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Redo tricuspid valve operation in patients with 1st-generation mitral prostheses.

Chow SC, Lee AP, Ho AM, Chan HH, Underwood MJ, Wan S.

Asian Cardiovasc Thorac Ann. 2018 Aug 12:218492318795545. doi: 10.1177/0218492318795545. [Epub ahead of print]


A Call for Standardization in Left Atrial Appendage Occlusion.

So CY, Cheung GS, Chan AK, Lee AP, Lam YY.

J Am Coll Cardiol. 2018 Jul 24;72(4):472-473. doi: 10.1016/j.jacc.2018.04.075. No abstract available.


Junior medical student performed focused cardiac ultrasound after brief training to detect significant valvular heart disease.

Yan BP, Fok JC, Wong TH, Tse G, Lee APW, Yang XS, Sun JP.

Int J Cardiol Heart Vasc. 2018 May 2;19:41-45. doi: 10.1016/j.ijcha.2018.03.007. eCollection 2018 Jun.


A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function.

Wang X, Zhao D, Phan DTT, Liu J, Chen X, Yang B, Hughes CCW, Zhang W, Lee AP.

Lab Chip. 2018 Jul 24;18(15):2167-2177. doi: 10.1039/c8lc00236c.


Telemonitoring and hemodynamic monitoring to reduce hospitalization rates in heart failure: a systematic review and meta-analysis of randomized controlled trials and real-world studies.

Tse G, Chan C, Gong M, Meng L, Zhang J, Su XL, Ali-Hasan-Al-Saegh S, Sawant AC, Bazoukis G, Xia YL, Zhao JC, Lee APW, Roever L, Wong MC, Baranchuk A, Liu T; International Health Informatics Study (IHIS) Network.

J Geriatr Cardiol. 2018 Apr;15(4):298-309. doi: 10.11909/j.issn.1671-5411.2018.04.008.


Effect of Treat-to-target Strategies Aiming at Remission of Arterial Stiffness in Early Rheumatoid Arthritis: A Randomized Controlled Study.

Tam LH, Shang Q, Li EK, Wong PC, Kwok KY, Kun EW, Yim IC, Lee VK, Yip RM, Pang SH, Lao VW, Mak QW, Cheng IT, Lau XS, Li TK, Zhu TY, Lee AP, Tam LS.

J Rheumatol. 2018 May 15. pii: jrheum.171128. doi: 10.3899/jrheum.171128. [Epub ahead of print]


Cell-sized lipid vesicles for cell-cell synaptic therapies.

Vallejo D, Lee SH, Lee D, Zhang C, Rapier C, Chessler SD, Lee AP.

Technology (Singap World Sci). 2017 Dec;5(4):201-213. doi: 10.1142/S233954781750011X. Epub 2018 Jan 24.


Heart Failure and Frailty in the Community-Living Elderly Population: What the UFO Study Will Tell Us.

Fung E, Hui E, Yang X, Lui LT, Cheng KF, Li Q, Fan Y, Sahota DS, Ma BHM, Lee JSW, Lee APW, Woo J.

Front Physiol. 2018 Apr 24;9:347. doi: 10.3389/fphys.2018.00347. eCollection 2018.


Genotype-guided warfarin dosing vs. conventional dosing strategies: a systematic review and meta-analysis of randomized controlled trials.

Tse G, Gong M, Li G, Wong SH, Wu WKK, Wong WT, Roever L, Lee APW, Lip GYH, Wong MCS, Liu T; International Health Informatics Study (IHIS) Network.

Br J Clin Pharmacol. 2018 Apr 28. doi: 10.1111/bcp.13621. [Epub ahead of print]


Transcatheter tricuspid valve edge-to-edge repair for severe tricuspid regurgitation in a Chinese patient.

Cheung GSH, Kam KKH, Lam YY, Lee APW.

