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Effectiveness of Adjunctive Analgesics in Head and Neck Cancer Patients Receiving Curative (Chemo-) Radiotherapy: A Systematic Review.

Lefebvre T, Tack L, Lycke M, Duprez F, Goethals L, Rottey S, Cool L, Van Eygen K, Stubbs B, Schofield P, Pottel H, Boterberg T, Debruyne P.

Pain Med. 2020 Mar 27. pii: pnaa044. doi: 10.1093/pm/pnaa044. [Epub ahead of print]


Female obesity does not impact live birth rate after frozen-thawed blastocyst transfer.

Prost E, Reignier A, Leperlier F, Caillet P, Barrière P, Fréour T, Lefebvre T.

Hum Reprod. 2020 Mar 13. pii: deaa010. doi: 10.1093/humrep/deaa010. [Epub ahead of print]


[Evaluation of a support for the analysis of electrocardiogram by emergency residents].

Viricel G, Martinez M, Lefebvre T, Da Costa A.

Ann Cardiol Angeiol (Paris). 2020 Mar;69(1):24-30. doi: 10.1016/j.ancard.2020.01.007. Epub 2020 Feb 29. French.


Cadmium exposure enhances cell migration and invasion through modulated TRPM7 channel expression.

Vanlaeys A, Fouquet G, Kischel P, Hague F, Pasco-Brassart S, Lefebvre T, Rybarczyk P, Dhennin-Duthille I, Brassart B, Ouadid-Ahidouch H, Gautier M.

Arch Toxicol. 2020 Mar;94(3):735-747. doi: 10.1007/s00204-020-02674-w. Epub 2020 Feb 20.


A hepcidin-based approach for iron therapy in hemodialysis patients: A pilot study.

Touzot M, Lefebvre T, Maheas C, Ridel C, Puy H, Karim Z.

Hemodial Int. 2020 Feb 11. doi: 10.1111/hdi.12823. [Epub ahead of print]


Should artificial shrinkage be performed prior to blastocyst vitrification? A systematic review of the literature and meta-analysis.

Boyard J, Reignier A, Chtourou S, Lefebvre T, Barrière P, Fréour T.

Hum Fertil (Camb). 2020 Jan 24:1-9. doi: 10.1080/14647273.2019.1701205. [Epub ahead of print]


The challenging management of Rift Valley Fever in humans: literature review of the clinical disease and algorithm proposal.

Javelle E, Lesueur A, Pommier de Santi V, de Laval F, Lefebvre T, Holweck G, Durand GA, Leparc-Goffart I, Texier G, Simon F.

Ann Clin Microbiol Antimicrob. 2020 Jan 22;19(1):4. doi: 10.1186/s12941-020-0346-5. Review.


Editorial: O-GlcNAcylation: Expanding the Frontiers.

Issad T, Lefebvre T.

Front Endocrinol (Lausanne). 2019 Dec 13;10:867. doi: 10.3389/fendo.2019.00867. eCollection 2019. No abstract available.


Phlebotomy as an efficient long-term treatment of congenital erythropoietic porphyria.

Mirmiran A, Poli A, Ged C, Schmitt C, Lefebvre T, Manceau H, Daher R, Moulouel B, Peoc'h K, Simonin S, Blouin JM, Deybach JC, Nicolas G, Puy H, Richard E, Gouya L.

Haematologica. 2020 Jan 9. pii: haematol.2019.228270. doi: 10.3324/haematol.2019.228270. [Epub ahead of print] No abstract available.


Evaluation of automatic annotation by a multi-terminological concepts extractor within a corpus of data from family medicine consultations.

Siefridt C, Grosjean J, Lefebvre T, Rollin L, Darmoni S, Schuers M.

Int J Med Inform. 2020 Jan;133:104009. doi: 10.1016/j.ijmedinf.2019.104009. Epub 2019 Nov 1.


Development of an analytical method for chlorophyll pigments separation by reversed-phase supercritical fluid chromatography.

Lefebvre T, Talbi A, Atwi-Ghaddar S, Destandau E, Lesellier E.

J Chromatogr A. 2020 Feb 8;1612:460643. doi: 10.1016/j.chroma.2019.460643. Epub 2019 Oct 21.


Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study.

