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Items: 1 to 50 of 878

1.

Sustained Low-dose Dexamethasone Delivery Via a PLGA Microsphere-embedded Agarose Implant for Enhanced Osteochondral Repair.

Stefani RM, Lee AJ, Tan AR, Halder SS, Hu Y, Guo XE, Stoker AM, Ateshian GA, Marra KG, Cook JL, Hung CT.

Acta Biomater. 2019 Dec 2. pii: S1742-7061(19)30802-5. doi: 10.1016/j.actbio.2019.11.052. [Epub ahead of print]

PMID:
31805408
2.

Readmissions After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: a US HIPEC Collaborative Study.

Lee TC, Wima K, Sussman JJ, Ahmad SA, Cloyd JM, Ahmed A, Fournier K, Lee AJ, Dineen S, Powers B, Veerapong J, Baumgartner JM, Clarke C, Mogal H, Zaidi MY, Maithel SK, Leiting J, Grotz T, Lambert L, Hendrix RJ, Abbott DE, Pokrzywa C, Blakely AM, Lee B, Johnston FM, Greer J, Patel SH.

J Gastrointest Surg. 2019 Nov 19. doi: 10.1007/s11605-019-04463-y. [Epub ahead of print]

PMID:
31745888
3.

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.

Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkıran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidović RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijević V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton JB, Larsen DJ, Omdahl AR, McGuffin LJ, Brackenridge DA, Babbitt PC, Yunes JM, Fontana P, Zhang F, Zhu S, You R, Zhang Z, Dai S, Yao S, Tian W, Cao R, Chandler C, Amezola M, Johnson D, Chang JM, Liao WH, Liu YW, Pascarelli S, Frank Y, Hoehndorf R, Kulmanov M, Boudellioua I, Politano G, Di Carlo S, Benso A, Hakala K, Ginter F, Mehryary F, Kaewphan S, Björne J, Moen H, Tolvanen MEE, Salakoski T, Kihara D, Jain A, Šmuc T, Altenhoff A, Ben-Hur A, Rost B, Brenner SE, Orengo CA, Jeffery CJ, Bosco G, Hogan DA, Martin MJ, O'Donovan C, Mooney SD, Greene CS, Radivojac P, Friedberg I.

Genome Biol. 2019 Nov 19;20(1):244. doi: 10.1186/s13059-019-1835-8.

4.

Atherosclerotic cardiovascular disease in women with endometriosis: a systematic review of risk factors and prospects for early surveillance.

Tan J, Taskin O, Iews M, Lee AJ, Kan A, Rowe T, Bedaiwy MA.

Reprod Biomed Online. 2019 Jun 8. pii: S1472-6483(19)30585-1. doi: 10.1016/j.rbmo.2019.05.021. [Epub ahead of print] Review.

PMID:
31735549
5.

Healthcare professionals must communicate with patients and relatives. They must enable informed, realistic and appropriate decisions in end-of-life pharmacotherapy.

Lee AJ.

Evid Based Nurs. 2019 Nov 12. pii: ebnurs-2019-103179. doi: 10.1136/ebnurs-2019-103179. [Epub ahead of print] No abstract available.

PMID:
31719127
6.

The role of 5α-reductase inhibitors in gastro-oesophageal cancer risk: A nested case-control study.

Busby J, Karasneh R, Murchie P, McMenamin Ú, Gadalla SM, Camargo MC, Iversen L, Lee AJ, Spence AD, Cardwell CR.

Pharmacoepidemiol Drug Saf. 2019 Nov 12. doi: 10.1002/pds.4909. [Epub ahead of print]

PMID:
31713940
7.

VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers.

Kim CG, Jang M, Kim Y, Leem G, Kim KH, Lee H, Kim TS, Choi SJ, Kim HD, Han JW, Kwon M, Kim JH, Lee AJ, Nam SK, Bae SJ, Lee SB, Shin SJ, Park SH, Ahn JB, Jung I, Lee KY, Park SH, Kim H, Min BS, Shin EC.

Sci Immunol. 2019 Nov 8;4(41). pii: eaay0555. doi: 10.1126/sciimmunol.aay0555.

PMID:
31704735
8.

Predictors of Anastomotic Failure After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Does Technique Matter?

Wiseman JT, Kimbrough C, Beal EW, Zaidi MY, Staley CA, Grotz T, Leiting J, Fournier K, Lee AJ, Dineen S, Powers B, Veerapong J, Baumgartner JM, Clarke C, Patel SH, Dhar V, Hendrix RJ, Lambert L, Abbott DE, Pokrzywa C, Raoof M, Lee B, Fackche N, Greer J, Pawlik TM, Abdel-Misih S, Cloyd JM.