Heart Asia. 2018 Apr 16;10(1):e010997. doi: 10.1136/heartasia-2017-010997. eCollection 2018. No abstract available.


Experimental validation of robot-assisted cardiovascular catheterization: model-based versus model-free control.

Wang X, Lee KH, Fu DKC, Dong Z, Wang K, Fang G, Lee SL, Lee APW, Kwok KW.

Int J Comput Assist Radiol Surg. 2018 Jun;13(6):797-804. doi: 10.1007/s11548-018-1757-z. Epub 2018 Apr 2.


Excessive interferon-α signaling in autoimmunity alters glycosphingolipid processing in B cells.

Tan AH, Sanny A, Ng SW, Ho YS, Basri N, Lee AP, Lam KP.

J Autoimmun. 2018 May;89:53-62. doi: 10.1016/j.jaut.2017.11.004. Epub 2017 Nov 27.


Underestimation of Risk of Carotid Subclinical Atherosclerosis by Cardiovascular Risk Scores in Patients with Psoriatic Arthritis.

Shen J, Lam SH, Shang Q, Wong CK, Li EK, Wong P, Kun EW, Cheng IT, Li M, Li TK, Zhu TY, Lee JJ, Chang M, Lee AP, Tam LS.

J Rheumatol. 2018 Feb;45(2):218-226. doi: 10.3899/jrheum.170025. Epub 2017 Nov 15.


High-efficiency single cell encapsulation and size selective capture of cells in picoliter droplets based on hydrodynamic micro-vortices.

Kamalakshakurup G, Lee AP.

Lab Chip. 2017 Dec 5;17(24):4324-4333. doi: 10.1039/c7lc00972k.


Does Kidney Donor Risk Index implementation lead to the transplantation of more and higher-quality donor kidneys?

Philipse E, Lee APK, Bracke B, Hartman V, Chapelle T, Roeyen G, de Greef K, Ysebaert DK, van Beeumen G, Couttenye MM, Van Craenenbroeck AH, Hellemans R, Bosmans JL, Abramowicz D.

Nephrol Dial Transplant. 2017 Nov 1;32(11):1934-1938. doi: 10.1093/ndt/gfx257.


Acute hantavirus infection presenting as haemolytic-uraemic syndrome (HUS): the importance of early clinical diagnosis.

Clement J, Lee APK, Verpooten GA, Laenen L, Vergote V, De Samblanx H, Berneman ZN, Van Ranst M, Maes P.

Eur J Clin Microbiol Infect Dis. 2018 Jan;37(1):135-140. doi: 10.1007/s10096-017-3113-6. Epub 2017 Oct 6.


Automated left heart chamber volumetric assessment using three-dimensional echocardiography in Chinese adolescents.

Luo XX, Fang F, So HK, Liu C, Yam MC, Lee AP.

Echo Res Pract. 2017 Dec;4(4):53-61. doi: 10.1530/ERP-17-0028. Epub 2017 Sep 1.


Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study.

Lee AP, Mulligan K, Schambelan M, Murphy EJ, Weiss EJ.

F1000Res. 2017 May 3;6:614. doi: 10.12688/f1000research.11359.1. eCollection 2017.


Pharmacokinetics of MHAA4549A, an Anti-Influenza A Monoclonal Antibody, in Healthy Subjects Challenged with Influenza A Virus in a Phase IIa Randomized Trial.

Deng R, Lee AP, Maia M, Lim JJ, Burgess T, Horn P, Derby MA, Newton E, Tavel JA, Hanley WD.

Clin Pharmacokinet. 2018 Mar;57(3):367-377. doi: 10.1007/s40262-017-0564-y.


3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.

Wang X, Phan DTT, George SC, Hughes CCW, Lee AP.

Methods Mol Biol. 2017;1612:325-344. doi: 10.1007/978-1-4939-7021-6_24.


A high throughput microfluidic platform for size-selective enrichment of cell populations in tissue and blood samples.

