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C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.

Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL 3rd, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, Gearing M, Ghetti B, Van Deerlin VM, Lee VM, Trojanowski JQ, Mok KY, Ling H, Dickson DW, Schellenberg GD, Ling SC, Lee EB.

Acta Neuropathol. 2019 Jul 20. doi: 10.1007/s00401-019-02045-5. [Epub ahead of print]


Sequence and Observer Variability in Gadoxectic Acid-Enhanced MRI Lesion Measurements in Hepatocellular Carcinoma.

van Lunenburg JTJ, Tripathi V, Chan VSH, Lee VKH, Lee EY, Vardhanabhuti V, Chiu KWH.

Acad Radiol. 2019 Jul 17. pii: S1076-6332(19)30318-6. doi: 10.1016/j.acra.2019.05.021. [Epub ahead of print]


Comparing antral follicle count and serum anti-Mullerian hormone level for determination of gonadotrophin dosing in in-vitro fertilisation: a randomized trial.

Li HWR, Ko JKY, Lee VCY, Yung SSF, Lau EYL, Yeung WSB, Ho PC, Ng EHY.

Ultrasound Obstet Gynecol. 2019 Jul 20. doi: 10.1002/uog.20402. [Epub ahead of print]


Acute exercise does not improve immune response to HPV vaccination series in adolescents.

Bohn-Goldbaum E, Lee VY, Skinner SR, Frazer IH, Khan BA, Booy R, Edwards KM.

Papillomavirus Res. 2019 Jul 15:100178. doi: 10.1016/j.pvr.2019.100178. [Epub ahead of print] No abstract available.


Descriptive analysis of real-world medication use pattern of statins and antiplatelet agents among patients with acute coronary syndrome in Hong Kong and the USA.

Wang Y, Nichol MB, Yan BP, Wu J, Tomlinson B, Lee VW.

BMJ Open. 2019 Jul 16;9(7):e024937. doi: 10.1136/bmjopen-2018-024937.


Third-line systemic treatment in advanced/metastatic gastric cancer: a comprehensive review.

Chan WL, Lam KO, So TH, Lee VH, Kwong LD.

Ther Adv Med Oncol. 2019 Jun 29;11:1758835919859990. doi: 10.1177/1758835919859990. eCollection 2019. Review.


Comparing dyadic cognitive behavioral therapy (CBT) with dyadic integrative body-mind-spirit intervention (I-BMS) for Chinese family caregivers of lung cancer patients: a randomized controlled trial.

Xiu D, Fung YL, Lau BH, Wong DFK, Chan CHY, Ho RTH, So TH, Lam TC, Lee VH, Lee AWM, Chow SF, Lim FM, Tsang MW, Chan CLW, Chow AYM.

Support Care Cancer. 2019 Jul 6. doi: 10.1007/s00520-019-04974-z. [Epub ahead of print]


Contrasting Some Differences in Managing Advanced Unresectable Hepatocellular Carcinoma Between the East and the West.

Lee VHF, Seong J, Yoon SM, Wong TCL, Wang B, Zhang JL, Chiang CL, Ho PPY, Dawson LA.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):560-569. doi: 10.1016/j.clon.2019.06.002.


Advancing Care for Head and Neck Cancers in a Multidisciplinary Tumour Board in the East.

Lee VHF, Chan JYW, Vardhanabhuti V, Kwong DLW, Leung TW, Chan SY, Tong CC, Xu ZY, Shen L, Lee AWM.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):549-559. doi: 10.1016/j.clon.2019.05.023.


Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.

Saito T, Mihira N, Matsuba Y, Sasaguri H, Hashimoto S, Narasimhan S, Zhang B, Murayama S, Higuchi M, Lee VMY, Trojanowski JQ, Saido TC.

J Biol Chem. 2019 Jul 4. pii: jbc.RA119.009487. doi: 10.1074/jbc.RA119.009487. [Epub ahead of print]


Urinary placental growth factor in preeclampsia and fetal growth restriction: An alternative to circulating biomarkers?

Zhang K, Zen M, Popovic NL, Lee VW, Alahakoon TI.

J Obstet Gynaecol Res. 2019 Jul 1. doi: 10.1111/jog.14038. [Epub ahead of print]


Promotion of β-catenin/Foxo1 signaling ameliorates renal interstitial fibrosis.

Rao P, Pang M, Qiao X, Yu H, Wang H, Yang Y, Ren X, Hu M, Chen T, Cao Q, Wang Y, Khushi M, Zhang G, Wang YM, Heok P'ng C, Nankivell B, Lee VW, Alexander SI, Zheng G, Harris DC.

Lab Invest. 2019 Jun 26. doi: 10.1038/s41374-019-0276-z. [Epub ahead of print]


TREM2 function impedes tau seeding in neuritic plaques.

