Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 85

1.

C. elegans DPY-19 is a C-mannosyltransferase glycosylating thrombospondin repeats.

Buettner FF, Ashikov A, Tiemann B, Lehle L, Bakker H.

Mol Cell. 2013 Apr 25;50(2):295-302. doi: 10.1016/j.molcel.2013.03.003. Epub 2013 Apr 4.

2.

Identification of alg3 in the mushroom-forming fungus Schizophyllum commune and analysis of the Δalg3 knockout mutant.

Berends E, Lehle L, Henquet M, Hesselink T, Wösten HA, Lugones LG, Bosch D.

Glycobiology. 2013 Feb;23(2):147-54. doi: 10.1093/glycob/cws135. Epub 2012 Sep 20.

PMID:
22997240
3.

Defining the phenotype in congenital disorder of glycosylation due to ALG1 mutations.

Morava E, Vodopiutz J, Lefeber DJ, Janecke AR, Schmidt WM, Lechner S, Item CB, Sykut-Cegielska J, Adamowicz M, Wierzba J, Zhang ZH, Mihalek I, Stockler S, Bodamer OA, Lehle L, Wevers RA.

Pediatrics. 2012 Oct;130(4):e1034-9. doi: 10.1542/peds.2011-2711. Epub 2012 Sep 10.

PMID:
22966035
4.

More than 40 years of glycobiology in Regensburg.

Tanner W, Lehle L.

Biochem Biophys Res Commun. 2012 Aug 31;425(3):578-82. doi: 10.1016/j.bbrc.2012.08.001. No abstract available.

PMID:
22925677
5.

Gene identification in the congenital disorders of glycosylation type I by whole-exome sequencing.

Timal S, Hoischen A, Lehle L, Adamowicz M, Huijben K, Sykut-Cegielska J, Paprocka J, Jamroz E, van Spronsen FJ, Körner C, Gilissen C, Rodenburg RJ, Eidhof I, Van den Heuvel L, Thiel C, Wevers RA, Morava E, Veltman J, Lefeber DJ.

Hum Mol Genet. 2012 Oct 1;21(19):4151-61. doi: 10.1093/hmg/dds123. Epub 2012 Apr 5.

PMID:
22492991
6.

The essential endoplasmic reticulum chaperone Rot1 is required for protein N- and O-glycosylation in yeast.

Pasikowska M, Palamarczyk G, Lehle L.

Glycobiology. 2012 Jul;22(7):939-47. doi: 10.1093/glycob/cws068. Epub 2012 Apr 4.

PMID:
22492205
7.

Congenital disorder of glycosylation type Ij (CDG-Ij, DPAGT1-CDG): extending the clinical and molecular spectrum of a rare disease.

Würde AE, Reunert J, Rust S, Hertzberg C, Haverkämper S, Nürnberg G, Nürnberg P, Lehle L, Rossi R, Marquardt T.

Mol Genet Metab. 2012 Apr;105(4):634-41. doi: 10.1016/j.ymgme.2012.01.001. Epub 2012 Jan 9.

PMID:
22304930
8.

Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation.

Lefeber DJ, de Brouwer AP, Morava E, Riemersma M, Schuurs-Hoeijmakers JH, Absmanner B, Verrijp K, van den Akker WM, Huijben K, Steenbergen G, van Reeuwijk J, Jozwiak A, Zucker N, Lorber A, Lammens M, Knopf C, van Bokhoven H, Grünewald S, Lehle L, Kapusta L, Mandel H, Wevers RA.

PLoS Genet. 2011 Dec;7(12):e1002427. doi: 10.1371/journal.pgen.1002427. Epub 2011 Dec 29.

9.

A novel cerebello-ocular syndrome with abnormal glycosylation due to abnormalities in dolichol metabolism.

Morava E, Wevers RA, Cantagrel V, Hoefsloot LH, Al-Gazali L, Schoots J, van Rooij A, Huijben K, van Ravenswaaij-Arts CM, Jongmans MC, Sykut-Cegielska J, Hoffmann GF, Bluemel P, Adamowicz M, van Reeuwijk J, Ng BG, Bergman JE, van Bokhoven H, Körner C, Babovic-Vuksanovic D, Willemsen MA, Gleeson JG, Lehle L, de Brouwer AP, Lefeber DJ.

