Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 356

1.

Sodium pumps, ouabain and aldosterone in the brain: A neuromodulatory pathway underlying salt-sensitive hypertension and heart failure.

Leenen FHH, Wang HW, Hamlyn JM.

Cell Calcium. 2020 Mar;86:102151. doi: 10.1016/j.ceca.2019.102151. Epub 2019 Dec 17.

PMID:
31954234
2.

Effect of exercise training on the FNDC5/BDNF pathway in spontaneously hypertensive rats.

Wang T, Maltez MT, Lee HW, Ahmad M, Wang HW, Leenen FHH.

Physiol Rep. 2019 Dec;7(24):e14323. doi: 10.14814/phy2.14323.

3.

Angiotensin II modulates brain-derived neurotrophic factor expression in the brain and adrenal.

Wang HW, Lu J, Liang W, Leenen FHH.

Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129505. doi: 10.1016/j.bbagen.2019.129505. Epub 2019 Dec 19. No abstract available.

PMID:
31863813
4.

Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats.

Najjar F, Ahmad M, Lagace D, Leenen FHH.

Neuroscience. 2019 Sep 1;415:201-214. doi: 10.1016/j.neuroscience.2019.07.017. Epub 2019 Jul 24.

PMID:
31351141
5.

Inhibition of inflammation by minocycline improves heart failure and depression-like behaviour in rats after myocardial infarction.

Wang HW, Ahmad M, Jadayel R, Najjar F, Lagace D, Leenen FHH.

PLoS One. 2019 Jun 24;14(6):e0217437. doi: 10.1371/journal.pone.0217437. eCollection 2019.

6.

Use of Directly Observed Therapy to Assess Treatment Adherence in Patients With Apparent Treatment-Resistant Hypertension.

Ruzicka M, Leenen FHH, Ramsay T, Bugeja A, Edwards C, McCormick B, Hiremath S.

JAMA Intern Med. 2019 Jun 17. doi: 10.1001/jamainternmed.2019.1455. [Epub ahead of print] No abstract available.

PMID:
31206124
7.

Specific Inhibition of Brain Angiotensin III Formation as a New Strategy for Prevention of Heart Failure After Myocardial Infarction.

Leenen FHH, Ahmad M, Marc Y, Llorens-Cortes C.

J Cardiovasc Pharmacol. 2019 Feb;73(2):82-91. doi: 10.1097/FJC.0000000000000638.

PMID:
30531435
8.

Effects of exercise training and TrkB blockade on cardiac function and BDNF-TrkB signaling postmyocardial infarction in rats.

Lee HW, Ahmad M, Weldrick JJ, Wang HW, Burgon PG, Leenen FHH.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1821-H1834. doi: 10.1152/ajpheart.00245.2018. Epub 2018 Oct 12.

9.

Sex differences in depression-like behavior and neuroinflammation in rats post-MI: role of estrogens.

Najjar F, Ahmad M, Lagace D, Leenen FHH.

Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1159-H1173. doi: 10.1152/ajpheart.00615.2017. Epub 2018 Jul 27.

10.

Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats.

Lu J, Wang HW, Ahmad M, Keshtkar-Jahromi M, Blaustein MP, Hamlyn JM, Leenen FHH.

Cardiovasc Res. 2018 Feb 1;114(2):233-246. doi: 10.1093/cvr/cvx214.

11.

Reply.

Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, de Leeuw PW, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B.

J Hypertens. 2017 Nov;35(11):2327-2328. doi: 10.1097/HJH.0000000000001526. No abstract available.

12.

Update on angiotensin II: new endocrine connections between the brain, adrenal glands and the cardiovascular system.

Leenen FHH, Blaustein MP, Hamlyn JM.

Endocr Connect. 2017 Oct;6(7):R131-R145. doi: 10.1530/EC-17-0161. Epub 2017 Aug 30. Review.

13.

Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart.

