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Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA.

Dukovski D, Villella A, Bastos C, King R, Finley D, Kelly JW, Morimoto RI, Hartl FU, Munoz B, Lee PS, Zecevic M, Miller JP.

J Cyst Fibros. 2020 Feb 14. pii: S1569-1993(20)30052-7. doi: 10.1016/j.jcf.2020.02.006. [Epub ahead of print]


Photothermal actuated origamis based on graphene oxide-cellulose programmable bilayers.

Gao D, Lin MF, Xiong J, Li S, Lou SN, Liu Y, Ciou JH, Zhou X, Lee PS.

Nanoscale Horiz. 2020 Feb 17. doi: 10.1039/c9nh00719a. [Epub ahead of print]


Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.

Han W, Ma X, Balibar CJ, Baxter Rath CM, Benton B, Bermingham A, Casey F, Chie-Leon B, Cho MK, Frank AO, Frommlet A, Ho CM, Lee PS, Li M, Lingel A, Ma S, Merritt H, Ornelas E, De Pascale G, Prathapam R, Prosen KR, Rasper D, Ruzin A, Sawyer WS, Shaul J, Shen X, Shia S, Steffek M, Subramanian S, Vo J, Wang F, Wartchow C, Uehara T.

J Am Chem Soc. 2020 Feb 17. doi: 10.1021/jacs.9b13530. [Epub ahead of print]


Rectifying ionic current with ionoelastomers.

Gao D, Lee PS.

Science. 2020 Feb 14;367(6479):735-736. doi: 10.1126/science.aba6270. No abstract available.


Intraperitoneal chemotherapy following neoadjuvant chemotherapy and optimal interval tumor reductive surgery for advanced ovarian cancer.

Bixel K, Vetter M, Davidson B, Berchuck A, Cohn D, Copeland L, Fowler JM, Havrilesky L, Lee PS, O'Malley DM, Salani R, Valea F, Alvarez Secord A, Backes F.

Gynecol Oncol. 2020 Jan 11. pii: S0090-8258(19)31837-2. doi: 10.1016/j.ygyno.2019.12.016. [Epub ahead of print]


Uncovering the Indium Filament Revolution in Transparent Bipolar ITO/SiOx/ITO Resistive Switching Memories.

Qian K, Han X, Li H, Chen T, Lee PS.

ACS Appl Mater Interfaces. 2020 Jan 29;12(4):4579-4585. doi: 10.1021/acsami.9b16325. Epub 2020 Jan 13.


Water-Processable, Stretchable, Self-Healable, Thermally Stable, and Transparent Ionic Conductors for Actuators and Sensors.

Lee J, Tan MWM, Parida K, Thangavel G, Park SA, Park T, Lee PS.

Adv Mater. 2020 Feb;32(7):e1906679. doi: 10.1002/adma.201906679. Epub 2019 Dec 20.


Hong Kong domestic health spending: financial years 1989/90 to 2016/17.

Lee PY, Johnston JM, Lee PSL, Lee YH, Poon KKY, Lam DWS, Yeung AYT, Lam K, Ma ESK.

Hong Kong Med J. 2019 Oct;25 Suppl 6(5):1-24. No abstract available.


Curious case of gut dysmotility.

Lee PS, Jopson L, Needham SJ, Mountford CG, Thompson NP.

Gut. 2019 Nov 8. pii: gutjnl-2019-319840. doi: 10.1136/gutjnl-2019-319840. [Epub ahead of print] No abstract available.


Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms.

Jones AK, Caughlan RE, Woods AL, Uehara K, Xie L, Barnes SW, Walker JR, Thompson KV, Ranjitkar S, Lee PS, Dean CR.

Antimicrob Agents Chemother. 2019 Dec 20;64(1). pii: e01490-19. doi: 10.1128/AAC.01490-19. Print 2019 Dec 20.


Adzuki Bean Water Extract Attenuates Obesity by Modulating M2/M1 Macrophage Polarization and Gut Microbiota Composition.

Lee PS, Teng CY, Hsieh KF, Chiou YS, Wu JC, Lu TJ, Pan MH.

Mol Nutr Food Res. 2019 Dec;63(23):e1900626. doi: 10.1002/mnfr.201900626. Epub 2019 Oct 9.


Progress on wearable triboelectric nanogenerators in shapes of fiber, yarn, and textile.

Xiong J, Lee PS.

