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Adverse Birth Outcomes as Indicators of Poor Fetal Growth Conditions in a French Newborn Population-A Stratified Analysis by Neighborhood Deprivation Level.

Kihal-Talantikite W, Le Nouveau P, Legendre P, Zmirou Navier D, Danzon A, Carayol M, Deguen S.

Int J Environ Res Public Health. 2019 Oct 23;16(21). pii: E4069. doi: 10.3390/ijerph16214069.


Is there today a place for corticosteroids in the treatment of scleroderma?

Blagojevic J, Legendre P, Matucci-Cerinic M, Mouthon L.

Autoimmun Rev. 2019 Dec;18(12):102403. doi: 10.1016/j.autrev.2019.102403. Epub 2019 Oct 19. Review.


The cerebrospinal fluid CD4/CD8 ratio and interleukin-6 and -10 levels in neurosarcoidosis: a multicenter, pragmatic, comparative study.

Chazal T, Costopoulos M, Maillart E, Fleury C, Psimaras D, Legendre P, Pineton de Chambrun M, Haroche J, Lubetzki C, Amoura Z, Legarff-Tavernier M, Cohen Aubart F.

Eur J Neurol. 2019 Oct;26(10):1274-1280. doi: 10.1111/ene.13975. Epub 2019 Jun 24.


A temporal beta-diversity index to identify sites that have changed in exceptional ways in space-time surveys.

Legendre P.

Ecol Evol. 2019 Feb 18;9(6):3500-3514. doi: 10.1002/ece3.4984. eCollection 2019 Mar.


Microglia: Brain cells on the move.

Smolders SM, Kessels S, Vangansewinkel T, Rigo JM, Legendre P, Brône B.

Prog Neurobiol. 2019 Jul;178:101612. doi: 10.1016/j.pneurobio.2019.04.001. Epub 2019 Apr 4. Review.


Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence.

Dupont A, Soukaseum C, Cheptou M, Adam F, Nipoti T, Lourenco-Rodrigues MD, Legendre P, Proulle V, Rauch A, Kawecki C, Bryckaert M, Rosa JP, Paris C, Ternisien C, Boisseau P, Goudemand J, Borgel D, Lasne D, Maurice P, Lenting PJ, Denis CV, Susen S, Kauskot A.

Haematologica. 2019 Feb 28. pii: haematol.2018.206250. doi: 10.3324/haematol.2018.206250. [Epub ahead of print]


Premature Adult Death and Equity Impact of a Reduction of NO₂, PM10, and PM2.5 Levels in Paris-A Health Impact Assessment Study Conducted at the Census Block Level.

Kihal-Talantikite W, Legendre P, Le Nouveau P, Deguen S.

Int J Environ Res Public Health. 2018 Dec 24;16(1). pii: E38. doi: 10.3390/ijerph16010038.


Glomeruloid haemangioma: a possible consequence of elevated VEGF in POEMS and Erdheim-Chester disease.

Legendre P, Norkowski E, Le Pelletier F, Miyara M, Choquet S, Haroche J, Brocheriou I, Barete S.

Eur J Dermatol. 2018 Dec 1;28(6):784-789. doi: 10.1684/ejd.2018.3451.


Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos.

Angelim MKSC, Maia LMSS, Mouffle C, Ginhoux F, Low D, Amancio-Dos-Santos A, Makhoul J, Le Corronc H, Mangin JM, Legendre P.

Glia. 2018 Nov;66(11):2470-2486. doi: 10.1002/glia.23499. Epub 2018 Sep 25.


Negative relationships between species richness and temporal variability are common but weak in natural systems.

Houlahan JE, Currie DJ, Cottenie K, Cumming GS, Findlay CS, Fuhlendorf SD, Legendre P, Muldavin EH, Noble D, Russell R, Stevens RD, Willis TJ, Wondzell SM.

Ecology. 2018 Nov;99(11):2592-2604. doi: 10.1002/ecy.2514. Epub 2018 Oct 12.


A factor VIII-nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation.

Muczynski V, Casari C, Moreau F, Aymé G, Kawecki C, Legendre P, Proulle V, Christophe OD, Denis CV, Lenting PJ.

Blood. 2018 Sep 13;132(11):1193-1197. doi: 10.1182/blood-2018-01-829523. Epub 2018 Jul 31.


Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks.

Boeri J, Le Corronc H, Lejeune FX, Le Bras B, Mouffle C, Angelim MKSC, Mangin JM, Branchereau P, Legendre P, Czarnecki A.

J Neurosci. 2018 Aug 29;38(35):7667-7682. doi: 10.1523/JNEUROSCI.3203-17.2018. Epub 2018 Jul 16.


