Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39

1.
2.

Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine.

Johansson S, Read J, Oliver S, Steinberg M, Li Y, Lisbon E, Mathews D, Leese PT, Martin P.

Clin Pharmacokinet. 2014 Sep;53(9):837-47. doi: 10.1007/s40262-014-0161-2. Erratum in: Clin Pharmacokinet. 2014 Nov;53(11):1063.

PMID:
25117183
3.

Oral alitretinoin: a review of the clinical pharmacokinetics and pharmacodynamics.

Schmitt-Hoffmann AH, Roos B, Schoetzau A, Leese PT, Meyer I, van de Wetering J, Kovacs P.

Expert Rev Clin Pharmacol. 2012 Jul;5(4):373-88. doi: 10.1586/ecp.12.26. Review.

PMID:
22943117
4.

Influence of alitretinoin on the pharmacokinetics of the oral contraceptive ethinyl estradiol/norgestimate.

Schmitt-Hoffmann AH, Roos B, Sauer J, Schleimer M, Schoetzau A, Leese PT, Weidekamm E, Maares J.

Clin Exp Dermatol. 2011 Apr;36 Suppl 2:4-11. doi: 10.1111/j.1365-2230.2011.04031.x.

PMID:
21443598
5.

Neurocognitive effects of brivaracetam, levetiracetam, and lorazepam.

Meador KJ, Gevins A, Leese PT, Otoul C, Loring DW.

Epilepsia. 2011 Feb;52(2):264-72. doi: 10.1111/j.1528-1167.2010.02746.x. Epub 2010 Sep 30.

6.

Population PK-PD model for Fc-osteoprotegerin in healthy postmenopausal women.

Zierhut ML, Gastonguay MR, Martin SW, Vicini P, Bekker PJ, Holloway D, Leese PT, Peterson MC.

J Pharmacokinet Pharmacodyn. 2008 Aug;35(4):379-99. doi: 10.1007/s10928-008-9093-5. Epub 2008 Jul 17.

PMID:
18633695
7.

Rapid and reversible modulation of platelet function in man by a novel P2Y(12) ADP-receptor antagonist, INS50589.

Johnson FL, Boyer JL, Leese PT, Crean C, Krishnamoorthy R, Durham T, Fox AW, Kellerman DJ.

Platelets. 2007 Aug;18(5):346-56.

PMID:
17654304
8.

The effects of supratherapeutic doses of duloxetine on blood pressure and pulse rate.

Derby MA, Zhang L, Chappell JC, Gonzales CR, Callaghan JT, Leibowitz M, Ereshefsky L, Hoelscher D, Leese PT, Mitchell MI.

J Cardiovasc Pharmacol. 2007 Jun;49(6):384-93.

PMID:
17577103
9.

QT effects of duloxetine at supratherapeutic doses: a placebo and positive controlled study.

Zhang L, Chappell J, Gonzales CR, Small D, Knadler MP, Callaghan JT, Francis JL, Desaiah D, Leibowitz M, Ereshefsky L, Hoelscher D, Leese PT, Derby M.

J Cardiovasc Pharmacol. 2007 Mar;49(3):146-53.

PMID:
17414226
10.

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. 2004.

Bekker PJ, Holloway DL, Rasmussen AS, Murphy R, Martin SW, Leese PT, Holmes GB, Dunstan CR, DePaoli AM.

J Bone Miner Res. 2005 Dec;20(12):2275-82. No abstract available.

11.

Clinical safety and efficacy of a powdered Hepatitis B nucleic acid vaccine delivered to the epidermis by a commercial prototype device.

Roberts LK, Barr LJ, Fuller DH, McMahon CW, Leese PT, Jones S.

Vaccine. 2005 Sep 23;23(40):4867-78.

PMID:
15985318
12.

Safety and pharmacokinetic evaluation of intravenous vaccinia immune globulin in healthy volunteers.

Hopkins RJ, Kramer WG, Blackwelder WC, Ashtekar M, Hague L, Winker-La Roche SD, Berezuk G, Smith D, Leese PT.

