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A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis.

Kim YH, Choi J, Yang MJ, Hong SP, Lee CK, Kubota Y, Lim DS, Koh GY.

Nat Commun. 2019 Feb 19;10(1):838. doi: 10.1038/s41467-019-08773-2.


Impact of Preoperative Diagnosis on Clinical Outcomes of Oblique Lateral Interbody Fusion for Lumbar Degenerative Disease in a Single-institution Prospective Cohort.

Chang SY, Nam Y, Lee J, Chang BS, Lee CK, Kim H.

Orthop Surg. 2019 Feb 14. doi: 10.1111/os.12419. [Epub ahead of print]


Pathways to diagnosis of non-small cell lung cancer: a descriptive cohort study.

Purdie S, Creighton N, White KM, Baker D, Ewald D, Lee CK, Lyon A, Man J, Michail D, Miller AA, Tan L, Currow D, Young JM.

NPJ Prim Care Respir Med. 2019 Feb 8;29(1):2. doi: 10.1038/s41533-018-0113-7.


Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation.

Lee CK, Jeong SH, Jang C, Bae H, Kim YH, Park I, Kim SK, Koh GY.

Science. 2019 Feb 8;363(6427):644-649. doi: 10.1126/science.aav0173. Epub 2019 Feb 7.


Comprehensive studies on optimization of cellulase and xylanase production by a local indigenous fungus strain via solid state fermentation using oil palm frond as substrate.

Tai WY, Tan JS, Lim V, Lee CK.

Biotechnol Prog. 2019 Jan 30:e2781. doi: 10.1002/btpr.2781. [Epub ahead of print]


Identification and validation of amino acid-based mild exfoliating agents through a de novo screening method.

Ahn B, Lee SH, Kim JH, Goh A, Park SG, Lee CK, Kang NG.

J Cosmet Dermatol. 2019 Jan 29. doi: 10.1111/jocd.12871. [Epub ahead of print]


Clinical features and recurrent attack in gout patients according to serum urate levels during an acute attack.

Lee JS, Kwon OC, Oh JS, Kim YG, Lee CK, Yoo B, Hong S.

Korean J Intern Med. 2019 Jan 28. doi: 10.3904/kjim.2018.205. [Epub ahead of print]


A new opportunity for innovative inflammatory bowel disease research: the moderate-to-severe ulcerative colitis in Korea (MOSAIK) cohort study.

Lee CK, Lee KM, Park DI, Jung SA, Jeen YT, Park YS, Kim HJ.

Intest Res. 2019 Jan;17(1):1-5. doi: 10.5217/ir.2019.00005. Epub 2019 Jan 25. No abstract available.


Synergistic effects of cAMP-dependent protein kinase A and AMP-activated protein kinase on lipolysis in kinsenoside-treated C3H10T1/2 adipocytes.

Lee YG, Sue YM, Lee CK, Huang HM, He JJ, Wang YS, Juan SH.

Phytomedicine. 2018 Aug 11;55:255-263. doi: 10.1016/j.phymed.2018.06.043. [Epub ahead of print]


Dendrobine targeting JNK stress signaling to sensitize chemotoxicity of cisplatin against non-small cell lung cancer cells in vitro and in vivo.

Song TH, Chen XX, Lee CK, Sze SC, Feng YB, Yang ZJ, Chen HY, Li ST, Zhang LY, Wei G, Shi J, Xu K, Ng TB, Zhu LL, Zhang KY.

Phytomedicine. 2019 Feb;53:18-27. doi: 10.1016/j.phymed.2018.06.018. Epub 2018 Jun 27.


Failure of Pelvic Compensation in Patients with Severe Positive Sagittal Imbalance: Comparison between Static Radiographs and Gait Analysis of Spinopelvic Parameters in Adult Spinal Deformity and Lumbar Stenosis.

Kim HJ, Shen F, Kang KT, Chun HJ, Kim ST, Chang BS, Lee CK, Yeom JS.

Spine (Phila Pa 1976). 2019 Jan 14. doi: 10.1097/BRS.0000000000002985. [Epub ahead of print]


Molecular epidemiology and clinical significance of Corynebacterium striatum isolated from clinical specimens.

Suh JW, Ju Y, Lee CK, Sohn JW, Kim MJ, Yoon YK.

Infect Drug Resist. 2019 Jan 4;12:161-171. doi: 10.2147/IDR.S184518. eCollection 2019.


Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer.

Lee CK, Scott C, Lindeman GJ, Hamilton A, Lieschke E, Gibbs E, Asher R, Badger H, Paterson R, Macnab L, Kwan EM, Francis PA, Boyle F, Friedlander M.