Nivedita N, Garg N, Lee AP, Papautsky I.

Analyst. 2017 Jul 10;142(14):2558-2569. doi: 10.1039/c7an00290d.


Functional Implication of Mitral Annular Disjunction in Mitral Valve Prolapse: A Quantitative Dynamic 3D Echocardiographic Study.

Lee AP, Jin CN, Fan Y, Wong RHL, Underwood MJ, Wan S.

JACC Cardiovasc Imaging. 2017 Dec;10(12):1424-1433. doi: 10.1016/j.jcmg.2016.11.022. Epub 2017 May 17.


Using Multimaterial 3-Dimensional Printing for Personalized Planning of Complex Structural Heart Disease Intervention.

So KC, Fan Y, Sze L, Kwok KW, Chan AK, Cheung GS, Lee AP.

JACC Cardiovasc Interv. 2017 Jun 12;10(11):e97-e98. doi: 10.1016/j.jcin.2017.02.045. Epub 2017 May 17. No abstract available.


Transcatheter aortic valve implantation: the transaortic approach.

Chow SC, Cheung GS, Lee AP, Wu EB, Ho JY, Kwok MW, Yu PS, Wan IY, Underwood MJ, Wong RH.

Asian Cardiovasc Thorac Ann. 2017 Jun;25(5):357-363. doi: 10.1177/0218492317702027. Epub 2017 May 17.


Pharmacodynamics of remifentanil. Induced intracranial spike activity in mesial temporal lobe epilepsy.

Kjaer TW, Hogenhaven H, Lee AP, Madsen FF, Jespersen B, Brennum J, Derm L, Moltke FB.

Epilepsy Res. 2017 Jul;133:41-45. doi: 10.1016/j.eplepsyres.2017.03.008. Epub 2017 Mar 31.


In situ mRNA isolation from a microfluidic single-cell array using an external AFM nanoprobe.

Li X, Tao Y, Lee DH, Wickramasinghe HK, Lee AP.

Lab Chip. 2017 May 2;17(9):1635-1644. doi: 10.1039/c7lc00133a.


In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA).

Billones JB, Carrillo MC, Organo VG, Sy JB, Clavio NA, Macalino SJ, Emnacen IA, Lee AP, Ko PK, Concepcion GP.

Drug Des Devel Ther. 2017 Mar 2;11:563-574. doi: 10.2147/DDDT.S119930. eCollection 2017.


A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.

Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW.

Lab Chip. 2017 Jan 31;17(3):511-520. doi: 10.1039/c6lc01422d.


The influence of ultra-pasteurization by indirect heating versus direct steam injection on skim and 2% fat milks.

Lee AP, Barbano DM, Drake MA.

J Dairy Sci. 2017 Mar;100(3):1688-1701. doi: 10.3168/jds.2016-11899. Epub 2017 Jan 11.


Increased prevalence of coronary plaque in patients with psoriatic arthritis without prior diagnosis of coronary artery disease.

Shen J, Wong KT, Cheng IT, Shang Q, Li EK, Wong P, Kun EW, Law MY, Yip R, Yim I, Ying S, Li M, Li TK, Wong CK, Zhu TY, Lee JJ, Chang M, Lee AP, Tam LS.

Ann Rheum Dis. 2017 Jul;76(7):1237-1244. doi: 10.1136/annrheumdis-2016-210390. Epub 2017 Jan 4.


The seahorse genome and the evolution of its specialized morphology.

Lin Q, Fan S, Zhang Y, Xu M, Zhang H, Yang Y, Lee AP, Woltering JM, Ravi V, Gunter HM, Luo W, Gao Z, Lim ZW, Qin G, Schneider RF, Wang X, Xiong P, Li G, Wang K, Min J, Zhang C, Qiu Y, Bai J, He W, Bian C, Zhang X, Shan D, Qu H, Sun Y, Gao Q, Huang L, Shi Q, Meyer A, Venkatesh B.

