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Items: 1 to 50 of 80

1.

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.

Scantlebery AML, Uil M, Butter LM, Poelman R, Claessen N, Girardin SE, Florquin S, Roelofs JJTH, Leemans JC.

PLoS One. 2019 Mar 25;14(3):e0214437. doi: 10.1371/journal.pone.0214437. eCollection 2019.

2.

Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain.

Uil M, Scantlebery AML, Butter LM, Larsen PWB, de Boer OJ, Leemans JC, Florquin S, Roelofs JJTH.

Sci Rep. 2019 Feb 27;9(1):3425. doi: 10.1038/s41598-018-38075-4.

3.

Mitochondrial DNA: Innocent in Plasma, but Guilty in Urine?

Jansen MPB, Roelofs JJTH, Leemans JC.

Shock. 2019 Feb;51(2):267. doi: 10.1097/SHK.0000000000001143. No abstract available.

PMID:
30645207
4.

Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection.

Emal D, Rampanelli E, Claessen N, Bemelman FJ, Leemans JC, Florquin S, Dessing MC.

Sci Rep. 2019 Jan 14;9(1):106. doi: 10.1038/s41598-018-37482-x.

5.

Urinary mitochondrial deoxyribonucleic acid associates with delayed graft function following renal transplantation.

Jansen MPB, Pulskens WPC, Uil M, Claessen N, Nieuwenhuizen G, Standaar D, Hau CM, Nieuwland R, Florquin S, Bemelman FJ, Leemans JC, Roelofs JJTH.

Nephrol Dial Transplant. 2018 Dec 24. doi: 10.1093/ndt/gfy372. [Epub ahead of print]

PMID:
30590723
6.

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney.

Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC.

J Pathol. 2018 Dec;246(4):470-484. doi: 10.1002/path.5150. Epub 2018 Nov 5.

PMID:
30073645
7.

S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy.

Tammaro A, Florquin S, Brok M, Claessen N, Butter LM, Teske GJD, de Boer OJ, Vogl T, Leemans JC, Dessing MC.

Clin Exp Immunol. 2018 Sep;193(3):361-375. doi: 10.1111/cei.13154.

8.

Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain.

Uil M, Scantlebery AML, Butter LM, Larsen PWB, de Boer OJ, Leemans JC, Florquin S, Roelofs JJTH.

Sci Rep. 2018 Apr 3;8(1):5542. doi: 10.1038/s41598-018-23839-9. Erratum in: Sci Rep. 2019 Feb 27;9(1):3425.

9.

No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction.

Stroo I, Emal D, Butter LM, Teske GJ, Claessen N, Dessing MC, Girardin SE, Florquin S, Leemans JC.

BMC Nephrol. 2018 Apr 2;19(1):78. doi: 10.1186/s12882-018-0867-8.

10.

Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome.

Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC.

Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1883-1895. doi: 10.1016/j.bbadis.2018.03.003. Epub 2018 Mar 4.

11.

Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction.

Jansen MPB, Pulskens WP, Butter LM, Florquin S, Juffermans NP, Roelofs JJTH, Leemans JC.

Shock. 2018 Mar;49(3):301-310. doi: 10.1097/SHK.0000000000000967.

PMID:
28837526
12.

High glucose induces HGF-independent activation of Met receptor in human renal tubular epithelium.

Mesarosova L, Ochodnicky P, Leemans JC, Florquin S, Krenek P, Klimas J.

J Recept Signal Transduct Res. 2017 Dec;37(6):535-542. doi: 10.1080/10799893.2017.1365902. Epub 2017 Aug 18.

PMID:
28819999
13.

Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy.

Ochodnicky P, Lattenist L, Ahdi M, Kers J, Uil M, Claessen N, Leemans JC, Florquin S, Meijers JCM, Gerdes VEA, Roelofs JJTH.

Am J Pathol. 2017 Sep;187(9):1971-1983. doi: 10.1016/j.ajpath.2017.05.004. Epub 2017 Jun 29.

PMID:
28668213
14.

NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity.

