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Jump Training in Rugby Union Players: Barbell or Hexagonal Bar?

Weakley JJS, Till K, Read DB, Leduc C, Roe GAB, Phibbs PJ, Darrall-Jones J, Jones B.

J Strength Cond Res. 2018 Jul 4. doi: 10.1519/JSC.0000000000002742. [Epub ahead of print]


Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts.

De Pascalis C, Pérez-González C, Seetharaman S, Boëda B, Vianay B, Burute M, Leduc C, Borghi N, Trepat X, Etienne-Manneville S.

J Cell Biol. 2018 Jul 6. pii: jcb.201801162. doi: 10.1083/jcb.201801162. [Epub ahead of print]


Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function.

Xu Z, Lo WS, Beck DB, Schuch LA, Oláhová M, Kopajtich R, Chong YE, Alston CL, Seidl E, Zhai L, Lau CF, Timchak D, LeDuc CA, Borczuk AC, Teich AF, Juusola J, Sofeso C, Müller C, Pierre G, Hilliard T, Turnpenny PD, Wagner M, Kappler M, Brasch F, Bouffard JP, Nangle LA, Yang XL, Zhang M, Taylor RW, Prokisch H, Griese M, Chung WK, Schimmel P.

Am J Hum Genet. 2018 Jul 5;103(1):100-114. doi: 10.1016/j.ajhg.2018.06.006.


Training Periodization Over an Elite Rugby Sevens Season: From Theory to Practice.

Marrier B, Le Meur Y, Leduc C, Piscione J, Lacome M, Igarza G, Hausswirth C, Morin JB, Robineau J.

Int J Sports Physiol Perform. 2018 Jun 28:1-24. doi: 10.1123/ijspp.2017-0839. [Epub ahead of print]


Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding.

Ravussin Y, Edwin E, Gallop M, Xu L, Bartolomé A, Kraakman MJ, LeDuc CA, Ferrante AW Jr.

Cell Metab. 2018 Jun 14. pii: S1550-4131(18)30382-6. doi: 10.1016/j.cmet.2018.05.029. [Epub ahead of print]


FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via modifications of DNA N6-methyldeoxyadenosine.

Martin Carli JF, LeDuc CA, Zhang Y, Stratigopoulos G, Leibel RL.

J Lipid Res. 2018 Jun 22. pii: jlr.M085555. doi: 10.1194/jlr.M085555. [Epub ahead of print]


DMSO increases efficiency of genome editing at two non-coding loci.

Stratigopoulos G, De Rosa MC, LeDuc CA, Leibel RL, Doege CA.

PLoS One. 2018 Jun 4;13(6):e0198637. doi: 10.1371/journal.pone.0198637. eCollection 2018.


ILDR2 has a negligible role in hepatic steatosis.

Millings EJ, De Rosa MC, Fleet S, Watanabe K, Rausch R, Egli D, Li G, Leduc CA, Zhang Y, Fischer SG, Leibel RL.

PLoS One. 2018 May 30;13(5):e0197548. doi: 10.1371/journal.pone.0197548. eCollection 2018.


SNAI2 and TWIST1 in lymph node progression in early stages of NSCLC patients.

Emprou C, Le Van Quyen P, Jégu J, Prim N, Weingertner N, Guérin E, Pencreach E, Legrain M, Voegeli AC, Leduc C, Mennecier B, Falcoz PE, Olland A, Santelmo N, Quoix E, Massard G, Guenot D, Chenard MP, Beau-Faller M.

Cancer Med. 2018 May 29. doi: 10.1002/cam4.1545. [Epub ahead of print]


Advancing Indigenous primary health care policy in Alberta, Canada.

Henderson R, Montesanti S, Crowshoe L, Leduc C.

Health Policy. 2018 Jun;122(6):638-644. doi: 10.1016/j.healthpol.2018.04.014. Epub 2018 May 7.


Spontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14.

Dupont L, Ehx G, Chantry M, Monseur C, Leduc C, Janssen L, Cataldo D, Thiry M, Jerome C, Thomassin JM, Nusgens B, Dubail J, Baron F, Colige A.

Matrix Biol. 2018 Apr 9. pii: S0945-053X(17)30441-9. doi: 10.1016/j.matbio.2018.04.002. [Epub ahead of print]


Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy.

Leduc C, Salles A, Shorte SL, Etienne-Manneville S.

J Vis Exp. 2018 Mar 6;(133). doi: 10.3791/57087.


The role of Rpgrip1l, a component of the primary cilium, in adipocyte development and function.

Carli JFM, LeDuc CA, Zhang Y, Stratigopoulos G, Leibel RL.

