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Multivariable analysis of factors associated with USMLE scores across U.S. medical schools.

Ghaffari-Rafi A, Lee RE, Fang R, Miles JD.

BMC Med Educ. 2019 May 20;19(1):154. doi: 10.1186/s12909-019-1605-z.


Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections.

Iverson A, Meyer CJ, Vogel P, Waidyarachchi S, Das N, Bruhn DF, Poole A, Butler MM, Bowlin TL, Lee RE, Rosch JW.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02096-18. doi: 10.1128/AAC.02096-18. Print 2019 May.


A network-centric approach to drugging TNF-induced NF-κB signaling.

Pabon NA, Zhang Q, Cruz JA, Schipper DL, Camacho CJ, Lee REC.

Nat Commun. 2019 Feb 26;10(1):860. doi: 10.1038/s41467-019-08802-0.


Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis.

Berical A, Lee RE, Randell SH, Hawkins F.

Front Pharmacol. 2019 Feb 8;10:74. doi: 10.3389/fphar.2019.00074. eCollection 2019. Review.


Sustainability via Active Garden Education: Translating Policy to Practice in Early Care and Education.

Lee RE, Soltero EG, Ledoux TA, Sahnoune I, Saavadra F, Mama SK, McNeill LH.

J Sch Health. 2019 Apr;89(4):257-266. doi: 10.1111/josh.12734. Epub 2019 Feb 5.


Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice.

Rathi C, Lukka PB, Wagh S, Lee RE, Lenaerts AJ, Braunstein M, Hickey A, Gonzalez-Juarrero M, Meibohm B.

Tuberculosis (Edinb). 2019 Jan;114:119-122. doi: 10.1016/ Epub 2018 Dec 31.


Incidence of Capillary Leak Syndrome as an Adverse Effect of Drugs in Cancer Patients: A Systematic Review and Meta-Analysis.

Jeong GH, Lee KH, Lee IR, Oh JH, Kim DW, Shin JW, Kronbichler A, Eisenhut M, van der Vliet HJ, Abdel-Rahman O, Stubbs B, Solmi M, Veronese N, Dragioti E, Koyanagi A, Radua J, Shin JI.

J Clin Med. 2019 Jan 26;8(2). pii: E143. doi: 10.3390/jcm8020143.


Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.

Zhang M, Prior AM, Maddox MM, Shen WJ, Hevener KE, Bruhn DF, Lee RB, Singh AP, Reinicke J, Simmons CJ, Hurdle JG, Lee RE, Sun D.

ACS Omega. 2018 Dec 31;3(12):18343-18360. doi: 10.1021/acsomega.8b03174. Epub 2018 Dec 26.


Design and methodology of a cluster-randomized trial in early care and education centers to meet physical activity guidelines: Sustainability via Active Garden Education (SAGE).

Lee RE, Lorenzo E, Szeszulski J, Arriola A, Bruening M, Estabrooks PA, Hill J, Marsiglia FF, O'Connor T, Pollins KS, Shaibi GQ, Soltero E, Todd M.

Contemp Clin Trials. 2019 Feb;77:8-18. doi: 10.1016/j.cct.2018.12.003. Epub 2018 Dec 12.


The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis.

Brewer CT, Yang L, Edwards A, Lu Y, Low J, Wu J, Lee RE, Chen T.

Toxicol Sci. 2019 Mar 1;168(1):209-224. doi: 10.1093/toxsci/kfy294.


Advancing Translational Science for Pulmonary Nontuberculous Mycobacterial Infections. A Road Map for Research.

Daniel-Wayman S, Abate G, Barber DL, Bermudez LE, Coler RN, Cynamon MH, Daley CL, Davidson RM, Dick T, Floto RA, Henkle E, Holland SM, Jackson M, Lee RE, Nuermberger EL, Olivier KN, Ordway DJ, Prevots DR, Sacchettini JC, Salfinger M, Sassetti CM, Sizemore CF, Winthrop KL, Zelazny AM.

Am J Respir Crit Care Med. 2019 Apr 15;199(8):947-951. doi: 10.1164/rccm.201807-1273PP. No abstract available.


Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis.

Vaddady PK, Trivedi A, Rathi C, Madhura DB, Liu J, Lee RE, Meibohm B.

Eur J Pharm Sci. 2019 Jan 15;127:233-239. doi: 10.1016/j.ejps.2018.11.006. Epub 2018 Nov 9.


