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Items: 1 to 50 of 75

1.

New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence.

Melo GD, Goyard S, Lecoeur H, Rouault E, Pescher P, Fiette L, Boissonnas A, Minoprio P, Lang T.

PLoS Negl Trop Dis. 2017 Sep 25;11(9):e0005924. doi: 10.1371/journal.pntd.0005924. eCollection 2017 Sep.

2.

Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis.

Caridha D, Parriot S, Hudson TH, Lang T, Ngundam F, Leed S, Sena J, Harris M, O'Neil M, Sciotti R, Read L, Lecoeur H, Hickman M, Grogl M.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02048-16. doi: 10.1128/AAC.02048-16. Print 2017 Apr.

3.

Imaging visceral leishmaniasis in real time with golden hamster model: Monitoring the parasite burden and hamster transcripts to further characterize the immunological responses of the host.

Rouault E, Lecoeur H, Meriem AB, Minoprio P, Goyard S, Lang T.

Parasitol Int. 2017 Feb;66(1):933-939. doi: 10.1016/j.parint.2016.10.020. Epub 2016 Oct 26.

PMID:
27794505
4.

Cross reactivity of S. aureus to murine cytokine assays: A source of discrepancy.

Javed N, Xue G, Lu A, Xing Y, Iwakura Y, Xiao H, Lecoeur H, Späth GF, Meng G.

Cytokine. 2016 May;81:101-8. doi: 10.1016/j.cyto.2016.03.007. Epub 2016 Mar 12.

PMID:
26978550
5.

A combined luciferase-expressing Leishmania imaging/RT-qPCR assay provides new insights into the sequential bilateral processes deployed in the ear pinna of C57BL/6 mice.

Giraud E, Lecoeur H, Rouault E, Goyard S, Milon G, Lang T.

Parasitol Int. 2014 Feb;63(1):245-53. doi: 10.1016/j.parint.2013.08.013. Epub 2013 Aug 31.

6.

Reprogramming neutral lipid metabolism in mouse dendritic leucocytes hosting live Leishmania amazonensis amastigotes.

Lecoeur H, Giraud E, Prévost MC, Milon G, Lang T.

PLoS Negl Trop Dis. 2013 Jun 13;7(6):e2276. doi: 10.1371/journal.pntd.0002276. Print 2013.

7.

Distinct transcriptional signatures of bone marrow-derived C57BL/6 and DBA/2 dendritic leucocytes hosting live Leishmania amazonensis amastigotes.

Giraud E, Lecoeur H, Soubigou G, Coppée JY, Milon G, Prina E, Lang T.

PLoS Negl Trop Dis. 2012;6(12):e1980. doi: 10.1371/journal.pntd.0001980. Epub 2012 Dec 13.

8.

HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase.

Lecoeur H, Borgne-Sanchez A, Chaloin O, El-Khoury R, Brabant M, Langonné A, Porceddu M, Brière JJ, Buron N, Rebouillat D, Péchoux C, Deniaud A, Brenner C, Briand JP, Muller S, Rustin P, Jacotot E.

Cell Death Dis. 2012 Mar 15;3:e282. doi: 10.1038/cddis.2012.21.

9.

A combined luciferase imaging and reverse transcription polymerase chain reaction assay for the study of Leishmania amastigote burden and correlated mouse tissue transcript fluctuations.

de La Llave E, Lecoeur H, Besse A, Milon G, Prina E, Lang T.

Cell Microbiol. 2011 Jan;13(1):81-91. doi: 10.1111/j.1462-5822.2010.01521.x. Epub 2010 Sep 16.

PMID:
20846338
10.

Early curative applications of the aminoglycoside WR279396 on an experimental Leishmania major-loaded cutaneous site do not impair the acquisition of immunity.

Lecoeur H, Buffet PA, Milon G, Lang T.

Antimicrob Agents Chemother. 2010 Mar;54(3):984-90. doi: 10.1128/AAC.01310-09. Epub 2009 Dec 28.

11.

Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression.

Lecoeur H, de La Llave E, Osorio Y Fortéa J, Goyard S, Kiefer-Biasizzo H, Balazuc AM, Milon G, Prina E, Lang T.

Microbes Infect. 2010 Jan;12(1):46-54. doi: 10.1016/j.micinf.2009.09.014. Epub 2009 Sep 26.

PMID:
19786115
12.

Imaging Leishmania development in their host cells.

Lang T, Lecoeur H, Prina E.

Trends Parasitol. 2009 Oct;25(10):464-73. doi: 10.1016/j.pt.2009.07.006. Epub 2009 Sep 4. Review.

PMID:
19734094
13.

A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice.