Axoglial synapses are formed onto pioneer oligodendrocyte precursor cells at the onset of spinal cord gliogenesis.

Osterstock G, Le Bras B, Arulkandarajah KH, Le Corronc H, Czarnecki A, Mouffle C, Bullier E, Legendre P, Mangin JM.

Glia. 2018 Aug;66(8):1678-1694. doi: 10.1002/glia.23331. Epub 2018 Mar 30.


Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor.

Wohner N, Muczynski V, Mohamadi A, Legendre P, Proulle V, Aymé G, Christophe OD, Lenting PJ, Denis CV, Casari C.

Haematologica. 2018 Apr;103(4):728-737. doi: 10.3324/haematol.2017.175216. Epub 2018 Jan 11.


Hypocoagulability as assessed by thrombin generation test in newly-diagnosed patients with multiple myeloma.

Legendre P, Verstraete E, Martin M, Poinsard A, Perrot A, Hulin C, Faure G, Latger-Cannard V, Perrin J.

Blood Cells Mol Dis. 2017 Jul;66:47-49. doi: 10.1016/j.bcmd.2017.08.011. Epub 2017 Aug 9. No abstract available.


Systemic sclerosis

Legendre P, Mouthon L.

Rev Prat. 2017 Sep;67(7):775-783. French.


A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation-Brief Report.

Aymé G, Adam F, Legendre P, Bazaa A, Proulle V, Denis CV, Christophe OD, Lenting PJ.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1736-1740. doi: 10.1161/ATVBAHA.117.309319. Epub 2017 Jun 22.


Age-specific function of α5β1 integrin in microglial migration during early colonization of the developing mouse cortex.

Smolders SM, Swinnen N, Kessels S, Arnauts K, Smolders S, Le Bras B, Rigo JM, Legendre P, Brône B.

Glia. 2017 Jul;65(7):1072-1088. doi: 10.1002/glia.23145. Epub 2017 Apr 18.


Astronomical and atmospheric impacts on deep-sea hydrothermal vent invertebrates.

Lelièvre Y, Legendre P, Matabos M, Mihály S, Lee RW, Sarradin PM, Arango CP, Sarrazin J.

Proc Biol Sci. 2017 Apr 12;284(1852). pii: 20162123. doi: 10.1098/rspb.2016.2123.


Human and natural controls of the variation in aboveground tree biomass in African dry tropical forests.

Pelletier J, Siampale A, Legendre P, Jantz P, Laporte NT, Goetz SJ.

Ecol Appl. 2017 Jul;27(5):1578-1593. doi: 10.1002/eap.1550. Epub 2017 Jun 12.


Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions.

Muczynski V, Aymé G, Regnault V, Vasse M, Borgel D, Legendre P, Bazaa A, Harel A, Loubière C, Lenting PJ, Denis CV, Christophe OD.

Blood. 2017 Apr 27;129(17):2443-2454. doi: 10.1182/blood-2016-06-724351. Epub 2017 Feb 17.


Molecular screening of xerophilic Aspergillus strains producing mycophenolic acid.

Mouhamadou B, Sage L, Périgon S, Séguin V, Bouchart V, Legendre P, Caillat M, Yamouni H, Garon D.

Fungal Biol. 2017 Feb;121(2):103-111. doi: 10.1016/j.funbio.2016.10.001. Epub 2016 Oct 28.


Assessment of multi-contaminant exposure in a cancer treatment center: a 2-year monitoring of molds, mycotoxins, endotoxins, and glucans in bioaerosols.

Heutte N, André V, Dubos Arvis C, Bouchart V, Lemarié F, Legendre P, Votier E, Louis MY, Madelaine S, Séguin V, Gente S, Vérité P, Garon D.

Environ Monit Assess. 2017 Jan;189(1):31. doi: 10.1007/s10661-016-5751-z. Epub 2016 Dec 23.


Anti-endothelial cell antibodies in vasculitis: A systematic review.

Legendre P, Régent A, Thiebault M, Mouthon L.

Autoimmun Rev. 2017 Feb;16(2):146-153. doi: 10.1016/j.autrev.2016.12.012. Epub 2016 Dec 15. Review.


The Willow Microbiome Is Influenced by Soil Petroleum-Hydrocarbon Concentration with Plant Compartment-Specific Effects.

Tardif S, Yergeau É, Tremblay J, Legendre P, Whyte LG, Greer CW.

Front Microbiol. 2016 Sep 8;7:1363. doi: 10.3389/fmicb.2016.01363. eCollection 2016.


Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement.

