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Items: 1 to 50 of 54

1.

Ly49D-mediated ITAM signaling in immature thymocytes impairs development by bypassing the pre-TCR checkpoint.

Merck E, Lees RK, Voyle RB, Held W, MacDonald HR.

J Immunol. 2011 Jul 1;187(1):110-7. doi: 10.4049/jimmunol.1002755. Epub 2011 Jun 1.

2.

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts.

Fortner KA, Lees RK, MacDonald HR, Budd RC.

Int Immunol. 2011 Feb;23(2):75-88. doi: 10.1093/intimm/dxq466. Epub 2011 Jan 25.

4.

Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D.

Voyle RB, Beermann F, Lees RK, Schümann J, Zimmer J, Held W, MacDonald HR.

J Exp Med. 2003 Apr 7;197(7):919-25.

5.

A role for CD147 in thymic development.

Renno T, Wilson A, Dunkel C, Coste I, Maisnier-Patin K, Benoit de Coignac A, Aubry JP, Lees RK, Bonnefoy JY, MacDonald HR, Gauchat JF.

J Immunol. 2002 May 15;168(10):4946-50.

7.
8.

Quantitative impact of thymic clonal deletion on the T cell repertoire.

van Meerwijk JP, Marguerat S, Lees RK, Germain RN, Fowlkes BJ, MacDonald HR.

J Exp Med. 1997 Feb 3;185(3):377-83.

9.

Quantitation of endogenous mouse mammary tumor virus superantigen expression by lymphocyte subsets.

Waanders GA, Lees RK, Held W, MacDonald HR.

Eur J Immunol. 1995 Sep;25(9):2632-7.

PMID:
7589137
10.

CD4/CD8 lineage commitment in T cell receptor transgenic mice: evidence for precommitment of CD4+ CD8+ thymocytes.

Crompton T, Hefti H, Lees RK, Pircher H, MacDonald HR.

Semin Immunol. 1994 Aug;6(4):249-56. Review.

PMID:
8000034
11.

Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages.

Crompton T, Lees RK, Pircher H, MacDonald HR.

Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8982-6.

12.

Clonal anergy to staphylococcal enterotoxin B in vivo: selective effects on T cell subsets and lymphokines.

Baschieri S, Lees RK, Lussow AR, MacDonald HR.

Eur J Immunol. 1993 Oct;23(10):2661-6.

PMID:
8104798
13.

Peripheral T-cell reactivity to bacterial superantigens in vivo: the response/anergy paradox.

MacDonald HR, Lees RK, Baschieri S, Herrmann T, Lussow AR.

Immunol Rev. 1993 Jun;133:105-17. Review. No abstract available.

PMID:
8225363
14.

Exogenous and endogenous mouse mammary tumor virus superantigens.

Acha-Orbea H, Held W, Waanders GA, Shakhov AN, Scarpellino L, Lees RK, MacDonald HR.

Immunol Rev. 1993 Feb;131:5-25. Review. No abstract available.

PMID:
8387457
15.

In vivo responses of CD4+ and CD8+ cells to bacterial superantigens.

Herrmann T, Baschieri S, Lees RK, MacDonald HR.

Eur J Immunol. 1992 Jul;22(7):1935-8.

PMID:
1623932
16.
17.

Does negative selection involve accumulation of self-reactive thymocytes in thymic rosettes?

Shortman K, Vremec D, Lees RK, MacDonald HR.

Immunol Lett. 1991 Jun;28(3):201-5.

PMID:
1885217
18.

Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells.

Speiser DE, Brändle R, Lees RK, Schneider R, Zinkernagel RM, MacDonald HR.

Int Immunol. 1991 Feb;3(2):127-34.

PMID:
1709047
19.

CD8+ T cells respond clonally to Mls-1a-encoded determinants.

MacDonald HR, Lees RK, Chvatchko Y.

J Exp Med. 1990 Apr 1;171(4):1381-6.

20.

Programmed death of autoreactive thymocytes.

MacDonald HR, Lees RK.

Nature. 1990 Feb 15;343(6259):642-4.

PMID:
2304535
21.

Selective expression of V delta 6 genes by B2A2- CD4- CD8- T cell receptor gamma/delta thymocytes.

Miescher GC, Liao NS, Lees RK, MacDonald HR, Raulet DH.

Eur J Immunol. 1990 Jan;20(1):41-5.

PMID:
2137782
22.

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.

Speiser DE, Lees RK, Hengartner H, Zinkernagel RM, MacDonald HR.

J Exp Med. 1989 Dec 1;170(6):2165-70.

23.

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

Schneider R, Lees RK, Pedrazzini T, Zinkernagel RM, Hengartner H, MacDonald HR.

J Exp Med. 1989 Jun 1;169(6):2149-58.

24.

T-cell reactivity and tolerance to Mlsa-encoded antigens.

MacDonald HR, Glasebrook AL, Schneider R, Lees RK, Pircher H, Pedrazzini T, Kanagawa O, Nicolas JF, Howe RC, Zinkernagel RM, et al.

Immunol Rev. 1989 Feb;107:89-108. Review. No abstract available.

PMID:
2522087
25.