Abdul-Ghani M, Suen C, Jiang B, Deng Y, Weldrick JJ, Putinski C, Brunette S, Fernando P, Lee TT, Flynn P, Leenen FHH, Burgon PG, Stewart DJ, Megeney LA.

Cell Res. 2017 Oct;27(10):1195-1215. doi: 10.1038/cr.2017.87. Epub 2017 Aug 8.

14.

Expertise: no longer a sine qua non for guideline authors?

Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B, de Leeuw PW.

J Hypertens. 2017 Aug;35(8):1564-1566. doi: 10.1097/HJH.0000000000001435.

15.

Expertise: No Longer a Sine Qua Non for Guideline Authors?

Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B.

Hypertension. 2017 Aug;70(2):235-237. doi: 10.1161/HYPERTENSIONAHA.117.09470. Epub 2017 Jun 26. No abstract available.

16.

Effects of exercise training on brain-derived neurotrophic factor in skeletal muscle and heart of rats post myocardial infarction.

Lee HW, Ahmad M, Wang HW, Leenen FH.

Exp Physiol. 2017 Mar 1;102(3):314-328. doi: 10.1113/EP086049.

17.

On-treatment blood pressures of older hypertensive patients in Canada: implications for Systolic blood PRessure INtervention Trial.

Fodor JG, Baker P, Chen L, Leenen FH.

J Hypertens. 2017 Mar;35(3):621-626. doi: 10.1097/HJH.0000000000001184.

PMID:
27926691
18.

Pivotal role of α2 Na+ pumps and their high affinity ouabain binding site in cardiovascular health and disease.

Blaustein MP, Chen L, Hamlyn JM, Leenen FH, Lingrel JB, Wier WG, Zhang J.

J Physiol. 2016 Nov 1;594(21):6079-6103. doi: 10.1113/JP272419. Epub 2016 Jul 31. Review.

19.

Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension.

Wang HW, Huang BS, White RA, Chen A, Ahmad M, Leenen FH.

Neuroscience. 2016 Aug 4;329:112-21. doi: 10.1016/j.neuroscience.2016.04.050. Epub 2016 May 6.

PMID:
27163380
20.

Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats.

Wang HW, Huang BS, Chen A, Ahmad M, White RA, Leenen FH.

Neuroscience. 2016 Feb 9;314:90-105. doi: 10.1016/j.neuroscience.2015.11.055. Epub 2015 Nov 30.

PMID:
26656220
21.
22.

Neuroendocrine humoral and vascular components in the pressor pathway for brain angiotensin II: a new axis in long term blood pressure control.

Hamlyn JM, Linde CI, Gao J, Huang BS, Golovina VA, Blaustein MP, Leenen FH.

PLoS One. 2014 Oct 2;9(9):e108916. doi: 10.1371/journal.pone.0108916. eCollection 2014.

23.

Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade.

Rafatian N, Westcott KV, White RA, Leenen FH.

Am J Physiol Regul Integr Comp Physiol. 2014 Oct 1;307(7):R879-87. doi: 10.1152/ajpregu.00075.2014. Epub 2014 Aug 6.

24.

Knockdown of mineralocorticoid or angiotensin II type 1 receptor gene expression in the paraventricular nucleus prevents angiotensin II hypertension in rats.

Chen A, Huang BS, Wang HW, Ahmad M, Leenen FH.

J Physiol. 2014 Aug 15;592(16):3523-36. doi: 10.1113/jphysiol.2014.275560. Epub 2014 Jun 27.

25.

Mineralocorticoid and AT1 receptors in the paraventricular nucleus contribute to sympathetic hyperactivity and cardiac dysfunction in rats post myocardial infarct.

Huang BS, Chen A, Ahmad M, Wang HW, Leenen FH.

J Physiol. 2014 Aug 1;592(15):3273-86. doi: 10.1113/jphysiol.2014.276584. Epub 2014 Jun 20.

26.

Actions of circulating angiotensin II and aldosterone in the brain contributing to hypertension.

Leenen FH.

