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Items: 1 to 50 of 56

1.

Potent repression of C-reactive protein (CRP) expression by the JAK1/2 inhibitor ruxolitinib in inflammatory human hepatocytes.

Febvre-James M, Lecureur V, Fardel O.

Inflamm Res. 2019 Oct 25. doi: 10.1007/s00011-019-01293-1. [Epub ahead of print]

PMID:
31654094
2.

Beyond silicosis, is the world failing on silica hazards?

Cavalin C, Lescoat A, Ballerie A, Belhomme N, Jégo P, Jouneau S, Lecureur V, Lederlin M, Paris C, Rosental PA.

Lancet Respir Med. 2019 Aug;7(8):649-650. doi: 10.1016/S2213-2600(19)30174-2. Epub 2019 May 17. No abstract available.

PMID:
31109828
3.

Alteration of human macrophage phenotypes by the anti-fibrotic drug nintedanib.

Bellamri N, Morzadec C, Joannes A, Lecureur V, Wollin L, Jouneau S, Vernhet L.

Int Immunopharmacol. 2019 Jul;72:112-123. doi: 10.1016/j.intimp.2019.03.061. Epub 2019 Apr 8.

PMID:
30974282
4.

Induction of multidrug resistance-associated protein 3 expression by diesel exhaust particle extract in human bronchial epithelial BEAS-2B cells.

Le Vée M, Bacle A, Jouan E, Lecureur V, Potin S, Fardel O.

Toxicol In Vitro. 2019 Aug;58:60-68. doi: 10.1016/j.tiv.2019.03.021. Epub 2019 Mar 19.

5.

An integrated functional and transcriptomic analysis reveals that repeated exposure to diesel exhaust induces sustained mitochondrial and cardiac dysfunctions.

Karoui A, Crochemore C, Mulder P, Preterre D, Cazier F, Dewaele D, Corbière C, Mekki M, Vendeville C, Richard V, Vaugeois JM, Fardel O, Sichel F, Lecureur V, Monteil C.

Environ Pollut. 2019 Mar;246:518-526. doi: 10.1016/j.envpol.2018.12.049. Epub 2018 Dec 17.

6.

A novel Staphylococcus aureus cis-trans type I toxin-antitoxin module with dual effects on bacteria and host cells.

Germain-Amiot N, Augagneur Y, Camberlein E, Nicolas I, Lecureur V, Rouillon A, Felden B.

Nucleic Acids Res. 2019 Feb 28;47(4):1759-1773. doi: 10.1093/nar/gky1257.

7.

Efferocytosis capacities of blood monocyte-derived macrophages in systemic sclerosis.

Ballerie A, Lescoat A, Augagneur Y, Lelong M, Morzadec C, Cazalets C, Jouneau S, Fardel O, Vernhet L, Jégo P, Lecureur V.

Immunol Cell Biol. 2019 Mar;97(3):340-347. doi: 10.1111/imcb.12217. Epub 2018 Dec 13.

8.

M1/M2 polarisation state of M-CSF blood-derived macrophages in systemic sclerosis.

Lescoat A, Ballerie A, Jouneau S, Fardel O, Vernhet L, Jego P, Lecureur V.

Ann Rheum Dis. 2019 Nov;78(11):e127. doi: 10.1136/annrheumdis-2018-214333. Epub 2018 Sep 29. No abstract available.

PMID:
30269049
9.

Long term exposure to environmental concentrations of diesel exhaust particles does not impact the phenotype of human bronchial epithelial cells.

Savary CC, Bellamri N, Morzadec C, Langouët S, Lecureur V, Vernhet L.

Toxicol In Vitro. 2018 Oct;52:154-160. doi: 10.1016/j.tiv.2018.06.014. Epub 2018 Jun 19.

10.

Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement.

Lescoat A, Ballerie A, Augagneur Y, Morzadec C, Vernhet L, Fardel O, Jégo P, Jouneau S, Lecureur V.