Ann Surg Oncol. 2019 Oct 28. doi: 10.1245/s10434-019-07964-x. [Epub ahead of print]

PMID:
31659645
9.

Contribution of shape and surface reflectance information to kinship detection in 3D face images.

Fasolt V, Holzleitner IJ, Lee AJ, O'Shea KJ, DeBruine LM.

J Vis. 2019 Oct 1;19(12):9. doi: 10.1167/19.12.9.

PMID:
31621819
10.

IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.

Karimi Y, Giles EC, Vahedi F, Chew MV, Nham T, Loukov D, Lee AJ, Bowdish DM, Ashkar AA.

Innate Immun. 2019 Oct 15:1753425919878839. doi: 10.1177/1753425919878839. [Epub ahead of print] No abstract available.

PMID:
31615311
11.

Preoperative Risk Score for Predicting Incomplete Cytoreduction: A 12-Institution Study from the US HIPEC Collaborative.

Zaidi MY, Lee RM, Gamboa AC, Speegle S, Cloyd JM, Kimbrough C, Grotz T, Leiting J, Fournier K, Lee AJ, Dineen S, Dessureault S, Kelly KJ, Kotha NV, Clarke C, Gamblin TC, Patel SH, Lee TC, Hendrix RJ, Lambert L, Ronnekleiv-Kelly S, Pokrzywa C, Blakely AM, Lee B, Johnston FM, Fackche N, Russell MC, Maithel SK, Staley CA 3rd.

Ann Surg Oncol. 2019 Oct 10. doi: 10.1245/s10434-019-07626-y. [Epub ahead of print]

PMID:
31602579
12.

Mitochondrial heat shock protein-guided photodynamic therapy.

Thomas AP, Lee AJ, Palanikumar L, Jana B, Kim K, Kim S, Ok H, Seol J, Kim D, Kang BH, Ryu JH.

Chem Commun (Camb). 2019 Oct 17;55(84):12631-12634. doi: 10.1039/c9cc06411g.

PMID:
31580341
13.

Trends in the indications for and short-term outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.

Beal EW, Ahmed A, Grotz T, Leiting J, Fournier KF, Lee AJ, Dineen S, Dessureault S, Baumgartner JM, Veerapong J, Clarke C, Strong E, Maithel SK, Zaidi MY, Patel S, Dhar V, Hendrix R, Lambert L, Johnston F, Fackche N, Raoof M, LaRocca C, Ronnekleiv-Kelly S, Pokrzywa C, Pawlik TM, Abdel-Misih S, Cloyd JM.

Am J Surg. 2019 Sep 19. pii: S0002-9610(19)30848-7. doi: 10.1016/j.amjsurg.2019.09.017. [Epub ahead of print]

PMID:
31558307
14.

Comparing theory-driven and data-driven attractiveness models using images of real women's faces.

Holzleitner IJ, Lee AJ, Hahn AC, Kandrik M, Bovet J, Renoult JP, Simmons D, Garrod O, DeBruine LM, Jones BC.

J Exp Psychol Hum Percept Perform. 2019 Dec;45(12):1589-1595. doi: 10.1037/xhp0000685. Epub 2019 Sep 26.

PMID:
31556686
15.

Versatile biomanufacturing through stimulus-responsive cell-material feedback.

Dai Z, Lee AJ, Roberts S, Sysoeva TA, Huang S, Dzuricky M, Yang X, Zhang X, Liu Z, Chilkoti A, You L.

Nat Chem Biol. 2019 Oct;15(10):1017-1024. doi: 10.1038/s41589-019-0357-8. Epub 2019 Sep 16.

PMID:
31527836
16.

A compendium of promoter-centered long-range chromatin interactions in the human genome.

Jung I, Schmitt A, Diao Y, Lee AJ, Liu T, Yang D, Tan C, Eom J, Chan M, Chee S, Chiang Z, Kim C, Masliah E, Barr CL, Li B, Kuan S, Kim D, Ren B.

Nat Genet. 2019 Oct;51(10):1442-1449. doi: 10.1038/s41588-019-0494-8. Epub 2019 Sep 9.

PMID:
31501517
17.

A Good Practice-Compliant Clinical Trial Imaging Management System for Multicenter Clinical Trials: Development and Validation Study.

Shin Y, Kim KW, Lee AJ, Sung YS, Ahn S, Koo JH, Choi CG, Ko Y, Kim HS, Park SH.

JMIR Med Inform. 2019 Aug 30;7(3):e14310. doi: 10.2196/14310.

