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Items: 1 to 50 of 160

1.

Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.

Leech JM, Dhariwala MO, Lowe MM, Chu K, Merana GR, Cornuot C, Weckel A, Ma JM, Leitner EG, Gonzalez JR, Vasquez KS, Diep BA, Scharschmidt TC.

Cell Host Microbe. 2019 Dec 11;26(6):795-809.e5. doi: 10.1016/j.chom.2019.10.007. Epub 2019 Nov 26.

PMID:
31784259
2.

Comparative effectiveness and safety of pharmacological and non-pharmacological interventions for insomnia: an overview of reviews.

Rios P, Cardoso R, Morra D, Nincic V, Goodarzi Z, Farah B, Harricharan S, Morin CM, Leech J, Straus SE, Tricco AC.

Syst Rev. 2019 Nov 15;8(1):281. doi: 10.1186/s13643-019-1163-9.

3.

The C-Band All-Sky Survey (C-BASS): Simulated parametric fitting in single pixels in total intensity and polarization.

Jew L, Taylor AC, Jones ME, Barr A, Chiang HC, Dickinson C, Grumitt RDP, Harper SE, Heilgendorff HM, Hill-Valler J, Jonas JL, Leahy JP, Leech J, Pearson TJ, Peel MW, Readhead ACS, Sievers J.

Mon Not R Astron Soc. 2019 Dec;490(2):2958-2975. doi: 10.1093/mnras/stz2697. Epub 2019 Oct 7.

PMID:
31708598
4.

Regional brain stem activations during capsaicin inhalation using functional magnetic resonance imaging in humans.

Bautista TG, Leech J, Mazzone SB, Farrell MJ.

J Neurophysiol. 2019 Apr 1;121(4):1171-1182. doi: 10.1152/jn.00547.2018. Epub 2019 Jan 16.

PMID:
30649977
5.

Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization.

Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W.

Microbiome. 2018 Sep 5;6(1):154. doi: 10.1186/s40168-018-0533-1.

6.

ATP12A promotes mucus dysfunction during Type 2 airway inflammation.

Lennox AT, Coburn SL, Leech JA, Heidrich EM, Kleyman TR, Wenzel SE, Pilewski JM, Corcoran TE, Myerburg MM.

Sci Rep. 2018 Feb 1;8(1):2109. doi: 10.1038/s41598-018-20444-8.

7.

Is there a link between aging and microbiome diversity in exceptional mammalian longevity?

Hughes GM, Leech J, Puechmaille SJ, Lopez JV, Teeling EC.

PeerJ. 2018 Jan 8;6:e4174. doi: 10.7717/peerj.4174. eCollection 2018.

8.

The Staphylococcus aureus Cell Wall-Anchored Protein Clumping Factor A Is an Important T Cell Antigen.

Lacey KA, Leech JM, Lalor SJ, McCormack N, Geoghegan JA, McLoughlin RM.

Infect Immun. 2017 Nov 17;85(12). pii: e00549-17. doi: 10.1128/IAI.00549-17. Print 2017 Dec.

9.

IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections.

Leech JM, Lacey KA, Mulcahy ME, Medina E, McLoughlin RM.

J Immunol. 2017 Mar 15;198(6):2352-2365. doi: 10.4049/jimmunol.1601018. Epub 2017 Feb 6.

10.

Changes in sleep duration and recreational screen time among Canadians, 1998-2010.

Leech JA.

J Sleep Res. 2017 Apr;26(2):202-209. doi: 10.1111/jsr.12479. Epub 2016 Dec 20.

11.

Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa.

Mulcahy ME, Leech JM, Renauld JC, Mills KH, McLoughlin RM.

Mucosal Immunol. 2016 Nov;9(6):1429-1441. doi: 10.1038/mi.2016.24. Epub 2016 Mar 23.

PMID:
27007677
12.

A randomized, double-blind, placebo controlled, parallel group, efficacy study of alpha BRAIN® administered orally.

Solomon TM, Leech J, deBros GB, Murphy CA, Budson AE, Vassey EA, Solomon PR.

Hum Psychopharmacol. 2016 Mar;31(2):135-43. doi: 10.1002/hup.2520. Epub 2016 Feb 15.

PMID:
26876224
13.

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.

Brown AF, Murphy AG, Lalor SJ, Leech JM, O'Keeffe KM, Mac Aogáin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM.

PLoS Pathog. 2015 Nov 5;11(11):e1005226. doi: 10.1371/journal.ppat.1005226. eCollection 2015.

14.

Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection.

O'Keeffe KM, Wilk MM, Leech JM, Murphy AG, Laabei M, Monk IR, Massey RC, Lindsay JA, Foster TJ, Geoghegan JA, McLoughlin RM.

