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Innate lymphoid cells in the upper airways: importance of CD117 and IL-1RI expression.
Van Crombruggen K, Taveirne S, Holtappels G, Leclercq G, Bachert C.
Eur Respir J. 2018 Dec 6;52(6). pii: 1800742. doi: 10.1183/13993003.00742-2018. Print 2018 Dec.
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[74-year-old man with a complex acromio-clavicular disjunction].
Juanos Cabanas J, Jennart H, Leclercq G, Zorman D.
Rev Med Brux. 2018;39(1):50-54. doi: 10.30637/2018.17-014. French.
Identifying Biomarkers of Wharton's Jelly Mesenchymal Stromal Cells Using a Dynamic Metabolic Model: The Cell Passage Effect.
Laflaquière B, Leclercq G, Choey C, Chen J, Peres S, Ito C, Jolicoeur M.
Metabolites. 2018 Feb 24;8(1). pii: E18. doi: 10.3390/metabo8010018.
Natural Anti-Estrogen Receptor Alpha Antibodies Able to Induce Estrogenic Responses in Breast Cancer Cells: Hypotheses Concerning Their Mechanisms of Action and Emergence.
Leclercq G.
Int J Mol Sci. 2018 Jan 30;19(2). pii: E411. doi: 10.3390/ijms19020411. Review.
Porcine NK cells display features associated with antigen-presenting cells.
De Pelsmaeker S, Devriendt B, Leclercq G, Favoreel HW.
J Leukoc Biol. 2018 Jan;103(1):129-140. doi: 10.1002/JLB.4A0417-163RR. Epub 2017 Dec 21.
Comparative analysis of the immune responses induced by native versus recombinant versions of the ASP-based vaccine against the bovine intestinal parasite Cooperia oncophora.
González-Hernández A, Borloo J, Peelaers I, Casaert S, Leclercq G, Claerebout E, Geldhof P.
Int J Parasitol. 2018 Jan;48(1):41-49. doi: 10.1016/j.ijpara.2017.07.002. Epub 2017 Aug 30.
The checkpoint for agonist selection precedes conventional selection in human thymus.
Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, Cheroutre H, Vandekerckhove B.
Sci Immunol. 2017 Feb 24;2(8). pii: eaah4232. doi: 10.1126/sciimmunol.aah4232.
ERE-dependent transcription and cell proliferation: Independency of these two processes mediated by the introduction of a sulfone function into the weak estrogen estrothiazine.
Jacquot Y, Spaggiari D, Schappler J, Lesniewska E, Rudaz S, Leclercq G.
Eur J Pharm Sci. 2017 Nov 15;109:169-181. doi: 10.1016/j.ejps.2017.07.026. Epub 2017 Jul 25.
A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties.
Van Acker A, Gronke K, Biswas A, Martens L, Saeys Y, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Plum J, Dunay IR, Diefenbach A, Leclercq G.
Cell Rep. 2017 May 16;19(7):1431-1443. doi: 10.1016/j.celrep.2017.04.068.
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B.
Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017.
Differential Effects of CORM-2 and CORM-401 in Murine Intestinal Epithelial MODE-K Cells under Oxidative Stress.
Babu D, Leclercq G, Motterlini R, Lefebvre RA.
Front Pharmacol. 2017 Feb 8;8:31. doi: 10.3389/fphar.2017.00031. eCollection 2017.
Sofosbuvir/ledipasvir and ribavirin tolerability and efficacy in pediatric liver transplant recipients.
Huysentruyt K, Stephenne X, Varma S, Scheers I, Leclercq G, Smets F, Sokal EM.
Liver Transpl. 2017 Apr;23(4):552-553. doi: 10.1002/lt.24692. No abstract available.
The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection.
Filtjens J, Coltel N, Cencig S, Taveirne S, Van Ammel E, Van Acker A, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Carlier Y, Truyens C, Leclercq G.
Front Immunol. 2016 Nov 10;7:472. eCollection 2016.
The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression.
Van Acker A, Louagie E, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Elewaut D, Taghon T, Vandekerckhove B, Plum J, Leclercq G.
Cancer Immunol Immunother. 2016 Nov;65(11):1365-1375. Epub 2016 Sep 1.
Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients.
Put K, Vandenhaute J, Avau A, van Nieuwenhuijze A, Brisse E, Dierckx T, Rutgeerts O, Garcia-Perez JE, Toelen J, Waer M, Leclercq G, Goris A, Van Weyenbergh J, Liston A, De Somer L, Wouters CH, Matthys P.
Arthritis Rheumatol. 2017 Jan;69(1):213-224. doi: 10.1002/art.39933.
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
Drennan MB, Govindarajan S, Verheugen E, Coquet JM, Staal J, McGuire C, Taghon T, Leclercq G, Beyaert R, van Loo G, Lambrecht BN, Elewaut D.
J Exp Med. 2016 Sep 19;213(10):1973-81. doi: 10.1084/jem.20151065. Epub 2016 Aug 22.
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours.
Filtjens J, Keirsse J, Van Ammel E, Taveirne S, Van Acker A, Kerre T, Taghon T, Vandekerckhove B, Plum J, Van Ginderachter JA, Leclercq G.
Sci Rep. 2016 Jul 29;6:30564. doi: 10.1038/srep30564.
Host protective ASP-based vaccine against the parasitic nematode Ostertagia ostertagi triggers NK cell activation and mixed IgG1-IgG2 response.
González-Hernández A, Van Coppernolle S, Borloo J, Van Meulder F, Paerewijck O, Peelaers I, Leclercq G, Claerebout E, Geldhof P.
Sci Rep. 2016 Jul 11;6:29496. doi: 10.1038/srep29496.
ERα dimerization: a key factor for the weak estrogenic activity of an ERα modulator unable to compete with estradiol in binding assays.
Leclercq G, Laïos I, Elie-Caille C, Leiber D, Laurent G, Lesniewska E, Tanfin Z, Jacquot Y.
J Recept Signal Transduct Res. 2017 Apr;37(2):149-166. doi: 10.1080/10799893.2016.1203940. Epub 2016 Jul 12.
Difference in replication of low-passage MCMV HaNa1 in BALB/c, C57BL/6 and NOD mice and role of different branches of immunity in susceptibility.
Xiang J, Zhang S, Leclercq G, Nauwynck H.
Virus Res. 2016 Aug 2;221:38-46. doi: 10.1016/j.virusres.2016.05.006. Epub 2016 May 10.
Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition.
Alari-Pahissa E, Grandclément C, Jeevan-Raj B, Leclercq G, Veillette A, Held W.
PLoS One. 2016 Apr 7;11(4):e0153236. doi: 10.1371/journal.pone.0153236. eCollection 2016.
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate.
Van de Walle I, Dolens AC, Durinck K, De Mulder K, Van Loocke W, Damle S, Waegemans E, De Medts J, Velghe I, De Smedt M, Vandekerckhove B, Kerre T, Plum J, Leclercq G, Rothenberg EV, Van Vlierberghe P, Speleman F, Taghon T.
Nat Commun. 2016 Apr 6;7:11171. doi: 10.1038/ncomms11171.
[Interest of non invasive navigation in total knee arthroplasty].
Zorman D, Leclercq G, Cabanas JJ, Jennart H.
Rev Med Brux. 2015 May-Jun;36(3):158-60. French.
The sequence Pro295-Thr311 of the hinge region of oestrogen receptor α is involved in ERK1/2 activation via GPR30 in leiomyoma cells.
Leiber D, Burlina F, Byrne C, Robin P, Piesse C, Gonzalez L, Leclercq G, Tanfin Z, Jacquot Y.
Biochem J. 2015 Nov 15;472(1):97-109. doi: 10.1042/BJ20150744. Epub 2015 Sep 14.
Antioxidant potential of CORM-A1 and resveratrol during TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells.
Babu D, Leclercq G, Goossens V, Remijsen Q, Vandenabeele P, Motterlini R, Lefebvre RA.
Toxicol Appl Pharmacol. 2015 Oct 15;288(2):161-78. doi: 10.1016/j.taap.2015.07.007. Epub 2015 Jul 14.
Mitochondria and NADPH oxidases are the major sources of TNF-α/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells.
