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(Deep) Learning Your Left From Your Right.

Leeson P.

JACC Cardiovasc Imaging. 2019 May 9. pii: S1936-878X(19)30317-1. doi: 10.1016/j.jcmg.2019.03.015. [Epub ahead of print] No abstract available.


Artificial Intelligence in Cardiovascular Imaging: JACC State-of-the-Art Review.

Dey D, Slomka PJ, Leeson P, Comaniciu D, Shrestha S, Sengupta PP, Marwick TH.

J Am Coll Cardiol. 2019 Mar 26;73(11):1317-1335. doi: 10.1016/j.jacc.2018.12.054. Review.


Neurohumoral and ambulatory haemodynamic adaptations following isometric exercise training in unmedicated hypertensive patients.

Taylor KA, Wiles JD, Coleman DA, Leeson P, Sharma R, O'Driscoll JM.

J Hypertens. 2019 Apr;37(4):827-836. doi: 10.1097/HJH.0000000000001922.


Automated Myocardial Wall Motion Classification using Handcrafted Features vs a Deep CNN-based mapping.

Omar HA, Patra A, Domingos JS, Leeson P, Noblel AJ.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3140-3143. doi: 10.1109/EMBC.2018.8513063.


Improving Visual Detection of Wall Motion Abnormality with Echocardiographic Image Enhancing Methods.

Omar HA, Domingos JS, Patra A, Leeson P, Noble JA.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1128-1131. doi: 10.1109/EMBC.2018.8512537.


Trial of exercise to prevent HypeRtension in young adults (TEPHRA) a randomized controlled trial: study protocol.

Williamson W, Huckstep OJ, Frangou E, Mohamed A, Tan C, Alsharqi M, Bertagnolli M, Lapidaire W, Newton J, Hanssen H, McManus R, Dawes H, Foster C, Lewandowski AJ, Leeson P.

BMC Cardiovasc Disord. 2018 Nov 6;18(1):208. doi: 10.1186/s12872-018-0944-8.


Artificial intelligence and echocardiography.

Alsharqi M, Woodward WJ, Mumith JA, Markham DC, Upton R, Leeson P.

Echo Res Pract. 2018 Dec 1;5(4):R115-R125. doi: 10.1530/ERP-18-0056. Review.


Neonatal Micro-RNA Profile Determines Endothelial Function in Offspring of Hypertensive Pregnancies.

Yu GZ, Reilly S, Lewandowski AJ, Aye CYL, Simpson LJ, Newton L, Davis EF, Zhu SJ, Fox WR, Goel A, Watkins H, Channon KM, Watt SM, Kyriakou T, Leeson P.

Hypertension. 2018 Oct;72(4):937-945. doi: 10.1161/HYPERTENSIONAHA.118.11343. Epub 2018 Aug 20.


The Role of Neuropeptide Y in Cardiovascular Health and Disease.

Tan CMJ, Green P, Tapoulal N, Lewandowski AJ, Leeson P, Herring N.

Front Physiol. 2018 Sep 19;9:1281. doi: 10.3389/fphys.2018.01281. eCollection 2018. Review.


Neurohumoral and ambulatory haemodynamic adaptations following isometric exercise training in unmedicated hypertensive patients.

Taylor KA, Wiles JD, Coleman DA, Leeson P, Sharma R, O'Driscoll JM.

J Hypertens. 2018 Sep 17. doi: 10.1097/HJH.0000000000001922. [Epub ahead of print]


Can diet influence cardiac geometry and function in young adults?

Mohamed A, Lewandowski AJ, Huckstep O, Leeson P.

Eur J Prev Cardiol. 2018 Oct;25(15):1585-1586. doi: 10.1177/2047487318796292. Epub 2018 Aug 28. No abstract available.


Association of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults.

Williamson W, Lewandowski AJ, Forkert ND, Griffanti L, Okell TW, Betts J, Boardman H, Siepmann T, McKean D, Huckstep O, Francis JM, Neubauer S, Phellan R, Jenkinson M, Doherty A, Dawes H, Frangou E, Malamateniou C, Foster C, Leeson P.

