1.

Studying β1 and β2 adrenergic receptor signals in cardiac cells using FRET-based sensors.

Grisan F, Burdyga A, Iannucci LF, Surdo NC, Pozzan T, Di Benedetto G, Lefkimmiatis K.

Prog Biophys Mol Biol. 2019 Jun 29. pii: S0079-6107(19)30060-4. doi: 10.1016/j.pbiomolbio.2019.06.001. [Epub ahead of print]

PMID:
31266653
2.

Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane.

Burdyga A, Surdo NC, Monterisi S, Di Benedetto G, Grisan F, Penna E, Pellegrini L, Zaccolo M, Bortolozzi M, Swietach P, Pozzan T, Lefkimmiatis K.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6497-E6506. doi: 10.1073/pnas.1806318115. Epub 2018 Jun 25. Erratum in: Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7882.

3.

Shaping mitochondrial dynamics: The role of cAMP signalling.

Di Benedetto G, Gerbino A, Lefkimmiatis K.

Biochem Biophys Res Commun. 2018 May 27;500(1):65-74. doi: 10.1016/j.bbrc.2017.05.041. Epub 2017 May 10. Review.

PMID:
28501614
4.

Beyond Intracellular Signaling: The Ins and Outs of Second Messengers Microdomains.

Filadi R, Basso E, Lefkimmiatis K, Pozzan T.

Adv Exp Med Biol. 2017;981:279-322. doi: 10.1007/978-3-319-55858-5_12. Review.

PMID:
29594866
5.

Exploring cells with targeted biosensors.

Pendin D, Greotti E, Lefkimmiatis K, Pozzan T.

J Gen Physiol. 2017 Jan;149(1):1-36. doi: 10.1085/jgp.201611654. Epub 2016 Dec 27. Review.

6.

Sympathetic neurons are a powerful driver of myocyte function in cardiovascular disease.

Larsen HE, Lefkimmiatis K, Paterson DJ.

Sci Rep. 2016 Dec 14;6:38898. doi: 10.1038/srep38898.

7.

Dysregulation of Neuronal Ca2+ Channel Linked to Heightened Sympathetic Phenotype in Prohypertensive States.

Larsen HE, Bardsley EN, Lefkimmiatis K, Paterson DJ.

J Neurosci. 2016 Aug 17;36(33):8562-73. doi: 10.1523/JNEUROSCI.1059-16.2016.

8.

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes.

Richards M, Lomas O, Jalink K, Ford KL, Vaughan-Jones RD, Lefkimmiatis K, Swietach P.

Cardiovasc Res. 2016 Jun 1;110(3):395-407. doi: 10.1093/cvr/cvw080. Epub 2016 Apr 18.

9.

Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.

Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M.

Circ Res. 2015 Sep 25;117(8):707-19. doi: 10.1161/CIRCRESAHA.114.305892. Epub 2015 Aug 4.

PMID:
26243800
10.

Simultaneous assessment of cAMP signaling events in different cellular compartments using FRET-based reporters.

Burdyga A, Lefkimmiatis K.

Methods Mol Biol. 2015;1294:1-12. doi: 10.1007/978-1-4939-2537-7_1.

PMID:
25783873
11.

Protein kinase inhibitor β enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.

Kovacs Z, Schacht T, Herrmann AK, Albrecht P, Lefkimmiatis K, Methner A.

Biochem J. 2014 Aug 15;462(1):125-32. doi: 10.1042/BJ20131198.

PMID:
24869658
12.

cAMP signaling in subcellular compartments.

Lefkimmiatis K, Zaccolo M.

Pharmacol Ther. 2014 Sep;143(3):295-304. doi: 10.1016/j.pharmthera.2014.03.008. Epub 2014 Apr 1. Review.

13.

cAMP signalling meets mitochondrial compartments.

Lefkimmiatis K.

Biochem Soc Trans. 2014 Apr;42(2):265-9. doi: 10.1042/BST20130281. Review. Erratum in: Biochem Soc Trans. 2014 Aug;42(4):1261.

PMID:
24646228
14.

The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics.

Lefkimmiatis K, Leronni D, Hofer AM.

J Cell Biol. 2013 Aug 5;202(3):453-62. doi: 10.1083/jcb.201303159. Epub 2013 Jul 29.

15.

Termination and activation of store-operated cyclic AMP production.

Maiellaro I, Lefkimmiatis K, Moyer MP, Curci S, Hofer AM.

J Cell Mol Med. 2012 Nov;16(11):2715-25. doi: 10.1111/j.1582-4934.2012.01592.x.

16.

The {omega}-3 fatty acid eicosapentaenoic acid elicits cAMP generation in colonic epithelial cells via a "store-operated" mechanism.

Roy J, Lefkimmiatis K, Moyer MP, Curci S, Hofer AM.

Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G715-22. doi: 10.1152/ajpgi.00028.2010. Epub 2010 Jun 24.

17.

The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome.

Driscoll JJ, Pelluru D, Lefkimmiatis K, Fulciniti M, Prabhala RH, Greipp PR, Barlogie B, Tai YT, Anderson KC, Shaughnessy JD Jr, Annunziata CM, Munshi NC.

Blood. 2010 Apr 8;115(14):2827-34. doi: 10.1182/blood-2009-03-211045. Epub 2009 Nov 30.

18.

"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate.

Lefkimmiatis K, Moyer MP, Curci S, Hofer AM.

PLoS One. 2009 Nov 3;4(11):e7649. doi: 10.1371/journal.pone.0007649.

19.

p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes.

Lefkimmiatis K, Caratozzolo MF, Merlo P, D'Erchia AM, Navarro B, Levrero M, Sbisa' E, Tullo A.

Cancer Res. 2009 Nov 15;69(22):8563-71. doi: 10.1158/0008-5472.CAN-09-0259. Epub 2009 Oct 27.

20.

Store-operated cyclic AMP signalling mediated by STIM1.

Lefkimmiatis K, Srikanthan M, Maiellaro I, Moyer MP, Curci S, Hofer AM.

Nat Cell Biol. 2009 Apr;11(4):433-42. doi: 10.1038/ncb1850. Epub 2009 Mar 15.

PMID:
19287379
21.

Extracellular calcium and cAMP: second messengers as "third messengers"?

Hofer AM, Lefkimmiatis K.

Physiology (Bethesda). 2007 Oct;22:320-7. Review.

22.

Phylogenetic analyses of complete mitochondrial genome sequences suggest a basal divergence of the enigmatic rodent Anomalurus.

Horner DS, Lefkimmiatis K, Reyes A, Gissi C, Saccone C, Pesole G.

BMC Evol Biol. 2007 Feb 8;7:16.

23.

The fatty acid synthase gene is a conserved p53 family target from worm to human.

D'Erchia AM, Tullo A, Lefkimmiatis K, Saccone C, Sbisà E.

Cell Cycle. 2006 Apr;5(7):750-8. Epub 2006 Apr 1.

PMID:
16582625
24.

Connecting p63 to cellular proliferation: the example of the adenosine deaminase target gene.

Sbisà E, Mastropasqua G, Lefkimmiatis K, Caratozzolo MF, D'Erchia AM, Tullo A.

Cell Cycle. 2006 Jan;5(2):205-12. Epub 2006 Jan 16.

PMID:
16410722

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