Babu D, Leclercq G, Goossens V, Vanden Berghe T, Van Hamme E, Vandenabeele P, Lefebvre RA.
Cell Signal. 2015 Jun;27(6):1141-58. doi: 10.1016/j.cellsig.2015.02.019. Epub 2015 Feb 26.
Computations underlying the visuomotor transformation for smooth pursuit eye movements.
Murdison TS, Leclercq G, Lefèvre P, Blohm G.
J Neurophysiol. 2015 Mar 1;113(5):1377-99. doi: 10.1152/jn.00273.2014. Epub 2014 Dec 4.
Notch3 activation is sufficient but not required for inducing human T-lineage specification.
Waegemans E, Van de Walle I, De Medts J, De Smedt M, Kerre T, Vandekerckhove B, Leclercq G, Wang T, Plum J, Taghon T.
J Immunol. 2014 Dec 15;193(12):5997-6004. doi: 10.4049/jimmunol.1400764. Epub 2014 Nov 7.
In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis.
Vanhee S, De Mulder K, Van Caeneghem Y, Verstichel G, Van Roy N, Menten B, Velghe I, Philippé J, De Bleser D, Lambrecht BN, Taghon T, Leclercq G, Kerre T, Vandekerckhove B.
Haematologica. 2015 Feb;100(2):157-66. doi: 10.3324/haematol.2014.112144. Epub 2014 Nov 7.
Ly49E expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases.
Van Acker A, Filtjens J, Van Welden S, Taveirne S, Van Ammel E, Vanhees M, Devisscher L, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G.
PLoS One. 2014 Oct 13;9(10):e110015. doi: 10.1371/journal.pone.0110015. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0124464.
Spray-dried polyelectrolyte microparticles in oral antigen delivery: stability, biocompatibility, and cellular uptake.
De Smet R, Verschuere S, Allais L, Leclercq G, Dierendonck M, De Geest BG, Van Driessche I, Demoor T, Cuvelier CA.
Biomacromolecules. 2014 Jun 9;15(6):2301-9. doi: 10.1021/bm5005367. Epub 2014 May 14.
Environmental contamination, product contamination and workers exposure using a robotic system for antineoplastic drug preparation.
Sessink PJ, Leclercq GM, Wouters DM, Halbardier L, Hammad C, Kassoul N.
J Oncol Pharm Pract. 2015 Apr;21(2):118-27. doi: 10.1177/1078155214522840. Epub 2014 Feb 23.
Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development.
Filtjens J, Foquet L, Taveirne S, Van Ammel E, Vanhees M, Van Acker A, Kerre T, Taghon T, Vandekerckhove B, Plum J, Van den Steen PE, Leclercq G.
PLoS One. 2014 Jan 30;9(1):e87463. doi: 10.1371/journal.pone.0087463. eCollection 2014.
Systemic juvenile idiopathic arthritis-like syndrome in mice following stimulation of the immune system with Freund's complete adjuvant: regulation by interferon-γ.
Avau A, Mitera T, Put S, Put K, Brisse E, Filtjens J, Uyttenhove C, Van Snick J, Liston A, Leclercq G, Billiau AD, Wouters CH, Matthys P.
Arthritis Rheumatol. 2014 May;66(5):1340-51. doi: 10.1002/art.38359.
Education of murine NK cells requires both cis and trans recognition of MHC class I molecules.
Bessoles S, Angelov GS, Back J, Leclercq G, Vivier E, Held W.
J Immunol. 2013 Nov 15;191(10):5044-51. doi: 10.4049/jimmunol.1301971. Epub 2013 Oct 4.
In vitro generation of mature, naive antigen-specific CD8(+) T cells with a single T-cell receptor by agonist selection.
Snauwaert S, Verstichel G, Bonte S, Goetgeluk G, Vanhee S, Van Caeneghem Y, De Mulder K, Heirman C, Stauss H, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Thielemans K, Kerre T, Vandekerckhove B.
Leukemia. 2014 Apr;28(4):830-41. doi: 10.1038/leu.2013.285. Epub 2013 Oct 4.
β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination.