Tack L, Lefebvre T, Lycke M, Pottel L, Cool L, Ketelaars L, De Zutter J, Martens E, Pottel H, Stellamans K, Van Eygen K, Werbrouck P, Vergauwe P, Wildiers H, Schofield P, Boterberg T, Debruyne PR.

J Geriatr Oncol. 2020 Mar;11(2):320-326. doi: 10.1016/j.jgo.2019.09.003. Epub 2019 Oct 14.


MRI cine-tagging of cardiac-induced motion for noninvasive staging of liver fibrosis.

Lefebvre T, Petitclerc L, Hébert M, Bilodeau L, Sebastiani G, Olivié D, Gao ZH, Sylvestre MP, Cloutier G, Nguyen BN, Gilbert G, Tang A.

J Magn Reson Imaging. 2019 Oct 12. doi: 10.1002/jmri.26935. [Epub ahead of print]


Genetic background influences hepcidin response to iron imbalance in a mouse model of hemolytic anemia (Congenital erythropoietic porphyria).

Lefebvre T, Millot S, Richard E, Blouin JM, Lalanne M, Lamrissi-Garcia I, Costet P, Lyoumi S, Gouya L, Puy H, Moreau-Gaudry F, de Verneuil H, Karim Z, Ged C.

Biochem Biophys Res Commun. 2019 Dec 3;520(2):297-303. doi: 10.1016/j.bbrc.2019.09.141. Epub 2019 Oct 7.


A gelatinous leukemia.

Lefebvre T, Mauvieux L.

Blood. 2019 Aug 29;134(9):785. doi: 10.1182/blood.2019001505. No abstract available.


Performance of Day 5 KIDScore™ morphokinetic prediction models of implantation and live birth after single blastocyst transfer.

Reignier A, Girard JM, Lammers J, Chtourou S, Lefebvre T, Barriere P, Freour T.

J Assist Reprod Genet. 2019 Nov;36(11):2279-2285. doi: 10.1007/s10815-019-01567-x. Epub 2019 Aug 23.


Extrahepatic hepcidin production: The intriguing outcomes of recent years.

Daher R, Lefebvre T, Puy H, Karim Z.

World J Clin Cases. 2019 Aug 6;7(15):1926-1936. doi: 10.12998/wjcc.v7.i15.1926. Review.


OGT Controls the Expression and the Glycosylation of E-cadherin, and Affects Glycosphingolipid Structures in Human Colon Cell Lines.

Biwi J, Clarisse C, Biot C, Kozak RP, Madunic K, Mortuaire M, Wuhrer M, Spencer DIR, Schulz C, Guerardel Y, Lefebvre T, Vercoutter-Edouart AS.

Proteomics. 2019 Nov;19(21-22):e1800452. doi: 10.1002/pmic.201800452. Epub 2019 Aug 20.


A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome.

Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaav5467. doi: 10.1126/scitranslmed.aav5467.


Prospective comparison of transient, point shear wave, and magnetic resonance elastography for staging liver fibrosis.

Lefebvre T, Wartelle-Bladou C, Wong P, Sebastiani G, Giard JM, Castel H, Murphy-Lavallée J, Olivié D, Ilinca A, Sylvestre MP, Gilbert G, Gao ZH, Nguyen BN, Cloutier G, Tang A.

Eur Radiol. 2019 Dec;29(12):6477-6488. doi: 10.1007/s00330-019-06331-4. Epub 2019 Jul 5.


An observational pilot study to evaluate the feasibility and quality of oncological home-hospitalization.

Cool L, Missiaen J, Vandijck D, Lefebvre T, Lycke M, De Jonghe PJ, Vergauwe P, Foulon V, Pottel H, Debruyne P, Van Eygen K.

Eur J Oncol Nurs. 2019 Jun;40:44-52. doi: 10.1016/j.ejon.2019.03.003. Epub 2019 Mar 23.


O-GlcNAcylation Is Involved in the Regulation of Stem Cell Markers Expression in Colon Cancer Cells.

Fuentes-García G, Castañeda-Patlán MC, Vercoutter-Edouart AS, Lefebvre T, Robles-Flores M.

Front Endocrinol (Lausanne). 2019 May 8;10:289. doi: 10.3389/fendo.2019.00289. eCollection 2019.