Clin Infect Dis. 2004 Sep 15;39(6):759-66. Epub 2004 Aug 23.

PMID:
15472804
13.

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women.

Bekker PJ, Holloway DL, Rasmussen AS, Murphy R, Martin SW, Leese PT, Holmes GB, Dunstan CR, DePaoli AM.

J Bone Miner Res. 2004 Jul;19(7):1059-66. Epub 2004 Mar 1.

14.
15.

Valdecoxib does not impair platelet function.

Leese PT, Talwalker S, Kent JD, Recker DP.

Am J Emerg Med. 2002 Jul;20(4):275-81.

PMID:
12098171
16.

Dosing in heavy-weight/obese patients with the LMWH, tinzaparin: a pharmacodynamic study.

Hainer JW, Barrett JS, Assaid CA, Fossler MJ, Cox DS, Leathers T, Leese PT.

Thromb Haemost. 2002 May;87(5):817-23.

PMID:
12038783
17.

The pharmacokinetics of sumatriptan when administered with clarithromycin in healthy volunteers.

Moore KH, Leese PT, McNeal S, Gray P, O'Quinn S, Bye C, Sale M.

Clin Ther. 2002 Apr;24(4):583-94.

PMID:
12017403
18.

Pharmacokinetics of norelgestromin and ethinyl estradiol delivered by a contraceptive patch (Ortho Evra/Evra) under conditions of heat, humidity, and exercise.

Abrams LS, Skee DM, Natarajan J, Wong FA, Leese PT, Creasy GW, Shangold MM.

J Clin Pharmacol. 2001 Dec;41(12):1301-9.

PMID:
11762557
19.

Pharmacokinetics of norelgestromin and ethinyl estradiol from two consecutive contraceptive patches.

Abrams LS, Skee DM, Wong FA, Anderson NJ, Leese PT.

J Clin Pharmacol. 2001 Nov;41(11):1232-7.

PMID:
11697756
20.

The effect of a single dose of osteoprotegerin in postmenopausal women.

Bekker PJ, Holloway D, Nakanishi A, Arrighi M, Leese PT, Dunstan CR.

J Bone Miner Res. 2001 Feb;16(2):348-60.

21.

Randomized safety studies of intravenous perflubron emulsion. II. Effects on immune function in healthy volunteers.

Noveck RJ, Shannon EJ, Leese PT, Shorr JS, Flaim KE, Keipert PE, Woods CM.

Anesth Analg. 2000 Oct;91(4):812-22.

PMID:
11004031
22.

Randomized safety studies of intravenous perflubron emulsion. I. Effects on coagulation function in healthy volunteers.

Leese PT, Noveck RJ, Shorr JS, Woods CM, Flaim KE, Keipert PE.

Anesth Analg. 2000 Oct;91(4):804-11.

PMID:
11004030
23.

Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial.

Leese PT, Hubbard RC, Karim A, Isakson PC, Yu SS, Geis GS.

J Clin Pharmacol. 2000 Feb;40(2):124-32.

PMID:
10664917
24.

Pharmacokinetics of a once-daily oral dose of moxifloxacin (Bay 12-8039), a new enantiomerically pure 8-methoxy quinolone.

Sullivan JT, Woodruff M, Lettieri J, Agarwal V, Krol GJ, Leese PT, Watson S, Heller AH.

Antimicrob Agents Chemother. 1999 Nov;43(11):2793-7.

25.

Pharmacokinetics of intravenous amiodarone in patients with impaired left ventricular function.

Vadiei K, O'Rangers EA, Klamerus KJ, Kluger J, Kazierad DJ, Leese PT, Chow MS, Zimmerman JJ.

J Clin Pharmacol. 1996 Aug;36(8):720-7. Erratum in: J Clin Pharmacol 1997 Jan;37(1):73-5.

PMID:
8877676
26.

The pharmacokinetic-pharmacodynamic (Digit Symbol Substitution Test) relationship of flumazenil in a midazolam steady-state model in healthy volunteers.

Zhi J, Massarella JW, Melia AT, Teller SB, Schmitt-Muskus J, Crews T, Oldfield N, Erb RJ, Leese PT, Patel IH.