JAMA. 2018 Aug 21;320(7):665-673. doi: 10.1001/jama.2018.11498.


Artificial intelligence: a new clinical support tool for stress echocardiography.

Alsharqi M, Upton R, Mumith A, Leeson P.

Expert Rev Med Devices. 2018 Aug;15(8):513-515. doi: 10.1080/17434440.2018.1497482. Epub 2018 Jul 19. Review. No abstract available.


Self-Management of Postnatal Hypertension: The SNAP-HT Trial.

Cairns AE, Tucker KL, Leeson P, Mackillop LH, Santos M, Velardo C, Salvi D, Mort S, Mollison J, Tarassenko L, McManus RJ; SNAP-HT Investigators.

Hypertension. 2018 Aug;72(2):425-432. doi: 10.1161/HYPERTENSIONAHA.118.10911. Epub 2018 Jul 2.


Cardiometabolic and reproductive health in young women: Making the right choices.

Elmahi E, Leeson P.

Eur J Prev Cardiol. 2018 Jul;25(10):1040-1041. doi: 10.1177/2047487318780061. Epub 2018 May 30. No abstract available.


Neonatal autonomic function after pregnancy complications and early cardiovascular development.

Aye CYL, Lewandowski AJ, Oster J, Upton R, Davis E, Kenworthy Y, Boardman H, Yu GZ, Siepmann T, Adwani S, McCormick K, Sverrisdottir YB, Leeson P.

Pediatr Res. 2018 Jul;84(1):85-91. doi: 10.1038/s41390-018-0021-0. Epub 2018 May 23.


Do Young Women Need Treatment for Hypertension After Pregnancy Complications?

Aye CYL, Elmahi E, Boardman H, Leeson P.

J Am Heart Assoc. 2018 May 13;7(10). pii: e009159. doi: 10.1161/JAHA.118.009159. No abstract available.


Impact of Physicochemical Properties on Dose and Hepatotoxicity of Oral Drugs.

Leeson PD.

Chem Res Toxicol. 2018 Jun 18;31(6):494-505. doi: 10.1021/acs.chemrestox.8b00044. Epub 2018 May 11.


Like sheep, like humans? Right ventricular remodelling in a preterm-born ovine model.

Mohamed A, Leeson P, Lewandowski AJ.

J Physiol. 2018 Dec;596(23):5505-5506. doi: 10.1113/JP276067. Epub 2018 May 10. No abstract available.


Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations.

Young RJ, Leeson PD.

J Med Chem. 2018 Aug 9;61(15):6421-6467. doi: 10.1021/acs.jmedchem.8b00180. Epub 2018 Apr 25. Review.


Physiological Stress Elicits Impaired Left Ventricular Function in Preterm-Born Adults.

Huckstep OJ, Williamson W, Telles F, Burchert H, Bertagnolli M, Herdman C, Arnold L, Smillie R, Mohamed A, Boardman H, McCormick K, Neubauer S, Leeson P, Lewandowski AJ.

J Am Coll Cardiol. 2018 Mar 27;71(12):1347-1356. doi: 10.1016/j.jacc.2018.01.046.


Postpartum management of hypertensive disorders of pregnancy: a systematic review.

Cairns AE, Pealing L, Duffy JMN, Roberts N, Tucker KL, Leeson P, MacKillop LH, McManus RJ.

BMJ Open. 2017 Nov 28;7(11):e018696. doi: 10.1136/bmjopen-2017-018696. Review.


Effects of Vitamin D on Blood Pressure, Arterial Stiffness, and Cardiac Function in Older People After 1 Year: BEST-D (Biochemical Efficacy and Safety Trial of Vitamin D).

Tomson J, Hin H, Emberson J, Kurien R, Lay M, Cox J, Hill M, Arnold L, Leeson P, Armitage J, Clarke R.

J Am Heart Assoc. 2017 Oct 24;6(10). pii: e005707. doi: 10.1161/JAHA.117.005707.


Protocol and quality assurance for carotid imaging in 100,000 participants of UK Biobank: development and assessment.

