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Gingers and Their Purified Components as Cancer Chemopreventative Agents.

Lechner JF, Stoner GD.

Molecules. 2019 Aug 7;24(16). pii: E2859. doi: 10.3390/molecules24162859. Review.


Purple: A Computational Workflow for Strategic Selection of Peptides for Viral Diagnostics Using MS-Based Targeted Proteomics.

Lechner J, Hartkopf F, Hiort P, Nitsche A, Grossegesse M, Doellinger J, Renard BY, Muth T.

Viruses. 2019 Jun 8;11(6). pii: E536. doi: 10.3390/v11060536.


Sustained intraocular vascular endothelial growth factor neutralisation does not affect retinal and choroidal vasculature in Ins2Akita diabetic mice.

Lechner J, Hombrebueno JR, Pedrini E, Chen M, Xu H.

Diab Vasc Dis Res. 2019 Sep;16(5):440-449. doi: 10.1177/1479164119843092. Epub 2019 Apr 26.


Red Beetroot and Betalains as Cancer Chemopreventative Agents.

Lechner JF, Stoner GD.

Molecules. 2019 Apr 23;24(8). pii: E1602. doi: 10.3390/molecules24081602. Review.


Osteoimmunology of tumor necrosis factor-alpha, IL-6, and RANTES/CCL5: a review of known and poorly understood inflammatory patterns in osteonecrosis.

Lechner J, Rudi T, von Baehr V.

Clin Cosmet Investig Dent. 2018 Nov 9;10:251-262. doi: 10.2147/CCIDE.S184498. eCollection 2018. Review.


Titanium implants and silent inflammation in jawbone-a critical interplay of dissolved titanium particles and cytokines TNF-α and RANTES/CCL5 on overall health?

Lechner J, Noumbissi S, von Baehr V.

EPMA J. 2018 Jun 8;9(3):331-343. doi: 10.1007/s13167-018-0138-6. eCollection 2018 Sep.


Reticulocytosis in non-anaemic cats and dogs.

Fuchs J, Moritz A, Grußendorf E, Lechner J, Neuerer F, Nickel R, Rieker T, Schwedes C, DeNicola DB, Russell J, Bauer N.

J Small Anim Pract. 2018 Mar 30. doi: 10.1111/jsap.12831. [Epub ahead of print]


Unattached kinetochores drive their own capturing by sequestering a CLASP.

Kolenda C, Ortiz J, Pelzl M, Norell S, Schmeiser V, Lechner J.

Nat Commun. 2018 Feb 28;9(1):886. doi: 10.1038/s41467-018-03108-z.


Aseptic-avascular osteonecrosis: local "silent inflammation" in the jawbone and RANTES/CCL5 overexpression.

Lechner J, Schuett S, von Baehr V.

Clin Cosmet Investig Dent. 2017 Nov 9;9:99-109. doi: 10.2147/CCIDE.S149545. eCollection 2017.


Evaluation of reticulocyte hemoglobin content (RET-He) in the diagnosis of iron-deficient erythropoiesis in dogs.

Fuchs J, Moritz A, Grußendorf E, Lechner J, Neuerer F, Nickel R, Rieker T, Schwedes C, DeNicola DB, Russell J, Bauer N.

Vet Clin Pathol. 2017 Dec;46(4):558-568. doi: 10.1111/vcp.12547. Epub 2017 Oct 9.


Impact of Rantes from jawbone on Chronic Fatigue Syndrome.

Lechner J, Huesker K, Von Baehr V.

J Biol Regul Homeost Agents. 2017 Apr-Jun;31(2):321-327.


Canine reticulocyte hemoglobin content (RET-He) in different types of iron-deficient erythropoiesis.

Fuchs J, Moritz A, Grußendorf E, Lechner J, Neuerer F, Nickel R, Rieker T, Schwedes C, DeNicola DB, Russell J, Bauer N.

Vet Clin Pathol. 2017 Sep;46(3):422-429. doi: 10.1111/vcp.12499. Epub 2017 May 16.


Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides.

de Cogan F, Hill LJ, Lynch A, Morgan-Warren PJ, Lechner J, Berwick MR, Peacock AFA, Chen M, Scott RAH, Xu H, Logan A.

Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2578-2590. doi: 10.1167/iovs.16-20072.


The pathology associated with diabetic retinopathy.

Lechner J, O'Leary OE, Stitt AW.

Vision Res. 2017 Oct;139:7-14. doi: 10.1016/j.visres.2017.04.003. Epub 2017 Apr 29. Review.


Peripheral blood mononuclear cells from neovascular age-related macular degeneration patients produce higher levels of chemokines CCL2 (MCP-1) and CXCL8 (IL-8).

Lechner J, Chen M, Hogg RE, Toth L, Silvestri G, Chakravarthy U, Xu H.

J Neuroinflammation. 2017 Feb 23;14(1):42. doi: 10.1186/s12974-017-0820-y.


Efficacy against nematode infections and safety of afoxolaner plus milbemycin oxime chewable tablets in domestic dogs under field conditions in Europe.

Rehbein S, Knaus M, Mallouk Y, Breiltgens T, Brianti E, Capári B, Dantas-Torres F, Gau M, Joachim A, Kaulfuß KH, Kirkova Z, Lechner J, Mihalca AD, Mirabito R, Petkevičius S, Rapti D, Shukullari E, Sedeilhan M, Dollhofer D, Kley K, Lebon W, Visser M, Jeannin P.

Parasitol Res. 2017 Jan;116(1):259-269. Epub 2016 Oct 22.


Technology and tuberculosis control: the OUT-TB Web experience.

Guthrie JL, Alexander DC, Marchand-Austin A, Lam K, Whelan M, Lee B, Furness C, Rea E, Stuart R, Lechner J, Varia M, McLean J, Jamieson FB.

J Am Med Inform Assoc. 2017 Apr 1;24(e1):e136-e142. doi: 10.1093/jamia/ocw130.


Sex Differences in Renal Proximal Tubular Cell Homeostasis.

Seppi T, Prajczer S, Dörler MM, Eiter O, Hekl D, Nevinny-Stickel M, Skvortsova I, Gstraunthaler G, Lukas P, Lechner J.

J Am Soc Nephrol. 2016 Oct;27(10):3051-3062. Epub 2016 Apr 28.


STAT3 Activation in Circulating Monocytes Contributes to Neovascular Age-Related Macular Degeneration.

Chen M, Lechner J, Zhao J, Toth L, Hogg R, Silvestri G, Kissenpfennig A, Chakravarthy U, Xu H.

Curr Mol Med. 2016;16(4):412-23.


Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration: Complement activation in AMD.

Lechner J, Chen M, Hogg RE, Toth L, Silvestri G, Chakravarthy U, Xu H.

Immun Ageing. 2016 Feb 16;13:4. doi: 10.1186/s12979-016-0060-5. eCollection 2016.


Alterations in Circulating Immune Cells in Neovascular Age-Related Macular Degeneration.

Lechner J, Chen M, Hogg RE, Toth L, Silvestri G, Chakravarthy U, Xu H.

Sci Rep. 2015 Nov 17;5:16754. doi: 10.1038/srep16754.


Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles.

Pan P, Skaer CW, Wang HT, Stirdivant SM, Young MR, Oshima K, Stoner GD, Lechner JF, Huang YW, Wang LS.

Carcinogenesis. 2015 Oct;36(10):1245-53. doi: 10.1093/carcin/bgv117. Epub 2015 Aug 5.


Peripheral Neuropathic Facial/Trigeminal Pain and RANTES/CCL5 in Jawbone Cavitation.

Lechner J, von Baehr V.

Evid Based Complement Alternat Med. 2015;2015:582520. doi: 10.1155/2015/582520. Epub 2015 Jun 11.


Beneficial Regulation of Metabolic Profiles by Black Raspberries in Human Colorectal Cancer Patients.