Br J Cancer. 2019 Feb;120(3):279-285. doi: 10.1038/s41416-018-0349-6. Epub 2019 Jan 17.


Preclinical studies of ropivacaine extended-release from a temperature responsive hydrogel for prolonged relief of pain at the surgical wound.

Oh KS, Hwang C, Lee HY, Song JS, Park HJ, Lee CK, Song I, Lim TH.

Int J Pharm. 2019 Mar 10;558:225-230. doi: 10.1016/j.ijpharm.2019.01.011. Epub 2019 Jan 14.


Assessing the impact of respiratory infections and weather conditions on donor attendance and blood inventory in Hong Kong.

Leung K, Lee CK, Lau EHY, Lau CW, Wu JT.

Vox Sang. 2019 Feb;114(2):137-144. doi: 10.1111/vox.12745. Epub 2019 Jan 9.


Optimization of membrane modification using SiO2 for robust anti-fouling performance with calcium-humic acid feed in membrane distillation.

Khan AA, Khan IA, Siyal MI, Lee CK, Kim JO.

Environ Res. 2019 Mar;170:374-382. doi: 10.1016/j.envres.2018.12.036. Epub 2018 Dec 18.


Loss-of-Function Alleles of Heading date 1 (Hd1) Are Associated With Adaptation of Temperate Japonica Rice Plants to the Tropical Region.

Kim SR, Torollo G, Yoon MR, Kwak J, Lee CK, Prahalada GD, Choi IR, Yeo US, Jeong OY, Jena KK, Lee JS.

Front Plant Sci. 2018 Dec 10;9:1827. doi: 10.3389/fpls.2018.01827. eCollection 2018.


Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress: A randomized, double-blind, placebo-controlled clinical trial.

Choi EK, Won YH, Kim SY, Noh SO, Park SH, Jung SJ, Lee CK, Hwang BY, Lee MK, Ha KC, Baek HI, Kim HM, Ko MH, Chae SW.

Phytomedicine. 2019 Jan;52:198-205. doi: 10.1016/j.phymed.2018.05.002. Epub 2018 May 8.


Gastrointestinal: Colon cast with segmental stricture following colonic ischemia.

Park YM, Lee CK, Kim HJ.

J Gastroenterol Hepatol. 2018 Dec 27. doi: 10.1111/jgh.14550. [Epub ahead of print] No abstract available.


Biases in the metabarcoding of plant pathogens using rust fungi as a model system.

Makiola A, Dickie IA, Holdaway RJ, Wood JR, Orwin KH, Lee CK, Glare TR.

Microbiologyopen. 2018 Dec 25:e780. doi: 10.1002/mbo3.780. [Epub ahead of print]


Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea.

Song JJ, Song YW, Bae SC, Cha HS, Choe JY, Choi SJ, Kim HA, Kim J, Kim SS, Lee CK, Lee J, Lee SH, Lee SS, Lee SK, Lee SW, Park SH, Park W, Shim SC, Suh CH, Yoo B, Yoo DH, Yoo WH.

J Korean Med Sci. 2018 Dec 18;33(52):e346. doi: 10.3346/jkms.2018.33.e346. eCollection 2018 Dec 24.


Stearoyl-coenzyme A desaturase 1 is required for lipid droplet formation in pig embryo.

Lee DK, Choi KH, Hwang JY, Oh JN, Kim SH, Lee CK.

Reproduction. 2018 Dec 1. pii: REP-18-0556.R1. doi: 10.1530/REP-18-0556. [Epub ahead of print]


Integrative functional genomic analysis of human brain development and neuropsychiatric risks.

Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw CA, Pardiñas AF; BrainSpan Consortium; PsychENCODE Consortium; PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Reimers MA, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N.

Science. 2018 Dec 14;362(6420). pii: eaat7615. doi: 10.1126/science.aat7615.


Growth signaling and longevity in mouse models.

Kim SS, Lee CK.

BMB Rep. 2019 Jan;52(1):70-85.


Melanogenesis Inhibitors from the Rhizoma of Ligusticum Sinense in B16-F10 Melanoma Cells In Vitro and Zebrafish In Vivo.

Cheng MC, Lee TH, Chu YT, Syu LL, Hsu SJ, Cheng CH, Wu J, Lee CK.

Int J Mol Sci. 2018 Dec 11;19(12). pii: E3994. doi: 10.3390/ijms19123994.


Pre-clinical evaluation of a P. berghei-based whole-sporozoite malaria vaccine candidate.

