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Items: 36

1.

Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.

Dy ABC, Arif MZ, Addison KJ, Que LG, Boitano S, Kraft M, Ledford JG.

J Immunol. 2019 Jul 26. pii: ji1900546. doi: 10.4049/jimmunol.1900546. [Epub ahead of print]

PMID:
31350355
2.

Translational Medicine in the Era of Social Media: A Survey of Scientific and Clinical Communities.

Sandalova E, Ledford JG, Baskaran M, Dijkstra S.

Front Med (Lausanne). 2019 Jul 3;6:152. doi: 10.3389/fmed.2019.00152. eCollection 2019.

3.

Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma.

Younis US, Vallorz E, Addison KJ, Ledford JG, Myrdal PB.

AAPS PharmSciTech. 2019 Apr 16;20(5):167. doi: 10.1208/s12249-019-1377-0.

PMID:
30993508
4.

Tollip Inhibits ST2 Signaling in Airway Epithelial Cells Exposed to Type 2 Cytokines and Rhinovirus.

Dakhama A, Al Mubarak R, Pavelka N, Voelker D, Seibold M, Ledford JG, Kraft M, Li L, Chu HW.

J Innate Immun. 2019 Mar 29:1-13. doi: 10.1159/000497072. [Epub ahead of print]

5.

Possibilities and Pitfalls of Social Media for Translational Medicine.

Dijkstra S, Kok G, Ledford JG, Sandalova E, Stevelink R.

Front Med (Lausanne). 2018 Dec 6;5:345. doi: 10.3389/fmed.2018.00345. eCollection 2018.

6.

Club Cell Secretory Protein Deficiency Leads to Altered Lung Function.

Zhai J, Insel M, Addison KJ, Stern DA, Pederson W, Dy A, Rojas-Quintero J, Owen CA, Sherrill DL, Morgan W, Wright AL, Halonen M, Martinez FD, Kraft M, Guerra S, Ledford JG.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):302-312. doi: 10.1164/rccm.201807-1345OC.

PMID:
30543455
7.

The Emerging Roles of Surfactant Protein-A in Asthma.

Dy ABC, Tanyaratsrisakul S, Voelker DR, Ledford JG.

J Clin Cell Immunol. 2018;9(4). pii: 553. doi: 10.4172/2155-9899.1000553. Epub 2018 Jul 16.

8.

Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice.

Ito Y, Schaefer N, Sanchez A, Francisco D, Alam R, Martin RJ, Ledford JG, Stevenson C, Jiang D, Li L, Kraft M, Chu HW.

J Innate Immun. 2018;10(2):106-118. doi: 10.1159/000485850. Epub 2018 Jan 27.

9.

Novel role of surfactant protein A in bacterial sinusitis.

Noutsios GT, Willis AL, Ledford JG, Chang EH.

Int Forum Allergy Rhinol. 2017 Sep;7(9):897-903. doi: 10.1002/alr.21985. Epub 2017 Jul 20.

10.

Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications.

Lugogo N, Francisco D, Addison KJ, Manne A, Pederson W, Ingram JL, Green CL, Suratt BT, Lee JJ, Sunday ME, Kraft M, Ledford JG.

J Allergy Clin Immunol. 2018 Mar;141(3):918-926.e3. doi: 10.1016/j.jaci.2017.05.028. Epub 2017 Jun 15.

11.

A Novel in vivo System to Test Bronchodilators.

Addison KJ, Morse J, Robichaud A, Daines MO, Ledford JG.

J Infect Pulm Dis. 2017 Mar;3(1). doi: 10.16966/2470-3176.120. Epub 2017 Feb 3.

12.

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.

Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, von Mutius E, Vercelli D, Ober C, Sperling AI.

N Engl J Med. 2016 Aug 4;375(5):411-421. doi: 10.1056/NEJMoa1508749.

13.

Tollip SNP rs5743899 modulates human airway epithelial responses to rhinovirus infection.

