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Items: 1 to 50 of 609

1.

Understanding mitochondrial DNA maintenance disorders at the single muscle fibre level.

Lehmann D, Tuppen HAL, Campbell GE, Alston CL, Lawless C, Rosa HS, Rocha MC, Reeve AK, Nicholls TJ, Deschauer M, Zierz S, Taylor RW, Turnbull DM, Vincent AE.

Nucleic Acids Res. 2019 Aug 22;47(14):7430-7443. doi: 10.1093/nar/gkz472.

PMID:
31147703
2.

Abnormal aortic flow profiles persist after aortic valve replacement in the majority of patients with aortic valve disease: how model-based personalized therapy planning could improve results. A pilot study approach.

Nordmeyer S, Hellmeier F, Yevtushenko P, Kelm M, Lee CB, Lehmann D, Kropf S, Berger F, Falk V, Knosalla C, Kuehne T, Goubergrits L.

Eur J Cardiothorac Surg. 2019 May 25. pii: ezz149. doi: 10.1093/ejcts/ezz149. [Epub ahead of print]

PMID:
31131388
3.

Variables associated with pediatric emergency department visits for uncontrolled pain in postoperative adenotonsillectomy patients.

Lavin J, Lehmann D, Silva AL, Bai G, Hebal F, Manworren R, Stake C, Rychlik K, Billings KR.

Int J Pediatr Otorhinolaryngol. 2019 Aug;123:10-14. doi: 10.1016/j.ijporl.2019.04.038. Epub 2019 Apr 26.

PMID:
31054535
4.

Australian Aboriginal children have higher hospitalization rates for otitis media but lower surgical procedures than non-Aboriginal children: A record linkage population-based cohort study.

Westphal DW, Lehmann D, Williams SA, Richmond PC, Lannigan FJ, Fathima P, Blyth CC, Moore HC.

PLoS One. 2019 Apr 23;14(4):e0215483. doi: 10.1371/journal.pone.0215483. eCollection 2019.

5.

Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol.

Fitze DP, Franchi M, Popp WL, Ruoss S, Catuogno S, Camenisch K, Lehmann D, Schmied CM, Niederseer D, Frey WO, Flück M.

JMIR Res Protoc. 2019 Mar 27;8(3):e10970. doi: 10.2196/10970.

6.

The epidemiological transition in Papua New Guinea: new evidence from verbal autopsy studies.

Gouda HN, Hazard RH, Maraga S, Flaxman AD, Stewart A, Joseph JC, Rarau P, Wangnapi R, Poka H, Serina P, Phuanukoonnon S, Pham BN, Vano M, Lupiwa S, Sie A, Kave H, Lehmann D, Siba P, Lopez AD, Riley ID.

Int J Epidemiol. 2019 Mar 26. pii: dyz018. doi: 10.1093/ije/dyz018. [Epub ahead of print]

PMID:
30915430
7.

The Epistasis Project: A Multi-Cohort Study of the Effects of BDNF, DBH, and SORT1 Epistasis on Alzheimer's Disease Risk.

Belbin O, Morgan K, Medway C, Warden D, Cortina-Borja M, van Duijn CM, Adams HHH, Frank-Garcia A, Brookes K, Sánchez-Juan P, Alvarez V, Heun R, Kölsch H, Coto E, Kehoe PG, Rodriguez-Rodriguez E, Bullido MJ, Ikram MA, Smith AD, Lehmann DJ.

J Alzheimers Dis. 2019;68(4):1535-1547. doi: 10.3233/JAD-181116.

PMID:
30909233
8.

Normal FGF-21-Serum Levels in Patients with Carnitine Palmitoyltransferase II (CPT II) Deficiency.

Motlagh Scholle L, Lehmann D, Joshi PR, Zierz S.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1400. doi: 10.3390/ijms20061400.

9.

Detection of phenol contamination in RNA samples and its impact on qRT-PCR results.

Unger C, Lokmer N, Lehmann D, Axmann IM.

Anal Biochem. 2019 Apr 15;571:49-52. doi: 10.1016/j.ab.2019.02.002. Epub 2019 Feb 8.

PMID:
30742799
10.