Van Belle E, Rauch A, Vincent F, Robin E, Kibler M, Labreuche J, Jeanpierre E, Levade M, Hurt C, Rousse N, Dally JB, Debry N, Dallongeville J, Vincentelli A, Delhaye C, Auffray JL, Juthier F, Schurtz G, Lemesle G, Caspar T, Morel O, Dumonteil N, Duhamel A, Paris C, Dupont-Prado A, Legendre P, Mouquet F, Marchant B, Hermoire S, Corseaux D, Moussa K, Manchuelle A, Bauchart JJ, Loobuyck V, Caron C, Zawadzki C, Leroy F, Bodart JC, Staels B, Goudemand J, Lenting PJ, Susen S.

N Engl J Med. 2016 Jul 28;375(4):335-44. doi: 10.1056/NEJMoa1505643.


Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes.

Sándor K, Pallai A, Duró E, Legendre P, Couillin I, Sághy T, Szondy Z.

Amino Acids. 2017 Mar;49(3):671-681. doi: 10.1007/s00726-016-2257-5. Epub 2016 May 28.


A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation.

Adam F, Casari C, Prévost N, Kauskot A, Loubière C, Legendre P, Repérant C, Baruch D, Rosa JP, Bryckaert M, de Groot PG, Christophe OD, Lenting PJ, Denis CV.

Sci Rep. 2016 May 23;6:26306. doi: 10.1038/srep26306.


Clostridium difficile associated reactive arthritis: Case report and literature review.

Legendre P, Lalande V, Eckert C, Barbut F, Fardet L, Meynard JL, Surgers L.

Anaerobe. 2016 Apr;38:76-80. doi: 10.1016/j.anaerobe.2015.12.011. Epub 2015 Dec 30. Review.


Apoptotic Platelet Events Are Not Observed in Severe von Willebrand Disease-Type 2B Mutation p.V1316M.

Berrou E, Kauskot A, Adam F, Harel A, Legendre P, Lavenu Bombled C, Rothschild C, Prevost N, Christophe OD, Lenting PJ, Denis CV, Rosa JP, Bryckaert M.

PLoS One. 2015 Dec 8;10(12):e0143896. doi: 10.1371/journal.pone.0143896. eCollection 2015.


Understanding the Spatio-Temporal Response of Coral Reef Fish Communities to Natural Disturbances: Insights from Beta-Diversity Decomposition.

Lamy T, Legendre P, Chancerelle Y, Siu G, Claudet J.

PLoS One. 2015 Sep 22;10(9):e0138696. doi: 10.1371/journal.pone.0138696. eCollection 2015.


Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism.

Pilorge M, Fassier C, Le Corronc H, Potey A, Bai J, De Gois S, Delaby E, Assouline B, Guinchat V, Devillard F, Delorme R, Nygren G, Råstam M, Meier JC, Otani S, Cheval H, James VM, Topf M, Dear TN, Gillberg C, Leboyer M, Giros B, Gautron S, Hazan J, Harvey RJ, Legendre P, Betancur C.

Mol Psychiatry. 2016 Jul;21(7):936-45. doi: 10.1038/mp.2015.139. Epub 2015 Sep 15.


Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo.

Smolders S, Smolders SM, Swinnen N, Gärtner A, Rigo JM, Legendre P, Brône B.

Front Cell Neurosci. 2015 Aug 5;9:301. doi: 10.3389/fncel.2015.00301. eCollection 2015.


Thirty-year recovery of mollusc communities after nuclear experimentations on Fangataufa atoll (Tuamotu, French Polynesia).

Legendre P, Salvat B.

Proc Biol Sci. 2015 Jul 7;282(1810). pii: 20150750. doi: 10.1098/rspb.2015.0750.


Shear stress-independent binding of von Willebrand factor-type 2B mutants p.R1306Q & p.V1316M to LRP1 explains their increased clearance.

Wohner N, Legendre P, Casari C, Christophe OD, Lenting PJ, Denis CV.

J Thromb Haemost. 2015 May;13(5):815-20. doi: 10.1111/jth.12885. Epub 2015 Mar 31.


Von Willebrand factor as a biological sensor of blood flow to monitor percutaneous aortic valve interventions.

Van Belle E, Rauch A, Vincentelli A, Jeanpierre E, Legendre P, Juthier F, Hurt C, Banfi C, Rousse N, Godier A, Caron C, Elkalioubie A, Corseaux D, Dupont A, Zawadzki C, Delhaye C, Mouquet F, Schurtz G, Deplanque D, Chinetti G, Staels B, Goudemand J, Jude B, Lenting PJ, Susen S.