Replacing Fish Meal with Defatted Insect Meal (Yellow Mealworm Tenebrio molitor) Improves the Growth and Immunity of Pacific White Shrimp (Litopenaeus vannamei).

Motte C, Rios A, Lefebvre T, Do H, Henry M, Jintasataporn O.

Animals (Basel). 2019 May 21;9(5). pii: E258. doi: 10.3390/ani9050258.


Screening Methods for Age-Related Hearing Loss in Older Patients with Cancer: A Review of the Literature.

Lycke M, Lefebvre T, Cool L, Van Eygen K, Boterberg T, Schofield P, Debruyne PR.

Geriatrics (Basel). 2018 Aug 2;3(3). pii: E48. doi: 10.3390/geriatrics3030048. Review.


Shifting specialized oncological care from hospital- to home-setting: is there support among patients, specialists and general practitioners?

Cool L, Brewaeys C, Viaene S, Missiaen J, Lycke M, Lefebvre T, Tack L, Foulon V, Pottel H, Debruyne P, Vandijck D, Van Eygen K.

Acta Clin Belg. 2019 Apr 19:1-8. doi: 10.1080/17843286.2019.1605467. [Epub ahead of print]


Identification of O-Glcnacylated Proteins in Trypanosoma cruzi.

Torres-Gutiérrez E, Pérez-Cervera Y, Camoin L, Zenteno E, Aquino-Gil MO, Lefebvre T, Cabrera-Bravo M, Reynoso-Ducoing O, Bucio-Torres MI, Salazar-Schettino PM.

Front Endocrinol (Lausanne). 2019 Mar 29;10:199. doi: 10.3389/fendo.2019.00199. eCollection 2019.


[So far, so close: the History of Pharmacy Society and the French History of Medicine Society].

Lefebvre T.

Rev Prat. 2019 Mar;69(3):344-346. French. No abstract available.


Ion Channels: New Actors Playing in Chemotherapeutic Resistance.

Kischel P, Girault A, Rodat-Despoix L, Chamlali M, Radoslavova S, Abou Daya H, Lefebvre T, Foulon A, Rybarczyk P, Hague F, Dhennin-Duthille I, Gautier M, Ouadid-Ahidouch H.

Cancers (Basel). 2019 Mar 16;11(3). pii: E376. doi: 10.3390/cancers11030376. Review.


Cyclin D1 Stability Is Partly Controlled by O-GlcNAcylation.

Masclef L, Dehennaut V, Mortuaire M, Schulz C, Leturcq M, Lefebvre T, Vercoutter-Edouart AS.

Front Endocrinol (Lausanne). 2019 Feb 22;10:106. doi: 10.3389/fendo.2019.00106. eCollection 2019.


Detection of alcohol abuse in older patients with cancer: The integration of alcohol screening questionnaires in the comprehensive geriatric assessment.

Lycke M, Martens E, Ketelaars L, Dezutter J, Lefebvre T, Pottel H, Van Eygen K, Cool L, Schofield P, Boterberg T, Debruyne PR.

J Geriatr Oncol. 2019 Sep;10(5):819-823. doi: 10.1016/j.jgo.2019.02.009. Epub 2019 Feb 26.


Subjective, but not objective, cognitive complaints impact long-term quality of life in cancer patients.

Lycke M, Lefebvre T, Pottel L, Pottel H, Ketelaars L, Stellamans K, Van Eygen K, Vergauwe P, Werbrouck P, Cool L, Boterberg T, Liefhooghe N, Schofield P, Debruyne PR.

J Psychosoc Oncol. 2019 Jul-Aug;37(4):427-440. doi: 10.1080/07347332.2018.1504154. Epub 2019 Feb 23.


Regulation and tissue-specific expression of δ-aminolevulinic acid synthases in non-syndromic sideroblastic anemias and porphyrias.

Peoc'h K, Nicolas G, Schmitt C, Mirmiran A, Daher R, Lefebvre T, Gouya L, Karim Z, Puy H.

Mol Genet Metab. 2019 Nov;128(3):190-197. doi: 10.1016/j.ymgme.2019.01.015. Epub 2019 Jan 23. Review.


Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria.