Systemic Capillary Leak Syndrome (Clarkson Syndrome) in Cancer Patients: A Systematic Review.

Shin JI, Lee KH, Lee IR, Oh JH, Kim DW, Shin JW, Eo TS, Kronbichler A, Eisenhut M, van der Vliet HJ.

J Clin Med. 2018 Nov 6;7(11). pii: E418. doi: 10.3390/jcm7110418.


A therapeutic approach to pantothenate kinase associated neurodegeneration.

Sharma LK, Subramanian C, Yun MK, Frank MW, White SW, Rock CO, Lee RE, Jackowski S.

Nat Commun. 2018 Oct 23;9(1):4399. doi: 10.1038/s41467-018-06703-2.


Physical activity and exercise during preoperative pancreatic cancer treatment.

Parker NH, Ngo-Huang A, Lee RE, O'Connor DP, Basen-Engquist KM, Petzel MQB, Wang X, Xiao L, Fogelman DR, Schadler KL, Simpson RJ, Fleming JB, Lee JE, Varadhachary GR, Sahai SK, Katz MHG.

Support Care Cancer. 2019 Jun;27(6):2275-2284. doi: 10.1007/s00520-018-4493-6. Epub 2018 Oct 17.


Nitric oxide metabolites in hypoxia, freezing, and hibernation of the wood frog, Rana sylvatica.

Williams BL, Wiebler JM, Lee RE Jr, Costanzo JP.

J Comp Physiol B. 2018 Nov;188(6):957-966. doi: 10.1007/s00360-018-1182-1. Epub 2018 Sep 12.


Evaluation of Parallel Tempering to Accelerate Bayesian Parameter Estimation in Systems Biology.

Gupta S, Hainsworth L, Hogg JS, Lee REC, Faeder JR.

Proc Euromicro Int Conf Parallel Distrib Netw Based Process. 2018 Mar;2018:690-697. doi: 10.1109/PDP2018.2018.00114. Epub 2018 Jun 7.


New β-lactam - Tetramic acid hybrids show promising antibacterial activities.

Cherian PT, Cheramie MN, Marreddy RKR, Fernando DM, Hurdle JG, Lee RE.

Bioorg Med Chem Lett. 2018 Oct 1;28(18):3105-3112. doi: 10.1016/j.bmcl.2018.07.018. Epub 2018 Jul 17.


The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase.

Griffith EC, Wallace MJ, Wu Y, Kumar G, Gajewski S, Jackson P, Phelps GA, Zheng Z, Rock CO, Lee RE, White SW.

Front Microbiol. 2018 Jul 17;9:1369. doi: 10.3389/fmicb.2018.01369. eCollection 2018.


Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype.

Weaver AJ, Peters TR, Tripet B, Van Vuren A, Rakesh, Lee RE, Copié V, Teintze M.

Sci Rep. 2018 Jun 29;8(1):9850. doi: 10.1038/s41598-018-28283-3.


Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors.

Singh M, Warita K, Warita T, Faeder JR, Lee REC, Sant S, Oltvai ZN.

Sci Rep. 2018 Jun 20;8(1):9388. doi: 10.1038/s41598-018-27266-8.


A pilot test of the GoWoman weight management intervention for women with mobility impairments in the online virtual world of Second Life®.

Nosek MA, Robinson-Whelen S, Ledoux TA, Hughes RB, O'Connor DP, Lee RE, Goe R, Silveira SL, Markley R, Nosek TM; GoWoman Consortium.

Disabil Rehabil. 2018 Jun 11:1-12. doi: 10.1080/09638288.2018.1473511. [Epub ahead of print]


In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.

Brown Gandt A, Griffith EC, Lister IM, Billings LL, Han A, Tangallapally R, Zhao Y, Singh AP, Lee RE, LaFleur MD.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00424-18. doi: 10.1128/AAC.00424-18. Print 2018 Aug.


Management of tibioperoneal trunk aneurysm in a patient with Behçet disease.

Hamouda M, Dakour Aridi H, Lee RE, Dhaliwal JS, Malas MB.

J Vasc Surg Cases Innov Tech. 2017 Dec 27;4(1):15-18. doi: 10.1016/j.jvscit.2017.10.009. eCollection 2018 Mar.


Urea hydrolysis by gut bacteria in a hibernating frog: evidence for urea-nitrogen recycling in Amphibia.

