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Items: 1 to 50 of 267

1.

Intrastriatal gradient analyses of 18F-FDOPA PET scans for differentiation of Parkinsonian disorders.

Stormezand GN, Chaves LT, Vállez García D, Doorduin J, De Jong BM, Leenders KL, Kremer BPH, Dierckx RAJO.

Neuroimage Clin. 2020 Jan 3;25:102161. doi: 10.1016/j.nicl.2019.102161. [Epub ahead of print]

2.

Abnormal pattern of brain glucose metabolism in Parkinson's disease: replication in three European cohorts.

Meles SK, Renken RJ, Pagani M, Teune LK, Arnaldi D, Morbelli S, Nobili F, van Laar T, Obeso JA, Rodríguez-Oroz MC, Leenders KL.

Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):437-450. doi: 10.1007/s00259-019-04570-7. Epub 2019 Nov 25.

3.

Functional impact of subthalamotomy by magnetic resonance-guided focused ultrasound in Parkinson's disease: a hybrid PET/MR study of resting-state brain metabolism.

Rodriguez-Rojas R, Pineda-Pardo JA, Martinez-Fernandez R, Kogan RV, Sanchez-Catasus CA, Del Alamo M, Hernández F, García-Cañamaque L, Leenders KL, Obeso JA.

Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):425-436. doi: 10.1007/s00259-019-04497-z. Epub 2019 Nov 8.

PMID:
31705173
4.

Factors affecting the harmonization of disease-related metabolic brain pattern expression quantification in [18F]FDG-PET (PETMETPAT).

Kogan RV, de Jong BA, Renken RJ, Meles SK, van Snick PJH, Golla S, Rijnsdorp S, Perani D, Leenders KL, Boellaard R; JPND-PETMETPAT Working Group.

Alzheimers Dement (Amst). 2019 Jun 22;11:472-482. doi: 10.1016/j.dadm.2019.04.002. eCollection 2019 Dec.

5.

Scaled Subprofile Modeling and Convolutional Neural Networks for the Identification of Parkinson's Disease in 3D Nuclear Imaging Data.

Manzanera OM, Meles SK, Leenders KL, Renken RJ, Pagani M, Arnaldi D, Nobili F, Obeso J, Oroz MR, Morbelli S, Maurits NM.

Int J Neural Syst. 2019 Nov;29(9):1950010. doi: 10.1142/S0129065719500102. Epub 2019 Mar 3.

PMID:
31046514
6.

Brain Glucose Metabolism Heterogeneity in Idiopathic REM Sleep Behavior Disorder and in Parkinson's Disease.

Arnaldi D, Meles SK, Giuliani A, Morbelli S, Renken RJ, Janzen A, Mayer G, Jonsson C, Oertel WH, Nobili F, Leenders KL, Pagani M; REMPET Study Group.

J Parkinsons Dis. 2019;9(1):229-239. doi: 10.3233/JPD-181468.

PMID:
30741687
7.

The cerebral metabolic topography of spinocerebellar ataxia type 3.

Meles SK, Kok JG, De Jong BM, Renken RJ, de Vries JJ, Spikman JM, Ziengs AL, Willemsen ATM, van der Horn HJ, Leenders KL, Kremer HPH.

Neuroimage Clin. 2018 Mar 29;19:90-97. doi: 10.1016/j.nicl.2018.03.038. eCollection 2018.

8.

The Metabolic Pattern of Idiopathic REM Sleep Behavior Disorder Reflects Early-Stage Parkinson Disease.

Meles SK, Renken RJ, Janzen A, Vadasz D, Pagani M, Arnaldi D, Morbelli S, Nobili F, Mayer G, Leenders KL, Oertel WH; REMPET Study Group.

J Nucl Med. 2018 Sep;59(9):1437-1444. doi: 10.2967/jnumed.117.202242. Epub 2018 Feb 23.

9.

The Alzheimer's disease metabolic brain pattern in mild cognitive impairment.

