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Impact of the mutational load on the virological response to a first-line rilpivirine-based regimen.

Dimeglio C, Raymond S, Nicot F, Jeanne N, Carcenac R, Lefebvre C, Izopet J; French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group .

J Antimicrob Chemother. 2018 Dec 6. doi: 10.1093/jac/dky495. [Epub ahead of print]


Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.

Walsh SR, Bastin D, Chen L, Nguyen A, Storbeck CJ, Lefebvre C, Stojdl D, Bramson JL, Bell JC, Wan Y.

J Clin Invest. 2018 Nov 13. pii: 121004. doi: 10.1172/JCI121004. [Epub ahead of print]


Sentinel lymph node biopsy without axillary lymphadenectomy after neoadjuvant chemotherapy is accurate and safe for selected patients: the GANEA 2 study.

Classe JM, Loaec C, Gimbergues P, Alran S, de Lara CT, Dupre PF, Rouzier R, Faure C, Paillocher N, Chauvet MP, Houvenaeghel G, Gutowski M, De Blay P, Verhaeghe JL, Barranger E, Lefebvre C, Ngo C, Ferron G, Palpacuer C, Campion L.

Breast Cancer Res Treat. 2018 Oct 20. doi: 10.1007/s10549-018-5004-7. [Epub ahead of print]


When to include clinical study reports and regulatory documents in systematic reviews.

Jefferson T, Doshi P, Boutron I, Golder S, Heneghan C, Hodkinson A, Jones M, Lefebvre C, Stewart LA.

BMJ Evid Based Med. 2018 Dec;23(6):210-217. doi: 10.1136/bmjebm-2018-110963. Epub 2018 Oct 11.


Testing between the gunpowder fuse and the filling-hose analogy for mental curve tracing using electroencephalography: boom!

Lefebvre C, Audevard T, Losier T, Jolicoeur P.

Neuroreport. 2018 Dec 5;29(17):1437-1442. doi: 10.1097/WNR.0000000000001114.


Improving control in microbial cell factories: from single-cell to large-scale bioproduction.

Delvigne F, Zacchetti B, Fickers P, Fifani B, Roulling F, Lefebvre C, Neubauer P, Junne S.

FEMS Microbiol Lett. 2018 Nov 1;365(22). doi: 10.1093/femsle/fny236.


Hyperprogressive Disease in Patients With Advanced Non-Small Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or With Single-Agent Chemotherapy.

Ferrara R, Mezquita L, Texier M, Lahmar J, Audigier-Valette C, Tessonnier L, Mazieres J, Zalcman G, Brosseau S, Le Moulec S, Leroy L, Duchemann B, Lefebvre C, Veillon R, Westeel V, Koscielny S, Champiat S, Ferté C, Planchard D, Remon J, Boucher ME, Gazzah A, Adam J, Bria E, Tortora G, Soria JC, Besse B, Caramella C.

JAMA Oncol. 2018 Nov 1;4(11):1543-1552. doi: 10.1001/jamaoncol.2018.3676.


Linking process and effects of intersectoral action on local neighbourhoods: systemic modelling based on Actor-Network Theory.

Bilodeau A, Galarneau M, Lefebvre C, Potvin L.

Sociol Health Illn. 2018 Sep 4. doi: 10.1111/1467-9566.12813. [Epub ahead of print]


Autophagy mediates phosphatidylserine exposure and phagosome degradation during apoptosis through specific functions of GABARAP/LGG-1 and LC3/LGG-2.

Jenzer C, Simionato E, Largeau C, Scarcelli V, Lefebvre C, Legouis R.

Autophagy. 2018 Sep 10:1-14. doi: 10.1080/15548627.2018.1512452. [Epub ahead of print]


Added Value of Whole-Exome and Transcriptome Sequencing for Clinical Molecular Screenings of Advanced Cancer Patients With Solid Tumors.

Koeppel F, Bobard A, Lefebvre C, Pedrero M, Deloger M, Boursin Y, Richon C, Chen-Min-Tao R, Robert G, Meurice G, Rouleau E, Michiels S, Massard C, Scoazec JY, Solary E, Soria JC, André F, Lacroix L.

