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Predicting language outcomes after stroke: Is structural disconnection a useful predictor?

Hope TMH, Leff AP, Price CJ.

Neuroimage Clin. 2018 Mar 30;19:22-29. doi: 10.1016/j.nicl.2018.03.037. eCollection 2018.


Patients with a severe prolonged Disorder of Consciousness can show classical EEG responses to their own name compared with others' names.

Kempny AM, James L, Yelden K, Duport S, Farmer SF, Diane Playford E, Leff AP.

Neuroimage Clin. 2018 Apr 30;19:311-319. doi: 10.1016/j.nicl.2018.04.027. eCollection 2018.


Dorsal and ventral visual stream contributions to preserved reading ability in patients with central alexia.

Aguilar OM, Kerry SJ, Crinion JT, Callaghan MF, Woodhead ZVJ, Leff AP.

Cortex. 2018 Sep;106:200-212. doi: 10.1016/j.cortex.2018.06.003. Epub 2018 Jun 23.


Variational Bayesian inversion for hierarchical unsupervised generative embedding (HUGE).

Yao Y, Raman SS, Schiek M, Leff A, Frässle S, Stephan KE.

Neuroimage. 2018 Oct 1;179:604-619. doi: 10.1016/j.neuroimage.2018.06.073. Epub 2018 Jun 28.


Randomized trial of iReadMore word reading training and brain stimulation in central alexia.

Woodhead ZVJ, Kerry SJ, Aguilar OM, Ong YH, Hogan JS, Pappa K, Leff AP, Crinion JT.

Brain. 2018 Jul 1;141(7):2127-2141. doi: 10.1093/brain/awy138.


A generative model of whole-brain effective connectivity.

Frässle S, Lomakina EI, Kasper L, Manjaly ZM, Leff A, Pruessmann KP, Buhmann JM, Stephan KE.

Neuroimage. 2018 Oct 1;179:505-529. doi: 10.1016/j.neuroimage.2018.05.058. Epub 2018 May 25.


Lesion-site-dependent responses to therapy after aphasic stroke.

Aguilar OM, Kerry SJ, Ong YH, Callaghan MF, Crinion J, Woodhead ZVJ, Price CJ, Leff AP, Hope TMH.

J Neurol Neurosurg Psychiatry. 2018 Apr 17. pii: jnnp-2017-317446. doi: 10.1136/jnnp-2017-317446. [Epub ahead of print] No abstract available.


The impact of sample size on the reproducibility of voxel-based lesion-deficit mappings.

Lorca-Puls DL, Gajardo-Vidal A, White J, Seghier ML, Leff AP, Green DW, Crinion JT, Ludersdorfer P, Hope TMH, Bowman H, Price CJ.

Neuropsychologia. 2018 Jul 1;115:101-111. doi: 10.1016/j.neuropsychologia.2018.03.014. Epub 2018 Mar 15.


How distributed processing produces false negatives in voxel-based lesion-deficit analyses.

Gajardo-Vidal A, Lorca-Puls DL, Crinion JT, White J, Seghier ML, Leff AP, Hope TMH, Ludersdorfer P, Green DW, Bowman H, Price CJ.

Neuropsychologia. 2018 Jul 1;115:124-133. doi: 10.1016/j.neuropsychologia.2018.02.025. Epub 2018 Mar 2.


Randomised, double-blind, placebo-controlled crossover study of single-dose guanfacine in unilateral neglect following stroke.

Dalmaijer ES, Li KMS, Gorgoraptis N, Leff AP, Cohen DL, Parton AD, Husain M, Malhotra PA.

J Neurol Neurosurg Psychiatry. 2018 Jun;89(6):593-598. doi: 10.1136/jnnp-2017-317338. Epub 2018 Feb 7.


Biomarkers of Stroke Recovery: Consensus-Based Core Recommendations from the Stroke Recovery and Rehabilitation Roundtable.

Boyd LA, Hayward KS, Ward NS, Stinear CM, Rosso C, Fisher RJ, Carter AR, Leff AP, Copland DA, Carey LM, Cohen LG, Basso DM, Maguire JM, Cramer SC.

Neurorehabil Neural Repair. 2017 Oct-Nov;31(10-11):864-876. doi: 10.1177/1545968317732680. Review.