Mirmiran A, Schmitt C, Lefebvre T, Manceau H, Daher R, Oustric V, Poli A, Lacapère JJ, Moulouel B, Puy H, Karim Z, Peoc'h K, Lenglet H, Simonin S, Deybach JC, Nicolas G, Gouya L.

Am J Hum Genet. 2019 Feb 7;104(2):341-347. doi: 10.1016/j.ajhg.2018.12.021. Epub 2019 Jan 31.


The added value of an assessment of the patient's hand grip strength to the comprehensive geriatric assessment in G8-abnormal older patients with cancer in routine practice.

Lycke M, Ketelaars L, Martens E, Lefebvre T, Pottel H, Van Eygen K, Cool L, Pottel L, Kenis C, Schofield P, Boterberg T, Debruyne PR.

J Geriatr Oncol. 2019 Nov;10(6):931-936. doi: 10.1016/j.jgo.2019.01.001. Epub 2019 Jan 11.


Provisional standardization of hepcidin assays: creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference material.

Diepeveen LE, Laarakkers CMM, Martos G, Pawlak ME, Uğuz FF, Verberne KESA, van Swelm RPL, Klaver S, de Haan AFJ, Pitts KR, Bansal SS, Abbas IM, Fillet M, Lefebvre T, Geurts-Moespot AJ, Girelli D, Castagna A, Herkert M, Itkonen O, Olbina G, Tomosugi N, Westerman ME, Delatour V, Weykamp CW, Swinkels DW.

Clin Chem Lab Med. 2019 May 27;57(6):864-872. doi: 10.1515/cclm-2018-0783.


Iron deficiency diagnosed using hepcidin on critical care discharge is an independent risk factor for death and poor quality of life at one year: an observational prospective study on 1161 patients.

Lasocki S, Lefebvre T, Mayeur C, Puy H, Mebazaa A, Gayat E; FROG-ICU study group.

Crit Care. 2018 Nov 21;22(1):314. doi: 10.1186/s13054-018-2253-0.


The Many Ways by Which O-GlcNAcylation May Orchestrate the Diversity of Complex Glycosylations.

Biwi J, Biot C, Guerardel Y, Vercoutter-Edouart AS, Lefebvre T.

Molecules. 2018 Nov 2;23(11). pii: E2858. doi: 10.3390/molecules23112858. Review.


Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex.

Berthier A, Vinod M, Porez G, Steenackers A, Alexandre J, Yamakawa N, Gheeraert C, Ploton M, Maréchal X, Dubois-Chevalier J, Hovasse A, Schaeffer-Reiss C, Cianférani S, Rolando C, Bray F, Duez H, Eeckhoute J, Lefebvre T, Staels B, Lefebvre P.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11033-E11042. doi: 10.1073/pnas.1805397115. Epub 2018 Nov 5.


Cross-Dysregulation of O-GlcNAcylation and PI3K/AKT/mTOR Axis in Human Chronic Diseases.

Very N, Vercoutter-Edouart AS, Lefebvre T, Hardivillé S, El Yazidi-Belkoura I.

Front Endocrinol (Lausanne). 2018 Oct 9;9:602. doi: 10.3389/fendo.2018.00602. eCollection 2018. Review.


Dyserythropoiesis evaluated by the RED score and hepcidin:ferritin ratio predicts response to erythropoietin in lower-risk myelodysplastic syndromes.

Park S, Kosmider O, Maloisel F, Drenou B, Chapuis N, Lefebvre T, Karim Z, Puy H, Alary AS, Ducamp S, Verdier F, Bouilloux C, Rousseau A, Jacob MC, Debliquis A, Charpentier A, Gyan E, Anglaret B, Leyronnas C, Corm S, Slama B, Cheze S, Laribi K, Amé S, Rose C, Lachenal F, Toma A, Pica GM, Carre M, Garban F, Mariette C, Cahn JY, Meunier M, Herault O, Fenaux P, Wagner-Ballon O, Bardet V, Dreyfus F, Fontenay M.

Haematologica. 2019 Mar;104(3):497-504. doi: 10.3324/haematol.2018.203158. Epub 2018 Oct 4.


Hepcidin: immunoanalytic characteristics.