Leyns CEG, Gratuze M, Narasimhan S, Jain N, Koscal LJ, Jiang H, Manis M, Colonna M, Lee VMY, Ulrich JD, Holtzman DM.

Nat Neurosci. 2019 Jun 24. doi: 10.1038/s41593-019-0433-0. [Epub ahead of print]


Integrative Palliative Cancer Care in Hong Kong: An Overview and an Example from the East.

Lee VHF, Lam TC, Jing HM, Liu F, Zhang YS, Huang JJ, Lee AWM.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):589-594. doi: 10.1016/j.clon.2019.06.001. Epub 2019 Jun 21.


East Meets West: Convergence of the Art and Science of Oncology.

Agarwal JP, Lee VH.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):487-489. doi: 10.1016/j.clon.2019.06.003. Epub 2019 Jun 20. No abstract available.


Deep learning networks find unique mammographic differences in previous negative mammograms between interval and screen-detected cancers: a case-case study.

Hinton B, Ma L, Mahmoudzadeh AP, Malkov S, Fan B, Greenwood H, Joe B, Lee V, Kerlikowske K, Shepherd J.

Cancer Imaging. 2019 Jun 22;19(1):41. doi: 10.1186/s40644-019-0227-3.


A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation.

Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H, Turdiev A, Winkler WC, Sondermann H, Lee VT.

Elife. 2019 Jun 21;8. pii: e46313. doi: 10.7554/eLife.46313.


Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.

Lee VS, Halabi CM, Broekelmann TJ, Trackman PC, Stitziel NO, Mecham RP.

JCI Insight. 2019 Jun 18;5. pii: 127748. doi: 10.1172/jci.insight.127748.


Measuring the impact of a mandatory province-wide vaccinate-or-mask policy on healthcare worker absenteeism in British Columbia, Canada.

Murti M, Otterstatter M, Orth A, Balshaw R, Halani K, Brown PD, Hejazi S, Thompson D, Allison S, Bharmal A, Dawar M, Hoyano D, Lee V, Naus M, Pollock S, Bevanda J, Coughlin S, Fitzgerald J, Keen D, Maracle M, Sprague S, Henry B.

Vaccine. 2019 Jul 9;37(30):4008-4014. doi: 10.1016/j.vaccine.2019.06.007. Epub 2019 Jun 14.


Measuring the impact of influenza vaccination on healthcare worker absenteeism in the context of a province-wide mandatory vaccinate-or-mask policy.

Murti M, Otterstatter M, Orth A, Balshaw R, Halani K, Brown PD, Hejazi S, Thompson D, Allison S, Bharmal A, Dawar M, Hoyano D, Lee V, Naus M, Pollock S, Bevanda J, Coughlin S, Fitzgerald J, Keen D, Maracle M, Sprague S, Henry B.

Vaccine. 2019 Jul 9;37(30):4001-4007. doi: 10.1016/j.vaccine.2019.06.014. Epub 2019 Jun 14.


Oncology Healthcare Provision in Hong Kong: Viewpoint of a Clinical Oncologist.

Lee VH.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):490-491. doi: 10.1016/j.clon.2019.05.019. Epub 2019 Jun 8. No abstract available.


Chinese Medicine in Cancer Treatment - How is it Practised in the East and the West?

So TH, Chan SK, Lee VH, Chen BZ, Kong FM, Lao LX.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):578-588. doi: 10.1016/j.clon.2019.05.016. Epub 2019 Jun 6.


Gastric Cancer - From Aetiology to Management: Differences Between the East and the West.

Chan WL, Lam KO, Lee VHF, Davidson M, So TH, Li JS, Chau I, Kwong DLW.

Clin Oncol (R Coll Radiol). 2019 Aug;31(8):570-577. doi: 10.1016/j.clon.2019.05.012. Epub 2019 Jun 7.


Coarse-Grained Modelling and Temperature Effect on the Morphology of PS-b-PI Copolymer.

Chiangraeng N, Lee VS, Nimmanpipug P.

Polymers (Basel). 2019 Jun 6;11(6). pii: E1008. doi: 10.3390/polym11061008.


Responsive Polymers as Smart Nanomaterials Enable Diverse Applications.

Zhao J, Lee VE, Liu R, Priestley RD.

Annu Rev Chem Biomol Eng. 2019 Jun 7;10:361-382. doi: 10.1146/annurev-chembioeng-060718-030155.


α-Synuclein pathology in Parkinson's disease and related α-synucleinopathies.

Henderson MX, Trojanowski JQ, Lee VM.

Neurosci Lett. 2019 Jun 3;709:134316. doi: 10.1016/j.neulet.2019.134316. [Epub ahead of print] Review.