Less is more: neural mechanisms underlying anomia treatment in chronic aphasic patients.

Nardo D, Holland R, Leff AP, Price CJ, Crinion JT.

Brain. 2017 Nov 1;140(11):3039-3054. doi: 10.1093/brain/awx234. No abstract available.


Direct Detection Electron Energy-Loss Spectroscopy: A Method to Push the Limits of Resolution and Sensitivity.

Hart JL, Lang AC, Leff AC, Longo P, Trevor C, Twesten RD, Taheri ML.

Sci Rep. 2017 Aug 15;7(1):8243. doi: 10.1038/s41598-017-07709-4.


Biomarkers of stroke recovery: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable.

Boyd LA, Hayward KS, Ward NS, Stinear CM, Rosso C, Fisher RJ, Carter AR, Leff AP, Copland DA, Carey LM, Cohen LG, Basso DM, Maguire JM, Cramer SC.

Int J Stroke. 2017 Jul;12(5):480-493. doi: 10.1177/1747493017714176.


Late recovery of awareness in prolonged disorders of consciousness -a cross-sectional cohort study.

Yelden K, Duport S, James LM, Kempny A, Farmer SF, Leff AP, Playford ED.

Disabil Rehabil. 2018 Oct;40(20):2433-2438. doi: 10.1080/09638288.2017.1339209. Epub 2017 Jun 21.


Direct Observation of Sink-Dependent Defect Evolution in Nanocrystalline Iron under Irradiation.

El-Atwani O, Nathaniel JE, Leff AC, Hattar K, Taheri ML.

Sci Rep. 2017 May 12;7(1):1836. doi: 10.1038/s41598-017-01744-x.


Right hemisphere structural adaptation and changing language skills years after left hemisphere stroke.

Hope TMH, Leff AP, Prejawa S, Bruce R, Haigh Z, Lim L, Ramsden S, Oberhuber M, Ludersdorfer P, Crinion J, Seghier ML, Price CJ.

Brain. 2017 Jun 1;140(6):1718-1728. doi: 10.1093/brain/awx086.


Using transcranial magnetic stimulation of the undamaged brain to identify lesion sites that predict language outcome after stroke.

Lorca-Puls DL, Gajardo-Vidal A, Seghier ML, Leff AP, Sethi V, Prejawa S, Hope TMH, Devlin JT, Price CJ.

Brain. 2017 Jun 1;140(6):1729-1742. doi: 10.1093/brain/awx087.


Auditory training changes temporal lobe connectivity in 'Wernicke's aphasia': a randomised trial.

Woodhead ZV, Crinion J, Teki S, Penny W, Price CJ, Leff AP.

J Neurol Neurosurg Psychiatry. 2017 Jul;88(7):586-594. doi: 10.1136/jnnp-2016-314621. Epub 2017 Mar 4.


Functional near infrared spectroscopy as a probe of brain function in people with prolonged disorders of consciousness.

Kempny AM, James L, Yelden K, Duport S, Farmer S, Playford ED, Leff AP.

Neuroimage Clin. 2016 Jul 27;12:312-9. doi: 10.1016/j.nicl.2016.07.013. eCollection 2016.


Modulation of frontal effective connectivity during speech.

Holland R, Leff AP, Penny WD, Rothwell JC, Crinion J.

Neuroimage. 2016 Oct 15;140:126-33. doi: 10.1016/j.neuroimage.2016.01.037. Epub 2016 Jan 26.


Distinguishing the effect of lesion load from tract disconnection in the arcuate and uncinate fasciculi.

Hope TMH, Seghier ML, Prejawa S, Leff AP, Price CJ.

Neuroimage. 2016 Jan 15;125:1169-1173. doi: 10.1016/j.neuroimage.2015.09.025. Epub 2015 Sep 21.


Facilitating text reading in posterior cortical atrophy.

Yong KX, Rajdev K, Shakespeare TJ, Leff AP, Crutch SJ.

Neurology. 2015 Jul 28;85(4):339-48. doi: 10.1212/WNL.0000000000001782. Epub 2015 Jul 2.


Using functional imaging to understand therapeutic effects in poststroke aphasia.

Crinion JT, Leff AP.

Curr Opin Neurol. 2015 Aug;28(4):330-7. doi: 10.1097/WCO.0000000000000217. Review.


Tatsuji Inouye (1881-1976).

