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Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).

Morrison EE, Oatey K, Gallagher B, Grahamslaw J, O'Brien R, Black P, Oosthuyzen W, Lee RJ, Weir CJ, Henriksen D, Dear JW; POP Trial Investigators.

EBioMedicine. 2019 Jul 13. pii: S2352-3964(19)30448-7. doi: 10.1016/j.ebiom.2019.07.013. [Epub ahead of print]


Development of a stable single-vial liposomal formulation for vincristine.

Mao W, Wu F, Lee RJ, Lu W, Wang J.

Int J Nanomedicine. 2019 Jun 21;14:4461-4474. doi: 10.2147/IJN.S205276. eCollection 2019.


Liposomal Vitamin D3 as an Anti-aging Agent for the Skin.

Bi Y, Xia H, Li L, Lee RJ, Xie J, Liu Z, Qiu Z, Teng L.

Pharmaceutics. 2019 Jul 3;11(7). pii: E311. doi: 10.3390/pharmaceutics11070311.


Anticancer activity of polymeric nanoparticles containing linoleic acid-SN38 (LA-SN38) conjugate in a murine model of colorectal cancer.

Cheng G, Zhang X, Chen Y, Lee RJ, Wang J, Yao J, Zhang Y, Zhang C, Wang K, Yu B.

Colloids Surf B Biointerfaces. 2019 Jun 15;181:822-829. doi: 10.1016/j.colsurfb.2019.06.020. [Epub ahead of print]


Interdisciplinary Citizen Science and Design Projects for Hazard and Disaster Education.

Masterson J, Meyer M, Ghariabeh N, Hendricks M, Lee RJ, Musharrat S, Newman G, Sansom G, Zandt SV.

Int J Mass Emerg Disasters. 2019 Mar;37(1):6-24.


Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors.

Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N.

JCO Precis Oncol. 2019;3. doi: 10.1200/PO.18.00283. Epub 2019 May 10.


Chromatic adaptation from achromatic stimuli with implied color.

Lee RJ, Mather G.

Atten Percept Psychophys. 2019 Jun 14. doi: 10.3758/s13414-019-01716-5. [Epub ahead of print]


The evolution and understanding of skeletal complication endpoints in clinical trials of tumors with metastasis to the bone.

Hussain A, Lee RJ, Graff JN, Halabi S.

Crit Rev Oncol Hematol. 2019 Jul;139:108-116. doi: 10.1016/j.critrevonc.2019.04.020. Epub 2019 Apr 30. Review.


Delivery of siRNA using folate receptor-targeted pH-sensitive polymeric nanoparticles for rheumatoid arthritis therapy.

Sun X, Dong S, Li X, Yu K, Sun F, Lee RJ, Li Y, Teng L.

Nanomedicine. 2019 May 22;20:102017. doi: 10.1016/j.nano.2019.102017. [Epub ahead of print]


Current Status of MRI and PET in the NCCN Guidelines for Prostate Cancer.

Mason BR, Eastham JA, Davis BJ, Mynderse LA, Pugh TJ, Lee RJ, Ippolito JE.

J Natl Compr Canc Netw. 2019 May 1;17(5):506-513. doi: 10.6004/jnccn.2019.7306.


Multifunctional drug carrier based on PEI derivatives loaded with small interfering RNA for therapy of liver cancer.

Zhao Y, Lee RJ, Liu L, Dong S, Zhang J, Zhang Y, Yao Y, Lu J, Meng Q, Xie J, Teng L.

Int J Pharm. 2019 Jun 10;564:214-224. doi: 10.1016/j.ijpharm.2019.04.049. Epub 2019 Apr 17.


Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway.

Qi S, Guo L, Yan S, Lee RJ, Yu S, Chen S.

Acta Pharm Sin B. 2019 Mar;9(2):279-293. doi: 10.1016/j.apsb.2018.12.004. Epub 2018 Dec 15.


Delivery of Antisense Oligonucleotide LOR-2501 Using Transferrin-conjugated Polyethylenimine-based Lipid Nanoparticle.

Zheng B, Yang S, Tian Q, Xie Y, Zhang S, Lee RJ.

Anticancer Res. 2019 Apr;39(4):1785-1793. doi: 10.21873/anticanres.13285.


Reduction in risk of stroke and bleeding after left atrial appendage closure with LARIAT device in patients with increased risk of stroke and bleeding: Long term results.

Litwinowicz R, Bartus M, Kapelak B, Suwalski P, Lakkireddy D, Lee RJ, Bartus K.

Catheter Cardiovasc Interv. 2019 Mar 18. doi: 10.1002/ccd.28187. [Epub ahead of print]


Targeted and Efficient Delivery of siRNA Using Tunable Polymeric Hybrid Micelles for Tumor Therapy.