Coffey S, Lewandowski AJ, Garratt S, Meijer R, Lynum S, Bedi R, Paterson J, Yaqub M, Noble JA, Neubauer S, Petersen SE, Allen N, Sudlow C, Collins R, Matthews PM, Leeson P.

Eur J Prev Cardiol. 2017 Nov;24(17):1799-1806. doi: 10.1177/2047487317732273. Epub 2017 Sep 19.


Author response: Long-term cerebral white and gray matter changes after preeclampsia.

Siepmann T, Boardman H, Bilderbeck A, Griffanti L, Kenworthy Y, Zwager C, McKean D, Francis J, Neubauer S, Yu GZ, Lewandowski AJ, Sverrisdottir YB, Leeson P.

Neurology. 2017 Sep 19;89(12):1309-1310. doi: 10.1212/WNL.0000000000004404. No abstract available.


Two-Dimensional Echocardiography Estimates of Fetal Ventricular Mass throughout Gestation.

Aye CYL, Lewandowski AJ, Ohuma EO, Upton R, Packham A, Kenworthy Y, Roseman F, Norris T, Molloholli M, Wanyonyi S, Papageorghiou AT, Leeson P.

Fetal Diagn Ther. 2018;44(1):18-27. doi: 10.1159/000477964. Epub 2017 Aug 12.


Cardiac Disease after Pregnancy: A Growing Problem.

Aye CY, Boardman H, Leeson P.

Eur Cardiol. 2017 Aug;12(1):20-23. doi: 10.15420/ecr.2017:4:1. Review.


Predicting the future with echocardiography: Looking outside the heart?

Leeson P.

Eur J Prev Cardiol. 2017 Sep;24(14):1515-1516. doi: 10.1177/2047487317722435. Epub 2017 Jul 18. No abstract available.


A New Risk Factor for Early Heart Failure: Preterm Birth.

Leeson P, Lewandowski AJ.

J Am Coll Cardiol. 2017 May 30;69(21):2643-2645. doi: 10.1016/j.jacc.2017.03.574. No abstract available.


Hypertension: Hypertension in pregnancy: a risk factor for the whole family?

Yu GZ, Leeson P.

Nat Rev Nephrol. 2017 Jun;13(6):326-327. doi: 10.1038/nrneph.2017.54. Epub 2017 Apr 19. No abstract available.


Disproportionate cardiac hypertrophy during early postnatal development in infants born preterm.

Aye CYL, Lewandowski AJ, Lamata P, Upton R, Davis E, Ohuma EO, Kenworthy Y, Boardman H, Wopperer S, Packham A, Adwani S, McCormick K, Papageorghiou AT, Leeson P.

Pediatr Res. 2017 Jul;82(1):36-46. doi: 10.1038/pr.2017.96. Epub 2017 May 24.


Long-term cerebral white and gray matter changes after preeclampsia.

Siepmann T, Boardman H, Bilderbeck A, Griffanti L, Kenworthy Y, Zwager C, McKean D, Francis J, Neubauer S, Yu GZ, Lewandowski AJ, Sverrisdottir YB, Leeson P.

Neurology. 2017 Mar 28;88(13):1256-1264. doi: 10.1212/WNL.0000000000003765. Epub 2017 Feb 24.


Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort.

Petersen SE, Aung N, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Francis JM, Khanji MY, Lukaschuk E, Lee AM, Carapella V, Kim YJ, Leeson P, Piechnik SK, Neubauer S.

J Cardiovasc Magn Reson. 2017 Feb 3;19(1):18. doi: 10.1186/s12968-017-0327-9.


Survey of healthcare professionals regarding adjustment of antihypertensive medication(s) in the postnatal period in women with hypertensive disorders of pregnancy.

Cairns AE, Tucker KL, Leeson P, Mackillop L, McManus RJ.

Pregnancy Hypertens. 2016 Oct;6(4):256-258. doi: 10.1016/j.preghy.2016.08.240. Epub 2016 Aug 31.