Clin Pharmacol Ther. 1994 Nov;56(5):530-6.

PMID:
7955817
27.

Efficacy and safety of cetirizine therapy in perennial allergic rhinitis.

Mansmann HC Jr, Altman RA, Berman BA, Buchman E, Dockhorn RJ, Leese PT, Love SJ, Middleton E Jr.

Ann Allergy. 1992 Apr;68(4):348-53.

PMID:
1348405
28.

A phase I clinical trial with gadodiamide injection, a nonionic magnetic resonance imaging enhancement agent.

VanWagoner M, O'Toole M, Worah D, Leese PT, Quay SC.

Invest Radiol. 1991 Nov;26(11):980-6.

PMID:
1743922
29.

Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis.

Falliers CJ, Brandon ML, Buchman E, Connell JT, Dockhorn R, Leese PT, Miller J, Wasserman SI, Zeterberg JM, Altman R, et al.

Ann Allergy. 1991 Mar;66(3):257-62.

PMID:
1672494
30.

Hepatobiliary MR imaging: first human experience with MnDPDP.

Lim KO, Stark DD, Leese PT, Pfefferbaum A, Rocklage SM, Quay SC.

Radiology. 1991 Jan;178(1):79-82.

PMID:
1898539
31.

Pharmacokinetic and pharmacodynamic comparison of an osmotic release oral metoprolol tablet and the metoprolol conventional tablet.

Feliciano NR, Bouvet AA, Redalieu E, Castellana J, Luders RC, Schwartz DJ, Shum L, Zak S, Arnold JD, Leese PT.

Am Heart J. 1990 Aug;120(2):483-9.

PMID:
2382633
32.

Safety and tolerability of single intravenous doses of T cell modulatory peptide (TCMP-80) in healthy volunteers.

Eldon MA, Smith RA, Leese PT, Daigle AE, Katz DV, Richieri SP.

J Clin Pharmacol. 1990 Apr;30(4):352-7.

PMID:
2140370
33.

Ferrioxamine as a magnetic resonance contrast agent. Preclinical studies and phase I and II human clinical trials.

Worah D, Berger AE, Burnett KR, Cockrill HH, Kanal E, Kendall C, Leese PT, Lyons KP, Ross E, Wolf GL, et al.

Invest Radiol. 1988 Sep;23 Suppl 1:S281-5.

PMID:
3058632
34.

Effect of cetamolol on epinephrine-induced hypokalemia.

Klausner MA, Irwin C, Mullane JF, Shand DG, Leese PT, Arnold JD, Wollberg W, Wagner NB, Wagner GS.

J Clin Pharmacol. 1988 Aug;28(8):751-6.

PMID:
2905711
35.

Pharmacokinetics of leucovorin calcium after intravenous, intramuscular, and oral administration.

McGuire BW, Sia LL, Leese PT, Gutierrez ML, Stokstad EL.

Clin Pharm. 1988 Jan;7(1):52-8.

PMID:
3257913
36.

The development of specific IgG4 after immunotherapy with standardized extracts.

Harris NS, Rock HS, Leese PT.

N Engl Reg Allergy Proc. 1987 Nov-Dec;8(6):429-35.

PMID:
3325819
37.

Etintidine-theophylline interaction study in humans.

Huang SM, Weintraub HS, Marriott TB, Marinan B, Abels R, Leese PT.

Biopharm Drug Dispos. 1987 Nov-Dec;8(6):561-9.

PMID:
2892545
38.

Bioavailability and pharmacokinetics of a new sustained-release potassium chloride tablet.

Betlach CJ, Arnold JD, Frost RW, Leese PT, Gonzalez MA.

Pharm Res. 1987 Oct;4(5):409-11.

PMID:
3508550
39.

Human pharmacologic trials with iohexol.

Aakhus T, Dahlström K, Shaw DD, Leese PT, March L.

Acta Radiol Suppl. 1983;366:20-2.

PMID:
6433655

Supplemental Content

Loading ...
Support Center