Huang C, Jiang D, Francisco D, Berman R, Wu Q, Ledford JG, Moore CM, Ito Y, Stevenson C, Munson D, Li L, Kraft M, Chu HW.

Clin Exp Allergy. 2016 Dec;46(12):1549-1563. doi: 10.1111/cea.12793. Epub 2016 Sep 21.

14.

Genetic Variation in Surfactant Protein-A2 Results in Altered Regulation of Eosinophil Activities and Enhanced Eosinophilia in Patients with Asthma.

Ledford JG, Addison KJ, Francisco D, Foster MW, Voelker DR, Que LG, Kraft M.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S101. doi: 10.1513/AnnalsATS.201508-520MG. No abstract available.

15.

Correction notice for TNF-R on mast cells regulate airway responses to Mycoplasma pneumoniae.

Hsia BJ, Ledford JG, Potts-Kant EN, Nikam VS, Lugogo NL, Foster WM, Kraft M, Abraham SN, Wright JR.

J Allergy Clin Immunol. 2016 Jan;137(1):336. doi: 10.1016/j.jaci.2015.09.049. Epub 2015 Nov 21. No abstract available.

16.

Correction: SP-A Preserves Airway Homeostasis during Mycoplasma pneumoniae Infection in Mice.

Ledford JG, Goto H, Potts EN, Degan S, Wei Chu H, Voelker DR, Sunday ME, Cianciolo GJ, Foster WM, Kraft M, Wright JR.

J Immunol. 2015 Sep 15;195(6):2917-8. doi: 10.4049/jimmunol.1501597. No abstract available.

17.

Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses.

Ledford JG, Voelker DR, Addison KJ, Wang Y, Nikam VS, Degan S, Kandasamy P, Tanyaratsrisakul S, Fischer BM, Kraft M, Hollingsworth JW.

J Immunol. 2015 Jun 15;194(12):6123-32. doi: 10.4049/jimmunol.1500104. Epub 2015 May 8.

18.

Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β.

Ogawa H, Ledford JG, Mukherjee S, Aono Y, Nishioka Y, Lee JJ, Izumi K, Hollingsworth JW.

Respir Res. 2014 Nov 29;15:143. doi: 10.1186/s12931-014-0143-9.

19.

Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.

Foster MW, Thompson JW, Ledford JG, Dubois LG, Hollingsworth JW, Francisco D, Tanyaratsrisakul S, Voelker DR, Kraft M, Moseley MA, Foster WM.

J Proteome Res. 2014 Aug 1;13(8):3722-32. doi: 10.1021/pr500307f. Epub 2014 Jul 15.

20.

Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help?

Ledford JG, Addison KJ, Foster MW, Que LG.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):604-14. doi: 10.1165/rcmb.2014-0095TR. Review.

21.

Impact of surfactant protein D, interleukin-5, and eosinophilia on Cryptococcosis.

Holmer SM, Evans KS, Asfaw YG, Saini D, Schell WA, Ledford JG, Frothingham R, Wright JR, Sempowski GD, Perfect JR.

Infect Immun. 2014 Feb;82(2):683-93. doi: 10.1128/IAI.00855-13. Epub 2013 Nov 25.

22.

Surfactant protein A suppresses lung cancer progression by regulating the polarization of tumor-associated macrophages.

Mitsuhashi A, Goto H, Kuramoto T, Tabata S, Yukishige S, Abe S, Hanibuchi M, Kakiuchi S, Saijo A, Aono Y, Uehara H, Yano S, Ledford JG, Sone S, Nishioka Y.

Am J Pathol. 2013 May;182(5):1843-53. doi: 10.1016/j.ajpath.2013.01.030. Epub 2013 Mar 14.

23.

Genes of innate immunity and the biological response to inhaled ozone.

Li Z, Tighe RM, Feng F, Ledford JG, Hollingsworth JW.

J Biochem Mol Toxicol. 2013 Jan;27(1):3-16. doi: 10.1002/jbt.21453. Epub 2012 Nov 20. Review.

24.

Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice.