Wolff F, de Verneuil H, Rucheton B, Lefebvre T, Vialaret J, Ropert-Bouchet M, Cunat S, Aguilar-Martinez P, Lehmann S, Delaby C.

Ann Biol Clin (Paris). 2018 Dec 1;76(6):705-715. doi: 10.1684/abc.2018.1382. Review.


Apart From Rhoptries, Identification of Toxoplasma gondii's O-GlcNAcylated Proteins Reinforces the Universality of the O-GlcNAcome.

Aquino-Gil MO, Kupferschmid M, Shams-Eldin H, Schmidt J, Yamakawa N, Mortuaire M, Krzewinski F, Hardivillé S, Zenteno E, Rolando C, Bray F, Pérez Campos E, Dubremetz JF, Perez-Cervera Y, Schwarz RT, Lefebvre T.

Front Endocrinol (Lausanne). 2018 Aug 20;9:450. doi: 10.3389/fendo.2018.00450. eCollection 2018.


Functional erythropoietin-hepcidin axis in recombinant human erythropoietin independent haemodialysis patients.

Touzot M, Lefebvre T, Roux A, Maheas C, Ridel C, Puy H, Karim Z.

Nephrology (Carlton). 2019 Jul;24(7):751-757. doi: 10.1111/nep.13485. Epub 2019 Apr 25.


A pilot study comparing corifollitropin alfa associated with hp-HMG versus high dose rFSH antagonist protocols for ovarian stimulation in poor responders.

Mendret-Pellerin S, Leperlier F, Reignier A, Lefebvre T, Barrière P, Fréour T.

Hum Fertil (Camb). 2018 Aug 21:1-8. doi: 10.1080/14647273.2018.1504326. [Epub ahead of print]


O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions.

Leturcq M, Mortuaire M, Hardivillé S, Schulz C, Lefebvre T, Vercoutter-Edouart AS.

Cell Mol Life Sci. 2018 Dec;75(23):4321-4339. doi: 10.1007/s00018-018-2874-0. Epub 2018 Aug 1.


The SLC40A1 R178Q mutation is a recurrent cause of hemochromatosis and is associated with a novel pathogenic mechanism.

Ka C, Guellec J, Pepermans X, Kannengiesser C, Ged C, Wuyts W, Cassiman D, de Ledinghen V, Varet B, de Kerguenec C, Oudin C, Gourlaouen I, Lefebvre T, Férec C, Callebaut I, Le Gac G.

Haematologica. 2018 Nov;103(11):1796-1805. doi: 10.3324/haematol.2018.189845. Epub 2018 Jul 12.


Study of mitochondrial function in placental insufficiency.

Lefebvre T, Roche O, Seegers V, Cherif M, Khiati S, Gueguen N, Desquiret-Dumas V, Geffroy G, Blanchet O, Reynier P, Legendre G, Lenaers G, Procaccio V, Gascoin G.

Placenta. 2018 Jul;67:1-7. doi: 10.1016/j.placenta.2018.05.007. Epub 2018 May 17.


Characterization and origin of heme precursors in amniotic fluid: lessons from normal and pathological pregnancies.

Manceau H, Puy V, Schmitt CM, Gil S, Lefebvre T, Allaf B, Rosenblatt J, Gouya L, Puy H, Muller F, Peoc'h K.

Pediatr Res. 2018 Jul;84(1):80-84. doi: 10.1038/s41390-018-0011-2. Epub 2018 May 23.


Ovarian reserve and response to stimulation in women undergoing fertility preservation according to malignancy type.

Lefebvre T, Mirallié S, Leperlier F, Reignier A, Barrière P, Fréour T.

Reprod Biomed Online. 2018 Aug;37(2):201-207. doi: 10.1016/j.rbmo.2018.04.047. Epub 2018 May 2.


High urinary ferritin reflects myoglobin iron evacuation in DMD patients.

Rouillon J, Lefebvre T, Denard J, Puy V, Daher R, Ausseil J, Zocevic A, Fogel P, Peoc'h K, Wong B, Servais L, Voit T, Puy H, Karim Z, Svinartchouk F.

Neuromuscul Disord. 2018 Jul;28(7):564-571. doi: 10.1016/j.nmd.2018.03.008. Epub 2018 Mar 20.

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