Nature. 2016 Dec 14;540(7633):395-399. doi: 10.1038/nature20595.


Short communication: The effect of raw milk cooling on sensory perception and shelf life of high-temperature, short-time (HTST)-pasteurized skim milk.

Lee AP, Barbano DM, Drake MA.

J Dairy Sci. 2016 Dec;99(12):9659-9667. doi: 10.3168/jds.2016-11771. Epub 2016 Oct 13.


The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate.

Pan H, Yu H, Ravi V, Li C, Lee AP, Lian MM, Tay BH, Brenner S, Wang J, Yang H, Zhang G, Venkatesh B.

Gigascience. 2016 Sep 9;5(1):36. doi: 10.1186/s13742-016-0144-3.


3D microtumors in vitro supported by perfused vascular networks.

Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC.

Sci Rep. 2016 Aug 23;6:31589. doi: 10.1038/srep31589.


Contrast-Enhanced Transthoracic Aortic Ultrasonography for Endoleak Detection After Thoracic Endovascular Aortic Repair.

Lee AP, Wong RH, Underwood MJ, Yu SC.

Ann Thorac Surg. 2016 Sep;102(3):e261. doi: 10.1016/j.athoracsur.2016.03.056. No abstract available.


Using Anatomic Intelligence to Localize Mitral Valve Prolapse on Three-Dimensional Echocardiography.

Jin CN, Salgo IS, Schneider RJ, Kam KK, Chi WK, So CY, Tang Z, Wan S, Wong R, Underwood M, Lee AP.

J Am Soc Echocardiogr. 2016 Oct;29(10):938-945. doi: 10.1016/j.echo.2016.07.002. Epub 2016 Aug 18.


Impact of Intramyocardial Hemorrhage and Microvascular Obstruction on Cardiac Mechanics in Reperfusion Injury: A Speckle-Tracking Echocardiographic Study.

Zhao H, Lee AP, Li Z, Qiao Z, Fan Y, An D, Xu J, Pu J, Shen X, Ge H, He B.

J Am Soc Echocardiogr. 2016 Oct;29(10):973-982. doi: 10.1016/j.echo.2016.06.011. Epub 2016 Aug 11.


Mitral valve repair using a semirigid ring: patient selection and early outcomes.

Wan S, Lee AP, Attaran S, Yu PS, Au SS, Kwok MW, Lau RW, Wong RH, Wan IY, Ng SK, Underwood MJ.

Asian Cardiovasc Thorac Ann. 2016 Sep;24(7):647-52. doi: 10.1177/0218492316659970. Epub 2016 Jul 21.


How does an integrated primary care approach for patients in deprived neighbourhoods impact utilization patterns? An explorative study.

Kringos DS, van den Broeke JR, van der Lee AP, Plochg T, Stronks K.

BMC Public Health. 2016 Jul 11;16:545. doi: 10.1186/s12889-016-3246-z.


Electrophysiological Mechanisms of Gastrointestinal Arrhythmogenesis: Lessons from the Heart.

Tse G, Lai ET, Lee AP, Yan BP, Wong SH.

Front Physiol. 2016 Jun 14;7:230. doi: 10.3389/fphys.2016.00230. eCollection 2016. Review.


Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T, Chalopin D, Fan S, Wcisel D, Cañestro C, Sydes J, Beaudry FE, Sun Y, Hertel J, Beam MJ, Fasold M, Ishiyama M, Johnson J, Kehr S, Lara M, Letaw JH, Litman GW, Litman RT, Mikami M, Ota T, Saha NR, Williams L, Stadler PF, Wang H, Taylor JS, Fontenot Q, Ferrara A, Searle SM, Aken B, Yandell M, Schneider I, Yoder JA, Volff JN, Meyer A, Amemiya CT, Venkatesh B, Holland PW, Guiguen Y, Bobe J, Shubin NH, Di Palma F, Alfo Ldi J, Lindblad-Toh K, Postlethwait JH.