Aortic stiffness and blood pressure variability in young people: a multimodality investigation of central and peripheral vasculature.

Boardman H, Lewandowski AJ, Lazdam M, Kenworthy Y, Whitworth P, Zwager CL, Francis JM, Aye CY, Williamson W, Neubauer S, Leeson P.

J Hypertens. 2017 Mar;35(3):513-522. doi: 10.1097/HJH.0000000000001192.


Invited Commentary: Hypertension During Pregnancy and Offspring Microvascular Structure-Insights From the Retinal Microcirculation.

Huckstep O, Lewandowski AJ, Leeson P.

Am J Epidemiol. 2016 Nov 1;184(9):616-618. Epub 2016 Oct 15.


12th WINFOCUS world congress on ultrasound in emergency and critical care.

Acar Y, Tezel O, Salman N, Cevik E, Algaba-Montes M, Oviedo-García A, Patricio-Bordomás M, Mahmoud MZ, Sulieman A, Ali A, Mustafa A, Abdelrahman I, Bahar M, Ali O, Lester Kirchner H, Prosen G, Anzic A, Leeson P, Bahreini M, Rasooli F, Hosseinnejad H, Blecher G, Meek R, Egerton-Warburton D, Ćuti EĆ, Belina S, Vančina T, Kovačević I, Rustemović N, Chang I, Lee JH, Kwak YH, Kim do K, Cheng CY, Pan HY, Kung CT, Ćurčić E, Pritišanac E, Planinc I, Medić MG, Radonić R, Fasina A, Dean AJ, Panebianco NL, Henwood PS, Fochi O, Favarato M, Bonanomi E, Tomić I, Ha Y, Toh H, Harmon E, Chan W, Baston C, Morrison G, Shofer F, Hua A, Kim S, Tsung J, Gunaydin I, Kekec Z, Ay MO, Kim J, Kim J, Choi G, Shim D, Lee JH, Ambrozic J, Prokselj K, Lucovnik M, Simenc GB, Mačiulienė A, Maleckas A, Kriščiukaitis A, Mačiulis V, Macas A, Mohite S, Narancsik Z, Možina H, Nikolić S, Hansel J, Petrovčič R, Mršić U, Orlob S, Lerchbaumer M, Schönegger N, Kaufmann R, Pan CI, Wu CH, Pasquale S, Doniger SJ, Yellin S, Chiricolo G, Potisek M, Drnovšek B, Leskovar B, Robinson K, Kraft C, Moser B, Davis S, Layman S, Sayeed Y, Minardi J, Pasic IS, Dzananovic A, Pasic A, Zubovic SV, Hauptman AG, Brajkovic AV, Babel J, Peklic M, Radonic V, Bielen L, Ming PW, Yezid NH, Mohammed FL, Huda ZA, Ismail WN, Isa WY, Fauzi H, Seeva P, Mazlan MZ.

Crit Ultrasound J. 2016 Sep;8(Suppl 1):12. doi: 10.1186/s13089-016-0046-8. Erratum in: Crit Ultrasound J. 2016 Dec;8(1):13.


Association of Maternal Antiangiogenic Profile at Birth With Early Postnatal Loss of Microvascular Density in Offspring of Hypertensive Pregnancies.

Yu GZ, Aye CY, Lewandowski AJ, Davis EF, Khoo CP, Newton L, Yang CT, Al Haj Zen A, Simpson LJ, O'Brien K, Cook DA, Granne I, Kyriakou T, Channon KM, Watt SM, Leeson P.

Hypertension. 2016 Sep;68(3):749-59. doi: 10.1161/HYPERTENSIONAHA.116.07586. Epub 2016 Jul 25.


Quality guidelines for oral drug candidates: dose, solubility and lipophilicity.

Bayliss MK, Butler J, Feldman PL, Green DV, Leeson PD, Palovich MR, Taylor AJ.

Drug Discov Today. 2016 Oct;21(10):1719-1727. doi: 10.1016/j.drudis.2016.07.007. Epub 2016 Jul 14. Review.


Breast Milk Consumption in Preterm Neonates and Cardiac Shape in Adulthood.