Meles SK, Pagani M, Arnaldi D, De Carli F, Dessi B, Morbelli S, Sambuceti G, Jonsson C, Leenders KL, Nobili F.

J Cereb Blood Flow Metab. 2017 Dec;37(12):3643-3648. doi: 10.1177/0271678X17732508. Epub 2017 Sep 20.

10.

Clinical utility and research frontiers of neuroimaging in movement disorders.

Nobili F, Westman E, Kogan RV, Pereira JB, Massa F, Grazzini M, Meles SK, Leenders KL.

Q J Nucl Med Mol Imaging. 2017 Dec;61(4):372-385. doi: 10.23736/S1824-4785.17.03018-7. Epub 2017 Aug 28. Review.

11.

FDG PET, dopamine transporter SPECT, and olfaction: Combining biomarkers in REM sleep behavior disorder.

Meles SK, Vadasz D, Renken RJ, Sittig-Wiegand E, Mayer G, Depboylu C, Reetz K, Overeem S, Pijpers A, Reesink FE, van Laar T, Heinen L, Teune LK, Höffken H, Luster M, Kesper K, Adriaanse SM, Booij J, Leenders KL, Oertel WH.

Mov Disord. 2017 Oct;32(10):1482-1486. doi: 10.1002/mds.27094. Epub 2017 Jul 22.

12.

Dual time point method for the quantification of irreversible tracer kinetics: A reference tissue approach applied to [18F]-FDOPA brain PET.

Lopes Alves I, Meles SK, Willemsen AT, Dierckx RA, Marques da Silva AM, Leenders KL, Koole M.

J Cereb Blood Flow Metab. 2017 Sep;37(9):3124-3134. doi: 10.1177/0271678X16684137. Epub 2016 Dec 19.

13.

Metabolic Imaging in Parkinson Disease.

Meles SK, Teune LK, de Jong BM, Dierckx RA, Leenders KL.

J Nucl Med. 2017 Jan;58(1):23-28. doi: 10.2967/jnumed.116.183152. Epub 2016 Nov 22. Review.

14.

Hippocampus activation related to 'real-time' processing of visuospatial change.

Beudel M, Leenders KL, de Jong BM.

Brain Res. 2016 Dec 1;1652:204-211. doi: 10.1016/j.brainres.2016.10.010. Epub 2016 Oct 11.

PMID:
27742470
15.

Speech dysprosody but no music 'dysprosody' in Parkinson's disease.

Harris R, Leenders KL, de Jong BM.

Brain Lang. 2016 Dec;163:1-9. doi: 10.1016/j.bandl.2016.08.008. Epub 2016 Sep 12.

16.

How typical are 'typical' tremor characteristics? Sensitivity and specificity of five tremor phenomena.

van der Stouwe AM, Elting JW, van der Hoeven JH, van Laar T, Leenders KL, Maurits NM, Tijssen MA.

Parkinsonism Relat Disord. 2016 Sep;30:23-8. doi: 10.1016/j.parkreldis.2016.06.008. Epub 2016 Jun 16.

PMID:
27346607
17.

Relation of 18-F-Dopa PET with hypokinesia-rigidity, tremor and freezing in Parkinson's disease.

Pikstra ARA, van der Hoorn A, Leenders KL, de Jong BM.

Neuroimage Clin. 2016 Jan 12;11:68-72. doi: 10.1016/j.nicl.2016.01.010. eCollection 2016.

18.

Lateral and Medial Ventral Occipitotemporal Regions Interact During the Recognition of Images Revealed from Noise.

Nordhjem B, Ćurčić-Blake B, Meppelink AM, Renken RJ, de Jong BM, Leenders KL, van Laar T, Cornelissen FW.

Front Hum Neurosci. 2016 Jan 6;9:678. doi: 10.3389/fnhum.2015.00678. eCollection 2015.

19.

DNAJC6 Mutations Associated With Early-Onset Parkinson's Disease.