Mendes AM, Reuling IJ, Andrade CM, Otto TD, Machado M, Teixeira F, Pissarra J, Gonçalves-Rosa N, Bonaparte D, Sinfrónio J, Sanders M, Janse CJ, Khan SM, Newbold CI, Berriman M, Lee CK, Wu Y, Ockenhouse CF, Sauerwein RW, Prudêncio M.

NPJ Vaccines. 2018 Nov 27;3:54. doi: 10.1038/s41541-018-0091-3. eCollection 2018.


Controlled attenuation parameter: A measure of hepatic steatosis in patients with cystic fibrosis.

Bader RM, Jonas MM, Mitchell PD, Wiggins S, Lee CK.

J Cyst Fibros. 2018 Nov 30. pii: S1569-1993(18)30932-9. doi: 10.1016/j.jcf.2018.11.004. [Epub ahead of print]


Low handgrip strength is closely associated with chronic low back pain among women aged 50 years or older: A cross-sectional study using a national health survey.

Park SM, Kim GU, Kim HJ, Kim H, Chang BS, Lee CK, Yeom JS.

PLoS One. 2018 Nov 26;13(11):e0207759. doi: 10.1371/journal.pone.0207759. eCollection 2018.


Surface Characterizations of Railway Electrical Wires Coated with Anti-Icing Mixtures of Ethylene Glycol or Glycerol with Tap Water.

Kim YK, Bui VKH, Lee JY, Lee CK, Lee HU, Lee YC.

J Nanosci Nanotechnol. 2019 Mar 1;19(3):1269-1275. doi: 10.1166/jnn.2019.16162.


The impact of ethnicity on efficacy and toxicity of cyclin D kinase 4/6 inhibitors in advanced breast cancer: a meta-analysis.

Lee KWC, Lord S, Finn RS, Lim E, Martin A, Loi S, Lynch J, Friedlander M, Lee CK.

Breast Cancer Res Treat. 2018 Nov 21. doi: 10.1007/s10549-018-5054-x. [Epub ahead of print]


Stochastic and Deterministic Effects of a Moisture Gradient on Soil Microbial Communities in the McMurdo Dry Valleys of Antarctica.

Lee KC, Caruso T, Archer SDJ, Gillman LN, Lau MCY, Cary SC, Lee CK, Pointing SB.

Front Microbiol. 2018 Nov 1;9:2619. doi: 10.3389/fmicb.2018.02619. eCollection 2018.


Walking more than 90 minutes/week was associated with a lower risk of self-reported low back pain in persons over 50 years of age: a cross-sectional study using the Korean National Health and Nutrition Examination Surveys.

Park SM, Kim GU, Kim HJ, Kim H, Chang BS, Lee CK, Yeom JS.

Spine J. 2018 Nov 15. pii: S1529-9430(18)31226-9. doi: 10.1016/j.spinee.2018.11.007. [Epub ahead of print]


Significance of 1 kHz Pure-tone Threshold in Acute Low-frequency Sensorineural Hearing Loss.

Lee CK, Lee JB, Park KH, Lee HY, Choi MJ, Ban W, Choi SJ.

Otol Neurotol. 2018 Dec;39(10):e950-e955. doi: 10.1097/MAO.0000000000002023.


Hepatic Safety of Febuxostat Compared with Allopurinol in Gout Patients with Fatty Liver Disease.

Lee JS, Won J, Kwon OC, Lee SS, Oh JS, Kim YG, Lee CK, Yoo B, Hong S.

J Rheumatol. 2018 Nov 15. pii: jrheum.180761. doi: 10.3899/jrheum.180761. [Epub ahead of print]


17β-Estradiol protects mesenchymal stem cells against high glucose-induced mitochondrial oxidants production via Nrf2/Sirt3/MnSOD signaling.

Oh JY, Choi GE, Lee HJ, Jung YH, Chae CW, Kim JS, Lee CK, Han HJ.

Free Radic Biol Med. 2019 Jan;130:328-342. doi: 10.1016/j.freeradbiomed.2018.11.003. Epub 2018 Nov 6.


Learning Curve for Lumbar Decompressive Laminectomy in Biportal Endoscopic Spinal Surgery Using the Cumulative Summation Test for Learning Curve.

Park SM, Kim HJ, Kim GU, Choi MH, Chang BS, Lee CK, Yeom JS.

World Neurosurg. 2019 Feb;122:e1007-e1013. doi: 10.1016/j.wneu.2018.10.197. Epub 2018 Nov 4.


Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial.

van der Heijde D, Cheng-Chung Wei J, Dougados M, Mease P, Deodhar A, Maksymowych WP, Van den Bosch F, Sieper J, Tomita T, Landewé R, Zhao F, Krishnan E, Adams DH, Pangallo B, Carlier H; COAST-V study group.

Lancet. 2018 Dec 8;392(10163):2441-2451. doi: 10.1016/S0140-6736(18)31946-9. Epub 2018 Oct 22.


Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.

Tsai YF, Yang DJ, Ngo TH, Shih CH, Wu YF, Lee CK, Phraekanjanavichid V, Yen SF, Kao SH, Lee HM, Huang VS, Shieh JC, Lin YF.

ACS Chem Neurosci. 2018 Oct 26. doi: 10.1021/acschemneuro.8b00406. [Epub ahead of print]


Efficacy and Safety of Ixekizumab in the Treatment of Radiographic Axial Spondyloarthritis: 16 Week Results of a Phase 3 Randomized, Double-Blind, Placebo Controlled Trial in Patients with Prior Inadequate Response or Intolerance to Tumor Necrosis Factor Inhibitors.

Deodhar A, Poddubnyy D, Pacheco-Tena C, Salvarani C, Lespessailles E, Rahman P, Järvinen P, Sanchez-Burson J, Gaffney K, Lee EB, Krishnan E, Santisteban S, Li X, Zhao F, Carlier H, Reveille JD; COAST-W study group.

Arthritis Rheumatol. 2018 Oct 20. doi: 10.1002/art.40753. [Epub ahead of print]


Near Infrared Fluorophore-Tagged Chloroquine in Plasmodium falciparum Diagnostic Imaging.

Chan LY, Teo JDW, Tan KS, Sou K, Kwan WL, Lee CK.

Molecules. 2018 Oct 14;23(10). pii: E2635. doi: 10.3390/molecules23102635.


Volatile profiles and involvement step of moisture in bulk oils during oxidation by action of deuterium oxide (D2O).

Lee CK, Yi BR, Kim SH, Choi HS, Kim MJ, Lee JH.

Food Sci Biotechnol. 2018 Jun 21;27(5):1327-1332. doi: 10.1007/s10068-018-0380-7. eCollection 2018 Oct.


Dose-Response Relationship Between Diltiazem and Tacrolimus and Its Safety in Renal Transplant Recipients.

Choong CL, Wong HS, Lee FY, Lee CK, Kho JV, Lai YX, Vikneswaran T.

Transplant Proc. 2018 Oct;50(8):2515-2520. doi: 10.1016/j.transproceed.2018.04.024. Epub 2018 Apr 12.


Streptococcus gallolyticus Bacteremia and Colorectal Carcinoma.

Wong HK, Ho PL, Lee CK.

Gastroenterology. 2019 Jan;156(1):291-292. doi: 10.1053/j.gastro.2018.07.059. Epub 2018 Oct 10. No abstract available.


Combined hepatocellular carcinoma and high grade neuroendocrine carcinoma with EWSR1 gene rearrangement.

Chuah KL, Pang B, Lim D, Lee CK, Chau CY.

Pathology. 2018 Dec;50(7):779-782. doi: 10.1016/j.pathol.2018.07.005. Epub 2018 Oct 9. No abstract available.


A long wait: barriers to discharge for long length of stay patients.

Zhao EJ, Yeluru A, Manjunath L, Zhong LR, Hsu HT, Lee CK, Wong AC, Abramian M, Manella H, Svec D, Shieh L.

Postgrad Med J. 2018 Oct;94(1116):546-550. doi: 10.1136/postgradmedj-2018-135815. Epub 2018 Oct 9.


Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction.

Lee SJ, Lee CK, Kang S, Park I, Kim YH, Kim SK, Hong SP, Bae H, He Y, Kubota Y, Koh GY.

J Clin Invest. 2018 Nov 1;128(11):5018-5033. doi: 10.1172/JCI99659. Epub 2018 Oct 8.


Attempting to Convert Primed Porcine Embryonic Stem Cells into a Naive State Through the Overexpression of Reprogramming Factors.

Park TY, Choi KH, Lee DK, Oh JN, Kim SH, Lee CK.

Cell Reprogram. 2018 Oct;20(5):289-300. doi: 10.1089/cell.2017.0071.


A multicomponent frailty intervention for socioeconomically vulnerable older adults: a designed-delay study.

Jang IY, Jung HW, Park H, Lee CK, Yu SS, Lee YS, Lee E, Glynn RJ, Kim DH.

Clin Interv Aging. 2018 Sep 19;13:1799-1814. doi: 10.2147/CIA.S177018. eCollection 2018.

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