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Items: 14

1.

Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease.

Bell SM, Barnes K, Clemmens H, Al-Rafiah AR, Al-Ofi EA, Leech V, Bandmann O, Shaw PJ, Blackburn DJ, Ferraiuolo L, Mortiboys H.

J Mol Biol. 2018 Oct 19;430(21):3942-3953. doi: 10.1016/j.jmb.2018.08.019. Epub 2018 Aug 29.

2.

Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length.

Callejas S, Leech V, Reitter C, Melville S.

Genome Res. 2006 Sep;16(9):1109-18. Epub 2006 Aug 9.

3.

The genome of the African trypanosome Trypanosoma brucei.

Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Böhme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertczak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM.

Science. 2005 Jul 15;309(5733):416-22.

4.

Separation, digestion, and cloning of intact parasite chromosomes embedded in agarose.

Leech V, Quail MA, Melville SE.

Methods Mol Biol. 2004;270:335-52.

PMID:
15153638
5.

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism.

Hall N, Berriman M, Lennard NJ, Harris BR, Hertz-Fowler C, Bart-Delabesse EN, Gerrard CS, Atkin RJ, Barron AJ, Bowman S, Bray-Allen SP, Bringaud F, Clark LN, Corton CH, Cronin A, Davies R, Doggett J, Fraser A, Grüter E, Hall S, Harper AD, Kay MP, Leech V, Mayes R, Price C, Quail MA, Rabbinowitsch E, Reitter C, Rutherford K, Sasse J, Sharp S, Shownkeen R, MacLeod A, Taylor S, Tweedie A, Turner CM, Tait A, Gull K, Barrell B, Melville SE.

Nucleic Acids Res. 2003 Aug 15;31(16):4864-73.

6.

The sequence and analysis of Trypanosoma brucei chromosome II.

El-Sayed NM, Ghedin E, Song J, MacLeod A, Bringaud F, Larkin C, Wanless D, Peterson J, Hou L, Taylor S, Tweedie A, Biteau N, Khalak HG, Lin X, Mason T, Hannick L, Caler E, Blandin G, Bartholomeu D, Simpson AJ, Kaul S, Zhao H, Pai G, Van Aken S, Utterback T, Haas B, Koo HL, Umayam L, Suh B, Gerrard C, Leech V, Qi R, Zhou S, Schwartz D, Feldblyum T, Salzberg S, Tait A, Turner CM, Ullu E, White O, Melville S, Adams MD, Fraser CM, Donelson JE.

Nucleic Acids Res. 2003 Aug 15;31(16):4856-63.

7.

A new, expressed multigene family containing a hot spot for insertion of retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei.

Bringaud F, Biteau N, Melville SE, Hez S, El-Sayed NM, Leech V, Berriman M, Hall N, Donelson JE, Baltz T.

Eukaryot Cell. 2002 Feb;1(1):137-51. Erratum in: Eukaryot Cell 2002 Apr;1(2):305.

8.
9.

The molecular karyotype of the megabase chromosomes of Trypanosoma brucei stock 427.

Melville SE, Leech V, Navarro M, Cross GA.

Mol Biochem Parasitol. 2000 Dec;111(2):261-73.

PMID:
11163435
10.

Analysis of ploidy (in megabase chromosomes) in Trypanosoma brucei after genetic exchange.

Hope M, MacLeod A, Leech V, Melville S, Sasse J, Tait A, Turner CM.

Mol Biochem Parasitol. 1999 Oct 25;104(1):1-9.

PMID:
10589977
11.

The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers.

Melville SE, Leech V, Gerrard CS, Tait A, Blackwell JM.

Mol Biochem Parasitol. 1998 Aug 1;94(2):155-73.

PMID:
9747967
12.

Polymerase chain reaction allelotyping of human ovarian cancer.

Osborne RJ, Leech V.

Br J Cancer. 1994 Mar;69(3):429-38.

13.

A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus.

Jacobs IJ, Smith SA, Wiseman RW, Futreal PA, Harrington T, Osborne RJ, Leech V, Molyneux A, Berchuck A, Ponder BA, et al.

Cancer Res. 1993 Mar 15;53(6):1218-21.

14.

T cell receptor gamma/delta expression on lymphocyte populations of breast cancer patients.

Alam SM, Clark JS, Leech V, Whitford P, George WD, Campbell AM.

Immunol Lett. 1992 Feb 15;31(3):279-83.

PMID:
1347754

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