Evaluating the effectiveness of the influenza vaccine during respiratory outbreaks in Singapore's long term care facilities, 2017.

Ng Y, Nandar K, Chua LAV, Mak TM, Foo K, Muhammad IR, Low CKK, Ma S, Ooi SP, Lin RTP, James L, Lee VJM.

Vaccine. 2019 Jun 27;37(29):3925-3931. doi: 10.1016/j.vaccine.2019.03.054. Epub 2019 May 31.


Traumatic orbital third nerve palsy.

Nagendran ST, Lee V, Perry M.

Br J Oral Maxillofac Surg. 2019 May 30. pii: S0266-4356(19)30199-8. doi: 10.1016/j.bjoms.2019.01.029. [Epub ahead of print]


Beyond seeking informed consent: Upholding ethical values within the research proposal.

Lee V.

Can Oncol Nurs J. 2018 Jul 1;28(3):222-224. eCollection 2018 Summer. No abstract available.


Compassion, contact, communauté : Préserver des valeurs fondamentales traditionnelles pour répondre aux futurs défis en pratique infirmière en oncologie.

Lee V, Reilly R, Laux K, Robitaille A.

Can Oncol Nurs J. 2018 Jul 1;28(3):217-221. eCollection 2018 Summer. French. No abstract available.

Free PMC Article

Compassion, connection, community: Preserving traditional core values to meet future challenges in oncology nursing practice.

Lee V, Reilly R, Laux K, Robitaille A.

Can Oncol Nurs J. 2018 Jul 1;28(3):212-216. eCollection 2018 Summer. No abstract available.


Au-delà du formulaire de consentement éclairé : Pour des propositions de recherche pleinement éthiques.

Lee V.

Can Oncol Nurs J. 2018 Jul 1;28(3):225-227. eCollection 2018 Summer. French. No abstract available.

Free PMC Article

Racioethnic diversity in the dynamics of the vaginal microbiome during pregnancy.

Serrano MG, Parikh HI, Brooks JP, Edwards DJ, Arodz TJ, Edupuganti L, Huang B, Girerd PH, Bokhari YA, Bradley SP, Brooks JL, Dickinson MR, Drake JI, Duckworth RA 3rd, Fong SS, Glascock AL, Jean S, Jimenez NR, Khoury J, Koparde VN, Lara AM, Lee V, Matveyev AV, Milton SH, Mistry SD, Rozycki SK, Sheth NU, Smirnova E, Vivadelli SC, Wijesooriya NR, Xu J, Xu P, Chaffin DO, Sexton AL, Gravett MG, Rubens CE, Hendricks-Muñoz KD, Jefferson KK, Strauss JF 3rd, Fettweis JM, Buck GA.

Nat Med. 2019 Jun;25(6):1001-1011. doi: 10.1038/s41591-019-0465-8. Epub 2019 May 29.


The vaginal microbiome and preterm birth.

Fettweis JM, Serrano MG, Brooks JP, Edwards DJ, Girerd PH, Parikh HI, Huang B, Arodz TJ, Edupuganti L, Glascock AL, Xu J, Jimenez NR, Vivadelli SC, Fong SS, Sheth NU, Jean S, Lee V, Bokhari YA, Lara AM, Mistry SD, Duckworth RA 3rd, Bradley SP, Koparde VN, Orenda XV, Milton SH, Rozycki SK, Matveyev AV, Wright ML, Huzurbazar SV, Jackson EM, Smirnova E, Korlach J, Tsai YC, Dickinson MR, Brooks JL, Drake JI, Chaffin DO, Sexton AL, Gravett MG, Rubens CE, Wijesooriya NR, Hendricks-Muñoz KD, Jefferson KK, Strauss JF 3rd, Buck GA.

Nat Med. 2019 Jun;25(6):1012-1021. doi: 10.1038/s41591-019-0450-2. Epub 2019 May 29.


Synthesis of 2-(2-oxo-2H-chromen-4-yl)acetamides as potent acetylcholinesterase inhibitors and molecular insights into binding interactions.

Kara J, Suwanhom P, Wattanapiromsakul C, Nualnoi T, Puripattanavong J, Khongkow P, Lee VS, Gaurav A, Lomlim L.

Arch Pharm (Weinheim). 2019 Jul;352(7):e1800310. doi: 10.1002/ardp.201800310. Epub 2019 May 24.


Evaluating the Understandability and Actionability of Web-Based Education Materials for Patients Taking Non-vitamin K Oral Anticoagulants.

Yiu A, Ng KK, Lee VW, Bajorek BV.

Ther Innov Regul Sci. 2019 May 21:2168479019849878. doi: 10.1177/2168479019849878. [Epub ahead of print]


Current Status of Immunotherapies for Treating Pancreatic Cancer.