Stokman G, Kors L, Bakker PJ, Rampanelli E, Claessen N, Teske GJD, Butter L, van Andel H, van den Bergh Weerman MA, Larsen PWB, Dessing MC, Zuurbier CJ, Girardin SE, Florquin S, Leemans JC.

J Exp Med. 2017 Aug 7;214(8):2405-2420. doi: 10.1084/jem.20161031. Epub 2017 Jun 16.

15.

Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation.

Rampanelli E, Orsó E, Ochodnicky P, Liebisch G, Bakker PJ, Claessen N, Butter LM, van den Bergh Weerman MA, Florquin S, Schmitz G, Leemans JC.

Sci Rep. 2017 Jun 6;7(1):2861. doi: 10.1038/s41598-017-01994-9.

16.

Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation.

Tammaro A, Kers J, Emal D, Stroo I, Teske GJ, Butter LM, Claessen N, Damman J, Derive M, Navis GJ, Florquin S, Leemans JC, Dessing MC.

Sci Rep. 2017 Mar 15;7:44163. doi: 10.1038/srep44163. No abstract available.

17.

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives.

Tammaro A, Derive M, Gibot S, Leemans JC, Florquin S, Dessing MC.

Pharmacol Ther. 2017 Sep;177:81-95. doi: 10.1016/j.pharmthera.2017.02.043. Epub 2017 Feb 27. Review.

18.

Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation.

Tammaro A, Kers J, Emal D, Stroo I, Teske GJD, Butter LM, Claessen N, Damman J, Derive M, Navis GJ, Florquin S, Leemans JC, Dessing MC.

Sci Rep. 2016 Dec 8;6:38275. doi: 10.1038/srep38275. Erratum in: Sci Rep. 2017 Mar 15;7:44163.

19.

Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury.

Emal D, Rampanelli E, Stroo I, Butter LM, Teske GJ, Claessen N, Stokman G, Florquin S, Leemans JC, Dessing MC.

J Am Soc Nephrol. 2017 May;28(5):1450-1461. doi: 10.1681/ASN.2016030255. Epub 2016 Dec 7.

20.

Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation.

Dessing MC, Kers J, Damman J, Navis GJ, Florquin S, Leemans JC.

Sci Rep. 2016 Nov 7;6:36315. doi: 10.1038/srep36315.

21.

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.

Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, Confalonieri S, Bertalot G, Pece S, Settembre C, Malouf GG, Leemans JC, de Heer E, Salvatore M, Peters DJ, Di Fiore PP, Ballabio A.

Elife. 2016 Sep 26;5. pii: e17047. doi: 10.7554/eLife.17047.

22.

An Overview of Pathways of Regulated Necrosis in Acute Kidney Injury.

Kers J, Leemans JC, Linkermann A.

Semin Nephrol. 2016 May;36(3):139-52. doi: 10.1016/j.semnephrol.2016.03.002. Review.

PMID:
27339380
23.

Renal endothelial protein C receptor expression and shedding during diabetic nephropathy.

Lattenist L, Ochodnický P, Ahdi M, Claessen N, Leemans JC, Satchell SC, Florquin S, Gerdes VE, Roelofs JJ.

J Thromb Haemost. 2016 Jun;14(6):1171-82. doi: 10.1111/jth.13315. Epub 2016 May 6.

24.

Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation.

Dessing MC, Kers J, Damman J, Leuvenink HG, van Goor H, Hillebrands JL, Hepkema BG, Snieder H, van den Born J, de Borst MH, Bakker SJ, Navis GJ, Ploeg RJ, Florquin S, Seelen M, Leemans JC.

PLoS One. 2015 Oct 7;10(10):e0139769. doi: 10.1371/journal.pone.0139769. eCollection 2015.

25.

TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion.

Bakker PJ, Scantlebery AM, Butter LM, Claessen N, Teske GJ, van der Poll T, Florquin S, Leemans JC.

PLoS One. 2015 Sep 11;10(9):e0137511. doi: 10.1371/journal.pone.0137511. eCollection 2015.

26.

Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury.

Stroo I, Claessen N, Teske GJ, Butter LM, Florquin S, Leemans JC.