Hao F, Dong S, Yang C, Li Z, Cheng Z, Zhong L, Teng L, Meng Q, Lu J, Wu F, Xie J, Teng L, Lee RJ.

Anticancer Res. 2019 Mar;39(3):1169-1178. doi: 10.21873/anticanres.13226.


Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA.

Tan L, Sandhu S, Lee RJ, Li J, Callahan J, Ftouni S, Dhomen N, Middlehurst P, Wallace A, Raleigh J, Hatzimihalis A, Henderson MA, Shackleton M, Haydon A, Mar V, Gyorki DE, Oudit D, Dawson MA, Hicks RJ, Lorigan P, McArthur GA, Marais R, Wong SQ, Dawson SJ.

Ann Oncol. 2019 May 1;30(5):804-814. doi: 10.1093/annonc/mdz048.


Targeted Co-Delivery of siRNA and Methotrexate for Tumor Therapy via Mixed Micelles.

Hao F, Lee RJ, Yang C, Zhong L, Sun Y, Dong S, Cheng Z, Teng L, Meng Q, Lu J, Xie J, Teng L.

Pharmaceutics. 2019 Feb 21;11(2). pii: E92. doi: 10.3390/pharmaceutics11020092.


Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction.

Hardy SA, Mabotuwana NS, Murtha LA, Coulter B, Sanchez-Bezanilla S, Al-Omary MS, Senanayake T, Loering S, Starkey M, Lee RJ, Rainer PP, Hansbro PM, Boyle AJ.

PLoS One. 2019 Feb 21;14(2):e0212230. doi: 10.1371/journal.pone.0212230. eCollection 2019.


Spatial and temporal variation of three biomarkers in Mytilus edulis.

Strubbia S, Lyons BP, Lee RJ.

Mar Pollut Bull. 2019 Jan;138:322-327. doi: 10.1016/j.marpolbul.2018.09.055. Epub 2018 Nov 28.


Thiophene Derivatives as Anticancer Agents and Their Delivery to Tumor Cells Using Albumin Nanoparticles.

Cai G, Wang S, Zhao L, Sun Y, Yang D, Lee RJ, Zhao M, Zhang H, Zhou Y.

Molecules. 2019 Jan 6;24(1). pii: E192. doi: 10.3390/molecules24010192.


Folic acid receptor-targeted human serum albumin nanoparticle formulation of cabazitaxel for tumor therapy.

Sun Y, Zhao Y, Teng S, Hao F, Zhang H, Meng F, Zhao X, Zheng X, Bi Y, Yao Y, Lee RJ, Teng L.

Int J Nanomedicine. 2018 Dec 21;14:135-148. doi: 10.2147/IJN.S181296. eCollection 2019.


Rapid left atrial appendage thrombus formation before suture ligation with LARIAT.

Bartuś K, Myć J, Bartuś M, Lee RJ, Litwinowicz R, Dziewierz A, Kapelak B.

Postepy Kardiol Interwencyjnej. 2018;14(4):435-437. doi: 10.5114/aic.2018.79876. Epub 2018 Dec 11. No abstract available.


Cell-penetrating Peptide-coated Liposomes for Drug Delivery Across the Blood-Brain Barrier.

Yuan BO, Zhao Y, Dong S, Sun Y, Hao F, Xie J, Teng L, Lee RJ, Fu Y, Bi YE.

Anticancer Res. 2019 Jan;39(1):237-243. doi: 10.21873/anticanres.13103.


Demographics, Practising Arrangements, and Standards: Survey among New Zealand Dentists.

Lee RJ, Ratnayake J, Veerasamy A, Loch C, Cathro P, Brunton PA.

Int J Dent. 2018 Nov 18;2018:7675917. doi: 10.1155/2018/7675917. eCollection 2018.


Long term outcomes after left atrial appendage closure with the LARIAT device-Stroke risk reduction over five years follow-up.

Litwinowicz R, Bartus M, Burysz M, Brzeziński M, Suwalski P, Kapelak B, Vuddanda V, Lakkireddy D, Lee RJ, Trabka R, Bartus K.

PLoS One. 2018 Dec 19;13(12):e0208710. doi: 10.1371/journal.pone.0208710. eCollection 2018.


Effect of PD-L1 testing on the cost-effectiveness and budget impact of pembrolizumab for advanced urothelial carcinoma of the bladder in the United States.

Criss SD, Weaver DT, Sheehan DF, Lee RJ, Pandharipande PV, Kong CY.

