Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57

1.

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes.

Chekkat N, Lombardo CM, Seguin C, Lechner MC, Dufour F, Nominé Y, De Giorgi M, Frisch B, Micheau O, Guichard G, Altschuh D, Fournel S.

Oncotarget. 2018 Feb 17;9(21):15566-15578. doi: 10.18632/oncotarget.24526. eCollection 2018 Mar 20.

2.

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels.

Beyrath J, Chekkat N, Smulski CR, Lombardo CM, Lechner MC, Seguin C, Decossas M, Spanedda MV, Frisch B, Guichard G, Fournel S.

Oncotarget. 2016 Oct 4;7(40):64942-64956. doi: 10.18632/oncotarget.10508.

3.

Thioether analogues of disulfide-bridged cyclic peptides targeting death receptor 5: conformational analysis, dimerisation and consequences for receptor activation.

Pulka-Ziach K, Pavet V, Chekkat N, Estieu-Gionnet K, Rohac R, Lechner MC, Smulski CR, Zeder-Lutz G, Altschuh D, Gronemeyer H, Fournel S, Odaert B, Guichard G.

Chembiochem. 2015 Jan 19;16(2):293-301. doi: 10.1002/cbic.201402485. Epub 2014 Dec 8.

PMID:
25487639
4.

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.

Pavet V, Beyrath J, Pardin C, Morizot A, Lechner MC, Briand JP, Wendland M, Maison W, Fournel S, Micheau O, Guichard G, Gronemeyer H.

Cancer Res. 2010 Feb 1;70(3):1101-10. doi: 10.1158/0008-5472.CAN-09-2889. Epub 2010 Jan 26.

5.

GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum.

Castro-Caldas M, Neves Carvalho A, Peixeiro I, Rodrigues E, Lechner MC, Gama MJ.

J Mol Neurosci. 2009 Jun;38(2):114-27. doi: 10.1007/s12031-008-9141-z. Epub 2008 Sep 16.

PMID:
18792812
6.

Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors.

Milagre I, Nunes MJ, Gama MJ, Silva RF, Pascussi JM, Lechner MC, Rodrigues E.

J Neurochem. 2008 Jul;106(2):835-49. doi: 10.1111/j.1471-4159.2008.05442.x. Epub 2008 Apr 28. Erratum in: J Neurochem. 2008 Nov;107(4):1168.

7.

Lobular neoplasia at percutaneous breast biopsy: variables associated with carcinoma at surgical excision.

Brem RF, Lechner MC, Jackman RJ, Rapelyea JA, Evans WP, Philpotts LE, Hargreaves J, Wasden S.

AJR Am J Roentgenol. 2008 Mar;190(3):637-41. doi: 10.2214/AJR.07.2768.

PMID:
18287433
8.

tert-Butyl 3-oxo-2-oxa-5-aza-bicyclo-[2.2.1]heptane-5-carboxyl-ate.

Lechner MC, Aubert E, Guichard G, Didierjean C.

Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 30;64(Pt 10):o2039. doi: 10.1107/S1600536808030651.

9.

Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease.

Vilar R, Coelho H, Rodrigues E, Gama MJ, Rivera I, Taioli E, Lechner MC.

Eur J Neurol. 2007 Feb;14(2):156-61.

PMID:
17250723
10.

Multicenter evaluation of a new ultrasound-guided biopsy device: Improved ergonomics, sampling and rebiopsy rates.

Duchesne N, Parker SH, Lechner MC, Gittleman MA, Kusnick CA, Elvecrog EE, Kaske TI, Gizienski TA.

Breast J. 2007 Jan-Feb;13(1):36-43.

PMID:
17214791
11.

Adding in vivo quantitative 1H MR spectroscopy to improve diagnostic accuracy of breast MR imaging: preliminary results of observer performance study at 4.0 T.

Meisamy S, Bolan PJ, Baker EH, Pollema MG, Le CT, Kelcz F, Lechner MC, Luikens BA, Carlson RA, Brandt KR, Amrami KK, Nelson MT, Everson LI, Emory TH, Tuttle TM, Yee D, Garwood M.

Radiology. 2005 Aug;236(2):465-75.

PMID:
16040903
12.

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls.

Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Katoh T, Kihara M, Ono-Kihara M, Kim H, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, London S, Manni JJ, Maugard CM, Morgan GJ, Morita S, Nazar-Stewart V, Kristensen VN, Oda Y, Parl FF, Peters WH, Rannug A, Rebbeck T, Pinto LF, Risch A, Romkes M, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnett D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Zheng W, Pedotti P, Taioli E.

Int J Cancer. 2004 Jun 10;110(2):266-70.

13.

Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study.

Smits KM, Gaspari L, Weijenberg MP, Dolzan V, Golka K, Roemer HC, Nedelcheva Kristensen V, Lechner MC, Mehling GI, Seidegard J, Strange RC, Taioli E.