Brabant M, Baux L, Casimir R, Briand JP, Chaloin O, Porceddu M, Buron N, Chauvier D, Lassalle M, Lecoeur H, Langonné A, Dupont S, Déas O, Brenner C, Rebouillat D, Muller S, Borgne-Sanchez A, Jacotot E.

Apoptosis. 2009 Oct;14(10):1190-203. doi: 10.1007/s10495-009-0394-y.

PMID:
19693674
14.

Analysis of apoptotic pathways by multiparametric flow cytometry: application to HIV infection.

Lecoeur H, Melki MT, Saïdi H, Gougeon ML.

Methods Enzymol. 2008;442:51-82. doi: 10.1016/S0076-6879(08)01403-1.

PMID:
18662564
15.

Optimization of topical therapy for Leishmania major localized cutaneous leishmaniasis using a reliable C57BL/6 Model.

Lecoeur H, Buffet P, Morizot G, Goyard S, Guigon G, Milon G, Lang T.

PLoS Negl Trop Dis. 2007 Nov 28;1(2):e34.

16.

Unveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function.

Osorio y Fortéa J, Prina E, de La Llave E, Lecoeur H, Lang T, Milon G.

Immunol Rev. 2007 Oct;219:66-74. Review.

PMID:
17850482
17.

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.

Borgne-Sanchez A, Dupont S, Langonné A, Baux L, Lecoeur H, Chauvier D, Lassalle M, Déas O, Brière JJ, Brabant M, Roux P, Péchoux C, Briand JP, Hoebeke J, Deniaud A, Brenner C, Rustin P, Edelman L, Rebouillat D, Jacotot E.

Cell Death Differ. 2007 Mar;14(3):422-35. Epub 2006 Aug 4.

18.

Upstream control of apoptosis by caspase-2 in serum-deprived primary neurons.

Chauvier D, Lecoeur H, Langonné A, Borgne-Sanchez A, Mariani J, Martinou JC, Rebouillat D, Jacotot E.

Apoptosis. 2005 Dec;10(6):1243-59.

PMID:
16215683
19.

Reduction of antibiotic use in the community reduces the rate of colonization with penicillin G-nonsusceptible Streptococcus pneumoniae.

Guillemot D, Varon E, Bernède C, Weber P, Henriet L, Simon S, Laurent C, Lecoeur H, Carbon C.

Clin Infect Dis. 2005 Oct 1;41(7):930-8. Epub 2005 Aug 29.

PMID:
16142656
20.

The seroepidemiology of Bordetella pertussis infection in Western Europe.

Pebody RG, Gay NJ, Giammanco A, Baron S, Schellekens J, Tischer A, Olander RM, Andrews NJ, Edmunds WJ, Lecoeur H, Lévy-Bruhl D, Maple PA, de Melker H, Nardone A, Rota MC, Salmaso S, Conyn-van Spaendonck MA, Swidsinski S, Miller E.

Epidemiol Infect. 2005 Feb;133(1):159-71.

21.

Dynamic analysis of apoptosis in primary cortical neurons by fixed- and real-time cytofluorometry.

Lecoeur H, Chauvier D, Langonné A, Rebouillat D, Brugg B, Mariani J, Edelman L, Jacotot E.

Apoptosis. 2004 Mar;9(2):157-69.

PMID:
15004513
22.

Real-time flow cytometry analysis of permeability transition in isolated mitochondria.

Lecoeur H, Langonné A, Baux L, Rebouillat D, Rustin P, Prévost MC, Brenner C, Edelman L, Jacotot E.

Exp Cell Res. 2004 Mar 10;294(1):106-17.

PMID:
14980506
23.

A nonsecreted variant of interleukin-4 is associated with apoptosis: implication for the T helper-2 polarization in HIV infection.

Ledru E, Février M, Lecoeur H, Garcia S, Boullier S, Gougeon ML.

Blood. 2003 Apr 15;101(8):3102-5. Epub 2002 Dec 19.

PMID:
12515722
24.

Multiparametric flow cytometric analysis of biochemical and functional events associated with apoptosis and oncosis using the 7-aminoactinomycin D assay.

Lecoeur H, de Oliveira-Pinto LM, Gougeon ML.

J Immunol Methods. 2002 Jul 1;265(1-2):81-96. Review.

PMID:
12072180
25.

Nuclear apoptosis detection by flow cytometry: influence of endogenous endonucleases.

Lecoeur H.

Exp Cell Res. 2002 Jul 1;277(1):1-14. Review.

PMID:
12061813
27.

Lack of control of T cell apoptosis under HAART. Influence of therapy regimen in vivo and in vitro.

de Oliveira Pinto LM, Lecoeur H, Ledru E, Rapp C, Patey O, Gougeon ML.

AIDS. 2002 Feb 15;16(3):329-39.

PMID:
11834943
28.

The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver.