Wiebler JM, Kohl KD, Lee RE Jr, Costanzo JP.

Proc Biol Sci. 2018 May 16;285(1878). pii: 20180241. doi: 10.1098/rspb.2018.0241.


CINPA1 binds directly to constitutive androstane receptor and inhibits its activity.

Cherian MT, Chai SC, Wright WC, Singh A, Alexandra Casal M, Zheng J, Wu J, Lee RE, Griffin PR, Chen T.

Biochem Pharmacol. 2018 Jun;152:211-223. doi: 10.1016/j.bcp.2018.03.029. Epub 2018 Mar 31.


Aminomethyl Spectinomycins as Therapeutics for Drug-Resistant Gonorrhea and Chlamydia Coinfections.

Butler MM, Waidyarachchi SL, Connolly KL, Jerse AE, Chai W, Lee RE, Kohlhoff SA, Shinabarger DL, Bowlin TL.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00325-18. doi: 10.1128/AAC.00325-18. Print 2018 May.


Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B Analogs.

Tsutsumi LS, Elmore JM, Dang UT, Wallace MJ, Marreddy R, Lee RB, Tan GT, Hurdle JG, Lee RE, Sun D.

ACS Comb Sci. 2018 Mar 12;20(3):172-185. doi: 10.1021/acscombsci.7b00189. Epub 2018 Feb 20.


NF-κB-Chromatin Interactions Drive Diverse Phenotypes by Modulating Transcriptional Noise.

Wong VC, Bass VL, Bullock ME, Chavali AK, Lee REC, Mothes W, Gaudet S, Miller-Jensen K.

Cell Rep. 2018 Jan 16;22(3):585-599. doi: 10.1016/j.celrep.2017.12.080.


Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.

Shadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, Kiplin Guy R, Shelat AA, Potter PM.

Bioorg Med Chem. 2018 Jan 1;26(1):25-36. doi: 10.1016/j.bmc.2017.10.042. Epub 2017 Nov 4.


NF-κB Dynamics Discriminate between TNF Doses in Single Cells.

Zhang Q, Gupta S, Schipper DL, Kowalczyk GJ, Mancini AE, Faeder JR, Lee REC.

Cell Syst. 2017 Dec 27;5(6):638-645.e5. doi: 10.1016/j.cels.2017.10.011. Epub 2017 Nov 8.


Clinical Presentation, Management, and Prognostic Factors of Idiopathic Systemic Capillary Leak Syndrome: A Systematic Review.

Eo TS, Chun KJ, Hong SJ, Kim JY, Lee IR, Lee KH, Eisenhut M, Kronbichler A, Shin JI.

J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):609-618. doi: 10.1016/j.jaip.2017.07.021. Epub 2017 Sep 19.


Evaluating the effectiveness of physician counseling to promote physical activity in Mexico: an effectiveness-implementation hybrid study.

Galaviz KI, Estabrooks PA, Ulloa EJ, Lee RE, Janssen I, López Y Taylor J, Ortiz-Hernández L, Lévesque L.

Transl Behav Med. 2017 Dec;7(4):731-740. doi: 10.1007/s13142-017-0524-y.


Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.

Miao Y, Tenor JL, Toffaletti DL, Maskarinec SA, Liu J, Lee RE, Perfect JR, Brennan RG.

MBio. 2017 Jul 25;8(4). pii: e00643-17. doi: 10.1128/mBio.00643-17.


FDA Regulatory Perspectives for Studies on Hemodialysis Vascular Access.

Hurst FP, Lee RE, Thompson AM, Pullin BD, Silverstein DM.

Clin J Am Soc Nephrol. 2018 Mar 7;13(3):513-518. doi: 10.2215/CJN.02900317. Epub 2017 Jul 24.


Parenting Practices and Children's Physical Activity: An Integrative Review.

Hutchens A, Lee RE.

J Sch Nurs. 2018 Feb;34(1):68-85. doi: 10.1177/1059840517714852. Epub 2017 Jun 20. Review.


Synthesis and Evaluation of Thiazolidine Amide and N-Thiazolyl Amide Fluoroquinolone Derivatives.

Garza I, Wallace MJ, Fernando D, Singh A, Lee RE, Gerding JS, Franklin C, Yendapally R.

Arch Pharm (Weinheim). 2017 Jun;350(6). doi: 10.1002/ardp.201700029. Epub 2017 Apr 21.


