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Items: 10

1.

Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam.

Nukaga M, Papp-Wallace KM, Hoshino T, Lefurgy ST, Bethel CR, Barnes MD, Zeiser ET, Johnson JK, Bonomo RA.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02371-17. doi: 10.1128/AAC.02371-17. Print 2018 May.

2.

A 13-week research-based biochemistry laboratory curriculum.

Lefurgy ST, Mundorff EC.

Biochem Mol Biol Educ. 2017 Sep;45(5):437-448. doi: 10.1002/bmb.21054. Epub 2017 Mar 2.

3.

Analysis of the Structure and Function of FOX-4 Cephamycinase.

Lefurgy ST, Malashkevich VN, Aguilan JT, Nieves E, Mundorff EC, Biju B, Noel MA, Toro R, Baiwir D, Papp-Wallace KM, Almo SC, Frere JM, Bou G, Bonomo RA.

Antimicrob Agents Chemother. 2015 Nov 2;60(2):717-28. doi: 10.1128/AAC.01887-15. Print 2016 Feb.

4.

Alteration of substrate specificity of alanine dehydrogenase.

Fernandes P, Aldeborgh H, Carlucci L, Walsh L, Wasserman J, Zhou E, Lefurgy ST, Mundorff EC.

Protein Eng Des Sel. 2015 Feb;28(2):29-35. doi: 10.1093/protein/gzu053. Epub 2014 Dec 23.

5.

Structural analysis of the Asn152Gly mutant of P99 cephalosporinase.

Ruble JF, Lefurgy ST, Cornish VW, Powers RA.

Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1189-93. doi: 10.1107/S0907444912024080. Epub 2012 Aug 18.

PMID:
22948919
6.

Analytical expressions for the homotropic binding of ligand to protein dimers and trimers.

Lefurgy ST, Leyh TS.

Anal Biochem. 2012 Feb 15;421(2):433-8. doi: 10.1016/j.ab.2011.12.016. Epub 2011 Dec 16.

7.

Probing ligand-binding pockets of the mevalonate pathway enzymes from Streptococcus pneumoniae.

Lefurgy ST, Rodriguez SB, Park CS, Cahill S, Silverman RB, Leyh TS.

J Biol Chem. 2010 Jul 2;285(27):20654-63. doi: 10.1074/jbc.M109.098350. Epub 2010 Apr 19.

8.

Mevalonate analogues as substrates of enzymes in the isoprenoid biosynthetic pathway of Streptococcus pneumoniae.

Kudoh T, Park CS, Lefurgy ST, Sun M, Michels T, Leyh TS, Silverman RB.

Bioorg Med Chem. 2010 Feb;18(3):1124-34. doi: 10.1016/j.bmc.2009.12.050. Epub 2009 Dec 24.

9.

Saturation mutagenesis of Asn152 reveals a substrate selectivity switch in P99 cephalosporinase.

Lefurgy ST, de Jong RM, Cornish VW.

Protein Sci. 2007 Dec;16(12):2636-46.

10.

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