De Smet R, Demoor T, Verschuere S, Dullaers M, Ostroff GR, Leclercq G, Allais L, Pilette C, Dierendonck M, De Geest BG, Cuvelier CA.
J Control Release. 2013 Dec 28;172(3):671-8. doi: 10.1016/j.jconrel.2013.09.007. Epub 2013 Sep 14.
Accounting for direction and speed of eye motion in planning visually guided manual tracking.
Leclercq G, Blohm G, Lefèvre P.
J Neurophysiol. 2013 Oct;110(8):1945-57. doi: 10.1152/jn.00130.2013. Epub 2013 Aug 7.
Identification of polyproline II regions derived from the proline-rich nuclear receptor coactivators PNRC and PNRC2: new insights for ERα coactivator interactions.
Byrne C, Miclet E, Broutin I, Gallo D, Pelekanou V, Kampa M, Castanas E, Leclercq G, Jacquot Y.
Chirality. 2013 Oct;25(10):628-42. doi: 10.1002/chir.22188. Epub 2013 Aug 8.
Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.
Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T.
J Exp Med. 2013 Apr 8;210(4):683-97. doi: 10.1084/jem.20121798. Epub 2013 Mar 25.
Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function.
Filtjens J, Taveirne S, Van Acker A, Van Ammel E, Vanhees M, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G.
J Leukoc Biol. 2013 May;93(5):699-711. doi: 10.1189/jlb.0812378. Epub 2013 Mar 8.
Whole transcriptome analysis of the ERα synthetic fragment P295-T311 (ERα17p) identifies specific ERα-isoform (ERα, ERα36)-dependent and -independent actions in breast cancer cells.
Notas G, Kampa M, Pelekanou V, Troullinaki M, Jacquot Y, Leclercq G, Castanas E.
Mol Oncol. 2013 Jun;7(3):595-610. doi: 10.1016/j.molonc.2013.02.012. Epub 2013 Feb 20.
3D kinematics using dual quaternions: theory and applications in neuroscience.
Leclercq G, Lefèvre P, Blohm G.
Front Behav Neurosci. 2013 Feb 20;7:7. doi: 10.3389/fnbeh.2013.00007. eCollection 2013.
Differential Ly49e expression pathways in resting versus TCR-activated intraepithelial γδ T cells.
Van Den Broeck T, Van Ammel E, Delforche M, Taveirne S, Kerre T, Vandekerckhove B, Taghon T, Plum J, Leclercq G.
J Immunol. 2013 Mar 1;190(5):1982-90. doi: 10.4049/jimmunol.1200354. Epub 2013 Jan 21.
Interactions of isoflavones and other plant derived estrogens with estrogen receptors for prevention and treatment of breast cancer-considerations concerning related efficacy and safety.
Leclercq G, Jacquot Y.
J Steroid Biochem Mol Biol. 2014 Jan;139:237-44. doi: 10.1016/j.jsbmb.2012.12.010. Epub 2012 Dec 27. Review.
Electronic effects of 11β substituted 17β-estradiol derivatives and instrumental effects on the relative gas phase acidity.
Bourgoin-Voillard S, Fournier F, Afonso C, Zins EL, Jacquot Y, Pèpe C, Leclercq G, Tabet JC.
J Am Soc Mass Spectrom. 2012 Dec;23(12):2167-77. doi: 10.1007/s13361-012-0486-8. Epub 2012 Oct 2.
IL-15 augments TCR-induced CD4+ T cell expansion in vitro by inhibiting the suppressive function of CD25 High CD4+ T cells.
Van Belle TL, Dooms H, Boonefaes T, Wei XQ, Leclercq G, Grooten J.
PLoS One. 2012;7(9):e45299. doi: 10.1371/journal.pone.0045299. Epub 2012 Sep 20.
Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C.
J Neurosci. 2012 Jul 18;32(29):9805-16.
TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells.
Babu D, Soenen SJ, Raemdonck K, Leclercq G, De Backer O, Motterlini R, Lefebvre RA.
Curr Pharm Des. 2012;18(28):4414-25.
Accurate planning of manual tracking requires a 3D visuomotor transformation of velocity signals.
J Vis. 2012 May 25;12(5):6. doi: 10.1167/12.5.6.
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