Int J Mol Sci. 2018 Mar 17;19(3). pii: E894. doi: 10.3390/ijms19030894.

11.

M-CSF and GM-CSF monocyte-derived macrophages in systemic sclerosis: the two sides of the same coin?

Lescoat A, Jégo P, Lecureur V.

Ann Rheum Dis. 2019 Mar;78(3):e19. doi: 10.1136/annrheumdis-2018-213112. Epub 2018 Feb 9. No abstract available.

PMID:
29439999
12.

Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats.

Douki T, Corbière C, Preterre D, Martin PJ, Lecureur V, André V, Landkocz Y, Pottier I, Keravec V, Fardel O, Moreira-Rebelo S, Pottier D, Vendeville C, Dionnet F, Gosset P, Billet S, Monteil C, Sichel F.

Environ Pollut. 2018 Apr;235:514-524. doi: 10.1016/j.envpol.2017.12.077. Epub 2018 Jan 8.

PMID:
29324381
13.

Repression of interferon β-regulated cytokines by the JAK1/2 inhibitor ruxolitinib in inflammatory human macrophages.

Febvre-James M, Lecureur V, Augagneur Y, Mayati A, Fardel O.

Int Immunopharmacol. 2018 Jan;54:354-365. doi: 10.1016/j.intimp.2017.11.032. Epub 2017 Dec 1.

PMID:
29202299
14.

Granulometry, microbial composition and biological activity of dusts collected in French dairy farms.

Pfister H, Morzadec C, Le Cann P, Madec L, Lecureur V, Chouvet M, Jouneau S, Vernhet L.

Environ Res. 2017 Oct;158:691-702. doi: 10.1016/j.envres.2017.07.025. Epub 2017 Jul 20.

PMID:
28735230
15.

CD16-positive circulating monocytes and fibrotic manifestations of systemic sclerosis.

Lescoat A, Lecureur V, Roussel M, Sunnaram BL, Ballerie A, Coiffier G, Jouneau S, Fardel O, Fest T, Jégo P.

Clin Rheumatol. 2017 Jul;36(7):1649-1654. doi: 10.1007/s10067-017-3597-6. Epub 2017 Mar 14.

PMID:
28293753
16.

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.

Le Vee M, Jouan E, Lecureur V, Fardel O.

Toxicol Appl Pharmacol. 2016 Jan 1;290:74-85. doi: 10.1016/j.taap.2015.11.014. Epub 2015 Nov 24.

17.

AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation.

Jaguin M, Fardel O, Lecureur V.

Toxicol Appl Pharmacol. 2015 Jun 15;285(3):170-8. doi: 10.1016/j.taap.2015.04.007. Epub 2015 Apr 17.

PMID:
25896968
18.

Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract.

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O.

PLoS One. 2015 Mar 24;10(3):e0121232. doi: 10.1371/journal.pone.0121232. eCollection 2015.

19.

Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.

Jaguin M, Fardel O, Lecureur V.

PLoS One. 2015 Feb 24;10(2):e0116560. doi: 10.1371/journal.pone.0116560. eCollection 2015.

20.

AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells.

Øvrevik J, Låg M, Lecureur V, Gilot D, Lagadic-Gossmann D, Refsnes M, Schwarze PE, Skuland T, Becher R, Holme JA.

Cell Commun Signal. 2014 Jul 24;12:48. doi: 10.1186/s12964-014-0048-8.

21.

Impaired functions of macrophage from cystic fibrosis patients: CD11b, TLR-5 decrease and sCD14, inflammatory cytokines increase.

Simonin-Le Jeune K, Le Jeune A, Jouneau S, Belleguic C, Roux PF, Jaguin M, Dimanche-Boitre MT, Lecureur V, Leclercq C, Desrues B, Brinchault G, Gangneux JP, Martin-Chouly C.

PLoS One. 2013 Sep 30;8(9):e75667. doi: 10.1371/journal.pone.0075667. eCollection 2013.

22.

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin.

Jaguin M, Houlbert N, Fardel O, Lecureur V.