Sci Technol Adv Mater. 2019 Jul 31;20(1):837-857. doi: 10.1080/14686996.2019.1650396. eCollection 2019. Review.


Patient-centred and not disease-focused: a review of guidelines and multimorbidity.

Ong KY, Lee PSS, Lee ES.

Singapore Med J. 2019 Sep 6. doi: 10.11622/smedj.2019109. [Epub ahead of print]


Prognostic impact of stress echocardiography with discordant stress electrocardiography in patients with suspected coronary artery disease.

Chai SC, Teo HK, Lee PS, Kam CJW, Tong KL.

Singapore Med J. 2019 Sep 6. doi: 10.11622/smedj.2019105. [Epub ahead of print]


Interaction of Copper Phthalocyanine with Nitrogen Dioxide and Ammonia Investigation Using X-ray Absorption Spectroscopy and Chemiresistive Gas Measurements.

Chia LS, Du YH, Palale S, Lee PS.

ACS Omega. 2019 Jun 17;4(6):10388-10395. doi: 10.1021/acsomega.8b02108. eCollection 2019 Jun 30.


Patient preferences for attributes of primary surgical debulking versus neoadjuvant chemotherapy for treatment of newly diagnosed ovarian cancer.

Havrilesky LJ, Yang JC, Lee PS, Secord AA, Ehrisman JA, Davidson B, Berchuck A, Darcy KM, Maxwell GL, Reed SD.

Cancer. 2019 Dec 15;125(24):4399-4406. doi: 10.1002/cncr.32447. Epub 2019 Aug 27.


Advances in self-healing supramolecular soft materials and nanocomposites.

Thangavel G, Tan MWM, Lee PS.

Nano Converg. 2019 Aug 15;6(1):29. doi: 10.1186/s40580-019-0199-9. Review.


Ti3 C2 MXene Paper for the Effective Adsorption and Controllable Release of Aroma Molecules.

Ciou JH, Li S, Lee PS.

Small. 2019 Sep;15(38):e1903281. doi: 10.1002/smll.201903281. Epub 2019 Aug 7.


Leaf-inspired multiresponsive MXene-based actuator for programmable smart devices.

Cai G, Ciou JH, Liu Y, Jiang Y, Lee PS.

Sci Adv. 2019 Jul 12;5(7):eaaw7956. doi: 10.1126/sciadv.aaw7956. eCollection 2019 Jul.


Recapitulating bone development events in a customised bioreactor through interplay of oxygen tension, medium pH, and systematic differentiation approaches.

Lee PS, Hess R, Friedrichs J, Haenchen V, Eckert H, Cuniberti G, Rancourt D, Krawetz R, Hintze V, Gelinsky M, Scharnweber D.

J Tissue Eng Regen Med. 2019 Sep;13(9):1672-1684. doi: 10.1002/term.2921. Epub 2019 Jul 15.


Extremely stretchable and self-healing conductor based on thermoplastic elastomer for all-three-dimensional printed triboelectric nanogenerator.

Parida K, Thangavel G, Cai G, Zhou X, Park S, Xiong J, Lee PS.

Nat Commun. 2019 May 14;10(1):2158. doi: 10.1038/s41467-019-10061-y.


Associations between lymphovascular space invasion, nodal recurrence, and survival in patients with surgical stage I endometrioid endometrial adenocarcinoma.

Veade AE, Foote J, Ehrisman J, Broadwater G, Davidson BA, Lee PS, Secord AA, Berchuck A, Havrilesky LJ.

World J Surg Oncol. 2019 May 10;17(1):80. doi: 10.1186/s12957-019-1620-x.


Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK.

ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.


Minocycline treatment for pulmonary Mycobacterium avium complex disease based on pharmacokinetics/pharmacodynamics and Bayesian framework mathematical models.

Ruth MM, Magombedze G, Gumbo T, Bendet P, Sangen JJN, Zweijpfenning S, Hoefsloot W, Pennings L, Koeken VACM, Wertheim HFL, Lee PS, van Ingen J, Deshpande D.

J Antimicrob Chemother. 2019 Jul 1;74(7):1952-1961. doi: 10.1093/jac/dkz143.


The Interaction between Sex and Hyperlipidemia on Gout Risk Is Modulated by HLA-B Polymorphic Variants in Adult Taiwanese.