Brain. 2010 Nov;133(11):3210-20. doi: 10.1093/brain/awq261. Epub 2010 Sep 17.

10.

SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder.

Cantagrel V, Lefeber DJ, Ng BG, Guan Z, Silhavy JL, Bielas SL, Lehle L, Hombauer H, Adamowicz M, Swiezewska E, De Brouwer AP, Blümel P, Sykut-Cegielska J, Houliston S, Swistun D, Ali BR, Dobyns WB, Babovic-Vuksanovic D, van Bokhoven H, Wevers RA, Raetz CR, Freeze HH, Morava E, Al-Gazali L, Gleeson JG.

Cell. 2010 Jul 23;142(2):203-17. doi: 10.1016/j.cell.2010.06.001. Epub 2010 Jul 15.

11.

A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.

Rind N, Schmeiser V, Thiel C, Absmanner B, Lübbehusen J, Hocks J, Apeshiotis N, Wilichowski E, Lehle L, Körner C.

Hum Mol Genet. 2010 Apr 15;19(8):1413-24. doi: 10.1093/hmg/ddq016. Epub 2010 Jan 15.

PMID:
20080937
13.

Deficiency of Dol-P-Man synthase subunit DPM3 bridges the congenital disorders of glycosylation with the dystroglycanopathies.

Lefeber DJ, Schönberger J, Morava E, Guillard M, Huyben KM, Verrijp K, Grafakou O, Evangeliou A, Preijers FW, Manta P, Yildiz J, Grünewald S, Spilioti M, van den Elzen C, Klein D, Hess D, Ashida H, Hofsteenge J, Maeda Y, van den Heuvel L, Lammens M, Lehle L, Wevers RA.

Am J Hum Genet. 2009 Jul;85(1):76-86. doi: 10.1016/j.ajhg.2009.06.006. Epub 2009 Jul 2.

14.
15.

The yeast oligosaccharyltransferase complex can be replaced by STT3 from Leishmania major.

Hese K, Otto C, Routier FH, Lehle L.

Glycobiology. 2009 Feb;19(2):160-71. doi: 10.1093/glycob/cwn118. Epub 2008 Oct 25.

PMID:
18955371
16.

Identification of the gene encoding the alpha1,3-mannosyltransferase (ALG3) in Arabidopsis and characterization of downstream n-glycan processing.

Henquet M, Lehle L, Schreuder M, Rouwendal G, Molthoff J, Helsper J, van der Krol S, Bosch D.

Plant Cell. 2008 Jun;20(6):1652-64. doi: 10.1105/tpc.108.060731. Epub 2008 Jun 20.

17.

Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging.

Hauptmann P, Lehle L.

J Biol Chem. 2008 Jul 4;283(27):19151-63. doi: 10.1074/jbc.M801303200. Epub 2008 May 12.

18.

Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases.

Lehle L, Strahl S, Tanner W.

Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6802-18. Review.

PMID:
17024709
19.

Pir proteins of Saccharomyces cerevisiae are attached to beta-1,3-glucan by a new protein-carbohydrate linkage.

Ecker M, Deutzmann R, Lehle L, Mrsa V, Tanner W.

J Biol Chem. 2006 Apr 28;281(17):11523-9. Epub 2006 Feb 22.

20.

Defects in N-glycosylation induce apoptosis in yeast.

Hauptmann P, Riel C, Kunz-Schughart LA, Fröhlich KU, Madeo F, Lehle L.

Mol Microbiol. 2006 Feb;59(3):765-78.

21.
22.
23.

Congenital disorder of glycosylation type Ik (CDG-Ik): a defect of mannosyltransferase I.

Kranz C, Denecke J, Lehle L, Sohlbach K, Jeske S, Meinhardt F, Rossi R, Gudowius S, Marquardt T.

