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Items: 42

1.

Combination of experimental and in silico methods for the assessment of the phototransformation products of the antipsychotic drug/metabolite Mesoridazine.

Wilde ML, Menz J, Leder C, Kümmerer K.

Sci Total Environ. 2018 Mar 15;618:697-711. doi: 10.1016/j.scitotenv.2017.08.040. Epub 2017 Oct 19.

PMID:
29055596
2.

Hazard screening of photo-transformation products from pharmaceuticals: Application to selective β1-blockers atenolol and metoprolol.

Toolaram AP, Menz J, Rastogi T, Leder C, Kümmerer K, Schneider M.

Sci Total Environ. 2017 Feb 1;579:1769-1780. doi: 10.1016/j.scitotenv.2016.10.242. Epub 2016 Dec 7.

PMID:
27939084
3.

Transformation products in the water cycle and the unsolved problem of their proactive assessment: A combined in vitro/in silico approach.

Menz J, Toolaram AP, Rastogi T, Leder C, Olsson O, Kümmerer K, Schneider M.

Environ Int. 2017 Jan;98:171-180. doi: 10.1016/j.envint.2016.11.003. Epub 2016 Nov 15.

PMID:
27855972
4.

Photodegradation of the UV filter ethylhexyl methoxycinnamate under ultraviolet light: Identification and in silico assessment of photo-transformation products in the context of grey water reuse.

Jentzsch F, Olsson O, Westphal J, Reich M, Leder C, Kümmerer K.

Sci Total Environ. 2016 Dec 1;572:1092-1100. doi: 10.1016/j.scitotenv.2016.08.017. Epub 2016 Aug 13.

PMID:
27531468
5.

Environmental fate and effect assessment of thioridazine and its transformation products formed by photodegradation.

Wilde ML, Menz J, Trautwein C, Leder C, Kümmerer K.

Environ Pollut. 2016 Jun;213:658-670. doi: 10.1016/j.envpol.2016.03.018. Epub 2016 Mar 25.

PMID:
27020046
6.

Initial hazard screening for genotoxicity of photo-transformation products of ciprofloxacin by applying a combination of experimental and in-silico testing.

Toolaram AP, Haddad T, Leder C, Kümmerer K.

Environ Pollut. 2016 Apr;211:148-56. doi: 10.1016/j.envpol.2015.12.040. Epub 2015 Dec 31.

PMID:
26748250
7.

Degradation of cyclophosphamide and 5-fluorouracil by UV and simulated sunlight treatments: Assessment of the enhancement of the biodegradability and toxicity.

Lutterbeck CA, Wilde ML, Baginska E, Leder C, Machado ÊL, Kümmerer K.

Environ Pollut. 2016 Jan;208(Pt B):467-76. doi: 10.1016/j.envpol.2015.10.016. Epub 2015 Nov 10.

PMID:
26566018
8.

B7-H1 Selectively Controls TH17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway.

Herold M, Posevitz V, Chudyka D, Hucke S, Groß C, Kurth F, Leder C, Loser K, Kurts C, Knolle P, Klotz L, Wiendl H.

J Immunol. 2015 Oct 15;195(8):3584-95. doi: 10.4049/jimmunol.1402746. Epub 2015 Sep 16.

9.

Assessing the environmental fate of S-metolachlor, its commercial product Mercantor Gold® and their photoproducts using a water-sediment test and in silico methods.

Gutowski L, Baginska E, Olsson O, Leder C, Kümmerer K.

Chemosphere. 2015 Nov;138:847-55. doi: 10.1016/j.chemosphere.2015.08.013. Epub 2015 Aug 24.

PMID:
26299980
10.

Re-Designing of Existing Pharmaceuticals for Environmental Biodegradability: A Tiered Approach with β-Blocker Propranolol as an Example.

Rastogi T, Leder C, Kümmerer K.

Environ Sci Technol. 2015 Oct 6;49(19):11756-63. doi: 10.1021/acs.est.5b03051. Epub 2015 Sep 8.

PMID:
26291878
11.

Degradation of 5-FU by means of advanced (photo)oxidation processes: UV/H2O2, UV/Fe2+/H2O2 and UV/TiO2--Comparison of transformation products, ready biodegradability and toxicity.

Lutterbeck CA, Wilde ML, Baginska E, Leder C, Machado ÊL, Kümmerer K.

Sci Total Environ. 2015 Sep 15;527-528:232-45. doi: 10.1016/j.scitotenv.2015.04.111. Epub 2015 May 14.

PMID:
25965036
12.
13.