Wu AA, Jaffee E, Lee V.

Curr Oncol Rep. 2019 May 17;21(7):60. doi: 10.1007/s11912-019-0811-5. Review.


Intake of Palm Olein and Lipid Status in Healthy Adults: A Meta-Analysis.

Voon PT, Lee ST, Ng TKW, Ng YT, Yong XS, Lee VKM, Ong ASH.

Adv Nutr. 2019 Jul 1;10(4):647-659. doi: 10.1093/advances/nmy122.


A 15-year review of dengue hospitalizations in Singapore: Reducing admissions without adverse consequences, 2003 to 2017.

Ang LW, Thein TL, Ng Y, Boudville IC, Chia PY, Lee VJM, Leo YS.

PLoS Negl Trop Dis. 2019 May 15;13(5):e0007389. doi: 10.1371/journal.pntd.0007389. eCollection 2019 May.


The Fabrication of an Acrylic Repositioning Stent for Use During Intensity Modulated Radiation Therapy: A Feasibility Study.

Lee VSK, Nguyen CT, Wu J.

J Prosthodont. 2019 Jul;28(6):643-648. doi: 10.1111/jopr.13074. Epub 2019 Jun 11.


Evaluating Physician Knowledge of Commonly Prescribed Inpatient Rehabilitation Unit Discharge Medication's Costs: An Observational Study.

Capizzi AN, Kirk MN, Lee VA, Cushman DM.

Am J Phys Med Rehabil. 2019 May 8. doi: 10.1097/PHM.0000000000001219. [Epub ahead of print]


Effectiveness and cost-effectiveness of a virtual multidisciplinary stroke care clinic for community-dwelling stroke survivors and caregivers: a randomised controlled trial protocol.

Chau JPC, Lo SHS, Lee VWY, Choi KC, Shum EWC, Hung ZSS, Mok VCT, Siow EKC, Ching JYL, Lam SKY, Yeung JHM, Li SH, Lau AYL.

BMJ Open. 2019 May 10;9(5):e026500. doi: 10.1136/bmjopen-2018-026500.


Sustained sensing in potassium homeostasis: Cyclic di-AMP controls potassium uptake by KimA at the levels of expression and activity.

Gundlach J, Krüger L, Herzberg C, Turdiev A, Poehlein A, Tascón I, Weiss M, Hertel D, Daniel R, Hänelt I, Lee VT, Stülke J.

J Biol Chem. 2019 Jun 14;294(24):9605-9614. doi: 10.1074/jbc.RA119.008774. Epub 2019 May 6.


Targeted, structured text messaging to improve dietary and lifestyle behaviours for people on maintenance haemodialysis (KIDNEYTEXT): study protocol for a randomised controlled trial.

Stevenson J, Campbell KL, Brown M, Craig J, Howard K, Howell M, Khalid R, Sud K, Teixeira-Pinto A, Thiagalingam A, Tong A, Chow C, Lee VW.

BMJ Open. 2019 May 5;9(5):e023545. doi: 10.1136/bmjopen-2018-023545.


A review of biosimilar in regulations and potential impact: Hong Kong perspectives.

Lee VW, Cheng FW.

J Med Econ. 2019 May 28:1-3. doi: 10.1080/13696998.2019.1614008. [Epub ahead of print] No abstract available.


Testing relationship recognition in wild jackdaws (Corvus monedula).

Lee VE, McIvor GE, Thornton A.

Sci Rep. 2019 Apr 30;9(1):6710. doi: 10.1038/s41598-019-43247-x.


Long-term health-related burden of adult congenital heart diseases in Hong Kong.

Lee VWY, Yan BP, Fong TMC, Fung AKP, Cheng FWT.

J Med Econ. 2019 Aug;22(8):814-817. doi: 10.1080/13696998.2019.1613239. Epub 2019 May 23.


α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons.

Wu Q, Takano H, Riddle DM, Trojanowski JQ, Coulter DA, Lee VM.

J Neurosci. 2019 Jun 26;39(26):5080-5094. doi: 10.1523/JNEUROSCI.0060-19.2019. Epub 2019 Apr 29.


Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies.

Berson A, Goodman LD, Sartoris AN, Otte CG, Aykit JA, Lee VM, Trojanowski JQ, Bonini NM.

Acta Neuropathol Commun. 2019 Apr 29;7(1):65. doi: 10.1186/s40478-019-0710-x.


eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS.

Goodman LD, Prudencio M, Srinivasan AR, Rifai OM, Lee VM, Petrucelli L, Bonini NM.

Acta Neuropathol Commun. 2019 Apr 25;7(1):62. doi: 10.1186/s40478-019-0711-9.

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