Terradillos O, de La Coste A, Pollicino T, Neuveut C, Sitterlin D, Lecoeur H, Gougeon ML, Kahn A, Buendia MA.

Oncogene. 2002 Jan 17;21(3):377-86.

29.

Clinical evaluation of the management of community-acquired pneumonia by general practitioners in France.

Fantin B, Aubert JP, Unger P, Lecoeur H, Carbon C.

Chest. 2001 Jul;120(1):185-92.

PMID:
11451836
30.

SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.

Chami M, Gozuacik D, Lagorce D, Brini M, Falson P, Peaucellier G, Pinton P, Lecoeur H, Gougeon ML, le Maire M, Rizzuto R, Bréchot C, Paterlini-Bréchot P.

J Cell Biol. 2001 Jun 11;153(6):1301-14.

31.

A novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity.

Lecoeur H, Février M, Garcia S, Rivière Y, Gougeon ML.

J Immunol Methods. 2001 Jul 1;253(1-2):177-87.

PMID:
11384679
33.

HIV, cytokines and programmed cell death. A subtle interplay.

Gougeon ML, Ledru E, Naora H, Bocchino M, Lecoeur H.

Ann N Y Acad Sci. 2000;926:30-45. Review.

PMID:
11193039
34.

The seroepidemiology of rubella in western Europe.

Pebody RG, Edmunds WJ, Conyn-van Spaendonck M, Olin P, Berbers G, Rebiere I, Lecoeur H, Crovari P, Davidkin I, Gabutti G, Gerike E, Giordano C, Hesketh L, Plesner AM, Raux M, Rota MC, Salmaso S, Tischer A, Valle M, Miller E.

Epidemiol Infect. 2000 Oct;125(2):347-57. Erratum in: Epidemiol Infect 2001 Apr;126(2):333.

35.

Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis.

Chami M, Gozuacik D, Saigo K, Capiod T, Falson P, Lecoeur H, Urashima T, Beckmann J, Gougeon ML, Claret M, le Maire M, Bréchot C, Paterlini-Bréchot P.

Oncogene. 2000 Jun 8;19(25):2877-86.

36.

Apoptosis and the CD95 system in HIV disease: impact of highly active anti-retroviral therapy (HAART).

Gougeon ML, Lecoeur H, Sasaki Y.

Immunol Lett. 1999 Mar;66(1-3):97-103.

PMID:
10203040
37.

T cell apoptosis in HIV infection: mechanisms and relevance for AIDS pathogenesis.

Gougeon ML, Ledru E, Lecoeur H, Garcia S.

Results Probl Cell Differ. 1998;24:233-48. Review. No abstract available.

PMID:
9949839
38.

Pro-apoptotic effect of the hepatitis B virus X gene.

Pollicino T, Terradillos O, Lecoeur H, Gougeon ML, Buendia MA.

Biomed Pharmacother. 1998;52(9):363-8.

PMID:
9856282
39.

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro.

Terradillos O, Pollicino T, Lecoeur H, Tripodi M, Gougeon ML, Tiollais P, Buendia MA.

Oncogene. 1998 Oct 22;17(16):2115-23.

41.
43.

Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods.

Lecoeur H, Ledru E, Prévost MC, Gougeon ML.

J Immunol Methods. 1997 Dec 1;209(2):111-23.

PMID:
9461328
44.

Low dosage and long treatment duration of beta-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae.

Guillemot D, Carbon C, Balkau B, Geslin P, Lecoeur H, Vauzelle-Kervroëdan F, Bouvenot G, Eschwége E.

JAMA. 1998 Feb 4;279(5):365-70.

PMID:
9459469
45.

Potential deleterious effect of anti-viral cytotoxic lymphocyte through the CD95 (FAS/APO-1)-mediated pathway during chronic HIV infection.

Garcia S, Fevrier M, Dadaglio G, Lecoeur H, Riviere Y, Gougeon ML.

Immunol Lett. 1997 Jun 1;57(1-3):53-8.

PMID:
9232425
46.

Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype.

Gougeon ML, Lecoeur H, Boudet F, Ledru E, Marzabal S, Boullier S, Roué R, Nagata S, Heeney J.

J Immunol. 1997 Mar 15;158(6):2964-76.

PMID:
9058836
48.

Peripheral V gamma 9/V delta 2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons.

Poccia F, Boullier S, Lecoeur H, Cochet M, Poquet Y, Colizzi V, Fournie JJ, Gougeon ML.

J Immunol. 1996 Jul 1;157(1):449-61.

PMID:
8683151
49.

Comparative analysis of apoptosis in HIV-infected humans and chimpanzees: relation with lymphocyte activation.

Gougeon ML, Lecoeur H, Heeney J, Boudet F.

Immunol Lett. 1996 Jun;51(1-2):75-81.

PMID:
8811348
50.

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