Immunogenicity and Immune Memory after a Pneumococcal Polysaccharide Vaccine Booster in a High-Risk Population Primed with 10-Valent or 13-Valent Pneumococcal Conjugate Vaccine: A Randomized Controlled Trial in Papua New Guinean Children.

van den Biggelaar AHJ, Pomat WS, Masiria G, Wana S, Nivio B, Francis J, Ford R, Passey M, Kirkham LA, Jacoby P, Lehmann D, Richmond P; 10v13v PCV Trial Team.

Vaccines (Basel). 2019 Feb 4;7(1). pii: E17. doi: 10.3390/vaccines7010017.

11.

An integrative systems approach identifies novel candidates in Marfan syndrome-related pathophysiology.

Bhushan R, Altinbas L, Jäger M, Zaradzki M, Lehmann D, Timmermann B, Clayton NP, Zhu Y, Kallenbach K, Kararigas G, Robinson PN.

J Cell Mol Med. 2019 Apr;23(4):2526-2535. doi: 10.1111/jcmm.14137. Epub 2019 Jan 24.

12.

Cross-reactivity between halogenated platinum salts in an immediate-type respiratory hypersensitivity model.

Lehmann DM, Williams WC.

Inhal Toxicol. 2018 Sep - Oct;30(11-12):472-481. doi: 10.1080/08958378.2018.1554015. Epub 2019 Jan 18.

PMID:
30654668
13.

Workshop on Pesticide Exposure Assessment Paradigm for Non-Apis Bees: Foundation and Summaries.

Boyle NK, Pitts-Singer TL, Abbott J, Alix A, Cox-Foster DL, Hinarejos S, Lehmann DM, Morandin L, O'Neill B, Raine NE, Singh R, Thompson HM, Williams NM, Steeger T.

Environ Entomol. 2019 Feb 13;48(1):4-11. doi: 10.1093/ee/nvy103.

PMID:
30508116
14.

Comparison of Pesticide Exposure in Honey Bees (Hymenoptera: Apidae) and Bumble Bees (Hymenoptera: Apidae): Implications for Risk Assessments.

Gradish AE, van der Steen J, Scott-Dupree CD, Cabrera AR, Cutler GC, Goulson D, Klein O, Lehmann DM, Lückmann J, O'Neill B, Raine NE, Sharma B, Thompson H.

Environ Entomol. 2019 Feb 13;48(1):12-21. doi: 10.1093/ee/nvy168.

PMID:
30508078
15.

Coordinated Assembly of the Bacillus anthracis Coat and Exosporium during Bacterial Spore Outer Layer Formation.

Boone TJ, Mallozzi M, Nelson A, Thompson B, Khemmani M, Lehmann D, Dunkle A, Hoeprich P, Rasley A, Stewart G, Driks A.

MBio. 2018 Nov 6;9(6). pii: e01166-18. doi: 10.1128/mBio.01166-18.

16.

Genetic influence of plasma homocysteine on Alzheimer's disease.

Lehmann DJ, Cortina-Borja M.

Neurobiol Aging. 2019 Apr;76:217-218. doi: 10.1016/j.neurobiolaging.2018.08.028. Epub 2018 Oct 11. No abstract available.

PMID:
30392994
17.

Skin sensitization testing needs and data uses by US regulatory and research agencies.

Strickland J, Daniel AB, Allen D, Aguila C, Ahir S, Bancos S, Craig E, Germolec D, Ghosh C, Hudson NL, Jacobs A, Lehmann DM, Matheson J, Reinke EN, Sadrieh N, Vukmanovic S, Kleinstreuer N.

Arch Toxicol. 2019 Feb;93(2):273-291. doi: 10.1007/s00204-018-2341-6. Epub 2018 Oct 30.

PMID:
30377734
18.

Moraxella catarrhalis Restriction-Modification Systems Are Associated with Phylogenetic Lineage and Disease.

Blakeway LV, Tan A, Lappan R, Ariff A, Pickering JL, Peacock CS, Blyth CC, Kahler CM, Chang BJ, Lehmann D, Kirkham LS, Murphy TF, Jennings MP, Bakaletz LO, Atack JM, Peak IR, Seib KL.