Lewandowski AJ, Lamata P, Francis JM, Piechnik SK, Ferreira VM, Boardman H, Neubauer S, Singhal A, Leeson P, Lucas A.

Pediatrics. 2016 Jul;138(1). pii: e20160050. doi: 10.1542/peds.2016-0050. Epub 2016 Jun 14.


Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis.

Williamson W, Foster C, Reid H, Kelly P, Lewandowski AJ, Boardman H, Roberts N, McCartney D, Huckstep O, Newton J, Dawes H, Gerry S, Leeson P.

Hypertension. 2016 Jul;68(1):78-87. doi: 10.1161/HYPERTENSIONAHA.116.07431. Epub 2016 May 23. Review.


Time to rethink physical activity advice and blood pressure: A role for occupation-based interventions?

Williamson W, Boardman H, Lewandowski AJ, Leeson P.

Eur J Prev Cardiol. 2016 Jul;23(10):1051-3. doi: 10.1177/2047487316645008. Epub 2016 Apr 26. No abstract available.


Corrigendum: Comprehensive multi-modality assessment of regional and global arterial structure and function in adults born preterm.

Boardman H, Birse K, Davis EF, Whitworth P, Aggarwal V, Lewandowski AJ, Leeson P.

Hypertens Res. 2016 Aug;39(8):620. doi: 10.1038/hr.2016.36. Epub 2016 Apr 14. No abstract available.


Preterm Birth and Hypertension: Is There a Link?

Bertagnolli M, Luu TM, Lewandowski AJ, Leeson P, Nuyt AM.

Curr Hypertens Rep. 2016 Apr;18(4):28. doi: 10.1007/s11906-016-0637-6. Review.


Molecular inflation, attrition and the rule of five.

Leeson PD.

Adv Drug Deliv Rev. 2016 Jun 1;101:22-33. doi: 10.1016/j.addr.2016.01.018. Epub 2016 Feb 1. Review.


Haemodynamic changes in pregnancy: what can we learn from combined datasets?

Boardman H, Ormerod O, Leeson P.

Heart. 2016 Apr;102(7):490-1. doi: 10.1136/heartjnl-2015-309166. Epub 2016 Jan 29. No abstract available.


Pregnancy and Long-Term Maternal Cardiovascular Health: Progress Through Harmonization of Research Cohorts and Biobanks.

Staff AC, Redman CW, Williams D, Leeson P, Moe K, Thilaganathan B, Magnus P, Steegers EA, Tsigas EZ, Ness RB, Myatt L, Poston L, Roberts JM; Global Pregnancy Collaboration (CoLab).

Hypertension. 2016 Feb;67(2):251-60. doi: 10.1161/HYPERTENSIONAHA.115.06357. Epub 2015 Dec 14. Review. No abstract available.


Preterm birth: risk factor for early-onset chronic diseases.

Luu TM, Katz SL, Leeson P, Thébaud B, Nuyt AM.

CMAJ. 2016 Jul 12;188(10):736-746. doi: 10.1503/cmaj.150450. Epub 2015 Dec 7. Review. No abstract available.


Oxfordshire Women and Their Children's Health (OxWATCH): protocol for a prospective cohort feasibility study.

Harrison S, Petkovic G, Chevassut A, Brook L, Higgins N, Kenworthy Y, Selwood M, Snelgar T, Arnold L, Boardman H, Heneghan C, Leeson P, Redman C, Granne I.

BMJ Open. 2015 Nov 9;5(11):e009282. doi: 10.1136/bmjopen-2015-009282. Erratum in: BMJ Open. 2017 Jun 26;7(6):e009282corr1.


Comprehensive multi-modality assessment of regional and global arterial structure and function in adults born preterm.

Boardman H, Birse K, Davis EF, Whitworth P, Aggarwal V, Lewandowski AJ, Leeson P.

Hypertens Res. 2016 Jan;39(1):39-45. doi: 10.1038/hr.2015.102. Epub 2015 Sep 24. Erratum in: Hypertens Res. 2016 Aug;39(8):620.

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