Leff AP.

J Neurol. 2015 Oct;262(10):2399-400. doi: 10.1007/s00415-015-7801-9. Epub 2015 Jun 6. No abstract available.


The PLORAS Database: A data repository for Predicting Language Outcome and Recovery After Stroke.

Seghier ML, Patel E, Prejawa S, Ramsden S, Selmer A, Lim L, Browne R, Rae J, Haigh Z, Ezekiel D, Hope TM, Leff AP, Price CJ.

Neuroimage. 2016 Jan 1;124(Pt B):1208-12. doi: 10.1016/j.neuroimage.2015.03.083. Epub 2015 Apr 14.


A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest.

Li J, Wang H, Zhong Q, Zhu X, Chen SJ, Qian Y, Costakis J, Bunney G, Beiser DG, Leff AR, Lewandowski ED, ÓDonnell JM, Vanden Hoek TL.

Am J Physiol Heart Circ Physiol. 2015 Jun 1;308(11):H1414-22. doi: 10.1152/ajpheart.00748.2014. Epub 2015 Mar 20.


Dynamic causal modelling for functional near-infrared spectroscopy.

Tak S, Kempny AM, Friston KJ, Leff AP, Penny WD.

Neuroimage. 2015 May 1;111:338-49. doi: 10.1016/j.neuroimage.2015.02.035. Epub 2015 Feb 25.


Cross-language differences in the brain network subserving intelligible speech.

Ge J, Peng G, Lyu B, Wang Y, Zhuo Y, Niu Z, Tan LH, Leff AP, Gao JH.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):2972-7. doi: 10.1073/pnas.1416000112. Epub 2015 Feb 23.


Estimation of dislocation density from precession electron diffraction data using the Nye tensor.

Leff AC, Weinberger CR, Taheri ML.

Ultramicroscopy. 2015 Jun;153:9-21. doi: 10.1016/j.ultramic.2015.02.002. Epub 2015 Feb 10.


Comparing language outcomes in monolingual and bilingual stroke patients.

Hope TM, Parker Jones ', Grogan A, Crinion J, Rae J, Ruffle L, Leff AP, Seghier ML, Price CJ, Green DW.

Brain. 2015 Apr;138(Pt 4):1070-83. doi: 10.1093/brain/awv020. Epub 2015 Feb 13.


Eye-Search: A web-based therapy that improves visual search in hemianopia.

Ong YH, Jacquin-Courtois S, Gorgoraptis N, Bays PM, Husain M, Leff AP.

Ann Clin Transl Neurol. 2015 Jan;2(1):74-8. doi: 10.1002/acn3.154. Epub 2014 Nov 27.


Avatar therapy for persecutory auditory hallucinations: What is it and how does it work?

Leff J, Williams G, Huckvale M, Arbuthnot M, Leff AP.

Psychosis. 2014 Jun;6(2):166-176. Epub 2013 Mar 4.


Attenuation of lipopolysaccharide-induced lung vascular stiffening by lipoxin reduces lung inflammation.

Meng F, Mambetsariev I, Tian Y, Beckham Y, Meliton A, Leff A, Gardel ML, Allen MJ, Birukov KG, Birukova AA.

Am J Respir Cell Mol Biol. 2015 Feb;52(2):152-61. doi: 10.1165/rcmb.2013-0468OC.


An inability to learn to read caused by shaken baby syndrome.

Bevilacqua L, Kuczynski A, James-Galton M, Leff AP.

BMJ Case Rep. 2014 Apr 28;2014. pii: bcr2013203070. doi: 10.1136/bcr-2013-203070.


TAT-protein blockade during ischemia/reperfusion reveals critical role for p85 PI3K-PTEN interaction in cardiomyocyte injury.

Zhu X, Shao ZH, Li C, Li J, Zhong Q, Learoyd J, Meliton A, Meliton L, Leff AR, Vanden Hoek TL.

PLoS One. 2014 Apr 21;9(4):e95622. doi: 10.1371/journal.pone.0095622. eCollection 2014.


Between thought and expression, a magnetoencephalography study of the "tip-of-the-tongue" phenomenon.

Resnik K, Bradbury D, Barnes GR, Leff AP.

J Cogn Neurosci. 2014 Oct;26(10):2210-23. doi: 10.1162/jocn_a_00611. Epub 2014 Mar 27.