Olgiati S, Quadri M, Fang M, Rood JP, Saute JA, Chien HF, Bouwkamp CG, Graafland J, Minneboo M, Breedveld GJ, Zhang J; International Parkinsonism Genetics Network, Verheijen FW, Boon AJ, Kievit AJ, Jardim LB, Mandemakers W, Barbosa ER, Rieder CR, Leenders KL, Wang J, Bonifati V.

Ann Neurol. 2016 Feb;79(2):244-56. doi: 10.1002/ana.24553. Epub 2016 Jan 14.

PMID:
26528954
20.

Muscle co-activity tuning in Parkinsonian hand movement: disease-specific changes at behavioral and cerebral level.

van der Stouwe AM, Toxopeus CM, de Jong BM, Yavuz P, Valsan G, Conway BA, Leenders KL, Maurits NM.

Front Hum Neurosci. 2015 Aug 5;9:437. doi: 10.3389/fnhum.2015.00437. eCollection 2015.

21.

Abnormal metabolic pattern associated with cognitive impairment in Parkinson's disease: a validation study.

Meles SK, Tang CC, Teune LK, Dierckx RA, Dhawan V, Mattis PJ, Leenders KL, Eidelberg D.

J Cereb Blood Flow Metab. 2015 Sep;35(9):1478-84. doi: 10.1038/jcbfm.2015.112. Epub 2015 Jun 10.

22.

Classification of Parkinsonian syndromes from FDG-PET brain data using decision trees with SSM/PCA features.

Mudali D, Teune LK, Renken RJ, Leenders KL, Roerdink JB.

Comput Math Methods Med. 2015;2015:136921. doi: 10.1155/2015/136921. Epub 2015 Mar 31.

23.

Can repetitive transcranial magnetic stimulation increase muscle strength in functional neurological paresis? A proof-of-principle study.

Broersma M, Koops EA, Vroomen PC, Van der Hoeven JH, Aleman A, Leenders KL, Maurits NM, van Beilen M.

Eur J Neurol. 2015 May;22(5):866-73. doi: 10.1111/ene.12684. Epub 2015 Feb 24.

PMID:
25708187
24.

The Alzheimer's disease-related glucose metabolic brain pattern.

Teune LK, Strijkert F, Renken RJ, Izaks GJ, de Vries JJ, Segbers M, Roerdink JB, Dierckx RA, Leenders KL.

Curr Alzheimer Res. 2014;11(8):725-32.

PMID:
25212911
25.

A disease-specific metabolic brain network associated with corticobasal degeneration.

Niethammer M, Tang CC, Feigin A, Allen PJ, Heinen L, Hellwig S, Amtage F, Hanspal E, Vonsattel JP, Poston KL, Meyer PT, Leenders KL, Eidelberg D.

Brain. 2014 Nov;137(Pt 11):3036-46. doi: 10.1093/brain/awu256. Epub 2014 Sep 9.

26.

Parkinson's disease-related perfusion and glucose metabolic brain patterns identified with PCASL-MRI and FDG-PET imaging.

Teune LK, Renken RJ, de Jong BM, Willemsen AT, van Osch MJ, Roerdink JB, Dierckx RA, Leenders KL.

Neuroimage Clin. 2014 Jul 3;5:240-4. doi: 10.1016/j.nicl.2014.06.007. eCollection 2014.

27.

Standardized handwriting to assess bradykinesia, micrographia and tremor in Parkinson's disease.

Smits EJ, Tolonen AJ, Cluitmans L, van Gils M, Conway BA, Zietsma RC, Leenders KL, Maurits NM.

PLoS One. 2014 May 22;9(5):e97614. doi: 10.1371/journal.pone.0097614. eCollection 2014.

28.

Striatal metabolism and psychomotor speed as predictors of motor onset in Huntington's disease.

Herben-Dekker M, van Oostrom JC, Roos RA, Jurgens CK, Witjes-Ané MN, Kremer HP, Leenders KL, Spikman JM.