Cell Immunol. 2013 Jan;281(1):51-61. doi: 10.1016/j.cellimm.2013.01.010. Epub 2013 Feb 4.

PMID:
23454681
23.

MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells.

Lecureur V, Arzel M, Ameziane S, Houlbert N, Le Vee M, Jouneau S, Fardel O.

Toxicology. 2012 Feb 6;292(1):13-22. doi: 10.1016/j.tox.2011.11.011. Epub 2011 Nov 28.

PMID:
22138297
24.

Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells.

Podechard N, Tekpli X, Catheline D, Holme JA, Rioux V, Legrand P, Rialland M, Fardel O, Lagadic-Gossmann D, Lecureur V.

Toxicol Lett. 2011 Oct 30;206(3):289-99. doi: 10.1016/j.toxlet.2011.07.024. Epub 2011 Aug 18.

PMID:
21872649
25.

Regulation of drug transporter expression by oncostatin M in human hepatocytes.

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O.

Biochem Pharmacol. 2011 Aug 1;82(3):304-11. doi: 10.1016/j.bcp.2011.04.017. Epub 2011 May 6.

26.

Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.

Asare N, Tekpli X, Rissel M, Solhaug A, Landvik N, Lecureur V, Podechard N, Brunborg G, Låg M, Lagadic-Gossmann D, Holme JA.

Mutagenesis. 2009 Nov;24(6):481-93. doi: 10.1093/mutage/gep032. Epub 2009 Aug 24.

PMID:
19703935
27.

Differential regulation of drug transporter expression by hepatocyte growth factor in primary human hepatocytes.

Le Vee M, Lecureur V, Moreau A, Stieger B, Fardel O.

Drug Metab Dispos. 2009 Nov;37(11):2228-35. doi: 10.1124/dmd.109.028035. Epub 2009 Aug 6.

PMID:
19661216
28.

Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene.

Podechard N, Fardel O, Corolleur M, Bernard M, Lecureur V.

Toxicol In Vitro. 2009 Sep;23(6):1139-44. doi: 10.1016/j.tiv.2009.05.011. Epub 2009 May 30.

PMID:
19486938
29.

NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons.

Podechard N, Le Ferrec E, Rebillard A, Fardel O, Lecureur V.

Cardiovasc Res. 2009 May 1;82(2):361-70. doi: 10.1093/cvr/cvp007. Epub 2009 Jan 8.

PMID:
19131362
30.

Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6.

Le Vee M, Lecureur V, Stieger B, Fardel O.

Drug Metab Dispos. 2009 Mar;37(3):685-93. doi: 10.1124/dmd.108.023630. Epub 2008 Dec 15.

PMID:
19074973
31.

Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.

Podechard N, Lecureur V, Le Ferrec E, Guenon I, Sparfel L, Gilot D, Gordon JR, Lagente V, Fardel O.

Toxicol Lett. 2008 Mar 15;177(2):130-7. doi: 10.1016/j.toxlet.2008.01.006. Epub 2008 Jan 19.

PMID:
18289803
32.

AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons.

Monteiro P, Gilot D, Le Ferrec E, Lecureur V, N'diaye M, Le Vee M, Podechard N, Pouponnot C, Fardel O.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):442-8. Epub 2007 Apr 26.

PMID:
17490615
33.

Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

N'Diaye M, Le Ferrec E, Lagadic-Gossmann D, Corre S, Gilot D, Lecureur V, Monteiro P, Rauch C, Galibert MD, Fardel O.

J Biol Chem. 2006 Jul 21;281(29):19906-15. Epub 2006 May 5.

34.

ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages.

Lecureur V, Ferrec EL, N'diaye M, Vee ML, Gardyn C, Gilot D, Fardel O.

FEBS Lett. 2005 Mar 28;579(9):1904-10.

35.

Alterations of intracellular pH homeostasis in apoptosis: origins and roles.

Lagadic-Gossmann D, Huc L, Lecureur V.