18.

Practical Considerations for Data Collection and Management in Mobile Health Micro-randomized Trials.

Seewald NJ, Smith SN, Lee AJ, Klasnja P, Murphy SA.

Stat Biosci. 2019 Jul;11(2):355-370. doi: 10.1007/s12561-018-09228-w. Epub 2019 Jan 5.

PMID:
31462937
19.

Insurance Status and Access to Sexual Health Services Among At-Risk Men: A Qualitative Study.

Sowemimo-Coker G, Lee AJ, Montgomery MC, Nunn AS, van den Berg JJ, Chan PA.

J Assoc Nurses AIDS Care. 2019 Sep-Oct;30(5):e122-e131. doi: 10.1097/JNC.0000000000000063.

PMID:
31461742
20.

Chronic Pain Patients' Gaze Patterns toward Pain-Related Information: Comparison between Pictorial and Linguistic Stimuli.

Lee J, Beom J, Choi S, Lee S, Lee AJ.

Medicina (Kaunas). 2019 Aug 25;55(9). pii: E530. doi: 10.3390/medicina55090530.

21.

Outcomes for urologic oncology procedures: are there differences between academic and community hospitals?

Syed JS, Abello A, Nguyen J, Lee AJH, Desloges JJ, Leapman MS, Kenney PA.

World J Urol. 2019 Aug 16. doi: 10.1007/s00345-019-02902-8. [Epub ahead of print]

PMID:
31420696
22.

Simulation Training in the ICU.

Seam N, Lee AJ, Vennero M, Emlet L.

Chest. 2019 Jul 30. pii: S0012-3692(19)31385-6. doi: 10.1016/j.chest.2019.07.011. [Epub ahead of print] Review.

PMID:
31374210
23.

Composition of airway bacterial community correlates with chest HRCT in adults with bronchiectasis.

O'Neill K, Einarsson GG, Rowan S, McIlreavey L, Lee AJ, Lawson J, Lynch T, Horsley A, Bradley JM, Elborn JS, Tunney MM.

Respirology. 2019 Jul 30. doi: 10.1111/resp.13653. [Epub ahead of print]

PMID:
31364220
24.

A quality improvement curriculum for the neurology clerkship: A practice-based approach to discharge education.

McInnis RP, Lee AJ, Schwartz B, Fazal M, Hohler A.

eNeurologicalSci. 2019 Jun 21;16:100196. doi: 10.1016/j.ensci.2019.100196. eCollection 2019 Sep.

25.

DNA nanostructures: A versatile lab-bench for interrogating biological reactions.

Lee AJ, Wälti C.

Comput Struct Biotechnol J. 2019 Jun 14;17:832-842. doi: 10.1016/j.csbj.2019.06.013. eCollection 2019. Review.

26.

Advances in whole body MRI for musculoskeletal imaging: Diffusion-weighted imaging.

Lee K, Park HY, Kim KW, Lee AJ, Yoon MA, Chae EJ, Lee JH, Chung HW.

J Clin Orthop Trauma. 2019 Jul-Aug;10(4):680-686. doi: 10.1016/j.jcot.2019.05.018. Epub 2019 May 29. Review.

PMID:
31316239
27.

Spin-Hall Topological Hall Effect in Highly Tunable Pt/Ferrimagnetic-Insulator Bilayers.

Ahmed AS, Lee AJ, Bagués N, McCullian BA, Thabt AMA, Perrine A, Wu PK, Rowland JR, Randeria M, Hammel PC, McComb DW, Yang F.

Nano Lett. 2019 Aug 14;19(8):5683-5688. doi: 10.1021/acs.nanolett.9b02265. Epub 2019 Jul 19.

PMID:
31310542
28.

Optimal Surveillance Frequency After CRS/HIPEC for Appendiceal and Colorectal Neoplasms: A Multi-institutional Analysis of the US HIPEC Collaborative.

Gamboa AC, Zaidi MY, Lee RM, Speegle S, Switchenko JM, Lipscomb J, Cloyd JM, Ahmed A, Grotz T, Leiting J, Fournier K, Lee AJ, Dineen S, Powers BD, Lowy AM, Kotha NV, Clarke C, Gamblin TC, Patel SH, Lee TC, Lambert L, Hendrix RJ, Abbott DE, Vande Walle K, Lafaro K, Lee B, Johnston FM, Greer J, Russell MC, Staley CA, Maithel SK.

Ann Surg Oncol. 2019 Jun 26. doi: 10.1245/s10434-019-07526-1. [Epub ahead of print]

PMID:
31243668
29.