PLoS One. 2015 Apr 13;10(4):e0123203. doi: 10.1371/journal.pone.0123203. eCollection 2015.

27.

Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression.

Jong WM, Leemans JC, Weber NC, Juffermans NP, Schultz MJ, Hollmann MW, Zuurbier CJ.

Int J Cardiol. 2014 Nov 15;177(1):41-3. doi: 10.1016/j.ijcard.2014.09.148. Epub 2014 Oct 10. No abstract available.

PMID:
25499334
28.

The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion.

Dessing MC, Tammaro A, Pulskens WP, Teske GJ, Butter LM, Claessen N, van Eijk M, van der Poll T, Vogl T, Roth J, Florquin S, Leemans JC.

Kidney Int. 2015 Jan;87(1):85-94. doi: 10.1038/ki.2014.216. Epub 2014 Jun 18.

29.

Pattern recognition receptors and the inflammasome in kidney disease.

Leemans JC, Kors L, Anders HJ, Florquin S.

Nat Rev Nephrol. 2014 Jul;10(7):398-414. doi: 10.1038/nrneph.2014.91. Epub 2014 Jun 3. Review.

PMID:
24890433
30.

A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion.

Bakker PJ, Butter LM, Claessen N, Teske GJ, Sutterwala FS, Florquin S, Leemans JC.

Am J Pathol. 2014 Jul;184(7):2013-22. doi: 10.1016/j.ajpath.2014.04.005. Epub 2014 May 11.

31.

Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy.

Rampanelli E, Rouschop KM, Claessen N, Teske GJ, Pals ST, Leemans JC, Florquin S.

Kidney Int. 2014 Sep;86(3):558-69. doi: 10.1038/ki.2014.87. Epub 2014 Apr 9.

32.

Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.

Pulskens WP, Butter LM, Teske GJ, Claessen N, Dessing MC, Flavell RA, Sutterwala FS, Florquin S, Leemans JC.

PLoS One. 2014 Jan 15;9(1):e85775. doi: 10.1371/journal.pone.0085775. eCollection 2014.

33.

CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction.

Rampanelli E, Dessing MC, Claessen N, Teske GJ, Joosten SP, Pals ST, Leemans JC, Florquin S.

PLoS One. 2013 Dec 23;8(12):e84479. doi: 10.1371/journal.pone.0084479. eCollection 2013.

34.

Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy.

Tammaro A, Stroo I, Rampanelli E, Blank F, Butter LM, Claessen N, Takai T, Colonna M, Leemans JC, Florquin S, Dessing MC.

PLoS One. 2013 Dec 16;8(12):e82498. doi: 10.1371/journal.pone.0082498. eCollection 2013.

35.

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation.

Bakker PJ, Butter LM, Kors L, Teske GJ, Aten J, Sutterwala FS, Florquin S, Leemans JC.

Kidney Int. 2014 May;85(5):1112-22. doi: 10.1038/ki.2013.503. Epub 2013 Dec 18.

36.

CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.

Duitman J, Borensztajn KS, Pulskens WP, Leemans JC, Florquin S, Spek CA.

Lab Invest. 2014 Jan;94(1):89-97. doi: 10.1038/labinvest.2013.127. Epub 2013 Nov 18.

37.

CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy.

Rampanelli E, Rouschop K, Teske GJ, Claessen N, Leemans JC, Florquin S.

Am J Physiol Renal Physiol. 2013 Nov 15;305(10):F1445-54. doi: 10.1152/ajprenal.00340.2013. Epub 2013 Sep 11.

38.

Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis.

Geldhoff M, Mook-Kanamori BB, Brouwer MC, Troost D, Leemans JC, Flavell RA, Van der Ende A, Van der Poll T, Van de Beek D.

BMC Infect Dis. 2013 Jul 31;13:358. doi: 10.1186/1471-2334-13-358.

39.

CCAAT/enhancer-binding protein delta (C/EBPδ) plays a minor role in renal host defense against uropathogenic Escherichia coli.

Duitman J, Teske GJ, Butter LM, Leemans JC, Florquin S, Spek CA.