Genome Biol Evol. 2018 Nov 1;10(11):2932-2946. doi: 10.1093/gbe/evy226.

19.

Safety and Immunogenicity of Pneumococcal Conjugate Vaccines in a High-risk Population: A Randomized Controlled Trial of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccine in Papua New Guinean Infants.

Pomat WS, van den Biggelaar AHJ, Wana S, Francis JP, Solomon V, Greenhill AR, Ford R, Orami T, Passey M, Jacoby P, Kirkham LA, Lehmann D, Richmond PC; 10v13v PCV Trial Team .

Clin Infect Dis. 2019 Apr 24;68(9):1472-1481. doi: 10.1093/cid/ciy743.

20.

Development and utilization of a unique in vitro antigen presentation co-culture model for detection of immunomodulating substances.

Lehmann DM, Williams WC.

Toxicol In Vitro. 2018 Dec;53:20-28. doi: 10.1016/j.tiv.2018.06.025. Epub 2018 Jul 23.

PMID:
30048737
21.

Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment.

Lehmann DM.

Methods Mol Biol. 2018;1803:101-116. doi: 10.1007/978-1-4939-8549-4_8.

PMID:
29882136
22.

Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countries: a protocol for a prospective observational study.

Chan J, Nguyen CD, Lai JYR, Dunne EM, Andrews R, Blyth CC, Datta S, Fox K, Ford R, Hinds J, La Vincente S, Lehmann D, Lim R, Mungun T, Newton PN, Phetsouvanh R, Pomat WS, Xeuatvongsa A, von Mollendorf C, Dance DAB, Satzke C, Muholland K, Russell FM; PneuCAPTIVE Protocol Group.

BMJ Open. 2018 May 18;8(5):e021512. doi: 10.1136/bmjopen-2018-021512.

23.

Perinatal Risk Factors Associated With Gastroenteritis Hospitalizations in Aboriginal and Non-Aboriginal Children in Western Australia (2000-2012): A Record Linkage Cohort Study.

Fathima P, Snelling TL, de Klerk N, Lehmann D, Blyth CC, Waddington CS, Moore HC.

Pediatr Infect Dis J. 2019 Feb;38(2):169-175. doi: 10.1097/INF.0000000000002063.

PMID:
29620723
24.
25.

Validation and Clinical Utility of the hERG IC50:Cmax Ratio to Determine the Risk of Drug-Induced Torsades de Pointes: A Meta-Analysis.

Lehmann DF, Eggleston WD, Wang D.

Pharmacotherapy. 2018 Mar;38(3):341-348. doi: 10.1002/phar.2087. Epub 2018 Feb 19.

PMID:
29380488
26.

Integrated decision strategies for skin sensitization hazard.

Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W.

J Appl Toxicol. 2018 Mar;38(3):432. doi: 10.1002/jat.3572. Epub 2017 Nov 29. No abstract available.

PMID:
29363186
27.

FGF-21 as a Potential Biomarker for Mitochondrial Diseases.

Scholle LM, Lehmann D, Deschauer M, Kraya T, Zierz S.

Curr Med Chem. 2018;25(18):2070-2081. doi: 10.2174/0929867325666180111094336. Review.

PMID:
29332568
28.

Utility of food pellets containing 1-aminobenzotriazole for longer term in vivo inhibition of cytochrome P450 in mice.

Stringer R, Cordier V, Afatsawo C, Arabin P, Desrayaud S, Hoffmann L, Lehmann D, Lowe PJ, Risser F, Thiel J, Widmer T, Wipfli P, Bigaud M.

Xenobiotica. 2019 Jan;49(1):13-21. doi: 10.1080/00498254.2017.1418542. Epub 2018 Jan 29.

PMID:
29299977
29.

Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea.

Lehmann D, Kirarock W, van den Biggelaar AHJ, Passey M, Jacoby P, Saleu G, Masiria G, Nivio B, Greenhill A, Orami T, Francis J, Ford R, Kirkham LA, Solomon V, Richmond PC, Pomat WS; 10v13v PCV trial team.