Circ Res. 2015 Mar 27;116(7):1193-201. doi: 10.1161/CIRCRESAHA.116.305046. Epub 2015 Feb 10.


[Pulmonary arterial hypertension associated with connective tissue diseases].

Legendre P, Mouthon L.

Presse Med. 2014 Sep;43(9):957-69. doi: 10.1016/j.lpm.2014.07.009. Epub 2014 Aug 14. Review. French.


Antibody-based prevention of von Willebrand factor degradation mediated by circulatory assist devices.

Rauch A, Legendre P, Christophe OD, Goudemand J, van Belle E, Vincentelli A, Denis CV, Susen S, Lenting PJ.

Thromb Haemost. 2014 Nov;112(5):1014-23. doi: 10.1160/TH14-02-0148. Epub 2014 Jul 17.


Using phylogenetic information and chemical properties to predict species tolerances to pesticides.

Guénard G, Carsten von der Ohe P, Carlisle Walker S, Lek S, Legendre P.

Proc Biol Sci. 2014 Aug 22;281(1789):20133239. doi: 10.1098/rspb.2013.3239.


Oxidative stress modulates the expression of genes involved in cell survival in ΔF508 cystic fibrosis airway epithelial cells.

Voisin G, Bouvet GF, Legendre P, Dagenais A, Massé C, Berthiaume Y.

Physiol Genomics. 2014 Sep 1;46(17):634-46. doi: 10.1152/physiolgenomics.00003.2014. Epub 2014 Jun 3.


Rhythms and community dynamics of a hydrothermal tubeworm assemblage at main endeavour field - a multidisciplinary deep-sea observatory approach.

Cuvelier D, Legendre P, Laes A, Sarradin PM, Sarrazin J.

PLoS One. 2014 May 8;9(5):e96924. doi: 10.1371/journal.pone.0096924. eCollection 2014.


Acetylcholine controls GABA-, glutamate-, and glycine-dependent giant depolarizing potentials that govern spontaneous motoneuron activity at the onset of synaptogenesis in the mouse embryonic spinal cord.

Czarnecki A, Le Corronc H, Rigato C, Le Bras B, Couraud F, Scain AL, Allain AE, Mouffle C, Bullier E, Mangin JM, Branchereau P, Legendre P.

J Neurosci. 2014 Apr 30;34(18):6389-404. doi: 10.1523/JNEUROSCI.2664-13.2014.


[Microglial cells and development of the embryonic central nervous system].

Legendre P, Le Corronc H.

Med Sci (Paris). 2014 Feb;30(2):147-52. doi: 10.1051/medsci/20143002011. Epub 2014 Feb 24. Review. French.


Statistical methods for temporal and space-time analysis of community composition data.

Legendre P, Gauthier O.

Proc Biol Sci. 2014 Jan 15;281(1778):20132728. doi: 10.1098/rspb.2013.2728. Print 2014 Mar 7. Review.


The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation.

Peigne V, Azoulay E, Coquet I, Mariotte E, Darmon M, Legendre P, Adoui N, Marfaing-Koka A, Wolf M, Schlemmer B, Veyradier A.

Crit Care. 2013 Nov 18;17(6):R273. doi: 10.1186/cc13115.


Genetic structure of the white-footed mouse in the context of the emergence of Lyme disease in southern Québec.

Rogic A, Tessier N, Legendre P, Lapointe FJ, Millien V.

Ecol Evol. 2013 Jul;3(7):2075-88. doi: 10.1002/ece3.620. Epub 2013 Jun 3.


Beta diversity as the variance of community data: dissimilarity coefficients and partitioning.

Legendre P, De Cáceres M.

Ecol Lett. 2013 Aug;16(8):951-63. doi: 10.1111/ele.12141. Epub 2013 Jul 1.


In vivo assembly of the axon initial segment in motor neurons.

Le Bras B, Fréal A, Czarnecki A, Legendre P, Bullier E, Komada M, Brophy PJ, Davenne M, Couraud F.

Brain Struct Funct. 2014 Jul;219(4):1433-50. doi: 10.1007/s00429-013-0578-7. Epub 2013 Jun 2.


Vesicular storage of glycine in glutamatergic terminals in mouse hippocampus.

Muller E, Bakkar W, Martina M, Sokolovski A, Wong AY, Legendre P, Bergeron R.

Neuroscience. 2013 Jul 9;242:110-27. doi: 10.1016/j.neuroscience.2013.03.007. Epub 2013 Mar 16.


Potential changes in forest composition could reduce impacts of climate change on boreal wildfires.

Terrier A, Girardin MP, Périé C, Legendre P, Bergeron Y.

Ecol Appl. 2013 Jan;23(1):21-35.


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