Cancer J. 2018 Jul/Aug;24(4):153-162. doi: 10.1097/PPO.0000000000000322.


The use of clinical study reports to enhance the quality of systematic reviews: a survey of systematic review authors.

Hodkinson A, Dietz KC, Lefebvre C, Golder S, Jones M, Doshi P, Heneghan C, Jefferson T, Boutron I, Stewart L.

Syst Rev. 2018 Aug 8;7(1):117. doi: 10.1186/s13643-018-0766-x.


An evolution during a century of leadership, scholarship, mentorship, and fellowship.

Taylor JC, Lefebvre CA, Weber HP, Masri R, Wu BM.

J Prosthet Dent. 2018 Jun;119(6):865-866. doi: 10.1016/j.prosdent.2018.04.004. No abstract available.


Legal Considerations in the Remediation and Dismissal of Graduate Medical Trainees.

Lefebvre C, Williamson K, Moffett P, Cummings A, Gianopulos B, Winters E, Sokolosky M.

J Grad Med Educ. 2018 Jun;10(3):253-257. doi: 10.4300/JGME-D-17-00813.1. No abstract available.


Diversity of hepatitis E virus genotype 3.

Nicot F, Jeanne N, Roulet A, Lefebvre C, Carcenac R, Manno M, Dubois M, Kamar N, Lhomme S, Abravanel F, Izopet J.

Rev Med Virol. 2018 Sep;28(5):e1987. doi: 10.1002/rmv.1987. Epub 2018 Jun 25.


The HEART Pathway Randomized Controlled Trial One-year Outcomes.

Stopyra JP, Riley RF, Hiestand BC, Russell GB, Hoekstra JW, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Elliott SB, Herrington DM, Burke GL, Miller CD, Mahler SA.

Acad Emerg Med. 2018 Jun 19. doi: 10.1111/acem.13504. [Epub ahead of print]


Factors associated with pregnancy after in vitro fertilization in infertile patients with posterior deep pelvic endometriosis: A retrospective study.

Rubod C, Fouquet A, Bartolo S, Lepage J, Capelle A, Lefebvre C, Kamus E, Dewailly D, Collinet P.

J Gynecol Obstet Hum Reprod. 2018 Jun 14. pii: S2468-7847(18)30153-3. doi: 10.1016/j.jogoh.2018.06.002. [Epub ahead of print]


Transforming the prostatic tumor microenvironment with oncolytic virotherapy.

Atherton MJ, Stephenson KB, Tzelepis F, Bakhshinyan D, Nikota JK, Son HH, Jirovec A, Lefebvre C, Dvorkin-Gheva A, Ashkar AA, Wan Y, Stojdl DF, Belanger EC, Breau RH, Bell JC, Saad F, Singh SK, Diallo JS, Lichty BD.

Oncoimmunology. 2018 Mar 27;7(7):e1445459. doi: 10.1080/2162402X.2018.1445459. eCollection 2018.


Performance comparison of deep sequencing platforms for detecting HIV-1 variants in the pol gene.

Nicot F, Jeanne N, Raymond S, Delfour O, Carcenac R, Lefebvre C, Sauné K, Delobel P, Izopet J.

J Med Virol. 2018 Sep;90(9):1486-1492. doi: 10.1002/jmv.25224. Epub 2018 May 25.


Genome-wide RNAi Screening to Identify Host Factors That Modulate Oncolytic Virus Therapy.

Allan KJ, Mahoney DJ, Baird SD, Lefebvre CA, Stojdl DF.

J Vis Exp. 2018 Apr 3;(134). doi: 10.3791/56913.


The Journal of Prosthetic Dentistry: A historical perspective.

Marchack BW, Sharma A, Lefebvre CA.

J Prosthet Dent. 2018 Apr;119(4):497-498. doi: 10.1016/j.prosdent.2018.02.009. No abstract available.


HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness.

Lefebvre C, Boulon R, Ducoux M, Gavalda S, Laval F, Jamet S, Eynard N, Lemassu A, Cam K, Bousquet MP, Bardou F, Burlet-Schiltz O, Daffé M, Quémard A.