Compound heterozygous mutations of SH3TC2 in Charcot-Marie-Tooth disease type 4C patients.

Lee AJ, Nam SH, Park JM, Kanwal S, Choi YJ, Lee HJ, Lee KS, Lee JE, Park JS, Choi BO, Chung KW.

J Hum Genet. 2019 Sep;64(9):961-965. doi: 10.1038/s10038-019-0636-y. Epub 2019 Jun 21.

PMID:
31227790
30.

Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production.

Lee AJ, Mian F, Poznanski SM, Stackaruk M, Chan T, Chew MV, Ashkar AA.

Front Immunol. 2019 Jun 4;10:1261. doi: 10.3389/fimmu.2019.01261. eCollection 2019.

31.

Intensity of chemotherapy for the initial management of newly diagnosed acute myeloid leukemia in older patients.

Michalski JM, Lyden ER, Lee AJ, Al-Kadhimi ZS, Maness LJ, Gundabolu K, Bhatt VR.

Future Oncol. 2019 Jun;15(17):1989-1995. doi: 10.2217/fon-2019-0001. Epub 2019 Jun 7.

PMID:
31170814
32.

Circulating Tumor Cells and Transforming Growth Factor Beta in Resected Pancreatic Adenocarcinoma.

Vicente D, Lee AJ, Hall CS, Lucci A, Lee JE, Kim MP, Katz MHG, Hurd MW, Maitra A, Rhim Md AD, Tzeng CD.

J Surg Res. 2019 Nov;243:90-99. doi: 10.1016/j.jss.2019.04.090. Epub 2019 Jun 3.

PMID:
31170555
33.

Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma.

Murchie P, Masthoff J, Walter FM, Rahman K, Allan JL, Burrows N, Proby C, Lee AJ, Johnston M, Durrani A, Depasquale I, Brant B, Neilson A, Meredith F, Treweek S, Hall S, McDonald A.

Trials. 2019 Jun 3;20(1):318. doi: 10.1186/s13063-019-3453-x.

34.

Are Sex Differences in Preferences for Physical Attractiveness and Good Earning Capacity in Potential Mates Smaller in Countries With Greater Gender Equality?

Zhang L, Lee AJ, DeBruine LM, Jones BC.

Evol Psychol. 2019 Apr-Jun;17(2):1474704919852921. doi: 10.1177/1474704919852921.

PMID:
31146580
35.

Predicting the chances of having a baby with or without treatment at different time points in couples with unexplained subfertility.

McLernon DJ, Lee AJ, Maheshwari A, van Eekelen R, van Geloven N, Putter H, Eijkemans MJ, van der Steeg JW, van der Veen F, Steyerberg EW, Mol BW, Bhattacharya S.

Hum Reprod. 2019 Jun 4;34(6):1126-1138. doi: 10.1093/humrep/dez049.

PMID:
31119290
36.

Statin use and risk of liver cancer: Evidence from two population-based studies.

Tran KT, McMenamin ÚC, Coleman HG, Cardwell CR, Murchie P, Iversen L, Lee AJ, Thrift AP.

Int J Cancer. 2019 May 21. doi: 10.1002/ijc.32426. [Epub ahead of print]

PMID:
31112291
37.

A Data-Driven Test for Cross-Cultural Differences in Face Preferences.

Zhang L, Holzleitner IJ, Lee AJ, Wang H, Han C, Fasolt V, DeBruine LM, Jones BC.

Perception. 2019 Jun;48(6):487-499. doi: 10.1177/0301006619849382. Epub 2019 May 8.

PMID:
31068092
38.

Cartilage Wear Particles Induce an Inflammatory Response Similar to Cytokines in Human Fibroblast-Like Synoviocytes.

Estell EG, Silverstein AM, Stefani RM, Lee AJ, Murphy LA, Shah RP, Ateshian GA, Hung CT.

J Orthop Res. 2019 Sep;37(9):1979-1987. doi: 10.1002/jor.24340. Epub 2019 May 17.

PMID:
31062877
39.

A single-frequency intracavity Raman laser.

Sheng Q, Li R, Lee AJ, Spence DJ, Pask HM.

Opt Express. 2019 Mar 18;27(6):8540-8553. doi: 10.1364/OE.27.008540.

PMID:
31052669
40.

Selective purging of human multiple myeloma cells from peripheral blood mononuclear cells: a preliminary study.

Lee AJ, Kim SG.

J Blood Med. 2019 Apr 11;10:105-109. doi: 10.2147/JBM.S193467. eCollection 2019.

41.

Clinical, genetic, and pathologic characterization of FKRP Mexican founder mutation c.1387A>G.