Transpl Infect Dis. 2013 Jun;15(3):E119-21. doi: 10.1111/tid.12081. Epub 2013 Apr 14. No abstract available.

PMID:
23582055
40.

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease.

Stroo I, Butter LM, Claessen N, Teske GJ, Rubino SJ, Girardin SE, Florquin S, Leemans JC.

Biol Open. 2012 Dec 15;1(12):1239-47. doi: 10.1242/bio.2012554. Epub 2012 Oct 11.

41.

The toll interleukin-1 receptor (IL-1R) 8/single Ig domain IL-1R-related molecule modulates the renal response to bacterial infection.

Leemans JC, Butter LM, Teske GJ, Stroo I, Pulskens WP, Florquin S.

Infect Immun. 2012 Nov;80(11):3812-20. doi: 10.1128/IAI.00422-12. Epub 2012 Aug 13.

42.

Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling.

Zuurbier CJ, Jong WM, Eerbeek O, Koeman A, Pulskens WP, Butter LM, Leemans JC, Hollmann MW.

PLoS One. 2012;7(7):e40643. doi: 10.1371/journal.pone.0040643. Epub 2012 Jul 27.

43.

Beneficial effects of gaseous hydrogen sulfide in hepatic ischemia/reperfusion injury.

Bos EM, Snijder PM, Jekel H, Weij M, Leemans JC, van Dijk MC, Hillebrands JL, Lisman T, van Goor H, Leuvenink HG.

Transpl Int. 2012 Aug;25(8):897-908. doi: 10.1111/j.1432-2277.2012.01514.x. Epub 2012 Jun 21.

44.

Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.

Kuipers MT, Aslami H, Janczy JR, van der Sluijs KF, Vlaar AP, Wolthuis EK, Choi G, Roelofs JJ, Flavell RA, Sutterwala FS, Bresser P, Leemans JC, van der Poll T, Schultz MJ, Wieland CW.

Anesthesiology. 2012 May;116(5):1104-15. doi: 10.1097/ALN.0b013e3182518bc0.

PMID:
22531249
45.

RAGE does not contribute to renal injury and damage upon ischemia/reperfusion-induced injury.

Dessing MC, Pulskens WP, Teske GJ, Butter LM, van der Poll T, Yang H, Tracey KJ, Nawroth PP, Bierhaus A, Florquin S, Leemans JC.

J Innate Immun. 2012;4(1):80-5. doi: 10.1159/000334251. Epub 2011 Nov 4.

46.

Sensing damage by the NLRP3 inflammasome.

Leemans JC, Cassel SL, Sutterwala FS.

Immunol Rev. 2011 Sep;243(1):152-62. doi: 10.1111/j.1600-065X.2011.01043.x. Review.

47.

Stem cell factor expression after renal ischemia promotes tubular epithelial survival.

Stokman G, Stroo I, Claessen N, Teske GJ, Weening JJ, Leemans JC, Florquin S.

PLoS One. 2010 Dec 21;5(12):e14386. doi: 10.1371/journal.pone.0014386.

48.

S100A8/A9 is not involved in host defense against murine urinary tract infection.

Dessing MC, Butter LM, Teske GJ, Claessen N, van der Loos CM, Vogl T, Roth J, van der Poll T, Florquin S, Leemans JC.

PLoS One. 2010 Oct 14;5(10):e13394. doi: 10.1371/journal.pone.0013394.

49.

Intragraft Toll-like receptor profiling in acute renal allograft rejection.

Dessing MC, Bemelman FJ, Claessen N, Ten Berge IJ, Florquin S, Leemans JC.

Nephrol Dial Transplant. 2010 Dec;25(12):4087-92. doi: 10.1093/ndt/gfq589. Epub 2010 Sep 27.

PMID:
20876367
50.

TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury.

Pulskens WP, Rampanelli E, Teske GJ, Butter LM, Claessen N, Luirink IK, van der Poll T, Florquin S, Leemans JC.

J Am Soc Nephrol. 2010 Aug;21(8):1299-308. doi: 10.1681/ASN.2009070722. Epub 2010 Jul 1.

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