FASEB J. 2018 Jul;32(7):3946-3956. doi: 10.1096/fj.201701216R. Epub 2018 Feb 21.


TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma.

Leduc C, Adam J, Louvet E, Sourisseau T, Dorvault N, Bernard M, Maingot E, Faivre L, Cassin-Kuo MS, Boissier E, Dessoliers MC, Robin A, Casiraghi O, Even C, Temam S, Olaussen KA, Soria JC, Postel-Vinay S.

ESMO Open. 2018 Jan 9;3(1):e000257. doi: 10.1136/esmoopen-2017-000257. eCollection 2018.


Outcome of EGFR-mutated NSCLC patients with MET-driven resistance to EGFR tyrosine kinase inhibitors.

Baldacci S, Mazieres J, Tomasini P, Girard N, Guisier F, Audigier-Valette C, Monnet I, Wislez M, Pérol M, Dô P, Dansin E, Leduc C, Leprieur EG, Moro-Sibilot D, Tulasne D, Kherrouche Z, Labreuche J, Cortot AB.

Oncotarget. 2017 Oct 9;8(62):105103-105114. doi: 10.18632/oncotarget.21707. eCollection 2017 Dec 1.


Energy homeostasis in leptin deficient Lepob/ob mice.

Skowronski AA, Ravussin Y, Leibel RL, LeDuc CA.

PLoS One. 2017 Dec 20;12(12):e0189784. doi: 10.1371/journal.pone.0189784. eCollection 2017.


Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots.

Baudhuin LM, Leduc C, Train LJ, Avula R, Kluge ML, Kotzer KE, Lin PT, Ackerman MJ, Maleszewski JJ.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001844. doi: 10.1161/CIRCGENETICS.117.001844.


Sleep Quantity and Quality of Ontario Wildland Firefighters Across a Low-Hazard Fire Season.

McGillis Z, Dorman SC, Robertson A, Larivière M, Leduc C, Eger T, Oddson BE, Larivière C.

J Occup Environ Med. 2017 Dec;59(12):1188-1196. doi: 10.1097/JOM.0000000000001175.


Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems.

Nagaria TS, Shi C, Leduc C, Hoskin V, Sikdar S, Sangrar W, Greer PA.

Oncotarget. 2017 Aug 24;8(46):80804-80819. doi: 10.18632/oncotarget.20534. eCollection 2017 Oct 6.


Loss of the imprinted, non-coding Snord116 gene cluster in the interval deleted in the Prader Willi syndrome results in murine neuronal and endocrine pancreatic developmental phenotypes.

Burnett LC, Hubner G, LeDuc CA, Morabito MV, Carli JFM, Leibel RL.

Hum Mol Genet. 2017 Dec 1;26(23):4606-4616. doi: 10.1093/hmg/ddx342.


Clinical and molecular characteristics of non-small-cell lung cancer (NSCLC) harboring EGFR mutation: results of the nationwide French Cooperative Thoracic Intergroup (IFCT) program.

Leduc C, Merlio JP, Besse B, Blons H, Debieuvre D, Bringuier PP, Monnet I, Rouquette I, Fraboulet-Moreau S, Lemoine A, Pouessel D, Mosser J, Vaylet F, Langlais A, Missy P, Morin F, Moro-Sibilot D, Cadranel J, Barlesi F, Beau-Faller M; French Cooperative Thoracic Intergroup (IFCT).

Ann Oncol. 2017 Nov 1;28(11):2715-2724. doi: 10.1093/annonc/mdx404.


Case study: sleep and injury in elite soccer. A mixed method approach.

Nédélec M, Leduc C, Dawson B, Guilhem G, Dupont G.

J Strength Cond Res. 2017 Sep 11. doi: 10.1519/JSC.0000000000002251. [Epub ahead of print]


Intermediate filaments join the action.

Leduc C, Etienne-Manneville S.

Cell Cycle. 2017 Aug 3;16(15):1389-1390. doi: 10.1080/15384101.2017.1345230. Epub 2017 Jul 19. No abstract available.


Immune-related bone marrow failure following anti-PD1 therapy.

Michot JM, Vargaftig J, Leduc C, Quere G, Burroni B, Lazarovici J, Champiat S, Ribrag V, Lambotte O.

Eur J Cancer. 2017 Jul;80:1-4. doi: 10.1016/j.ejca.2017.04.004. Epub 2017 May 17. No abstract available.


Regulation of microtubule-associated motors drives intermediate filament network polarization.

Leduc C, Etienne-Manneville S.