Sci Rep. 2018 Apr 16;8(1):6034. doi: 10.1038/s41598-018-24380-5.


Surgery using plasma energy for deep endometriosis: A quality of life assessment.

Delbos L, Bouet PE, Catala L, Lefebvre C, Teyssedou C, Descamps P, Legendre G.

J Gynecol Obstet Hum Reprod. 2018 Oct;47(8):359-364. doi: 10.1016/j.jogoh.2018.04.005. Epub 2018 Apr 11.


Cerebral venous thrombosis revealing Behçet's disease in a Moroccan patient: A case report and literature review.

Krumb E, Lefebvre C, Peeters A, Hermans C.

SAGE Open Med Case Rep. 2018 Mar 28;6:2050313X18767053. doi: 10.1177/2050313X18767053. eCollection 2018.


Molecular dissection of engraftment in a xenograft model of myelodysplastic syndromes.

Meunier M, Dussiau C, Mauz N, Alary AS, Lefebvre C, Szymanski G, Pezet M, Blanquet F, Kosmider O, Park S.

Oncotarget. 2018 Feb 20;9(19):14993-15000. doi: 10.18632/oncotarget.24538. eCollection 2018 Mar 13.


About a case of traumatic separation of the cervix from the uterine corpus, diagnosed in a context of infertility.

Vignolle J, Lefebvre C, Lucot JP, Rubod C.

J Gynecol Obstet Hum Reprod. 2018 Jun;47(6):257-260. doi: 10.1016/j.jogoh.2018.03.007. Epub 2018 Mar 21.


HIV-1 genotypic resistance testing using the Vela automated next-generation sequencing platform.

Raymond S, Nicot F, Carcenac R, Lefebvre C, Jeanne N, Saune K, Delobel P, Izopet J.

J Antimicrob Chemother. 2018 May 1;73(5):1152-1157. doi: 10.1093/jac/dky003.


Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.

Forcellini E, Boutin S, Lefebvre CA, Shayhidin EE, Boulanger MC, Rhéaume G, Barbeau X, Lagüe P, Mathieu P, Paquin JF.

Eur J Med Chem. 2018 Mar 10;147:130-149. doi: 10.1016/j.ejmech.2018.01.094. Epub 2018 Feb 2.


Challenges of identifying unpublished data from clinical trials: Getting the best out of clinical trials registers and other novel sources.

Isojarvi J, Wood H, Lefebvre C, Glanville J.

Res Synth Methods. 2018 Dec;9(4):561-578. doi: 10.1002/jrsm.1294. Epub 2018 Feb 21.


Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas.

Zajac O, Raingeaud J, Libanje F, Lefebvre C, Sabino D, Martins I, Roy P, Benatar C, Canet-Jourdan C, Azorin P, Polrot M, Gonin P, Benbarche S, Souquere S, Pierron G, Nowak D, Bigot L, Ducreux M, Malka D, Lobry C, Scoazec JY, Eveno C, Pocard M, Perfettini JL, Elias D, Dartigues P, Goéré D, Jaulin F.

Nat Cell Biol. 2018 Mar;20(3):296-306. doi: 10.1038/s41556-017-0027-6. Epub 2018 Feb 5.


Photochemically Induced Intramolecular Radical Cyclization Reactions with Imines.

Lefebvre C, Michelin C, Martzel T, Djou'ou Mvondo V, Bulach V, Abe M, Hoffmann N.

J Org Chem. 2018 Feb 16;83(4):1867-1875. doi: 10.1021/acs.joc.7b02810. Epub 2018 Jan 26.


Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes.

Meunier M, Ancelet S, Lefebvre C, Arnaud J, Garrel C, Pezet M, Wang Y, Faure P, Szymanski G, Duployez N, Preudhomme C, Biard D, Polack B, Cahn JY, Moulis JM, Park S.

Oncotarget. 2017 Nov 6;8(62):105510-105524. doi: 10.18632/oncotarget.22299. eCollection 2017 Dec 1.


The Independent Gradient Model: A New Approach for Probing Strong and Weak Interactions in Molecules from Wave Function Calculations.

Lefebvre C, Khartabil H, Boisson JC, Contreras-García J, Piquemal JP, Hénon E.