Pneumonia (Nathan). 2017 Dec 25;9:20. doi: 10.1186/s41479-017-0044-z. eCollection 2017.

30.

Strengthening Instrumental Variables Through Weighting.

Lehmann D, Li Y, Saran R, Li Y.

Stat Biosci. 2017 Dec;9(2):320-338. doi: 10.1007/s12561-016-9149-9. Epub 2016 May 26.

31.

The Impact of Pneumococcal Vaccination on Bacterial and Viral Pneumonia in Western Australian Children: Record Linkage Cohort Study of 469589 Births, 1996-2012.

Fathima P, Blyth CC, Lehmann D, Lim FJ, Abdalla T, de Klerk N, Moore HC.

Clin Infect Dis. 2018 Mar 19;66(7):1075-1085. doi: 10.1093/cid/cix923.

PMID:
29069315
32.

Pneumococcal responses are similar in Papua New Guinean children aged 3-5 years vaccinated in infancy with pneumococcal polysaccharide vaccine with or without prior pneumococcal conjugate vaccine, or without pneumococcal vaccination.

van den Biggelaar AHJ, Richmond PC, Fuery A, Anderson D, Opa C, Saleu G, Lai M, Francis JP, Alpers MP, Pomat WS, Lehmann D.

PLoS One. 2017 Oct 13;12(10):e0185877. doi: 10.1371/journal.pone.0185877. eCollection 2017.

33.

Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination in the Western Australian Aboriginal population.

Collins DA, Hoskins A, Snelling T, Senasinghe K, Bowman J, Stemberger NA, Leach AJ, Lehmann D.

Pneumonia (Nathan). 2017 Sep 25;9:14. doi: 10.1186/s41479-017-0038-x. eCollection 2017.

34.

Understanding a Sequence of Sequences: Visual Exploration of Categorical States in Lake Sediment Cores.

Unger A, Drager N, Sips M, Lehmann DJ.

IEEE Trans Vis Comput Graph. 2018 Jan;24(1):66-76. doi: 10.1109/TVCG.2017.2744686. Epub 2017 Aug 30.

PMID:
28866556
35.

Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges.

Blyth CC, Ford R, Sapura J, Kumani T, Masiria G, Kave J, Yuasi L, Greenhill A, Hwaihwanje I, Lang A, Lehmann D, Pomat W; Papua New Guinea Pneumonia and Meningitis Etiology Study Team.

Pneumonia (Nathan). 2017 Mar 5;9:5. doi: 10.1186/s41479-017-0029-y. eCollection 2017.

36.

Aboriginal and non-Aboriginal children in Western Australia carry different serotypes of pneumococci with different antimicrobial susceptibility profiles.

Dunne EM, Carville K, Riley TV, Bowman J, Leach AJ, Cripps AW, Murphy D, Jacoby P, Lehmann D; Kalgoorlie Otitis Media Research Project Team.

Pneumonia (Nathan). 2016 Sep 5;8:15. doi: 10.1186/s41479-016-0015-9. eCollection 2016.

37.

Geographic consistency in dominant, non-typeable Haemophilus influenzae genotypes colonising four distinct Australian paediatric groups: a cohort study.

Smith-Vaughan HC, Beissbarth J, Bowman J, Hare KM, Price EP, Pickering J, Lehmann D, Chang AB, Morris PS, Marsh RL, Leach AJ.

Pneumonia (Nathan). 2016 Aug 18;8:13. doi: 10.1186/s41479-016-0013-y. eCollection 2016.

38.

A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort study.

Francis JP, Richmond PC, Michael A, Siba PM, Jacoby P, Hales BJ, Thomas WR, Lehmann D, Pomat WS, van den Biggelaar AHJ.

Pneumonia (Nathan). 2016 Aug 15;8:12. doi: 10.1186/s41479-016-0014-x. eCollection 2016.

39.

Limited impact of neonatal or early infant schedules of 7-valent pneumococcal conjugate vaccination on nasopharyngeal carriage of Streptococcus pneumoniae in Papua New Guinean children: A randomized controlled trial.