Designing green derivatives of β-blocker Metoprolol: a tiered approach for green and sustainable pharmacy and chemistry.

Rastogi T, Leder C, Kümmerer K.

Chemosphere. 2014 Sep;111:493-9. doi: 10.1016/j.chemosphere.2014.03.119. Epub 2014 May 22.

PMID:
24997957
14.

Monitoring of methotrexate chlorination in water.

Roig B, Marquenet B, Delpla I, Bessonneau V, Sellier A, Leder C, Thomas O, Bolek R, Kummerer K.

Water Res. 2014 Jun 15;57:67-75. doi: 10.1016/j.watres.2014.03.008. Epub 2014 Mar 19.

15.

Qualitative environmental risk assessment of photolytic transformation products of iodinated X-ray contrast agent diatrizoic acid.

Rastogi T, Leder C, Kümmerer K.

Sci Total Environ. 2014 Jun 1;482-483:378-88. doi: 10.1016/j.scitotenv.2014.02.139. Epub 2014 Mar 22.

PMID:
24662206
16.

Identification of phototransformation products of thalidomide and mixture toxicity assessment: an experimental and quantitative structural activity relationships (QSAR) approach.

Mahmoud WM, Toolaram AP, Menz J, Leder C, Schneider M, Kümmerer K.

Water Res. 2014 Feb 1;49:11-22. doi: 10.1016/j.watres.2013.11.014. Epub 2013 Nov 20.

PMID:
24316178
17.

Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice.

Müller I, Schönberger T, Schneider M, Borst O, Ziegler M, Seizer P, Leder C, Müller K, Lang M, Appenzeller F, Lunov O, Büchele B, Fahrleitner M, Olbrich M, Langer H, Geisler T, Lang F, Chatterjee M, de Boer JF, Tietge UJ, Bernhagen J, Simmet T, Gawaz M.

J Biol Chem. 2013 Nov 1;288(44):31635-45. doi: 10.1074/jbc.M113.477745. Epub 2013 Sep 3.

18.

Aquatic photochemistry, abiotic and aerobic biodegradability of thalidomide: identification of stable transformation products by LC-UV-MS(n).

Mahmoud WM, Trautwein C, Leder C, Kümmerer K.

Sci Total Environ. 2013 Oct 1;463-464:140-50. doi: 10.1016/j.scitotenv.2013.05.082. Epub 2013 Jun 21.

PMID:
23792256
19.

The recombinant bifunctional protein αCD133-GPVI promotes repair of the infarcted myocardium in mice.

Baumer Y, Leder C, Ziegler M, Schönberger T, Ochmann C, Perk A, Degen H, Schmid-Horch B, Elvers M, Münch G, Ungerer M, Schlosshauer B, Gawaz M.

J Thromb Haemost. 2012 Jun;10(6):1152-64. doi: 10.1111/j.1538-7836.2012.04710.x.

20.

The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.

Ziegler M, Elvers M, Baumer Y, Leder C, Ochmann C, Schönberger T, Jürgens T, Geisler T, Schlosshauer B, Lunov O, Engelhardt S, Simmet T, Gawaz M.

Circulation. 2012 Feb 7;125(5):685-96. doi: 10.1161/CIRCULATIONAHA.111.070508. Epub 2012 Jan 5.

PMID:
22223428
21.

Inhibition of foam cell formation using a soluble CD68-Fc fusion protein.

Daub K, Siegel-Axel D, Schönberger T, Leder C, Seizer P, Müller K, Schaller M, Penz S, Menzel D, Büchele B, Bültmann A, Münch G, Lindemann S, Simmet T, Gawaz M.

J Mol Med (Berl). 2010 Sep;88(9):909-20. doi: 10.1007/s00109-010-0629-y. Epub 2010 May 8.

PMID:
20454888
22.

Modulating immune responses and inflammation.

Leder C, Ziegler M, Gawaz M.

Semin Thromb Hemost. 2010 Mar;36(2):219-22. doi: 10.1055/s-0030-1251507. Epub 2010 Apr 22. Review.

PMID:
20414838
23.

PD-1 regulates neural damage in oligodendroglia-induced inflammation.

Kroner A, Schwab N, Ip CW, Leder C, Nave KA, Mäurer M, Wiendl H, Martini R.

PLoS One. 2009;4(2):e4405. doi: 10.1371/journal.pone.0004405. Epub 2009 Feb 6. Erratum in: PLoS One. 2011;6(1). doi: 10.1371/annotation/51612e49-7bbe-4a84-b88d-fc5b7d79d853.

24.

A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols.