Chemphyschem. 2018 Mar 19;19(6):724-735. doi: 10.1002/cphc.201701325. Epub 2018 Jan 30.


"Double-hit" chronic lymphocytic leukemia: An aggressive subgroup with 17p deletion and 8q24 gain.

Chapiro E, Lesty C, Gabillaud C, Durot E, Bouzy S, Armand M, Le Garff-Tavernier M, Bougacha N, Struski S, Bidet A, Laharanne E, Barin C, Veronese L, Prié N, Eclache V, Gaillard B, Michaux L, Lefebvre C, Gaillard JB, Terré C, Penther D, Bastard C, Nadal N, Fert-Ferrer S, Auger N, Godon C, Sutton L, Tournilhac O, Susin SA, Nguyen-Khac F; GroupeFrancophone de Cytogénétique Hématologique(GFCH) and the French Innovative Leukemia Organization (FILO) group.

Am J Hematol. 2018 Mar;93(3):375-382. doi: 10.1002/ajh.24990. Epub 2017 Dec 18.


Assessing the performance of methodological search filters to improve the efficiency of evidence information retrieval: five literature reviews and a qualitative study.

Lefebvre C, Glanville J, Beale S, Boachie C, Duffy S, Fraser C, Harbour J, McCool R, Smith L.

Health Technol Assess. 2017 Nov;21(69):1-148. doi: 10.3310/hta21690.


Age and factors associated with access and time to post-operative adjuvant chemotherapy in colon cancer: a French epidemiological study.

Capsec J, Lefebvre C, Chupé F, Heitzmann P, Raveneau C, Dardaine-Giraud V, Sauger C, Lagasse JP, Kraft K, Linassier C, Dorval E.

J Gastrointest Oncol. 2017 Oct;8(5):842-849. doi: 10.21037/jgo.2017.06.13.


Activating Peripheral Innate Immunity Enables Safe and Effective Oncolytic Virotherapy in the Brain.

Balathasan L, Tang VA, Yadollahi B, Brun J, Labelle M, Lefebvre C, Swift SL, Stojdl DF.

Mol Ther Oncolytics. 2017 Sep 15;7:45-56. doi: 10.1016/j.omto.2017.09.004. eCollection 2017 Dec 15.


Questions Regarding Study Design and Analysis in "Previous Suicide Attempt and its Association With Method Used in a Suicide Death".

Lefebvre C, Malhamé I, Sewitch MJ.

Am J Prev Med. 2017 Nov;53(5):e191. doi: 10.1016/j.amepre.2017.05.012. No abstract available.


Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane.

Chiaradia L, Lefebvre C, Parra J, Marcoux J, Burlet-Schiltz O, Etienne G, Tropis M, Daffé M.

Sci Rep. 2017 Oct 9;7(1):12807. doi: 10.1038/s41598-017-12718-4.


Mathematical bias in assessment of placental residual blood volume.

Rigo V, Lefebvre C, Kalenga M.

J Perinatol. 2017 Oct;37(10):1166. doi: 10.1038/jp.2017.85. No abstract available.


Bioconcentration of polycyclic musks in fathead minnows caged in a wastewater effluent plume.

Lefebvre C, Kimpe LE, Metcalfe CD, Trudeau VL, Blais JM.

Environ Pollut. 2017 Dec;231(Pt 2):1593-1600. doi: 10.1016/j.envpol.2017.09.062. Epub 2017 Sep 28.


Suppression of Multiphoton Resonances in Driven Quantum Systems via Pulse Shape Optimization.

Gagnon D, Fillion-Gourdeau F, Dumont J, Lefebvre C, MacLean S.

Phys Rev Lett. 2017 Aug 4;119(5):053203. doi: 10.1103/PhysRevLett.119.053203. Epub 2017 Aug 3.


Customized Viral Immunotherapy for HPV-Associated Cancer.

Atherton MJ, Stephenson KB, Pol J, Wang F, Lefebvre C, Stojdl DF, Nikota JK, Dvorkin-Gheva A, Nguyen A, Chen L, Johnson-Obaseki S, Villeneuve PJ, Diallo JS, Dimitroulakos J, Wan Y, Lichty BD.