Positive selection of CD4+ thymocytes controlled by MHC class II gene products.

MacDonald HR, Lees RK, Schneider R, Zinkernagel RM, Hengartner H.

Nature. 1988 Dec 1;336(6198):471-3.

PMID:
3264054
26.

T-cell lineages, repertoire selection and tolerance induction.

MacDonald HR, Howe RC, Pedrazzini T, Lees RK, Budd RC, Schneider R, Liao NS, Zinkernagel RM, Louis JA, Raulet DH, et al.

Immunol Rev. 1988 Aug;104:157-82. Review. No abstract available.

PMID:
3049315
27.

CD3-associated alpha/beta and gamma/delta heterodimeric receptors are expressed by distinct populations of CD4- CD8- thymocytes.

Miescher GC, Howe RC, Lees RK, MacDonald HR.

J Immunol. 1988 Mar 15;140(6):1779-82.

PMID:
2964483
28.

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens.

MacDonald HR, Schneider R, Lees RK, Howe RC, Acha-Orbea H, Festenstein H, Zinkernagel RM, Hengartner H.

Nature. 1988 Mar 3;332(6159):40-5. Review.

PMID:
3126397
29.

Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

Budd RC, Miescher GC, Howe RC, Lees RK, Bron C, MacDonald HR.

J Exp Med. 1987 Aug 1;166(2):577-82.

30.

T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire.

MacDonald HR, Lees RK, Bron C, Sordat B, Miescher G.

J Exp Med. 1987 Jul 1;166(1):195-209.

31.

Abnormal expression of T cell receptor genes in Lyt-2- L3T4- lymphocytes of lpr mice: comparison with normal immature thymocytes.

Miescher GC, Budd RC, Lees RK, MacDonald HR.

J Immunol. 1987 Mar 15;138(6):1959-67.

PMID:
3102607
32.

Abnormal distribution of T cell subsets in athymic mice.

MacDonald HR, Blanc C, Lees RK, Sordat B.

J Immunol. 1986 Jun 15;136(12):4337-9. No abstract available.

PMID:
3486898
34.

Mutant EL-4 thymoma cells polyclonally activate murine and human B cells via direct cell interaction.

Zubler RH, Erard F, Lees RK, Van Laer M, Mingari C, Moretta L, MacDonald HR.

J Immunol. 1985 Jun;134(6):3662-8.

PMID:
3886789
35.

Frequency and specificity of precursors of interleukin 2-producing cells in nude mice.

MacDonald HR, Lees RK.

J Immunol. 1984 Feb;132(2):605-10.

PMID:
6197467
36.

Alloreactive cytolytic T lymphocyte precursor cells in aged C57Bl/6 nu/nu mice: frequency and cell surface phenotype.

Maryanski JL, MacDonald HR, Lees RK, Sordat B, Cerottini JC.

Exp Cell Biol. 1984;52(1-2):21-4. No abstract available.

PMID:
6607855
37.

Development and localization of 'T-like' cells in the nude mouse.

Bamat J, Sordat B, Lees RK, Zaech P, Ceredig R, MacDonald HR.

Exp Cell Biol. 1984;52(1-2):25-9. No abstract available.

PMID:
6141961
38.

Interleukin-2 production by lymphoid cells from nude mice. A comparison of bulk culture and limiting dilution analysis.

Lees RK, MacDonald HR, Glasebrook AL, Sordat B.

Exp Cell Biol. 1984;52(1-2):12-6. No abstract available.

PMID:
6141958
39.

Interleukin 2 production by lymphoid cells from congenitally athymic (nu/nu) mice.

MacDonald HR, Lees RK, Glasebrook AL, Sordat B.

J Immunol. 1982 Aug;129(2):521-5.

PMID:
6123534
40.
42.
43.

The multicellular spheroid as a model tumor allograft. III. Morphological and kinetic analysis of spheroid infiltration and destruction.

Sordat B, MacDonald HR, Lees RK.

Transplantation. 1980 Feb;29(2):103-12. No abstract available.

PMID:
7355480
44.

Quantitative approaches to the assessment of cell-mediated immune responses to solid tumor allografts.

MacDonald HR, Lees RK, Howell RL.

Transplant Proc. 1978 Jun;10(2):339-42. No abstract available.

PMID:
97826
45.
46.

Regulation of the immune response. XII. Targets for suppressor cell activity in an in vitro cell-mediated immune response.

Sinclair NR, Lees RK, Missiuna PC, Vichos EE.

Cell Immunol. 1976 Dec;27(2):163-70. No abstract available.

PMID:
1009582
47.

Regulation of the immune response. XI-Cell-mediated feedback of an in vitro cell-mediated immune response.

Sinclair NR, Lees RK, Wheeler ME, Vichos EE, Fung FY.

Cell Immunol. 1976 Dec;27(2):153-62. No abstract available.

PMID:
1009581
48.
49.
50.

Regulation of the immune response. VIII. Characteristics of antibody-mediated suppression of an in vitro cell-mediated immune response.

Sinclair NR, Lees RK, Fagan G, Birnbaum A.

Cell Immunol. 1975 Apr;16(2):330-47. No abstract available.

PMID:
803878

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