J Cell Biol. 2017 Jun 5;216(6):1689-1703. doi: 10.1083/jcb.201607045. Epub 2017 Apr 21.


Comorbidities in the management of patients with lung cancer.

Leduc C, Antoni D, Charloux A, Falcoz PE, Quoix E.

Eur Respir J. 2017 Mar 29;49(3). pii: 1601721. doi: 10.1183/13993003.01721-2016. Print 2017 Mar. Review.


Curcumin and Piperine Supplementation and Recovery Following Exercise Induced Muscle Damage: A Randomized Controlled Trial.

Delecroix B, Abaïdia AE, Leduc C, Dawson B, Dupont G.

J Sports Sci Med. 2017 Mar 1;16(1):147-153. eCollection 2017 Mar.


Personal Exposimeter for Radiation Assessment in Real Environments in the 60-GHz Band.

Aminzadeh R, Thielens A, Li H, Leduc C, Zhadobov M, Torfs G, Bauwelinck J, Martens L, Joseph W.

Radiat Prot Dosimetry. 2017 Nov 1;176(3):316-321. doi: 10.1093/rpd/ncx012.


Novel Tools in Determining the Physiological Demands and Nutritional Practices of Ontario FireRangers during Fire Deployments.

Robertson AH, Larivière C, Leduc CR, McGillis Z, Eger T, Godwin A, Larivière M, Dorman SC.

PLoS One. 2017 Jan 20;12(1):e0169390. doi: 10.1371/journal.pone.0169390. eCollection 2017.


Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain.

Morabito MV, Ravussin Y, Mueller BR, Skowronski AA, Watanabe K, Foo KS, Lee SX, Lehmann A, Hjorth S, Zeltser LM, LeDuc CA, Leibel RL.

PLoS One. 2017 Jan 20;12(1):e0168226. doi: 10.1371/journal.pone.0168226. eCollection 2017.


iPSC-derived β cells model diabetes due to glucokinase deficiency.

Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, LeDuc C, Chung WK, Goland R, Leibel RL, Egli D.

J Clin Invest. 2017 Mar 1;127(3):1115. doi: 10.1172/JCI92775. Epub 2017 Jan 17. No abstract available.


Determination of the half-life of circulating leptin in the mouse.

Burnett LC, Skowronski AA, Rausch R, LeDuc CA, Leibel RL.

Int J Obes (Lond). 2017 Mar;41(3):355-359. doi: 10.1038/ijo.2016.238. Epub 2016 Dec 27.


Programmed death of chemotherapy in non-small-cell lung cancer?

Leduc C, Quoix E.

Lancet. 2017 Jan 21;389(10066):227-228. doi: 10.1016/S0140-6736(16)32535-1. Epub 2016 Dec 13. No abstract available.


The subgingival microbiome, systemic inflammation and insulin resistance: The Oral Infections, Glucose Intolerance and Insulin Resistance Study.

Demmer RT, Breskin A, Rosenbaum M, Zuk A, LeDuc C, Leibel R, Paster B, Desvarieux M, Jacobs DR Jr, Papapanou PN.

J Clin Periodontol. 2017 Mar;44(3):255-265. doi: 10.1111/jcpe.12664. Epub 2017 Jan 27.


Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome.

Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL.

J Clin Invest. 2017 Jan 3;127(1):293-305. doi: 10.1172/JCI88648. Epub 2016 Dec 12.


Cardiac angiosarcoma: histopathologic, immunohistochemical, and cytogenetic analysis of 10 cases.

Leduc C, Jenkins SM, Sukov WR, Rustin JG, Maleszewski JJ.

Hum Pathol. 2017 Feb;60:199-207. doi: 10.1016/j.humpath.2016.10.014. Epub 2016 Nov 4.


Diagnosis of Jejunal Metastases from Lung Cancer Using Capsule Endoscopy.

Leduc C, Prim N, Mennecier B, Delvaux M, Gangi A, Quoix E.

Case Rep Oncol. 2016 Sep 13;9(3):526-529. eCollection 2016 Sep-Dec.


Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS.

Burnett LC, LeDuc CA, Sulsona CR, Paull D, Eddiry S, Levy B, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL.

Stem Cell Res. 2016 Nov;17(3):526-530. doi: 10.1016/j.scr.2016.08.008. Epub 2016 Aug 16.


Misconceptions About Malignant Metamorphosis in Myxoma.

Leduc C, Maleszewski JJ.

Ann Thorac Surg. 2016 Nov;102(5):1766. doi: 10.1016/j.athoracsur.2016.04.070. No abstract available.


Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.

