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Items: 1 to 50 of 99

1.

Gingers and Their Purified Components as Cancer Chemopreventative Agents.

Lechner JF, Stoner GD.

Molecules. 2019 Aug 7;24(16). pii: E2859. doi: 10.3390/molecules24162859. Review.

2.

Red Beetroot and Betalains as Cancer Chemopreventative Agents.

Lechner JF, Stoner GD.

Molecules. 2019 Apr 23;24(8). pii: E1602. doi: 10.3390/molecules24081602. Review.

3.

Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles.

Pan P, Skaer CW, Wang HT, Stirdivant SM, Young MR, Oshima K, Stoner GD, Lechner JF, Huang YW, Wang LS.

Carcinogenesis. 2015 Oct;36(10):1245-53. doi: 10.1093/carcin/bgv117. Epub 2015 Aug 5.

4.

Beneficial Regulation of Metabolic Profiles by Black Raspberries in Human Colorectal Cancer Patients.

Pan P, Skaer CW, Stirdivant SM, Young MR, Stoner GD, Lechner JF, Huang YW, Wang LS.

Cancer Prev Res (Phila). 2015 Aug;8(8):743-50. doi: 10.1158/1940-6207.CAPR-15-0065. Epub 2015 Jun 8.

5.

Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue.

Wang LS, Kuo CT, Huang TH, Yearsley M, Oshima K, Stoner GD, Yu J, Lechner JF, Huang YW.

Cancer Prev Res (Phila). 2013 Dec;6(12):1317-27. doi: 10.1158/1940-6207.CAPR-13-0077. Epub 2013 Oct 15.

6.

Gene-Diet Interactions on Colorectal Cancer Risk.

Wang LS, Kuo CT, Huang YW, Stoner GD, Lechner JF.

Curr Nutr Rep. 2012 Jul 10;1:132-141. eCollection 2012. Review.

7.

Drinking water with red beetroot food color antagonizes esophageal carcinogenesis in N-nitrosomethylbenzylamine-treated rats.

Lechner JF, Wang LS, Rocha CM, Larue B, Henry C, McIntyre CM, Riedl KM, Schwartz SJ, Stoner GD.

J Med Food. 2010 Jun;13(3):733-9. doi: 10.1089/jmf.2008.0280.

8.

Anthocyanins in black raspberries prevent esophageal tumors in rats.

Wang LS, Hecht SS, Carmella SG, Yu N, Larue B, Henry C, McIntyre C, Rocha C, Lechner JF, Stoner GD.

Cancer Prev Res (Phila). 2009 Jan;2(1):84-93. doi: 10.1158/1940-6207.CAPR-08-0155.

9.

Effects of a black raspberry diet on gene expression in the rat esophagus.

Lechner JF, Reen RK, Dombkowski AA, Cukovic D, Salagrama S, Wang LS, Stoner GD.

Nutr Cancer. 2008;60 Suppl 1:61-9. doi: 10.1080/01635580802393118.

PMID:
19003582
10.

Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate.

Stoner GD, Dombkowski AA, Reen RK, Cukovic D, Salagrama S, Wang LS, Lechner JF.

Cancer Res. 2008 Aug 1;68(15):6460-7. doi: 10.1158/0008-5472.CAN-08-0146.

11.

Cancer prevention with freeze-dried berries and berry components.

Stoner GD, Wang LS, Zikri N, Chen T, Hecht SS, Huang C, Sardo C, Lechner JF.

Semin Cancer Biol. 2007 Oct;17(5):403-10. Epub 2007 May 10. Review.

12.

Human lung cancer cells and tissues partially recapitulate the homeobox gene expression profile of embryonic lung.

Lechner JF, Wang Y, Siddiq F, Fugaro JM, Wali A, Lonardo F, Willey JC, Harris CC, Pass HI.

Lung Cancer. 2002 Jul;37(1):41-7.

PMID:
12057866
13.

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

Belinsky SA, Palmisano WA, Gilliland FD, Crooks LA, Divine KK, Winters SA, Grimes MJ, Harms HJ, Tellez CS, Smith TM, Moots PP, Lechner JF, Stidley CA, Crowell RE.

Cancer Res. 2002 Apr 15;62(8):2370-7.

14.

Reproducible gene expression measurement among multiple laboratories obtained in a blinded study using standardized RT (StaRT)-PCR.

Crawford EL, Peters GJ, Noordhuis P, Rots MG, Vondracek M, Grafström RC, Lieuallen K, Lennon G, Zahorchak RJ, Georgeson MJ, Wali A, Lechner JF, Fan PS, Kahaleh MB, Khuder SA, Warner KA, Weaver DA, Willey JC.

Mol Diagn. 2001 Dec;6(4):217-25.

PMID:
11774186
15.