Hsu TW, Lee PS, Nfor ON, Lee CL, Chen PH, Tantoh DM, Lin LY, Chou MC, Lee YC, Liaw YP.

Genes (Basel). 2019 Mar 25;10(3). pii: E246. doi: 10.3390/genes10030246.


Inter Partes Review: Patent Killer No More?

Chen FC, Lee PS.

Trends Biotechnol. 2019 Jul;37(7):680-683. doi: 10.1016/j.tibtech.2019.02.006. Epub 2019 Mar 16.


A pilot study of lower extremity lymphedema, lower extremity function, and quality of life in women after minimally invasive endometrial cancer staging surgery.

Watson CH, Lopez-Acevedo M, Broadwater G, Kim AH, Ehrisman J, Davidson BA, Lee PS, Valea F, Berchuck A, Havrilesky LJ.

Gynecol Oncol. 2019 May;153(2):399-404. doi: 10.1016/j.ygyno.2019.02.021. Epub 2019 Mar 15.


Once-a-week tigecycline for the treatment of drug-resistant TB.

Deshpande D, Magombedze G, Srivastava S, Bendet P, Lee PS, Cirrincione KN, Martin KR, Dheda K, Gumbo T.

J Antimicrob Chemother. 2019 Jun 1;74(6):1607-1617. doi: 10.1093/jac/dkz061.


Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy.

Lee PS, Gao N, Dike M, Shkilnyy O, Me R, Zhang Y, Yu FX.

Diabetes. 2019 Apr;68(4):807-818. doi: 10.2337/db18-1172. Epub 2019 Jan 24.


Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination.

Huang H, Meegalla SK, Lanter JC, Winters MP, Zhao S, Littrell J, Qi J, Rady B, Lee PS, Liu J, Martin T, Lam WW, Xu F, Lim HK, Wilde T, Silva J, Otieno M, Pocai A, Player MR.

ACS Med Chem Lett. 2018 Dec 3;10(1):16-21. doi: 10.1021/acsmedchemlett.8b00444. eCollection 2019 Jan 10.


Minocycline Immunomodulates via Sonic Hedgehog Signaling and Apoptosis and Has Direct Potency Against Drug-Resistant Tuberculosis.

Deshpande D, Pasipanodya JG, Srivastava S, Martin KR, Athale S, van Zyl J, Antiabong J, Koeuth T, Lee PS, Dheda K, Gumbo T.

J Infect Dis. 2019 Feb 23;219(6):975-985. doi: 10.1093/infdis/jiy587.


Garcinol Reduces Obesity in High-Fat-Diet-Fed Mice by Modulating Gut Microbiota Composition.

Lee PS, Teng CY, Kalyanam N, Ho CT, Pan MH.

Mol Nutr Food Res. 2019 Jan;63(2):e1800390. doi: 10.1002/mnfr.201800390. Epub 2018 Dec 12. Erratum in: Mol Nutr Food Res. 2019 Jun;63(11):e1970025.


The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis.

Srivastava S, Deshpande D, Nuermberger E, Lee PS, Cirrincione K, Dheda K, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S336-S341. doi: 10.1093/cid/ciy626.


Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.

Deshpande D, Pasipanodya JG, Mpagama SG, Bendet P, Srivastava S, Koeuth T, Lee PS, Bhavnani SM, Ambrose PG, Thwaites G, Heysell SK, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S293-S302. doi: 10.1093/cid/ciy611.


d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal.

Deshpande D, Alffenaar JC, Köser CU, Dheda K, Chapagain ML, Simbar N, Schön T, Sturkenboom MGG, McIlleron H, Lee PS, Koeuth T, Mpagama SG, Banu S, Foongladda S, Ogarkov O, Pholwat S, Houpt ER, Heysell SK, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S308-S316. doi: 10.1093/cid/ciy624.


Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.

Deshpande D, Pasipanodya JG, Mpagama SG, Srivastava S, Bendet P, Koeuth T, Lee PS, Heysell SK, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S317-S326. doi: 10.1093/cid/ciy609.


Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis.

Deshpande D, Srivastava S, Nuermberger E, Koeuth T, Martin KR, Cirrincione KN, Lee PS, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S342-S348. doi: 10.1093/cid/ciy612.


Hong Kong domestic health spending: financial years 1989/90 to 2014/15.

Lee PY, Johnston JM, Lee PS, Lee YH, Poon KK, Lam DW, Yeung AY, Ma ES.