Naidoo J, Wang X, Woo KM, Iyriboz T, Halpenny D, Cunningham J, Chaft JE, Segal NH, Callahan MK, Lesokhin AM, Rosenberg J, Voss MH, Rudin CM, Rizvi H, Hou X, Rodriguez K, Albano M, Gordon RA, Leduc C, Rekhtman N, Harris B, Menzies AM, Guminski AD, Carlino MS, Kong BY, Wolchok JD, Postow MA, Long GV, Hellmann MD.

J Clin Oncol. 2017 Mar;35(7):709-717. doi: 10.1200/JCO.2016.68.2005. Epub 2016 Sep 30.


[Prolonged response with paclitaxel after immunotherapy by pembrolizumab in lung cancer].

Zapata E, Mennecier B, Leduc C, Chatron E, Quoix E.

Rev Pneumol Clin. 2016 Oct;72(5):300-304. doi: 10.1016/j.pneumo.2016.05.004. Epub 2016 Aug 22. French.


Recovery From Exercise-Induced Muscle Damage: Cold-Water Immersion Versus Whole-Body Cryotherapy.

Abaïdia AE, Lamblin J, Delecroix B, Leduc C, McCall A, Nédélec M, Dawson B, Baquet G, Dupont G.

Int J Sports Physiol Perform. 2017 Mar;12(3):402-409. doi: 10.1123/ijspp.2016-0186. Epub 2016 Aug 24.


ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression.

Watanabe K, Nakayama K, Ohta S, Tago K, Boonvisut S, Millings EJ, Fischer SG, LeDuc CA, Leibel RL, Iwamoto S.

Biochem Biophys Res Commun. 2016 Sep 2;477(4):712-716. doi: 10.1016/j.bbrc.2016.06.124. Epub 2016 Jun 25.


Effects of a Strength Training Session After an Exercise Inducing Muscle Damage on Recovery Kinetics.

Abaïdia AE, Delecroix B, Leduc C, Lamblin J, McCall A, Baquet G, Dupont G.

J Strength Cond Res. 2017 Jan;31(1):115-125. doi: 10.1519/JSC.0000000000001479.


Late durability of decellularized allografts for aortic valve replacement: A word of caution.

Helder MR, Kouchoukos NT, Zehr K, Dearani JA, Maleszewski JJ, Leduc C, Heins CN, Schaff HV.

J Thorac Cardiovasc Surg. 2016 Oct;152(4):1197-9. doi: 10.1016/j.jtcvs.2016.03.050. Epub 2016 Mar 31. No abstract available.


Hypomorphism of Fto and Rpgrip1l causes obesity in mice.

Stratigopoulos G, Burnett LC, Rausch R, Gill R, Penn DB, Skowronski AA, LeDuc CA, Lanzano AJ, Zhang P, Storm DR, Egli D, Leibel RL.

J Clin Invest. 2016 May 2;126(5):1897-910. doi: 10.1172/JCI85526. Epub 2016 Apr 11.


Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy.

Harel T, Yesil G, Bayram Y, Coban-Akdemir Z, Charng WL, Karaca E, Al Asmari A, Eldomery MK, Hunter JV, Jhangiani SN, Rosenfeld JA, Pehlivan D, El-Hattab AW, Saleh MA, LeDuc CA, Muzny D, Boerwinkle E; Baylor-Hopkins Center for Mendelian Genomics, Gibbs RA, Chung WK, Yang Y, Belmont JW, Lupski JR.

Am J Hum Genet. 2016 Mar 3;98(3):562-570. doi: 10.1016/j.ajhg.2016.01.011.


TGF-beta-induced early gene-1 overexpression promotes oxidative stress protection and actin cytoskeleton rearrangement in human skin fibroblasts.

Leduc C, Sobilo L, Toumi H, Mondon P, Lespessailles E, Ossant F, Kurfurst R, Pichon C.

Biochim Biophys Acta. 2016 Jun;1860(6):1071-8. doi: 10.1016/j.bbagen.2016.02.009. Epub 2016 Feb 23.


Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ.

Nat Commun. 2016 Feb 1;7:10494. doi: 10.1038/ncomms10494.


Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets.

Bekhouche M, Leduc C, Dupont L, Janssen L, Delolme F, Vadon-Le Goff S, Smargiasso N, Baiwir D, Mazzucchelli G, Zanella-Cleon I, Dubail J, De Pauw E, Nusgens B, Hulmes DJ, Moali C, Colige A.

FASEB J. 2016 May;30(5):1741-56. doi: 10.1096/fj.15-279869. Epub 2016 Jan 6.


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