Sensory-to-motor integration during auditory repetition: a combined fMRI and lesion study.

Parker Jones ', Prejawa S, Hope TM, Oberhuber M, Seghier ML, Leff AP, Green DW, Price CJ.

Front Hum Neurosci. 2014 Jan 31;8:24. doi: 10.3389/fnhum.2014.00024. eCollection 2014.


Gradual lesion expansion and brain shrinkage years after stroke.

Seghier ML, Ramsden S, Lim L, Leff AP, Price CJ.

Stroke. 2014 Mar;45(3):877-9. doi: 10.1161/STROKEAHA.113.003587. Epub 2014 Jan 14.


Automated identification of brain tumors from single MR images based on segmentation with refined patient-specific priors.

Sanjuán A, Price CJ, Mancini L, Josse G, Grogan A, Yamamoto AK, Geva S, Leff AP, Yousry TA, Seghier ML.

Front Neurosci. 2013 Dec 17;7:241. doi: 10.3389/fnins.2013.00241. eCollection 2013.


Predicting outcome and recovery after stroke with lesions extracted from MRI images.

Hope TM, Seghier ML, Leff AP, Price CJ.

Neuroimage Clin. 2013 Mar 22;2:424-33. doi: 10.1016/j.nicl.2013.03.005. eCollection 2013.


Reading therapy strengthens top-down connectivity in patients with pure alexia.

Woodhead ZV, Penny W, Barnes GR, Crewes H, Wise RJ, Price CJ, Leff AP.

Brain. 2013 Aug;136(Pt 8):2579-91. doi: 10.1093/brain/awt186.


The right hemisphere supports but does not replace left hemisphere auditory function in patients with persisting aphasia.

Teki S, Barnes GR, Penny WD, Iverson P, Woodhead ZV, Griffiths TD, Leff AP.

Brain. 2013 Jun;136(Pt 6):1901-12. doi: 10.1093/brain/awt087. Epub 2013 May 28.


Sight and sound out of synch: fragmentation and renormalisation of audiovisual integration and subjective timing.

Freeman ED, Ipser A, Palmbaha A, Paunoiu D, Brown P, Lambert C, Leff A, Driver J.

Cortex. 2013 Nov-Dec;49(10):2875-87. doi: 10.1016/j.cortex.2013.03.006. Epub 2013 Apr 1.


Can fully automated detection of corticospinal tract damage be used in stroke patients?

Kou N, Park CH, Seghier ML, Leff AP, Ward NS.

Neurology. 2013 Jun 11;80(24):2242-5. doi: 10.1212/WNL.0b013e318296e977. Epub 2013 May 8.


Cognitive control and the salience network: an investigation of error processing and effective connectivity.

Ham T, Leff A, de Boissezon X, Joffe A, Sharp DJ.

J Neurosci. 2013 Apr 17;33(16):7091-8. doi: 10.1523/JNEUROSCI.4692-12.2013.


Mechanical induction of group V phospholipase A(2) causes lung inflammation and acute lung injury.

Meliton AY, Muñoz NM, Meliton LN, Birukova AA, Leff AR, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2013 May 15;304(10):L689-700. doi: 10.1152/ajplung.00047.2013. Epub 2013 Mar 22.


Computer-assisted therapy for medication-resistant auditory hallucinations: proof-of-concept study.

Leff J, Williams G, Huckvale MA, Arbuthnot M, Leff AP.

Br J Psychiatry. 2013 Jun;202:428-33. doi: 10.1192/bjp.bp.112.124883. Epub 2013 Feb 21. Erratum in: Br J Psychiatry. 2013 Oct;203:313.


Auditory-motor interactions for the production of native and non-native speech.

Parker Jones O, Seghier ML, Kawabata Duncan KJ, Leff AP, Green DW, Price CJ.

J Neurosci. 2013 Feb 6;33(6):2376-87. doi: 10.1523/JNEUROSCI.3289-12.2013.


Reading front to back: MEG evidence for early feedback effects during word recognition.

Woodhead ZV, Barnes GR, Penny W, Moran R, Teki S, Price CJ, Leff AP.

Cereb Cortex. 2014 Mar;24(3):817-25. doi: 10.1093/cercor/bhs365. Epub 2012 Nov 21.

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