Lundberg K, Roos AK, Pavlenko M, Leder C, Wehrum D, Guevara-Patiño J, Andersen RS, Pisa P.

Vaccine. 2009 Mar 4;27(10):1557-65. doi: 10.1016/j.vaccine.2009.01.011. Epub 2009 Jan 24.

PMID:
19171173
25.

B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis.

Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H.

Eur J Immunol. 2008 Jun;38(6):1734-44. doi: 10.1002/eji.200738071.

26.

Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice.

Leder C, Schwab N, Ip CW, Kroner A, Nave KA, Dornmair K, Martini R, Wiendl H.

Mol Cell Neurosci. 2007 Nov;36(3):416-24. Epub 2007 Aug 15.

PMID:
17889554
27.

Priming of CD8+ T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice.

Pavlenko M, Leder C, Moreno S, Levitsky V, Pisa P.

Vaccine. 2007 Aug 21;25(34):6341-7. Epub 2007 Jun 29.

PMID:
17628235
28.

Modulation of T-effector function by imatinib at the level of cytokine secretion.

Leder C, Ortler S, Seggewiss R, Einsele H, Wiendl H.

Exp Hematol. 2007 Aug;35(8):1266-71. Epub 2007 Jun 8.

PMID:
17560008
29.

Expression of CD28-related costimulatory molecule and its ligand in inflammatory neuropathies.

Hu W, Janke A, Ortler S, Hartung HP, Leder C, Kieseier BC, Wiendl H.

Neurology. 2007 Jan 23;68(4):277-82.

PMID:
17242332
30.

Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes.

Ip CW, Kroner A, Bendszus M, Leder C, Kobsar I, Fischer S, Wiendl H, Nave KA, Martini R.

J Neurosci. 2006 Aug 2;26(31):8206-16.

31.

Estimating subglottal pressure using incomplete airflow interruption.

Jiang J, Leder C, Bichler A.

Laryngoscope. 2006 Jan;116(1):89-92.

PMID:
16481816
32.

Efficiency of HPV 16 L1/E7 DNA immunization: influence of cellular localization and capsid assembly.

Kuck D, Leder C, Kern A, Müller M, Piuko K, Gissmann L, Kleinschmidt JA.

Vaccine. 2006 Apr 5;24(15):2952-65. Epub 2005 Dec 29.

PMID:
16414157
33.

Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation.

Roos AK, Moreno S, Leder C, Pavlenko M, King A, Pisa P.

Mol Ther. 2006 Feb;13(2):320-7. Epub 2005 Sep 26.

34.

Plasmid DNA vaccines against cancer: cytotoxic T-lymphocyte induction against tumor antigens.

Pavlenko M, Leder C, Pisa P.

Expert Rev Vaccines. 2005 Jun;4(3):315-27. Review.

PMID:
16026247
35.

Comparison of PSA-specific CD8+ CTL responses and antitumor immunity generated by plasmid DNA vaccines encoding PSA-HSP chimeric proteins.

Pavlenko M, Roos AK, Leder C, Hansson LO, Kiessling R, Levitskaya E, Pisa P.

Cancer Immunol Immunother. 2004 Dec;53(12):1085-92.

PMID:
15696608
36.

Identification of an immunodominant H-2D(b)-restricted CTL epitope of human PSA.

Pavlenko M, Leder C, Roos AK, Levitsky V, Pisa P.

Prostate. 2005 Jun 15;64(1):50-9.

PMID:
15651071
37.
38.

Identification of a heparin-binding motif on adeno-associated virus type 2 capsids.

Kern A, Schmidt K, Leder C, Müller OJ, Wobus CE, Bettinger K, Von der Lieth CW, King JA, Kleinschmidt JA.

J Virol. 2003 Oct;77(20):11072-81.

39.

Influence of high-dose methotrexate therapy (HD-MTX) on glomerular and tubular kidney function.

Hempel L, Misselwitz J, Fleck C, Kentouche K, Leder C, Appenroth D, Rost M, Zintl F.

Med Pediatr Oncol. 2003 Jun;40(6):348-54.

PMID:
12692801
40.
41.

[Histomorphology after transmyocardial laser revascularization].

Krabatsch T, Schäper F, Tambeur L, Leder C, Thalmann U, Hetzer R.

Herz. 1997 Aug;22(4):205-10. German.

PMID:
9378454
42.

Histological findings after transmyocardial laser revascularization.

Krabatsch T, Schäper F, Leder C, Tülsner J, Thalmann U, Hetzer R.

J Card Surg. 1996 Sep-Oct;11(5):326-31.

PMID:
8969377

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