Biomarkers. 2003 May-Aug;8(3-4):299-310.

PMID:
12944179
14.

Two CCAAT/enhancer binding protein sites in the cytochrome P4503A1 locus. Potential role in the glucocorticoid response.

Rodrigues E, Vilarem MJ, Ribeiro V, Maurel P, Lechner MC.

Eur J Biochem. 2003 Feb;270(3):556-64.

15.

Percutaneous core needle biopsy of radial scars of the breast: when is excision necessary?

Brenner RJ, Jackman RJ, Parker SH, Evans WP 3rd, Philpotts L, Deutch BM, Lechner MC, Lehrer D, Sylvan P, Hunt R, Adler SJ, Forcier N.

AJR Am J Roentgenol. 2002 Nov;179(5):1179-84.

PMID:
12388495
16.

Metabolic gene polymorphism frequencies in control populations.

Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, Bouchardy C, Breskvar K, Brockmoller J, Cascorbi I, Clapper ML, Coutelle C, Daly A, Dell'Omo M, Dolzan V, Dresler CM, Fryer A, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Kihara M, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, van Lieshout EM, London S, Manni JJ, Maugard CM, Morita S, Nazar-Stewart V, Noda K, Oda Y, Parl FF, Pastorelli R, Persson I, Peters WH, Rannug A, Rebbeck T, Risch A, Roelandt L, Romkes M, Ryberg D, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnet D, Strange RC, Stücker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Taioli E.

Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1239-48.

17.

Glycerol increases the yield and activity of human phenylalanine hydroxylase mutant enzymes produced in a prokaryotic expression system.

Leandro P, Lechner MC, Tavares de Almeida I, Konecki D.

Mol Genet Metab. 2001 Jun;73(2):173-8.

PMID:
11386853
18.

Stereotactic breast biopsy of nonpalpable lesions: determinants of ductal carcinoma in situ underestimation rates.

Jackman RJ, Burbank F, Parker SH, Evans WP 3rd, Lechner MC, Richardson TR, Smid AA, Borofsky HB, Lee CH, Goldstein HM, Schilling KJ, Wray AB, Brem RF, Helbich TH, Lehrer DE, Adler SJ.

Radiology. 2001 Feb;218(2):497-502.

PMID:
11161168
19.

The V388M mutation results in a kinetic variant form of phenylalanine hydroxylase.

Leandro P, Rivera I, Lechner MC, de Almeida IT, Konecki D.

Mol Genet Metab. 2000 Mar;69(3):204-12.

PMID:
10767175
20.

The correlation of genotype and phenotype in Portuguese hyperphenylalaninemic patients.

Rivera I, Cabral A, Almeida M, Leandro P, Carmona C, Eusébio F, Tasso T, Vilarinho L, Martins E, Lechner MC, de Almeida IT, Konecki DS, Lichter-Konecki U.

Mol Genet Metab. 2000 Mar;69(3):195-203.

PMID:
10767174
21.

Cerebral hemorrhage and apoE.

Garcia C, Pinho e Melo T, Rocha L, Lechner MC.

J Neurol. 1999 Sep;246(9):830-4.

PMID:
10525983
22.

N-acetyltransferase (NAT2) genotype and susceptibility of sporadic Alzheimer's disease.

Rocha L, Garcia C, de Mendonça A, Gil JP, Bishop DT, Lechner MC.

Pharmacogenetics. 1999 Feb;9(1):9-15.

PMID:
10208637
23.
24.

Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer.

Cristóvão L, Lechner MC, Fidalgo P, Leitão CN, Mira FC, Rueff J.

Br J Cancer. 1998 May;77(10):1628-32.

25.

Age of onset in patients with Alzheimer's disease with different apoE genotypes.

do Couto FS, de Mendonça A, Garcia C, Rocha L, Lechner MC.

J Neurol Neurosurg Psychiatry. 1998 Jun;64(6):817. No abstract available.

26.

Population genetics of hyperphenylalaninaemia resulting from phenylalanine hydroxylase deficiency in Portugal.

Rivera I, Leandro P, Lichter-Konecki U, Tavares de Almeida I, Lechner MC.

J Med Genet. 1998 Apr;35(4):301-4.

28.

Identification of a functional glucocorticoid response element in the CYP3A1/IGC2 gene.

Pereira TM, Carlstedt-Duke J, Lechner MC, Gustafsson JA.

DNA Cell Biol. 1998 Jan;17(1):39-49.

PMID:
9468221
29.

Developmental changes in the constitutive and inducible expression of cytochrome P450 3A2.

Wright MC, Edwards RJ, Pimenta M, Ribeiro V, Ratra GS, Lechner MC, Paine AJ.

Biochem Pharmacol. 1997 Oct 1;54(7):841-6.