Aho C, Michael A, Yoannes M, Greenhill A, Jacoby P, Reeder J, Pomat W, Saleu G, Namuigi P, Phuanukoonnon S, Smith-Vaughan H, Leach AJ, Richmond P, Lehmann D; Neonatal Pneumococcal Conjugate Vaccine Trial Study Team.

Vaccine Rep. 2016 Dec;6:36-43. doi: 10.1016/j.vacrep.2016.08.002.

40.

The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development.

Post M, Cuapio A, Osl M, Lehmann D, Resch U, Davies DM, Bilban M, Schlechta B, Eppel W, Nathwani A, Stoiber D, Spanholtz J, Casanova E, Hofer E.

Front Immunol. 2017 May 15;8:535. doi: 10.3389/fimmu.2017.00535. eCollection 2017.

41.

The LloydRelaxer: An Approach to Minimize Scaling Effects for Multivariate Projections.

Lehmann DJ, Theisel H.

IEEE Trans Vis Comput Graph. 2018 Aug;24(8):2424-2439. doi: 10.1109/TVCG.2017.2705189. Epub 2017 May 17.

PMID:
28534778
42.

Camptocormia and shuffling gait due to a novel MT-TV mutation: Diagnostic pitfalls.

Reimann J, Lehmann D, Hardy SA, Falkous G, Knowles CV, Jones RL, Kunz WS, Taylor RW, Kornblum C.

Neurol Genet. 2017 Apr 5;3(3):e147. doi: 10.1212/NXG.0000000000000147. eCollection 2017 Jun. No abstract available.

43.

Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine.

Weilhammer D, Dunkle AD, Blanchette CD, Fischer NO, Corzett M, Lehmann D, Boone T, Hoeprich P, Driks A, Rasley A.

Vaccine. 2017 Mar 13;35(11):1475-1481. doi: 10.1016/j.vaccine.2017.02.004. Epub 2017 Feb 14.

PMID:
28214044
44.

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement.

Yehuda Y, Blumenfeld B, Lehmann D, Simon I.

J Vis Exp. 2017 Jan 19;(119). doi: 10.3791/55157.

45.

Indicators for continuous quality improvement for otitis media in primary health care for Aboriginal and Torres Strait Islander children.

Sibthorpe B, Agostino J, Coates H, Weeks S, Lehmann D, Wood M, Lannigan F, McAullay D.

Aust J Prim Health. 2017 Apr;23(1):1-9. doi: 10.1071/PY16096.

PMID:
28088980
46.

Prediction of skin sensitization potency using machine learning approaches.

Zang Q, Paris M, Lehmann DM, Bell S, Kleinstreuer N, Allen D, Matheson J, Jacobs A, Casey W, Strickland J.

J Appl Toxicol. 2017 Jul;37(7):792-805. doi: 10.1002/jat.3424. Epub 2017 Jan 10.

47.

Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features.

Lehmann D, Motlagh L, Robaa D, Zierz S.

Int J Mol Sci. 2017 Jan 3;18(1). pii: E82. doi: 10.3390/ijms18010082. Review.

48.

Temporal Characteristics of EEG Microstates Mediate Trial-by-Trial Risk Taking.

Pedroni A, Gianotti LR, Koenig T, Lehmann D, Faber P, Knoch D.

Brain Topogr. 2017 Jan;30(1):149-159. doi: 10.1007/s10548-016-0539-6. Epub 2016 Dec 8.

PMID:
27933418
49.

Cord blood Streptococcus pneumoniae-specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea.

Francis JP, Richmond PC, Strickland D, Prescott SL, Pomat WS, Michael A, Nadal-Sims MA, Edwards-Devitt CJ, Holt PG, Lehmann D, van den Biggelaar AH.

Clin Exp Immunol. 2017 Mar;187(3):408-417. doi: 10.1111/cei.12902. Epub 2016 Dec 18.

50.

Peripheral neuropathy in patients with CPEO associated with single and multiple mtDNA deletions.

Lehmann D, Kornhuber ME, Clajus C, Alston CL, Wienke A, Deschauer M, Taylor RW, Zierz S.

Neurol Genet. 2016 Oct 19;2(6):e113. eCollection 2016 Dec.

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