Am J Hypertens. 2014 Aug;27(8):1024-32. doi: 10.1093/ajh/hpu066. Epub 2014 Apr 17. Review.

PMID:
24742639
27.

Adherence to blood pressure-lowering drugs and resistant hypertension: should trial of direct observation therapy be part of preassessment for renal denervation?

Ruzicka M, McCormick B, Leenen FH, Froeschl M, Hiremath S.

Can J Cardiol. 2013 Dec;29(12):1741.e1-3. doi: 10.1016/j.cjca.2013.07.678. Epub 2013 Oct 16.

PMID:
24140076
28.

Cardiac sympathetic innervation and PGP9.5 expression by cardiomyocytes after myocardial infarction: effects of central MR blockade.

Drobysheva A, Ahmad M, White R, Wang HW, Leenen FH.

Am J Physiol Heart Circ Physiol. 2013 Dec;305(12):H1817-29. doi: 10.1152/ajpheart.00445.2013. Epub 2013 Oct 11.

29.

Role of renin-angiotensin system in activation of macrophages by modified lipoproteins.

Rafatian N, Milne RW, Leenen FH, Whitman SC.

Am J Physiol Heart Circ Physiol. 2013 Nov 1;305(9):H1309-20. doi: 10.1152/ajpheart.00826.2012. Epub 2013 Aug 30.

30.

Cathepsin G deficiency decreases complexity of atherosclerotic lesions in apolipoprotein E-deficient mice.

Rafatian N, Karunakaran D, Rayner KJ, Leenen FH, Milne RW, Whitman SC.

Am J Physiol Heart Circ Physiol. 2013 Oct 15;305(8):H1141-8. doi: 10.1152/ajpheart.00618.2012. Epub 2013 Aug 9.

31.

Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.

Huang BS, White RA, Ahmad M, Leenen FH.

Hypertension. 2013 Sep;62(3):564-71. doi: 10.1161/HYPERTENSIONAHA.113.01557. Epub 2013 Jul 15.

PMID:
23856493
32.

Role of angiotensin II type 1 receptors in the subfornical organ in the pressor responses to central sodium in rats.

Tiruneh MA, Huang BS, Leenen FH.

Brain Res. 2013 Aug 21;1527:79-86. doi: 10.1016/j.brainres.2013.06.028. Epub 2013 Jun 28.

PMID:
23816375
33.

Comparative effectiveness of monotherapies and combination therapies for patients with hypertension: protocol for a systematic review with network meta-analyses.

Hutton B, Tetzlaff J, Yazdi F, Thielman J, Kanji S, Fergusson D, Bjerre L, Mills E, Thorlund K, Tricco A, Straus S, Moher D, Leenen FH.

Syst Rev. 2013 Jun 28;2:44. doi: 10.1186/2046-4053-2-44.

34.

Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.

Gabor A, Leenen FH.

Hypertension. 2013 May;61(5):1083-90. doi: 10.1161/HYPERTENSIONAHA.111.00797. Epub 2013 Mar 18.

PMID:
23509081
35.

Epicardial adipose tissue and cardiometabolic risk factors in overweight and obese children and adolescents.

Schusterova I, Leenen FH, Jurko A, Sabol F, Takacova J.

Pediatr Obes. 2014 Feb;9(1):63-70. doi: 10.1111/j.2047-6310.2012.00134.x. Epub 2013 Mar 18.

PMID:
23504985
36.

Inhibition of brain angiotensin III attenuates sympathetic hyperactivity and cardiac dysfunction in rats post-myocardial infarction.

Huang BS, Ahmad M, White RA, Marc Y, Llorens-Cortes C, Leenen FH.

Cardiovasc Res. 2013 Mar 1;97(3):424-31. doi: 10.1093/cvr/cvs420. Epub 2012 Dec 19.

PMID:
23257024
37.

Do high doses of AT(1)-receptor blockers attenuate central sympathetic outflow in humans with chronic heart failure?