PMID:
9353139
30.

Allele frequency of CYP2C19 in a Portuguese population.

Ruas JL, Lechner MC.

Pharmacogenetics. 1997 Aug;7(4):333-5. No abstract available.

PMID:
9295062
31.

Atypical ductal hyperplasia diagnosed at stereotactic breast biopsy: improved reliability with 14-gauge, directional, vacuum-assisted biopsy.

Jackman RJ, Burbank F, Parker SH, Evans WP 3rd, Lechner MC, Richardson TR, Tocino I, Wray AB.

Radiology. 1997 Aug;204(2):485-8.

PMID:
9240540
32.

Relative frequency of IVS10nt546 mutation in a Portuguese phenylketonuric population.

Rivera I, Leandro P, Lichter-Konecki U, de Almeida IT, Lechner MC.

Hum Mutat. 1997;9(3):272-3. No abstract available.

PMID:
9090531
33.

Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid.

Wright MC, Wang XJ, Pimenta M, Ribeiro V, Paine AJ, Lechner MC.

Mol Pharmacol. 1996 Oct;50(4):856-63.

PMID:
8863830
34.

Critical amino-terminal segments in insertion of rat liver cytochrome P450 3A1 into the endoplasmic reticulum membrane.

Van den Broek PJ, Barroso M, Lechner MC.

Experientia. 1996 Sep 15;52(9):851-5.

PMID:
8841512
35.
36.

Mutation analysis of phenylketonuria in south and central Portugal: prevalence of V388M mutation.

Leandro P, Rivera I, Ribeiro V, de Almeida IT, da Silveira C, Lechner MC.

Hum Mutat. 1995;6(2):192-4. No abstract available.

PMID:
7581408
37.

Aging effects on hepatic NADPH cytochrome P450 reductase, CYP2B1&2, and polymeric immunoglobulin receptor mRNAs in male Fischer 344 rats.

van Bezooijen RL, Wang RK, Lechner MC, Schmucker DL.

Exp Gerontol. 1994 Mar-Apr;29(2):187-95.

PMID:
7517894
38.

Nonpalpable breast lesions: correlation of stereotaxic large-core needle biopsy and surgical biopsy results.

Elvecrog EL, Lechner MC, Nelson MT.

Radiology. 1993 Aug;188(2):453-5.

PMID:
8327696
39.
41.

Modulation of P-450 IIC7 and IIIA1,2 mRNA in pre-neoplastic liver. Effect of promotion by phenobarbital.

Lechner MC, Barroso M, Decloitre F, Lafarge-Frayssinet C, Ouldelhkim M, Frayssinet C.

Biochim Biophys Acta. 1990 Oct 23;1087(2):157-64.

PMID:
1699606
42.

The steroid antagonist RU38486 is metabolized by the liver microsomal P450 mono-oxygenases.

Chasserot-Golaz S, Ribeiro V, Genot G, Lechner MC, Beck G.

Biochem Biophys Res Commun. 1990 Mar 30;167(3):1271-8.

PMID:
2322272
43.

[Modulation of mRNAs P450 and hepatocarcinogenesis promotion].

Lechner MC, Ribeiro VL, Henrique D, Barroso M, Cravino MM.

Bull Cancer. 1990;77(5):509-14. French.

PMID:
2400826
44.

Effect of rat developmental stage at initiation on the expression of biochemical markers during liver tumor promotion.

Decloître F, Lafarge-Frayssinet C, Barroso M, Lechner MC, Ouldelhkim M, Frayssinet C.

Tumour Biol. 1990;11(6):295-305.

PMID:
1700861
45.

Expression of a constitutive form of cytochrome P450 during rat-liver development and sexual maturation.

Barroso M, Dargouge O, Lechner MC.

Eur J Biochem. 1988 Mar 1;172(2):363-9.

46.

Phenobarbital-mediated modulation of gene expression in rat liver. Analysis of cDNA clones.

Lechner MC, Sinogas C, Osório-Almeida ML, Freire MT, Chaumet-Riffaud P, Frain M, Sala-Trepat JM.

Eur J Biochem. 1987 Mar 2;163(2):231-8.

48.

Induction of alpha 2u globulin mRNA by phenobarbital in rat liver: characterization of a cDNA clone.

Osorio-Almeida ML, Sinogas C, Ludovice M, Lechner MC.

Biochem Biophys Res Commun. 1986 Feb 13;134(3):1182-9.

PMID:
2418834
50.

In vitro biosynthesis of liver cytochrome P450 mature peptide sub-unit by translation of isolated poly(A)+ mRNA from normal and phenobarbital induced rats.

Lechner MC, Freire MT, Groner B.

Biochem Biophys Res Commun. 1979 Sep 27;90(2):531-6. No abstract available.

PMID:
508320

Supplemental Content

Loading ...
Support Center