Infect Immun. 2015 Sep;83(9):3445-57. doi: 10.1128/IAI.00358-15. Epub 2015 Jun 22.

15.

A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas.

Leech JD, Lammers SH, Goldman S, Auricchio N, Bronson RT, Kwiatkowski DJ, Sahin M.

Mol Cancer Res. 2015 Mar;13(3):548-55. doi: 10.1158/1541-7786.MCR-14-0178. Epub 2014 Dec 29.

16.

Effects of short-term continuous positive airway pressure on myocardial sympathetic nerve function and energetics in patients with heart failure and obstructive sleep apnea: a randomized study.

Hall AB, Ziadi MC, Leech JA, Chen SY, Burwash IG, Renaud J, deKemp RA, Haddad H, Mielniczuk LM, Yoshinaga K, Guo A, Chen L, Walter O, Garrard L, DaSilva JN, Floras JS, Beanlands RS.

Circulation. 2014 Sep 9;130(11):892-901. doi: 10.1161/CIRCULATIONAHA.113.005893. Epub 2014 Jul 3.

PMID:
24993098
17.

Monitoring the efficacy of dendritic cell vaccination by early detection of (99m) Tc-HMPAO-labelled CD4(+) T cells.

Sharif-Paghaleh E, Leech J, Sunassee K, Ali N, Sagoo P, Lechler RI, Smyth LA, Lombardi G, Mullen GE.

Eur J Immunol. 2014 Jul;44(7):2188-91. doi: 10.1002/eji.201344337. Epub 2014 Apr 14.

18.

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.

Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M.

Hum Mol Genet. 2014 Jul 15;23(14):3865-74. doi: 10.1093/hmg/ddu101. Epub 2014 Mar 5.

19.

Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis.

Kong SW, Sahin M, Collins CD, Wertz MH, Campbell MG, Leech JD, Krueger D, Bear MF, Kunkel LM, Kohane IS.

Mol Autism. 2014 Feb 24;5(1):16. doi: 10.1186/2040-2392-5-16.

20.

Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design.

Brown AF, Leech JM, Rogers TR, McLoughlin RM.

Front Immunol. 2014 Jan 8;4:507. doi: 10.3389/fimmu.2013.00507. Review.

21.

Brain activity associated with placebo suppression of the urge-to-cough in humans.

Leech J, Mazzone SB, Farrell MJ.

Am J Respir Crit Care Med. 2013 Nov 1;188(9):1069-75. doi: 10.1164/rccm.201306-1079OC.

PMID:
24093551
22.

Continuous-combined oral estradiol/drospirenone has no detrimental effect on cognitive performance and improves estrogen deficiency symptoms in early postmenopausal women: a randomized placebo-controlled trial.

Davison SL, Bell RJ, Robinson PJ, Jane F, Leech J, Maruff P, Egan GF, Davis SR.

Menopause. 2013 Oct;20(10):1020-6. doi: 10.1097/GME.0b013e318287474f.

PMID:
23591255
23.

Whole-body imaging of adoptively transferred T cells using magnetic resonance imaging, single photon emission computed tomography and positron emission tomography techniques, with a focus on regulatory T cells.

Leech JM, Sharif-Paghaleh E, Maher J, Livieratos L, Lechler RI, Mullen GE, Lombardi G, Smyth LA.

Clin Exp Immunol. 2013 May;172(2):169-77. doi: 10.1111/cei.12087.

24.

Promoting transplantation tolerance; adoptive regulatory T cell therapy.

Safinia N, Leech J, Hernandez-Fuentes M, Lechler R, Lombardi G.

Clin Exp Immunol. 2013 May;172(2):158-68. doi: 10.1111/cei.12052. Review.

25.

Sensorimotor circuitry involved in the higher brain control of coughing.

Mazzone SB, McGovern AE, Yang SK, Woo A, Phipps S, Ando A, Leech J, Farrell MJ.

Cough. 2013 Mar 6;9(1):7. doi: 10.1186/1745-9974-9-7.

26.

The association between personal care products and lung function.

Dales RE, Cakmak S, Leech J, Liu L.

Ann Epidemiol. 2013 Feb;23(2):49-53. doi: 10.1016/j.annepidem.2012.11.006.

PMID:
23305691
27.

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.

Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M.

Nature. 2012 Aug 30;488(7413):647-51. doi: 10.1038/nature11310.

28.

The effect of placebo conditioning on capsaicin-evoked urge to cough.

Leech J, Mazzone SB, Farrell MJ.

Chest. 2012 Oct;142(4):951-957. doi: 10.1378/chest.12-0362.