Human papillomavirus type 16 is an important infectious factor in the high incidence of esophageal cancer in Anyang area of China.

Li T, Lu ZM, Chen KN, Guo M, Xing HP, Mei Q, Yang HH, Lechner JF, Ke Y.

Carcinogenesis. 2001 Jun;22(6):929-34.

PMID:
11375901
16.

Reduced DNA-dependent protein kinase activity is associated with lung cancer.

Auckley DH, Crowell RE, Heaphy ER, Stidley CA, Lechner JF, Gilliland FD, Belinsky SA.

Carcinogenesis. 2001 May;22(5):723-7.

PMID:
11323390
17.

Perspective: cell differentiation theory may advance early detection of and therapy for lung cancer.

Lechner JF, Fugaro JM, Wong Y, Pass HI, Harris CC, Belinsky SA.

Radiat Res. 2001 Jan;155(1 Pt 2):235-238.

PMID:
11121240
18.

A simple method for generating full length cDNA from low abundance partial genomic clones.

Wang Y, Fugaro JM, Siddiq F, Goparaju CM, Lonardo F, Wali A, Lechner JF, Pass HI.

BMC Mol Biol. 2000;1:2. Epub 2000 Nov 16.

19.

Frequency of trisomy 20 in nonmalignant bronchial epithelium from lung cancer patients and cancer-free former uranium miners and smokers.

Neft RE, Crowell RE, Gilliland FD, Murphy MM, Lane JL, Harms H, Coons T, Heaphy E, Belinsky SA, Lechner JF.

Cancer Epidemiol Biomarkers Prev. 1998 Nov;7(11):1051-4.

20.

Carcinogenic responses of transgenic heterozygous p53 knockout mice to inhaled 239PuO2 or metallic beryllium.

Finch GL, March TH, Hahn FF, Barr EB, Belinsky SA, Hoover MD, Lechner JF, Nikula KJ, Hobbs CH.

Toxicol Pathol. 1998 Jul-Aug;26(4):484-91.

PMID:
9715507
21.

Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells.

Kennedy CH, Cueto R, Belinsky SA, Lechner JF, Pryor WA.

FEBS Lett. 1998 Jun 5;429(1):17-20.

22.

A canine model of familial mammary gland neoplasia.

Schafer KA, Kelly G, Schrader R, Griffith WC, Muggenburg BA, Tierney LA, Lechner JF, Janovitz EB, Hahn FF.

Vet Pathol. 1998 May;35(3):168-77.

PMID:
9598580
23.

Individuals at high risk for lung cancer have airway epithelial cells with chromosome aberrations frequently found in lung tumor cells.

Lechner JF, Neft RE, Gilliland FD, Crowell RE, Auckley DH, Temes RT, Belinsky SA.

In Vivo. 1998 Jan-Feb;12(1):23-6.

PMID:
9575422
24.

Oncogenes and tumor-suppressor genes in mesothelioma--a synopsis.

Lechner JF, Tesfaigzi J, Gerwin BI.

Environ Health Perspect. 1997 Sep;105 Suppl 5:1061-7. Review.

25.

Concurrent fluorescence in situ hybridization and immunocytochemistry for the detection of chromosome aberrations in exfoliated bronchial epithelial cells.

Neft RE, Murphy MM, Tierney LA, Belinsky SA, Anderson M, Saccomanno G, Michels R, Timm S, Gilliland FD, Crowell RE, Lechner JF.

Acta Cytol. 1997 Nov-Dec;41(6):1769-73.

PMID:
9390139
26.

Molecular identification of individuals at high risk for lung cancer.

Lechner JF, Neft RE, Gilliland FD, Crowell RE, Belinsky SA.

Radiat Oncol Investig. 1997;5(3):103-5.

PMID:
9303064
27.

Radon and lung carcinogenesis: mutability of p53 codons 249 and 250 to 238Pu alpha-particles in human bronchial epithelial cells.

Hussain SP, Kennedy CH, Amstad P, Lui H, Lechner JF, Harris CC.

Carcinogenesis. 1997 Jan;18(1):121-5.

PMID:
9054598
28.

Chromosomal changes and progressive tumorigenesis of human bronchial epithelial cell lines.

Ohnuki Y, Reddel RR, Bates SE, Lehman TA, Lechner JF, Harris CC.

Cancer Genet Cytogenet. 1996 Dec;92(2):99-110.

PMID:
8976365
29.
30.

Detection of trisomy 7 in nonmalignant bronchial epithelium from lung cancer patients and individuals at risk for lung cancer.

Crowell RE, Gilliland FD, Temes RT, Harms HJ, Neft RE, Heaphy E, Auckley DH, Crooks LA, Jordan SW, Samet JM, Lechner JF, Belinsky SA.