Ruzicka M, Floras JS, McReynolds AJ, Coletta E, Haddad H, Davies R, Leenen FH.

Clin Sci (Lond). 2013 May;124(9):589-95. doi: 10.1042/CS20120437.

PMID:
23163825
38.

A cross-national comparative study of blood pressure levels and hypertension prevalence in Canada and Hungary.

Steiner S, Helis E, Chen L, Turton P, Leenen FH, Sonkodi S, Sonkodi B, D'Angelo MS, Fodor JG.

J Hypertens. 2012 Nov;30(11):2105-11. doi: 10.1097/HJH.0b013e3283589ec3.

PMID:
23027179
39.

Cardioprotective brain mechanisms.

Leenen FH, Tuana BS.

Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1749-50. doi: 10.1161/ATVBAHA.112.252627. No abstract available.

PMID:
22815337
40.

Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.

Van Huysse JW, Amin MS, Yang B, Leenen FH.

Hypertension. 2012 Sep;60(3):691-6. doi: 10.1161/HYPERTENSIONAHA.112.193045. Epub 2012 Jul 16.

41.

Central neuromodulatory pathways regulating sympathetic activity in hypertension.

Gabor A, Leenen FH.

J Appl Physiol (1985). 2012 Oct 15;113(8):1294-303. doi: 10.1152/japplphysiol.00553.2012. Epub 2012 Jul 5. Review.

42.

Central sympathetic inhibition by mineralocorticoid receptor but not angiotensin II type 1 receptor blockade: are prescribed doses too low?

Leenen FH, Ruzicka M, Floras JS.

Hypertension. 2012 Aug;60(2):278-80. doi: 10.1161/HYPERTENSIONAHA.112.197012. Epub 2012 Jun 25. No abstract available.

PMID:
22733463
43.

Possible role of brain salt-inducible kinase 1 in responses to central sodium in Dahl rats.

Huang BS, White RA, Leenen FH.

Am J Physiol Regul Integr Comp Physiol. 2012 Jul 15;303(2):R236-45. doi: 10.1152/ajpregu.00381.2011. Epub 2012 May 30.

44.

The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy.

Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS.

FASEB J. 2012 Jun;26(6):2569-79. doi: 10.1096/fj.11-203174. Epub 2012 Mar 7.

PMID:
22403008
45.

Cardiovascular effects of angiotensin II and glutamate in the PVN of Dahl salt-sensitive rats.

Gabor A, Leenen FH.

Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1.

PMID:
22356885
46.

Central infusion of aliskiren prevents sympathetic hyperactivity and hypertension in Dahl salt-sensitive rats on high salt intake.

Huang BS, White RA, Bi L, Leenen FH.

Am J Physiol Regul Integr Comp Physiol. 2012 Apr;302(7):R825-32. doi: 10.1152/ajpregu.00368.2011. Epub 2012 Jan 18.

47.

Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum.

Nader M, Westendorp B, Hawari O, Salih M, Stewart AF, Leenen FH, Tuana BS.

Am J Physiol Heart Circ Physiol. 2012 Mar 1;302(5):H1138-45. doi: 10.1152/ajpheart.00872.2011. Epub 2011 Dec 16.

48.

How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension.

Blaustein MP, Leenen FH, Chen L, Golovina VA, Hamlyn JM, Pallone TL, Van Huysse JW, Zhang J, Wier WG.

Am J Physiol Heart Circ Physiol. 2012 Mar 1;302(5):H1031-49. doi: 10.1152/ajpheart.00899.2011. Epub 2011 Nov 4. Review.

49.

Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone.

Huang BS, Zheng H, Tan J, Patel KP, Leenen FH.

Exp Physiol. 2011 Oct;96(10):1028-38. doi: 10.1113/expphysiol.2011.059840. Epub 2011 Aug 8.

50.

Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats.

Gabor A, Leenen FH.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1338-49. doi: 10.1152/ajpregu.00246.2011. Epub 2011 Jul 27.

Supplemental Content

Loading ...
Support Center