Cell Death Differ. 2004 Sep;11(9):953-61. Review.

36.

[Drug membrane transporters in the liver: regulation of their expression and activity].

Fardel O, Payen L, Sparfel L, Vernhet L, Lecureur V.

Ann Pharm Fr. 2002 Nov;60(6):380-5. French.

PMID:
12514503
37.

Potassium antimonyl tartrate induces caspase- and reactive oxygen species-dependent apoptosis in lymphoid tumoral cells.

Lecureur V, Le Thiec A, Le Meur A, Amiot L, Drenou B, Bernard M, Lamy T, Fauchet R, Fardel O.

Br J Haematol. 2002 Dec;119(3):608-15.

PMID:
12437633
38.

Potassium antimonyl tartrate induces reactive oxygen species-related apoptosis in human myeloid leukemic HL60 cells.

Lecureur V, Lagadic-Gossmann D, Fardel O.

Int J Oncol. 2002 May;20(5):1071-6.

PMID:
11956606
39.

Differentiation of the P-gp and MRP1 multidrug resistance systems by mobile lipid 1H-NMR spectroscopy and phosphatidylserine externalization.

Mannechez A, Collet B, Payen L, Lecureur V, Fardel O, Le Moyec L, de Certaines JD, Leray G.

Anticancer Res. 2001 Nov-Dec;21(6A):3915-9.

PMID:
11911269
40.

Regulation of biliary drug efflux pump expression by hormones and xenobiotics.

Fardel O, Payen L, Courtois A, Vernhet L, Lecureur V.

Toxicology. 2001 Oct 5;167(1):37-46. Review.

PMID:
11557128
41.

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD.

J Biol Chem. 2001 Oct 19;276(42):39411-8. Epub 2001 Aug 16.

42.

Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo.

Lecureur V, Thottassery JV, Sun D, Schuetz EG, Lahti J, Zambetti GP, Schuetz JD.

Oncogene. 2001 Jan 18;20(3):303-13.

43.

Expression and regulation of hepatic drug and bile acid transporters.

Lecureur V, Courtois A, Payen L, Verhnet L, Guillouzo A, Fardel O.

Toxicology. 2000 Nov 16;153(1-3):203-19. Review.

PMID:
11090958
44.

Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.

Lecureur V, Sun D, Hargrove P, Schuetz EG, Kim RB, Lan LB, Schuetz JD.

Mol Pharmacol. 2000 Jan;57(1):24-35.

PMID:
10617675
45.

Differential expression of the polyspecific drug transporter OCT1 in rat hepatocarcinoma cells.

Lecureur V, Guillouzo A, Fardel O.

Cancer Lett. 1998 Apr 24;126(2):227-33.

PMID:
9585071
46.

Induction of multidrug resistance gene expression in rat liver cells in response to acute treatment by the DNA-damaging agent methyl methanesulfonate.

Fardel O, Payen L, Courtois A, Lecureur V, Guillouzo A.

Biochem Biophys Res Commun. 1998 Apr 7;245(1):85-9.

PMID:
9535788
47.

Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment.

Fardel O, Lecureur V, Daval S, Corlu A, Guillouzo A.

Eur J Biochem. 1997 May 15;246(1):186-92.

48.

The P-glycoprotein multidrug transporter.

Fardel O, Lecureur V, Guillouzo A.

Gen Pharmacol. 1996 Dec;27(8):1283-91. Review.

PMID:
9304397
49.

Involvement of P-glycoprotein in an in vitro blood-brain barrier model.

Joly B, Lecureur V, Puozzo C, Guillouzo A, Fardel O.

Int J Oncol. 1996 Nov;9(5):1029-33.

PMID:
21541610
50.

Inhibition of P-glycoprotein activity in human leukemic cells by mifepristone.

Fardel O, Courtois A, Drenou B, Lamy T, Lecureur V, le Prisé PY, Fauchet R.

Anticancer Drugs. 1996 Aug;7(6):671-7.

PMID:
8913436

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