J Neurol. 2014 Jul;261(7):1387-97. doi: 10.1007/s00415-014-7350-7. Epub 2014 Apr 30.

PMID:
24781835
29.

Parkinson-related changes of activation in visuomotor brain regions during perceived forward self-motion.

van der Hoorn A, Renken RJ, Leenders KL, de Jong BM.

PLoS One. 2014 Apr 22;9(4):e95861. doi: 10.1371/journal.pone.0095861. eCollection 2014.

30.

Adenosine A(2A) receptor antagonists as Positron Emission Tomography (PET) tracers.

Khanapur S, Waarde Av, Ishiwata K, Leenders KL, Dierckx RA, Elsinga PH.

Curr Med Chem. 2014;21(3):312-28. Review.

PMID:
24059232
31.

Metabolic network as a progression biomarker of premanifest Huntington's disease.

Tang CC, Feigin A, Ma Y, Habeck C, Paulsen JS, Leenders KL, Teune LK, van Oostrom JC, Guttman M, Dhawan V, Eidelberg D.

J Clin Invest. 2013 Sep;123(9):4076-88. doi: 10.1172/JCI69411. Epub 2013 Aug 29.

32.

Acceleration bias in visually perceived velocity change and effects of Parkinson's bradykinesia.

Beudel M, de Geus CM, Leenders KL, de Jong BM.

Neuroreport. 2013 Oct 2;24(14):773-8. doi: 10.1097/WNR.0b013e328363f739.

PMID:
23979256
33.

Validation of parkinsonian disease-related metabolic brain patterns.

Teune LK, Renken RJ, Mudali D, De Jong BM, Dierckx RA, Roerdink JB, Leenders KL.

Mov Disord. 2013 Apr;28(4):547-51. doi: 10.1002/mds.25361. Epub 2013 Mar 11.

PMID:
23483593
34.

Motor behavior correlates with striatal [¹⁸F]-DOPA uptake in MPTP-lesioned primates.

Kortekaas R, Eshuis SA, Andringa G, Cools AR, Leenders KL.

Neurochem Int. 2013 Mar;62(4):349-53. doi: 10.1016/j.neuint.2013.01.021. Epub 2013 Jan 26.

PMID:
23357476
35.

Neuropsychological and emotional correlates of personality traits in Parkinson's disease.

Koerts J, Tucha L, Leenders KL, Tucha O.

Behav Neurol. 2013 Jan 1;27(4):567-74. doi: 10.3233/BEN-129017.

36.

Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in Parkinson patients.

Toxopeus CM, Maurits NM, Valsan G, Conway BA, Leenders KL, de Jong BM.

PLoS One. 2012;7(7):e41042. doi: 10.1371/journal.pone.0041042. Epub 2012 Jul 23.

37.

Successful surgical treatment of an arachnoid cyst inducing a Holmes' tremor.

Coumou AD, van Dijk JM, De Vries JJ, Leenders KL, Kuijlen JM.

Mov Disord. 2012 Jul;27(8):964. doi: 10.1002/mds.25039. No abstract available.

PMID:
22807187
38.

Reduced parietal activation in cervical dystonia after parietal TMS interleaved with fMRI.

de Vries PM, de Jong BM, Bohning DE, Hinson VK, George MS, Leenders KL.

Clin Neurol Neurosurg. 2012 Sep;114(7):914-21. doi: 10.1016/j.clineuro.2012.02.006. Epub 2012 Mar 2.

39.

Executive functioning in daily life in Parkinson's disease: initiative, planning and multi-task performance.

Koerts J, Van Beilen M, Tucha O, Leenders KL, Brouwer WH.

PLoS One. 2011;6(12):e29254. doi: 10.1371/journal.pone.0029254. Epub 2011 Dec 20.

40.

Narrowing wide-field optic flow affects treadmill gait in left-sided Parkinson's disease.

van der Hoorn A, Hof AL, Leenders KL, de Jong BM.