Hong Kong Med J. 2018 Oct;24 Suppl 8:2-24. No abstract available.


Rapid Prototyping of Polymer-Based Rolled-Up Microfluidic Devices.

Arayanarakool R, See HH, Marshall SD, Virik NS, Wang H, Lee PS, Chen PCY.

Micromachines (Basel). 2018 Oct 13;9(10). pii: E516. doi: 10.3390/mi9100516.


Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of β-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression.

Ranjitkar S, Jones AK, Mostafavi M, Zwirko Z, Iartchouk O, Barnes SW, Walker JR, Willis TW, Lee PS, Dean CR.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01718-18. doi: 10.1128/AAC.01718-18. Print 2019 Feb.


A Stretchable and Self-Healing Energy Storage Device Based on Mechanically and Electrically Restorative Liquid-Metal Particles and Carboxylated Polyurethane Composites.

Park S, Thangavel G, Parida K, Li S, Lee PS.

Adv Mater. 2019 Jan;31(1):e1805536. doi: 10.1002/adma.201805536. Epub 2018 Nov 2.


A Nonpresodiate Sodium-Ion Capacitor with High Performance.

Li S, Chen J, Gong X, Wang J, Lee PS.

Small. 2018 Dec;14(50):e1804035. doi: 10.1002/smll.201804035. Epub 2018 Oct 30.


Skin-touch-actuated textile-based triboelectric nanogenerator with black phosphorus for durable biomechanical energy harvesting.

Xiong J, Cui P, Chen X, Wang J, Parida K, Lin MF, Lee PS.

Nat Commun. 2018 Oct 15;9(1):4280. doi: 10.1038/s41467-018-06759-0.


Neuroimaging Studies of Primary Dysmenorrhea.

Low I, Wei SY, Lee PS, Li WC, Lee LC, Hsieh JC, Chen LF.

Adv Exp Med Biol. 2018;1099:179-199. doi: 10.1007/978-981-13-1756-9_16. Review.


Diphylleia grayi-Inspired Stretchable Hydrochromics with Large Optical Modulation in the Visible-Near-Infrared Region.

Cai G, Wang J, Eh AL, Chen J, Qian K, Xiong J, Thangavel G, Lee PS.

ACS Appl Mater Interfaces. 2018 Oct 31;10(43):37685-37693. doi: 10.1021/acsami.8b12490. Epub 2018 Oct 16.


Hysterectomy with sentinel lymph node biopsy in the setting of pre-operative diagnosis of endometrial intraepithelial neoplasia: A cost-effectiveness analysis.

Lim SL, Moss HA, Secord AA, Lee PS, Havrilesky LJ, Davidson BA.

Gynecol Oncol. 2018 Dec;151(3):506-512. doi: 10.1016/j.ygyno.2018.09.020. Epub 2018 Sep 23.


Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.

Lee PS, Lapointe G, Madera AM, Simmons RL, Xu W, Yifru A, Tjandra M, Karur S, Rico A, Thompson K, Bojkovic J, Xie L, Uehara K, Liu A, Shu W, Bellamacina C, McKenney D, Morris L, Tonn GR, Osborne C, Benton BM, McDowell L, Fu J, Sweeney ZK.

J Med Chem. 2018 Oct 25;61(20):9360-9370. doi: 10.1021/acs.jmedchem.8b01287. Epub 2018 Oct 3.


Correction to Food Bioactives and Their Effects on Obesity-Accelerated Inflammatory Bowel Disease.

Chiou YS, Lee PS, Pan MH.

J Agric Food Chem. 2018 Sep 19;66(37):9868. doi: 10.1021/acs.jafc.8b04593. Epub 2018 Sep 7. No abstract available.


Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial.

Frumovitz M, Plante M, Lee PS, Sandadi S, Lilja JF, Escobar PF, Gien LT, Urbauer DL, Abu-Rustum NR.

Lancet Oncol. 2018 Oct;19(10):1394-1403. doi: 10.1016/S1470-2045(18)30448-0. Epub 2018 Aug 22.


Rational Design of Amphiphilic Peptides and Its Effect on Antifouling Performance.

Gaw SL, Sakala G, Nir S, Saha A, Xu ZJ, Lee PS, Reches M.

Biomacromolecules. 2018 Sep 10;19(9):3620-3627. doi: 10.1021/acs.biomac.8b00587. Epub 2018 Aug 17.


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