Urol Oncol. 2019 Mar;37(3):180.e11-180.e18. doi: 10.1016/j.urolonc.2018.11.016. Epub 2018 Dec 6.


Risk Factors for Concomitant Collateral Ligament Injuries in Children and Adolescents With Anterior Cruciate Ligament Tears.

Lee RJ, Margalit A, Nduaguba A, Gunderson MA, Ganley TJ.

Orthop J Sports Med. 2018 Nov 21;6(11):2325967118810389. doi: 10.1177/2325967118810389. eCollection 2018 Nov.


Subxiphoid Hybrid Approach for Epicardial/Endocardial Ablation and LAA Exclusion in Patients with Persistent and Longstanding Atrial Fibrillation.

Badhwar N, Al-Dosari G, Dukes J, Lee RJ.

J Atr Fibrillation. 2018 Jun 30;11(1):2014. doi: 10.4022/jafib.2014. eCollection 2018 Jun-Jul.


The Spatial Order of Physeal Maturation in the Normal Human Knee Using Magnetic Resonance Imaging.

Margalit A, Cottrill E, Nhan D, Yu L, Tang X, Fritz J, Lee RJ.

J Pediatr Orthop. 2019 Apr;39(4):e318-e322. doi: 10.1097/BPO.0000000000001298.


Polyethylenimine-based Formulations for Delivery of Oligonucleotides.

Hao F, Li Y, Zhu J, Sun J, Marshall B, Lee RJ, Teng L, Yang Z, Xie J.

Curr Med Chem. 2019;26(13):2264-2284. doi: 10.2174/0929867325666181031094759.


Obesity and recovery of muscle strength after anterior cruciate ligament reconstruction in pediatric patients.

Lee RJ, Margalit A, Nduaguba A, Gunderson MA, Wells L.

J Orthop Surg (Hong Kong). 2018 May-Aug;26(3):2309499018806631. doi: 10.1177/2309499018806631.


Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy.

Bi Y, Lee RJ, Wang X, Sun Y, Wang M, Li L, Li C, Xie J, Teng L.

Int J Nanomedicine. 2018 Oct 4;13:5811-5822. doi: 10.2147/IJN.S173279. eCollection 2018.


Prostate cancer in transgender women.

Ingham MD, Lee RJ, MacDermed D, Olumi AF.

Urol Oncol. 2018 Dec;36(12):518-525. doi: 10.1016/j.urolonc.2018.09.011. Epub 2018 Oct 12. Review.


Antitumor effect of a liposome-encapsulated β1,4-galactosyltransferase inhibitor.

Cai G, Wang K, Qu N, Qiu P, Vlahakis JZ, Szarek WA, Lee RJ, Gao Y.

Int J Pharm. 2018 Dec 1;552(1-2):388-393. doi: 10.1016/j.ijpharm.2018.10.010. Epub 2018 Oct 6.


Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice.

Elmore MRP, Hohsfield LA, Kramár EA, Soreq L, Lee RJ, Pham ST, Najafi AR, Spangenberg EE, Wood MA, West BL, Green KN.

Aging Cell. 2018 Dec;17(6):e12832. doi: 10.1111/acel.12832. Epub 2018 Oct 2.


Ketoprofen and MicroRNA-124 Co-loaded poly (lactic-co-glycolic acid) microspheres inhibit progression of Adjuvant-induced arthritis in rats.

Yu C, Zhang X, Sun X, Long C, Sun F, Liu J, Li X, Lee RJ, Liu N, Li Y, Teng L.

Int J Pharm. 2018 Dec 1;552(1-2):148-153. doi: 10.1016/j.ijpharm.2018.09.063. Epub 2018 Sep 27.


Accuracy and reliability of the expected root position setup methodology to evaluate root position during orthodontic treatment.

Lee RJ, Pi S, Park J, Devgon D, Nelson G, Hatcher D, Oberoi S.

Am J Orthod Dentofacial Orthop. 2018 Oct;154(4):583-595. doi: 10.1016/j.ajodo.2018.05.010.


Social desirability, deceptive reporting, and awareness of problematic aggression in intermittent explosive disorder compared with non-aggressive healthy and psychiatric controls.

Steakley-Freeman DM, Lee RJ, McCloskey MS, Coccaro EF.

Psychiatry Res. 2018 Dec;270:20-25. doi: 10.1016/j.psychres.2018.08.064. Epub 2018 Aug 18.


Comorbidity of personality disorder with intermittent explosive disorder.

Coccaro EF, Shima CK, Lee RJ.

J Psychiatr Res. 2018 Nov;106:15-21. doi: 10.1016/j.jpsychires.2018.08.013. Epub 2018 Aug 10.


An overview of current and emerging devices for percutaneous left atrial appendage closure.