Mov Disord. 2012 Apr;27(4):580-1. doi: 10.1002/mds.24011. Epub 2011 Dec 15. No abstract available.

PMID:
22173937
41.

Sentence comprehension and its association with executive functions in patients with Parkinson's disease.

Colman KS, Koerts J, Stowe LA, Leenders KL, Bastiaanse R.

Parkinsons Dis. 2011;2011:213983. doi: 10.4061/2011/213983. Epub 2011 Oct 24.

42.

Direction of movement is encoded in the human primary motor cortex.

Toxopeus CM, de Jong BM, Valsan G, Conway BA, Leenders KL, Maurits NM.

PLoS One. 2011;6(11):e27838. doi: 10.1371/journal.pone.0027838. Epub 2011 Nov 16.

43.

Abnormal parietal function in conversion paresis.

van Beilen M, de Jong BM, Gieteling EW, Renken R, Leenders KL.

PLoS One. 2011;6(10):e25918. doi: 10.1371/journal.pone.0025918. Epub 2011 Oct 24.

44.

Complaints about impairments in executive functions in Parkinson's disease: the association with neuropsychological assessment.

Koerts J, van Beilen M, Leenders KL, Brouwer WH, Tucha L, Tucha O.

Parkinsonism Relat Disord. 2012 Feb;18(2):194-7. doi: 10.1016/j.parkreldis.2011.10.002. Epub 2011 Oct 17.

45.

Handedness correlates with the dominant Parkinson side: a systematic review and meta-analysis.

van der Hoorn A, Burger H, Leenders KL, de Jong BM.

Mov Disord. 2012 Feb;27(2):206-10. doi: 10.1002/mds.24007. Epub 2011 Oct 12. Review.

PMID:
21994149
46.

Breakpoint mapping of 13 large parkin deletions/duplications reveals an exon 4 deletion and an exon 7 duplication as founder mutations.

Elfferich P, Verleun-Mooijman MC, Maat-Kievit JA, van de Warrenburg BP, Abdo WF, Eshuis SA, Leenders KL, Hovestadt A, Zijlmans JC, Stroy JP, van Swieten JC, Boon AJ, van Engelen K, Verschuuren-Bemelmans CC, Lesnik-Oberstein SA, Tassorelli C, Lopiano L, Bonifati V, Dooijes D, van Minkelen R.

Neurogenetics. 2011 Nov;12(4):263-71. doi: 10.1007/s10048-011-0302-9. Epub 2011 Oct 13.

47.

Impairment of gradual muscle adjustment during wrist circumduction in Parkinson's disease.

Toxopeus CM, de Jong BM, Valsan G, Conway BA, van der Hoeven JH, Leenders KL, Maurits NM.

PLoS One. 2011;6(9):e24572. doi: 10.1371/journal.pone.0024572. Epub 2011 Sep 2.

48.

Subjective and objective assessment of executive functions in Parkinson's disease.

Koerts J, Tucha L, Leenders KL, van Beilen M, Brouwer WH, Tucha O.

J Neurol Sci. 2011 Nov 15;310(1-2):172-5. doi: 10.1016/j.jns.2011.07.009. Epub 2011 Jul 31.

49.

Handedness and dominant side of symptoms in Parkinson's disease.

van der Hoorn A, Bartels AL, Leenders KL, de Jong BM.

Parkinsonism Relat Disord. 2011 Jan;17(1):58-60. doi: 10.1016/j.parkreldis.2010.10.002. Epub 2010 Oct 25.

PMID:
20974546
50.

Transcutaneous port for continuous duodenal levodopa/carbidopa administration in Parkinson's disease.

Meppelink AM, Nyman R, van Laar T, Drent M, Prins T, Leenders KL.

Mov Disord. 2011 Feb 1;26(2):331-4. doi: 10.1002/mds.23408. Epub 2010 Oct 19.

PMID:
20960486

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