Hsia BJ, Ledford JG, Potts-Kant EN, Nikam VS, Lugogo NL, Foster WM, Kraft M, Abraham SN, Wright JR.

J Allergy Clin Immunol. 2012 Jul;130(1):205-14.e2. doi: 10.1016/j.jaci.2012.03.002. Epub 2012 Apr 12.

25.

Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs.

Ledford JG, Mukherjee S, Kislan MM, Nugent JL, Hollingsworth JW, Wright JR.

PLoS One. 2012;7(2):e32436. doi: 10.1371/journal.pone.0032436. Epub 2012 Feb 23.

26.

ONZIN deficiency attenuates contact hypersensitivity responses in mice.

Ledford JG, Kovarova M, Jania LA, Nguyen M, Koller BH.

Immunol Cell Biol. 2012 Aug;90(7):733-42. doi: 10.1038/icb.2011.107. Epub 2012 Jan 17.

27.

Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.

Mukherjee S, Giamberardino C, Thomas J, Evans K, Goto H, Ledford JG, Hsia B, Pastva AM, Wright JR.

J Immunol. 2012 Feb 1;188(3):957-67. doi: 10.4049/jimmunol.1100461. Epub 2012 Jan 4.

28.

Surfactant protein-D regulates effector cell function and fibrotic lung remodeling in response to bleomycin injury.

Aono Y, Ledford JG, Mukherjee S, Ogawa H, Nishioka Y, Sone S, Beers MF, Noble PW, Wright JR.

Am J Respir Crit Care Med. 2012 Mar 1;185(5):525-36. doi: 10.1164/rccm.201103-0561OC. Epub 2011 Dec 28.

29.

Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.

Jimenez-Preitner M, Berney X, Uldry M, Vitali A, Cinti S, Ledford JG, Thorens B.

Cell Metab. 2011 Nov 2;14(5):658-70. doi: 10.1016/j.cmet.2011.08.008. Epub 2011 Oct 6.

30.

Surfactant protein-A inhibits mycoplasma-induced dendritic cell maturation through regulation of HMGB-1 cytokine activity.

Ledford JG, Lo B, Kislan MM, Thomas JM, Evans K, Cain DW, Kraft M, Williams KL, Wright JR.

J Immunol. 2010 Oct 1;185(7):3884-94. doi: 10.4049/jimmunol.1000387. Epub 2010 Sep 1.

31.

Review: Collectins link innate and adaptive immunity in allergic airway disease.

Ledford JG, Pastva AM, Wright JR.

Innate Immun. 2010 Jun;16(3):183-90. doi: 10.1177/1753425910368446. Epub 2010 Apr 23. Review.

32.

The role of surfactant protein A in bleomycin-induced acute lung injury.

Goto H, Ledford JG, Mukherjee S, Noble PW, Williams KL, Wright JR.

Am J Respir Crit Care Med. 2010 Jun 15;181(12):1336-44. doi: 10.1164/rccm.200907-1002OC. Epub 2010 Feb 18.

33.

SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.

Ledford JG, Goto H, Potts EN, Degan S, Chu HW, Voelker DR, Sunday ME, Cianciolo GJ, Foster WM, Kraft M, Wright JR.

J Immunol. 2009 Jun 15;182(12):7818-27. doi: 10.4049/jimmunol.0900452. Erratum in: J Immunol. 2015 Sep 15;195(6):2917-8.

34.

Impaired host defense in mice lacking ONZIN.

Ledford JG, Kovarova M, Koller BH.

J Immunol. 2007 Apr 15;178(8):5132-43.

35.

Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease.

Allen IC, Pace AJ, Jania LA, Ledford JG, Latour AM, Snouwaert JN, Bernier V, Stocco R, Therien AG, Koller BH.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1005-17. Epub 2006 Jul 7.

36.

Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups.

Rabinowitz JE, Bowles DE, Faust SM, Ledford JG, Cunningham SE, Samulski RJ.

J Virol. 2004 May;78(9):4421-32.

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