PMID:
22661453
29.

The influence of air pollution on cardiovascular and pulmonary function and exercise capacity: Canadian Health Measures Survey (CHMS).

Cakmak S, Dales R, Leech J, Liu L.

Environ Res. 2011 Nov;111(8):1309-12. doi: 10.1016/j.envres.2011.09.016. Epub 2011 Oct 13.

PMID:
22000598
30.

Population health delivers.

Leech JD.

Trustee. 2011 Jul-Aug;64(7):28-9, 1.

PMID:
21870698
31.

Novel use of the gelport to expedite transition to robot-assisted partial nephrectomy.

Kalra P, Leech JE, Tirado SM, Moreno JG.

J Endourol. 2010 Jun;24(6):947-8. doi: 10.1089/end.2009.0561.

PMID:
20345273
32.

Voluntary increase in latissimus dorsi muscle activity during the lat pull-down following expert instruction.

Snyder BJ, Leech JR.

J Strength Cond Res. 2009 Nov;23(8):2204-9. doi: 10.1519/JSC.0b013e3181bb7213.

PMID:
19826307
33.

Air pollution and emergency department visits for cardiac and respiratory conditions: a multi-city time-series analysis.

Stieb DM, Szyszkowicz M, Rowe BH, Leech JA.

Environ Health. 2009 Jun 10;8:25. doi: 10.1186/1476-069X-8-25.

34.
35.
36.

Crisis in the workplace.

Koerner J, King OW 3rd, Leech J.

Trustee. 2007 Apr;60(4):24-6, 28, 1.

PMID:
17491190
37.

The effects of continuous positive airway pressure on myocardial energetics in patients with heart failure and obstructive sleep apnea.

Yoshinaga K, Burwash IG, Leech JA, Haddad H, Johnson CB, deKemp RA, Garrard L, Chen L, Williams K, DaSilva JN, Beanlands RS.

J Am Coll Cardiol. 2007 Jan 30;49(4):450-8.

38.

Exposure time and place: do COPD patients differ from the general population?

Leech JA, Smith-Doiron M.

J Expo Sci Environ Epidemiol. 2006 May;16(3):238-41.

PMID:
16205788
39.

Frequency of emergency room visits for childhood asthma in Ottawa, Canada: the role of weather.

Villeneuve PJ, Leech J, Bourque D.

Int J Biometeorol. 2005 Sep;50(1):48-56. Epub 2005 Apr 22.

PMID:
15846521
40.

[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].

Kałuzny JJ, Szaflik J, Czechowicz-Janicka K, Kałuzny J, Orzałkiewicz A, Zaleska-Zmijewska A, Krajewska M, Stewart JA, Leech JN, Stewart WC.

Klin Oczna. 2004;106(1-2 Suppl):241-2. Polish.

PMID:
15510513
41.

Health in occupants of energy efficient new homes.

Leech JA, Raizenne M, Gusdorf J.

Indoor Air. 2004 Jun;14(3):169-73.

PMID:
15104783
42.

Survey reveals human rights abuses in Alberta.

Leech J.

Can HIV AIDS Policy Law Rev. 2003 Apr;8(1):24.

PMID:
12924292
43.

Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.

Kałuzny JJ, Szaflik J, Czechowicz-Janicka K, Kałuzny J, Orzalkiewicz A, Zaleska A, Krajewska M, Stewart JA, Leech JN, Stewart WC.

Acta Ophthalmol Scand. 2003 Aug;81(4):349-54.

44.

Acute and chronic ocular symptoms of dorzolamide 2% compared with placebo.

Stewart WC, Stewart JA, Leech JN.

J Glaucoma. 2003 Apr;12(2):151-5.

PMID:
12671470
45.

Conjunctival hyperemia in healthy subjects after short-term dosing with latanoprost, bimatoprost, and travoprost.

Stewart WC, Kolker AE, Stewart JA, Leech J, Jackson AL.

Am J Ophthalmol. 2003 Mar;135(3):314-20.

PMID:
12614748
46.

The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma.

Konstas AG, Kozobolis VP, Tersis I, Leech J, Stewart WC.

Eye (Lond). 2003 Jan;17(1):41-6.

PMID:
12579169
47.
48.

It's about time: a comparison of Canadian and American time-activity patterns.

Leech JA, Nelson WC, Burnett RT, Aaron S, Raizenne ME.

J Expo Anal Environ Epidemiol. 2002 Nov;12(6):427-32.

49.
50.

Hospital closure: reasons for concern.

Leech JD.

Trustee. 2002 Jul-Aug;55(7):28. No abstract available.

PMID:
12141061

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