Sustainability via Active Garden Education (SAGE): results from two feasibility pilot studies.

Lee RE, Parker NH, Soltero EG, Ledoux TA, Mama SK, McNeill L.

BMC Public Health. 2017 Mar 10;17(1):242. doi: 10.1186/s12889-017-4163-5.


A Mobile, Avatar-Based App for Improving Body Perceptions Among Adolescents: A Pilot Test.

Lyles AA, Amresh A, Huberty J, Todd M, Lee RE.

JMIR Serious Games. 2017 Mar 2;5(1):e4. doi: 10.2196/games.6354.


Characterization of the School Neighborhood Food Environment in Three Mexican Cities.

Soltero EG, Ortiz Hernández L, Jauregui E, Lévesque L, Lopez Y Taylor J, Barquera S, Lee RE.

Ecol Food Nutr. 2017 Mar-Apr;56(2):139-151. doi: 10.1080/03670244.2016.1274261. Epub 2017 Jan 19.


Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions.

Liu J, Bruhn DF, Lee RB, Zheng Z, Janusic T, Scherbakov D, Scherman MS, Boshoff HI, Das S, Rakesh, Waidyarachchi SL, Brewer TA, Gracia B, Yang L, Bollinger J, Robertson GT, Meibohm B, Lenaerts AJ, Ainsa J, Böttger EC, Lee RE.

ACS Infect Dis. 2017 Jan 13;3(1):72-88. doi: 10.1021/acsinfecdis.6b00158. Epub 2016 Nov 11.


The impact of religiosity on dietary habits and physical activity in minority women participating in the Health is Power (HIP) study.

Ansari S, Soltero EG, Lorenzo E, Lee RE.

Prev Med Rep. 2016 Dec 21;5:210-213. doi: 10.1016/j.pmedr.2016.12.012. eCollection 2017 Mar.


A Fluorescent Probe for Detecting Mycobacterium tuberculosis and Identifying Genes Critical for Cell Entry.

Yang D, Ding F, Mitachi K, Kurosu M, Lee RE, Kong Y.

Front Microbiol. 2016 Dec 20;7:2021. doi: 10.3389/fmicb.2016.02021. eCollection 2016.


RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host.

Honsa ES, Cooper VS, Mhaissen MN, Frank M, Shaker J, Iverson A, Rubnitz J, Hayden RT, Lee RE, Rock CO, Tuomanen EI, Wolf J, Rosch JW.

MBio. 2017 Jan 3;8(1). pii: e02124-16. doi: 10.1128/mBio.02124-16.


NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor.

Lee RE, Qasaimeh MA, Xia X, Juncker D, Gaudet S.

Sci Rep. 2016 Dec 22;6:39519. doi: 10.1038/srep39519.


Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models.

Robertson GT, Scherman MS, Bruhn DF, Liu J, Hastings C, McNeil MR, Butler MM, Bowlin TL, Lee RB, Lee RE, Lenaerts AJ.

J Antimicrob Chemother. 2017 Mar 1;72(3):770-777. doi: 10.1093/jac/dkw467.


Translational PK/PD of anti-infective therapeutics.

Rathi C, Lee RE, Meibohm B.

Drug Discov Today Technol. 2016 Sep - Dec;21-22:41-49. doi: 10.1016/j.ddtec.2016.08.004. Epub 2016 Oct 28. Review.


Demystifying the cytokine network: Mathematical models point the way.

Morel PA, Lee REC, Faeder JR.

Cytokine. 2017 Oct;98:115-123. doi: 10.1016/j.cyto.2016.11.013. Epub 2016 Dec 3. Review.


Contribution of Psychosocial Factors to Physical Activity in Women of Color in the Saving Lives Staying Active (SALSA) Study.

Mama SK, McNeill LH, Soltero EG, Orlando Edwards R, Lee RE.

J Aging Phys Act. 2017 Jul;25(3):351-359. doi: 10.1123/japa.2015-0239. Epub 2017 Jun 28.


Causes of death in 184 patients with type 1 Gaucher disease from the United States who were never treated with enzyme replacement therapy.

Weinreb NJ, Barbouth DS, Lee RE.

Blood Cells Mol Dis. 2018 Feb;68:211-217. doi: 10.1016/j.bcmd.2016.10.002. Epub 2016 Oct 24.

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