6p and Med3p regulate gene expression by controlling the local subunit composition of RNA polymerase II.

Xue X, Lehming N.

J Mol Biol. 2008 May 30;379(2):212-30. doi: 10.1016/j.jmb.2008.03.069. Epub 2008 Apr 7.

PMID:
18448120
12.

Gal11p dosage-compensates transcriptional activator deletions via Taf14p.

Lim MK, Tang V, Le Saux A, Schüller J, Bongards C, Lehming N.

J Mol Biol. 2007 Nov 16;374(1):9-23. Epub 2007 Sep 11.

PMID:
17919657
13.

TFIIB/SUA7(E202G) is an allele-specific suppressor of TBP1(E186D).

Chew BS, Lehming N.

Biochem J. 2007 Sep 1;406(2):265-71.

14.

Global effects of histone modifications.

He H, Lehming N.

Brief Funct Genomic Proteomic. 2003 Oct;2(3):234-43. Review.

PMID:
15239926
15.

Analysis of protein-protein proximities using the split-ubiquitin system.

Lehming N.

Brief Funct Genomic Proteomic. 2002 Oct;1(3):230-8. Review.

PMID:
15239890
16.
17.
18.

Transcriptional activating regions target a cyclin-dependent kinase.

Ansari AZ, Koh SS, Zaman Z, Bongards C, Lehming N, Young RA, Ptashne M.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14706-9. Epub 2002 Nov 4.

19.
20.

Why Ppr1p is a weak activator of transcription.

Pätzold AJ, Lehming N.

FEBS Lett. 2001 Apr 6;494(1-2):64-8.

21.

Srb7p is a physical and physiological target of Tup1p.

Gromöller A, Lehming N.

EMBO J. 2000 Dec 15;19(24):6845-52.

22.
23.

Srb7p is essential for the activation of a subset of genes.

Gromöller A, Lehming N.

FEBS Lett. 2000 Oct 27;484(1):48-54.

24.

A new method for the selection of protein interactions in mammalian cells.

Rojo-Niersbach E, Morley D, Heck S, Lehming N.

Biochem J. 2000 Jun 15;348 Pt 3:585-90.

25.

Analysis of the in vivo interaction between a basic repressor and an acidic activator.

Wellhausen A, Lehming N.

FEBS Lett. 1999 Jun 25;453(3):299-304.

26.

Chromatin components as part of a putative transcriptional repressing complex.

Lehming N, Le Saux A, Schüller J, Ptashne M.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7322-6.

27.

Interactions of a Rel protein with its inhibitor.

Lehming N, McGuire S, Brickman JM, Ptashne M.

Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10242-6.

28.

An HMG-like protein that can switch a transcriptional activator to a repressor.

Lehming N, Thanos D, Brickman JM, Ma J, Maniatis T, Ptashne M.

Nature. 1994 Sep 8;371(6493):175-9.

PMID:
8072548
29.

New eukaryotic transcriptional repressors.

Saha S, Brickman JM, Lehming N, Ptashne M.

Nature. 1993 Jun 17;363(6430):648-52.

PMID:
8510759
30.

A model of the lac repressor-operator complex based on physical and genetic data.

Kisters-Woike B, Lehming N, Sartorius J, von Wilcken-Bergmann B, Müller-Hill B.

Eur J Biochem. 1991 Jun 1;198(2):411-9.

31.

The roles of residues 5 and 9 of the recognition helix of Lac repressor in lac operator binding.

Sartorius J, Lehming N, Kisters-Woike B, von Wilcken-Bergmann B, Müller-Hill B.

J Mol Biol. 1991 Mar 20;218(2):313-21.

PMID:
2010911
32.

Mutant lac repressors with new specificities hint at rules for protein--DNA recognition.

Lehming N, Sartorius J, Kisters-Woike B, von Wilcken-Bergmann B, Müller-Hill B.

EMBO J. 1990 Mar;9(3):615-21. Erratum in: EMBO J 1990 May;9(5):1674.

33.

lac repressor mutants with double or triple exchanges in the recognition helix bind specifically to lac operator variants with multiple exchanges.

Sartorius J, Lehming N, Kisters B, von Wilcken-Bergmann B, Müller-Hill B.

EMBO J. 1989 Apr;8(4):1265-70.

34.

Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences.

Lehming N, Sartorius J, Oehler S, von Wilcken-Bergmann B, Müller-Hill B.

Proc Natl Acad Sci U S A. 1988 Nov;85(21):7947-51.

35.

The interaction of the recognition helix of lac repressor with lac operator.

Lehming N, Sartorius J, Niemöller M, Genenger G, v Wilcken-Bergmann B, Müller-Hill B.

EMBO J. 1987 Oct;6(10):3145-53.

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