Am J Hum Genet. 2004 Mar;74(3):545-51. Epub 2004 Feb 17.

24.

Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik.

Schwarz M, Thiel C, Lübbehusen J, Dorland B, de Koning T, von Figura K, Lehle L, Körner C.

Am J Hum Genet. 2004 Mar;74(3):472-81. Epub 2004 Feb 16.

25.

The auxin-induced maize gene ZmSAUR2 encodes a short-lived nuclear protein expressed in elongating tissues.

Knauss S, Rohrmeier T, Lehle L.

J Biol Chem. 2003 Jun 27;278(26):23936-43. Epub 2003 Apr 14.

26.

A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis.

Thiel C, Schwarz M, Peng J, Grzmil M, Hasilik M, Braulke T, Kohlschütter A, von Figura K, Lehle L, Körner C.

J Biol Chem. 2003 Jun 20;278(25):22498-505. Epub 2003 Apr 8.

27.

Overexpression of GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae corrects defects in dolichol-linked saccharide formation and protein glycosylation.

Janik A, Sosnowska M, Kruszewska J, Krotkiewski H, Lehle L, Palamarczyk G.

Biochim Biophys Acta. 2003 Apr 7;1621(1):22-30.

PMID:
12667607
28.

Deficiency of dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig.

Thiel C, Schwarz M, Hasilik M, Grieben U, Hanefeld F, Lehle L, von Figura K, Körner C.

Biochem J. 2002 Oct 1;367(Pt 1):195-201.

29.
30.
31.

Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.

Körner C, Knauer R, Stephani U, Marquardt T, Lehle L, von Figura K.

EMBO J. 1999 Dec 1;18(23):6816-22.

33.
35.

The oligosaccharyltransferase complex from yeast.

Knauer R, Lehle L.

Biochim Biophys Acta. 1999 Jan 6;1426(2):259-73. Review.

PMID:
9878773
36.

Carbohydrate-deficient glycoprotein syndrome type V: deficiency of dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase.

Körner C, Knauer R, Holzbach U, Hanefeld F, Lehle L, von Figura K.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13200-5.

37.

Ca(2+)-ATPases of Saccharomyces cerevisiae: diversity and possible role in protein sorting.

Okorokov LA, Lehle L.

FEMS Microbiol Lett. 1998 May 1;162(1):83-91.

40.

STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo.

Zufferey R, Knauer R, Burda P, Stagljar I, te Heesen S, Lehle L, Aebi M.

EMBO J. 1995 Oct 16;14(20):4949-60.

42.
43.

The N-oligosaccharyltransferase complex from yeast.

Knauer R, Lehle L.

FEBS Lett. 1994 May 9;344(1):83-6.

44.

Normal N-oligosaccharyltransferase activity in fibroblasts from patients with carbohydrate-deficient glycoprotein syndrome.

Knauer R, Lehle L, Hanefeld F, von Figura K.

J Inherit Metab Dis. 1994;17(5):541-4. No abstract available.

PMID:
7837759
45.

A novel primary Ca(2+)-transport system from Saccharomyces cerevisiae.

Okorokov LA, Tanner W, Lehle L.

Eur J Biochem. 1993 Sep 1;216(2):573-7.

46.

WIP1, a wound-inducible gene from maize with homology to Bowman-Birk proteinase inhibitors.

Rohrmeier T, Lehle L.

Plant Mol Biol. 1993 Aug;22(5):783-92.

PMID:
8358030
47.
48.

Ty4, a new retrotransposon from Saccharomyces cerevisiae, flanked by tau-elements.

Janetzky B, Lehle L.

J Biol Chem. 1992 Oct 5;267(28):19798-805.

49.

The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro.

te Heesen S, Janetzky B, Lehle L, Aebi M.

EMBO J. 1992 Jun;11(6):2071-5.

50.

Protein glycosylation in yeast.

Lehle L.

Antonie Van Leeuwenhoek. 1992 Feb;61(2):133-4. Review. No abstract available.

PMID:
1580614

Supplemental Content

Support Center