Cancer Epidemiol Biomarkers Prev. 1996 Aug;5(8):631-7.

31.

Induction of genomic instability in normal human bronchial epithelial cells by 238Pu alpha-particles.

Kennedy CH, Mitchell CE, Fukushima NH, Neft RE, Lechner JF.

Carcinogenesis. 1996 Aug;17(8):1671-6.

PMID:
8761424
32.

Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse.

Finch GL, Nikula KJ, Belinsky SA, Barr EB, Stoner GD, Lechner JF.

Cancer Lett. 1996 Feb 6;99(2):161-7.

PMID:
8616820
33.
34.

An improved method for the isolation of type II and Clara cells from mice.

Belinsky SA, Lechner JF, Johnson NF.

In Vitro Cell Dev Biol Anim. 1995 May;31(5):361-6.

PMID:
7543342
35.

Detection and quantitation of mutant K-ras codon 12 restriction fragments by capillary electrophoresis.

Mitchell CE, Belinsky SA, Lechner JF.

Anal Biochem. 1995 Jan 1;224(1):148-53.

PMID:
7710062
36.

Alpha-particle-induced p53 protein expression in a rat lung epithelial cell strain.

Hickman AW, Jaramillo RJ, Lechner JF, Johnson NF.

Cancer Res. 1994 Nov 15;54(22):5797-800.

37.

Development of tumorigenicity in simian virus 40-immortalized human bronchial epithelial cell lines.

Reddel RR, Salghetti SE, Willey JC, Ohnuki Y, Ke Y, Gerwin BI, Lechner JF, Harris CC.

Cancer Res. 1993 Mar 1;53(5):985-91.

38.

Tumorigenic conversion of human mesothelial cells as a consequence of platelet-derived growth factor-A chain overexpression.

Van der Meeren A, Seddon MB, Betsholtz CA, Lechner JF, Gerwin BI.

Am J Respir Cell Mol Biol. 1993 Feb;8(2):214-21.

PMID:
8427711
39.

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.

Gerwin BI, Spillare E, Forrester K, Lehman TA, Kispert J, Welsh JA, Pfeifer AM, Lechner JF, Baker SJ, Vogelstein B, et al.

Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2759-63.

40.

TGF-beta 1 modulation of urokinase and PAI-1 expression in human bronchial epithelial cells.

Gerwin BI, Keski-Oja J, Seddon M, Lechner JF, Harris CC.

Am J Physiol. 1990 Oct;259(4 Pt 1):L262-9.

PMID:
2221087
41.
42.

Differential effects of cigarette smoke condensate and its fractions on cultured normal and malignant human bronchial epithelial cells.

Miyashita M, Willey JC, Sasajima K, Lechner JF, LaVoie EJ, Hoffmann D, Smith M, Trump BF, Harris CC.

Exp Pathol. 1990;38(1):19-29.

PMID:
2328782
43.

Transformation of human neonatal prostate epithelial cells by strontium phosphate transfection with a plasmid containing SV40 early region genes.

Kaighn ME, Reddel RR, Lechner JF, Peehl DM, Camalier RF, Brash DE, Saffiotti U, Harris CC.

Cancer Res. 1989 Jun 1;49(11):3050-6.

44.

Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma.

Ke Y, Reddel RR, Gerwin BI, Reddel HK, Somers AN, McMenamin MG, LaVeck MA, Stahel RA, Lechner JF, Harris CC.

Am J Pathol. 1989 May;134(5):979-91.

45.

Differential responses to growth factors by normal human mesothelial cultures from individual donors.

Lechner JF, LaVeck MA, Gerwin BI, Matis EA.

J Cell Physiol. 1989 May;139(2):295-300.

PMID:
2497107
46.

Control of growth and squamous differentiation in normal human bronchial epithelial cells by chemical and biological modifiers and transferred genes.

Pfeifer AM, Lechner JF, Masui T, Reddel RR, Mark GE, Harris CC.

Environ Health Perspect. 1989 Mar;80:209-20.

48.

Replicative cultures of adult human and rhesus monkey liver epithelial cells.

Lechner JF, Cole KE, Reddel RR, Anderson L, Harris CC.

Cancer Detect Prev. 1989;14(2):239-44.

PMID:
2620309
49.

Effects of palytoxin or ouabain on growth and squamous differentiation of human bronchial epithelial cells in vitro.

Bonnard C, Lechner JF, Gerwin BI, Fujiki H, Harris CC.

Carcinogenesis. 1988 Dec;9(12):2245-9.

PMID:
2903801
50.

Dissimilar peptide growth factors can induce normal human mesothelial cell multiplication.

Laveck MA, Somers AN, Moore LL, Gerwin BI, Lechner JF.

In Vitro Cell Dev Biol. 1988 Nov;24(11):1077-84.

PMID:
2461356

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