Nat Genet. 2016 May 27;48(6):700. doi: 10.1038/ng0616-700c. No abstract available.


[Health care usage by minimum income citizens in Amsterdam; a cross-sectional study into claims within the Dutch basic health insurance scheme].

Dijkshoorn H, Hazeleger FG, de Jong IM, van der Lee AP, Kunst AE.

Ned Tijdschr Geneeskd. 2016;160:A9816. Dutch.


Prevalence of atrial septal pouch and risk of ischemic stroke.

Sun JP, Meng F, Yang XS, Lee AP, Chen M, Zhang B, Yu CM.

Int J Cardiol. 2016 Jul 1;214:37-40. doi: 10.1016/j.ijcard.2016.03.119. Epub 2016 Mar 24.


The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

Braasch I, Gehrke AR, Smith JJ, Kawasaki K, Manousaki T, Pasquier J, Amores A, Desvignes T, Batzel P, Catchen J, Berlin AM, Campbell MS, Barrell D, Martin KJ, Mulley JF, Ravi V, Lee AP, Nakamura T, Chalopin D, Fan S, Wcisel D, Cañestro C, Sydes J, Beaudry FE, Sun Y, Hertel J, Beam MJ, Fasold M, Ishiyama M, Johnson J, Kehr S, Lara M, Letaw JH, Litman GW, Litman RT, Mikami M, Ota T, Saha NR, Williams L, Stadler PF, Wang H, Taylor JS, Fontenot Q, Ferrara A, Searle SM, Aken B, Yandell M, Schneider I, Yoder JA, Volff JN, Meyer A, Amemiya CT, Venkatesh B, Holland PW, Guiguen Y, Bobe J, Shubin NH, Di Palma F, Alföldi J, Lindblad-Toh K, Postlethwait JH.

Nat Genet. 2016 Apr;48(4):427-37. doi: 10.1038/ng.3526. Epub 2016 Mar 7.


Three-Dimensional Printing for Planning Occlusion Procedure for a Double-Lobed Left Atrial Appendage.

Fan Y, Kwok KW, Zhang Y, Cheung GS, Chan AK, Lee AP.

Circ Cardiovasc Interv. 2016 Mar;9(3):e003561. doi: 10.1161/CIRCINTERVENTIONS.116.003561. No abstract available.


An on-chip microfluidic pressure regulator that facilitates reproducible loading of cells and hydrogels into microphysiological system platforms.

Wang X, Phan DTT, Zhao D, George SC, Hughes CCW, Lee AP.

Lab Chip. 2016 Mar 7;16(5):868-876. doi: 10.1039/c5lc01563d.


Evaluation of quantum dot immunofluorescence and a digital CMOS imaging system as an alternative to conventional organic fluorescence dyes and laser scanning for quantifying protein microarrays.

Jain A, Taghavian O, Vallejo D, Dotsey E, Schwartz D, Bell FG, Greef C, Davies DH, Grudzien J, Lee AP, Felgner PL, Liang L.

Proteomics. 2016 Apr;16(8):1271-9. doi: 10.1002/pmic.201500375. Epub 2016 Mar 29.


Post-Formation Shrinkage and Stabilization of Microfluidic Bubbles in Lipid Solution.

Shih R, Lee AP.

Langmuir. 2016 Mar 1;32(8):1939-46. doi: 10.1021/acs.langmuir.5b03948. Epub 2016 Feb 18.


The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans.

Coffill CR, Lee AP, Siau JW, Chee SM, Joseph TL, Tan YS, Madhumalar A, Tay BH, Brenner S, Verma CS, Ghadessy FJ, Venkatesh B, Lane DP.

Genes Dev. 2016 Feb 1;30(3):281-92. doi: 10.1101/gad.274118.115. Epub 2016 Jan 21.

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