Lee AJ, Jones KA, Butterfield RJ, Cox MO, Konersman CG, Grosmann C, Abdenur JE, Boyer M, Beson B, Wang C, Dowling JJ, Gibbons MA, Ballard A, Janas JS, Leshner RT, Donkervoort S, Bönnemann CG, Malicki DM, Weiss RB, Moore SA, Mathews KD.

Neurol Genet. 2019 Mar 1;5(2):e315. doi: 10.1212/NXG.0000000000000315. eCollection 2019 Apr.

42.

Mating Strategies and the Masculinity Paradox: How Relationship Context, Relationship Status, and Sociosexuality Shape Women's Preferences for Facial Masculinity and Beardedness.

Stower RE, Lee AJ, McIntosh TL, Sidari MJ, Sherlock JM, Dixson BJW.

Arch Sex Behav. 2019 Apr 23. doi: 10.1007/s10508-019-1437-2. [Epub ahead of print]

PMID:
31016490
43.

Primary Tumor Sidedness is Predictive of Survival in Colon Cancer Patients Treated with Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy: A US HIPEC Collaborative Study.

Kotha NV, Baumgartner JM, Veerapong J, Cloyd JM, Ahmed A, Grotz TE, Leiting JL, Fournier K, Lee AJ, Dineen SP, Dessureault S, Clarke C, Mogal H, Zaidi MY, Russell MC, Patel SH, Sussman JJ, Dhar V, Lambert LA, Hendrix RJ, Abbott DE, Pokrzywa C, Lafaro K, Lee B, Greer JB, Fackche N, Lowy AM, Kelly KJ.

Ann Surg Oncol. 2019 Jul;26(7):2234-2240. doi: 10.1245/s10434-019-07373-0. Epub 2019 Apr 23.

PMID:
31016486
44.

Mothers are sensitive to men's beards as a potential cue of paternal investment.

Dixson BJW, Kennedy-Costantini S, Lee AJ, Nelson NL.

Horm Behav. 2019 Jul;113:55-66. doi: 10.1016/j.yhbeh.2019.04.005. Epub 2019 May 9.

PMID:
30978339
45.

Exploratory analysis of single 15 min videotaped structured play session of children aged 1 year reveals no differences between father's parenting behaviours whether infants are born prematurely or at term.

Lee AJ.

Evid Based Nurs. 2019 Apr 11. pii: ebnurs-2018-103057. doi: 10.1136/ebnurs-2018-103057. [Epub ahead of print] No abstract available.

PMID:
30975690
46.

A new class of constitutively active super-enhancers is associated with fast recovery of 3D chromatin loops.

Ryu J, Kim H, Yang D, Lee AJ, Jung I.

BMC Bioinformatics. 2019 Mar 29;20(Suppl 3):127. doi: 10.1186/s12859-019-2646-3.

47.

Women's preferences for men's facial masculinity are strongest under favorable ecological conditions.

Marcinkowska UM, Rantala MJ, Lee AJ, Kozlov MV, Aavik T, Cai H, Contreras-Garduño J, David OA, Kaminski G, Li NP, Onyishi IE, Prasai K, Pazhoohi F, Prokop P, Cardozo SLR, Sydney N, Taniguchi H, Krams I, Dixson BJW.

Sci Rep. 2019 Mar 4;9(1):3387. doi: 10.1038/s41598-019-39350-8.

48.

Is early-stage pancreatic adenocarcinoma truly early: stage migration on final pathology with surgery-first versus neoadjuvant therapy sequencing.

Lee AJ, Simoneau E, Chiang YJ, Lee JE, Kim MP, Aloia TA, Vauthey JN, Katz MH, Tzeng CD.

HPB (Oxford). 2019 Sep;21(9):1203-1210. doi: 10.1016/j.hpb.2019.01.011. Epub 2019 Feb 22.

PMID:
30799277
49.

The effects of human factor related issues on assessors during the recruitment process for general and vascular surgery in the UK.

Scrimgeour D, Patel R, Patel N, Cleland J, Lee AJ, McKinley AJ, Smith F, Griffiths G, Brennan PA.

Ann R Coll Surg Engl. 2019 Apr;101(4):231-234. doi: 10.1308/rcsann.2019.0008. Epub 2019 Feb 18.

PMID:
30773892
50.

Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant.

Nelson SR, Kathe SD, Hilzinger TS, Averill AM, Warshaw DM, Wallace SS, Lee AJ.

Nucleic Acids Res. 2019 Apr 8;47(6):3058-3071. doi: 10.1093/nar/gkz045.

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