Cancer Immunol Res. 2017 Oct;5(10):847-859. doi: 10.1158/2326-6066.CIR-17-0102. Epub 2017 Sep 14.


Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke.

Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L, Arquizan C, Béjot Y, Vuillier F, Detante O, Guidoux C, Canaple S, Vaduva C, Dequatre-Ponchelle N, Sibon I, Garnier P, Ferrier A, Timsit S, Robinet-Borgomano E, Sablot D, Lacour JC, Zuber M, Favrole P, Pinel JF, Apoil M, Reiner P, Lefebvre C, Guérin P, Piot C, Rossi R, Dubois-Randé JL, Eicher JC, Meneveau N, Lusson JR, Bertrand B, Schleich JM, Godart F, Thambo JB, Leborgne L, Michel P, Pierard L, Turc G, Barthelet M, Charles-Nelson A, Weimar C, Moulin T, Juliard JM, Chatellier G; CLOSE Investigators.

N Engl J Med. 2017 Sep 14;377(11):1011-1021. doi: 10.1056/NEJMoa1705915.


[Lung dose constraints for normo-fractionated radiotherapy and for stereotactic body radiation therapy].

Blais E, Pichon B, Mampuya A, Antoine M, Lagarde P, Kantor G, Breton-Callu C, Lefebvre C, Gerard M, Aamarcha A, Ozsahin M, Bourhis J, Maingon P, Troussier I, Pourel N.

Cancer Radiother. 2017 Oct;21(6-7):584-596. doi: 10.1016/j.canrad.2017.07.046. Epub 2017 Sep 5. Review. French.


Feasibility and safety of intact cord resuscitation in newborn infants with congenital diaphragmatic hernia (CDH).

Lefebvre C, Rakza T, Weslinck N, Vaast P, Houfflin-Debarge V, Mur S, Storme L; French CDH Study Group.

Resuscitation. 2017 Nov;120:20-25. doi: 10.1016/j.resuscitation.2017.08.233. Epub 2017 Aug 30.


ESCRT and autophagies: Endosomal functions and beyond.

Lefebvre C, Legouis R, Culetto E.

Semin Cell Dev Biol. 2018 Feb;74:21-28. doi: 10.1016/j.semcdb.2017.08.014. Epub 2017 Aug 12. Review.


Impact of cytogenetic abnormalities in adults with Ph-negative B-cell precursor acute lymphoblastic leukemia.

Lafage-Pochitaloff M, Baranger L, Hunault M, Cuccuini W, Lefebvre C, Bidet A, Tigaud I, Eclache V, Delabesse E, Bilhou-Nabéra C, Terré C, Chapiro E, Gachard N, Mozziconacci MJ, Ameye G, Porter S, Grardel N, Béné MC, Chalandon Y, Graux C, Huguet F, Lhéritier V, Ifrah N, Dombret H; Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL).

Blood. 2017 Oct 19;130(16):1832-1844. doi: 10.1182/blood-2017-05-783852. Epub 2017 Aug 8.


Efficient and secure outsourcing of genomic data storage.

Sousa JS, Lefebvre C, Huang Z, Raisaro JL, Aguilar-Melchor C, Killijian MO, Hubaux JP.

BMC Med Genomics. 2017 Jul 26;10(Suppl 2):46. doi: 10.1186/s12920-017-0275-0.


Accurately extracting the signature of intermolecular interactions present in the NCI plot of the reduced density gradient versus electron density.

Lefebvre C, Rubez G, Khartabil H, Boisson JC, Contreras-García J, Hénon E.

Phys Chem Chem Phys. 2017 Jul 21;19(27):17928-17936. doi: 10.1039/c7cp02110k. Epub 2017 Jun 30.


Validation of the No Objective Testing Rule and Comparison to the HEART Pathway.

Stopyra JP, Miller CD, Hiestand BC, Lefebvre CW, Nicks BA, Cline DM, Askew KL, Riley RF, Russell GB, Hoekstra JW, Mahler SA.

Acad Emerg Med. 2017 Sep;24(9):1165-1168. doi: 10.1111/acem.13221. Epub 2017 Aug 8.

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