Chow DHF, Wong YH, Park JW, Lam YY, De Potter T, Rodés-Cabau J, Asmarats L, Sandri M, Sideris E, McCaw T, Lee RJ, Sievert H, Søndergaard L, De Backer O.

Trends Cardiovasc Med. 2019 May;29(4):228-236. doi: 10.1016/j.tcm.2018.08.008. Epub 2018 Aug 30. Review.


Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Machine Learning for Molecular Recognition of Myocardial Infarction.

Margulis K, Zhou Z, Fang Q, Sievers RE, Lee RJ, Zare RN.

Anal Chem. 2018 Oct 16;90(20):12198-12206. doi: 10.1021/acs.analchem.8b03410. Epub 2018 Sep 25.


Clinical translation of immunoliposomes for cancer therapy: recent perspectives.

Wang D, Sun Y, Liu Y, Meng F, Lee RJ.

Expert Opin Drug Deliv. 2018 Sep;15(9):893-903. doi: 10.1080/17425247.2018.1517747. Epub 2018 Sep 12. Review.


10-Min 3D Turbo Spin Echo MRI of the Knee in Children: Arthroscopy-Validated Accuracy for the Diagnosis of Internal Derangement.

Fritz J, Ahlawat S, Fritz B, Thawait GK, Stern SE, Raithel E, Klyce W, Lee RJ.

J Magn Reson Imaging. 2019 Jun;49(7):e139-e151. doi: 10.1002/jmri.26241. Epub 2018 Aug 24.


T7 Peptide-Conjugated Lipid Nanoparticles for Dual Modulation of Bcl-2 and Akt-1 in Lung and Cervical Carcinomas.

Cheng X, Yu D, Cheng G, Yung BC, Liu Y, Li H, Kang C, Fang X, Tian S, Zhou X, Liu Q, Lee RJ.

Mol Pharm. 2018 Oct 1;15(10):4722-4732. doi: 10.1021/acs.molpharmaceut.8b00696. Epub 2018 Sep 7.


Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.

Al-Shahi Salman R, Frantzias J, Lee RJ, Lyden PD, Battey TWK, Ayres AM, Goldstein JN, Mayer SA, Steiner T, Wang X, Arima H, Hasegawa H, Oishi M, Godoy DA, Masotti L, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Jang DK, Davalos A, Castillo J, Yao X, Claassen J, Volbers B, Kazui S, Okada Y, Fujimoto S, Toyoda K, Li Q, Khoury J, Delgado P, Sabín JÁ, Hernández-Guillamon M, Prats-Sánchez L, Cai C, Kate MP, McCourt R, Venkatasubramanian C, Diringer MN, Ikeda Y, Worthmann H, Ziai WC, d'Esterre CD, Aviv RI, Raab P, Murai Y, Zazulia AR, Butcher KS, Seyedsaadat SM, Grotta JC, Martí-Fàbregas J, Montaner J, Broderick J, Yamamoto H, Staykov D, Connolly ES, Selim M, Leira R, Moon BH, Demchuk AM, Di Napoli M, Fujii Y, Anderson CS, Rosand J; VISTA-ICH Collaboration; ICH Growth Individual Patient Data Meta-analysis Collaborators.

Lancet Neurol. 2018 Oct;17(10):885-894. doi: 10.1016/S1474-4422(18)30253-9. Epub 2018 Aug 14. Erratum in: Lancet Neurol. 2018 Sep 19;:.


Targeted Liposomes for siRNA Delivery to Cancer.

Eloy JO, Petrilli R, Raspantini GL, Lee RJ.

Curr Pharm Des. 2018;24(23):2664-2672. doi: 10.2174/1381612824666180807121935.


Pericardial Delivery of Biological Agents: The Next Frontier?

Govea A, Lee RJ.

JACC Basic Transl Sci. 2017 Oct 30;2(5):610-612. doi: 10.1016/j.jacbts.2017.09.007. eCollection 2017 Oct. No abstract available.


An Abbreviated Scale for the Assessment of Skeletal Bone Age Using Radiographs of the Knee.

Tang X, Lu Y, Pang M, Nhan DT, Klyce W, Fritz J, Lee RJ.

Orthopedics. 2018 Sep 1;41(5):e676-e680. doi: 10.3928/01477447-20180724-03. Epub 2018 Jul 27.


Epidemiological Patterns of Alternative Racquet-Sport Injuries in the United States, 1997-2016.

Nhan DT, Klyce W, Lee RJ.

Orthop J Sports Med. 2018 Jul 23;6(7):2325967118786237. doi: 10.1177/2325967118786237. eCollection 2018 Jul.

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