Pan P, Skaer CW, Stirdivant SM, Young MR, Stoner GD, Lechner JF, Huang YW, Wang LS.

Cancer Prev Res (Phila). 2015 Aug;8(8):743-50. doi: 10.1158/1940-6207.CAPR-15-0065. Epub 2015 Jun 8.


Stimulation of proinflammatory cytokines by volatile sulfur compounds in endodontically treated teeth.

Lechner J, von Baehr V.

Int J Gen Med. 2015 Mar 10;8:109-18. doi: 10.2147/IJGM.S77693. eCollection 2015.


Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.

Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O'Brien C, McKnight AJ, Willoughby CE.

Genet Med. 2015 Apr;17(4):279-84. doi: 10.1038/gim.2014.121. Epub 2014 Sep 18.


Validation of dental X-ray by cytokine RANTES - comparison of X-ray findings with cytokine overexpression in jawbone.

Lechner J.

Clin Cosmet Investig Dent. 2014 Aug 21;6:71-9. doi: 10.2147/CCIDE.S69807. eCollection 2014.


Hyperactivated Signaling Pathways of Chemokine RANTES/CCL5 in Osteopathies of Jawbone in Breast Cancer Patients-Case Report and Research.

Lechner J, von Baehr V.

Breast Cancer (Auckl). 2014 May 21;8:89-96. doi: 10.4137/BCBCR.S15119. eCollection 2014.


Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus.

Lechner J, Porter LF, Rice A, Vitart V, Armstrong DJ, Schorderet DF, Munier FL, Wright AF, Inglehearn CF, Black GC, Simpson DA, Manson F, Willoughby CE.

Hum Mol Genet. 2014 Oct 15;23(20):5527-35. doi: 10.1093/hmg/ddu253. Epub 2014 Jun 3.


Evaluation of the Performance of a Novel Five-Level A1c Cellular Linearity Calibration Verification Kit.

Das K, Wigginton SM, Lechner JM.

J Diabetes Sci Technol. 2014 Jan;8(1):194-195. Epub 2014 Jan 1. No abstract available.


A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules.

Funk C, Schmeiser V, Ortiz J, Lechner J.

J Cell Biol. 2014 May 26;205(4):555-71. doi: 10.1083/jcb.201310018.


Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue.

Wang LS, Kuo CT, Huang TH, Yearsley M, Oshima K, Stoner GD, Yu J, Lechner JF, Huang YW.

Cancer Prev Res (Phila). 2013 Dec;6(12):1317-27. doi: 10.1158/1940-6207.CAPR-13-0077. Epub 2013 Oct 15.


A new blood collection device minimizes cellular DNA release during sample storage and shipping when compared to a standard device.

Norton SE, Luna KK, Lechner JM, Qin J, Fernando MR.

J Clin Lab Anal. 2013 Jul;27(4):305-11. doi: 10.1002/jcla.21603.


Mutational analysis of MIR184 in sporadic keratoconus and myopia.

Lechner J, Bae HA, Guduric-Fuchs J, Rice A, Govindarajan G, Siddiqui S, Abi Farraj L, Yip SP, Yap M, Das M, Souzeau E, Coster D, Mills RA, Lindsay R, Phillips T, Mitchell P, Ali M, Inglehearn CF, Sundaresan P, Craig JE, Simpson DA, Burdon KP, Willoughby CE.

Invest Ophthalmol Vis Sci. 2013 Aug 5;54(8):5266-72. doi: 10.1167/iovs.13-12035.


A stabilizing reagent prevents cell-free DNA contamination by cellular DNA in plasma during blood sample storage and shipping as determined by digital PCR.

Norton SE, Lechner JM, Williams T, Fernando MR.

Clin Biochem. 2013 Oct;46(15):1561-5. doi: 10.1016/j.clinbiochem.2013.06.002. Epub 2013 Jun 13.


RANTES and fibroblast growth factor 2 in jawbone cavitations: triggers for systemic disease?

Lechner J, von Baehr V.

Int J Gen Med. 2013 Apr 22;6:277-90. doi: 10.2147/IJGM.S43852. Print 2013.


Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

Lechner J, Dash DP, Muszynska D, Hosseini M, Segev F, George S, Frazer DG, Moore JE, Kaye SB, Young T, Simpson DA, Churchill AJ, Héon E, Willoughby CE.

Invest Ophthalmol Vis Sci. 2013 May 3;54(5):3215-23. doi: 10.1167/iovs.13-11781.


WITHDRAWN: Compatibility of a blood collection tube that stabilizes cell-free DNA with a rapid fluorescence assay.

Fernando DS, Lechner JM, Norton SE, Qin J, Fernando MR.

Clin Biochem. 2012 Oct 27. pii: S0009-9120(12)00605-4. doi: 10.1016/j.clinbiochem.2012.10.027. [Epub ahead of print]


Stabilization of cell-free RNA in blood samples using a new collection device.

Fernando MR, Norton SE, Luna KK, Lechner JM, Qin J.

Clin Biochem. 2012 Nov;45(16-17):1497-502. doi: 10.1016/j.clinbiochem.2012.07.090. Epub 2012 Jul 20.


Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.

Steringer JP, Bleicken S, Andreas H, Zacherl S, Laussmann M, Temmerman K, Contreras FX, Bharat TA, Lechner J, Müller HM, Briggs JA, García-Sáez AJ, Nickel W.

J Biol Chem. 2012 Aug 10;287(33):27659-69. doi: 10.1074/jbc.M112.381939. Epub 2012 Jun 23.


ABCD(2) as a screening tool for cerebral infarction on stroke MRI?

Hotter BA, Lechner JM, Nolte CH, Audebert HJ, Malzahn U, Heuschmann PU, Fiebach JB, Jungehulsing GJ.

Eur Neurol. 2012;67(5):315-20. doi: 10.1159/000336267. Epub 2012 Apr 27.


Evaluation of the performance and stability of a novel A1c-cellular control.

Das K, Krzyzanowski GD, Wigginton SM, Lechner JM, Ryan WL.

J Diabetes Sci Technol. 2012 Mar 1;6(2):483-5. No abstract available.


Gene-Diet Interactions on Colorectal Cancer Risk.

Wang LS, Kuo CT, Huang YW, Stoner GD, Lechner JF.

Curr Nutr Rep. 2012 Jul 10;1:132-141. eCollection 2012. Review.


Association of polymorphisms in the hepatocyte growth factor gene promoter with keratoconus.

Burdon KP, Macgregor S, Bykhovskaya Y, Javadiyan S, Li X, Laurie KJ, Muszynska D, Lindsay R, Lechner J, Haritunians T, Henders AK, Dash D, Siscovick D, Anand S, Aldave A, Coster DJ, Szczotka-Flynn L, Mills RA, Iyengar SK, Taylor KD, Phillips T, Montgomery GW, Rotter JI, Hewitt AW, Sharma S, Rabinowitz YS, Willoughby C, Craig JE.

Invest Ophthalmol Vis Sci. 2011 Oct 31;52(11):8514-9. doi: 10.1167/iovs.11-8261.


Mutation altering the miR-184 seed region causes familial keratoconus with cataract.

Hughes AE, Bradley DT, Campbell M, Lechner J, Dash DP, Simpson DA, Willoughby CE.

Am J Hum Genet. 2011 Nov 11;89(5):628-33. doi: 10.1016/j.ajhg.2011.09.014. Epub 2011 Oct 11.


Monitoring of the dynamics of epithelial dome formation using a novel culture chamber for long-term continuous live-cell imaging.

Lechner J, Hekl D, Gatt H, Voelp M, Seppi T.

Methods Mol Biol. 2011;763:169-78. doi: 10.1007/978-1-61779-191-8_11.


Drinking water with red beetroot food color antagonizes esophageal carcinogenesis in N-nitrosomethylbenzylamine-treated rats.

Lechner JF, Wang LS, Rocha CM, Larue B, Henry C, McIntyre CM, Riedl KM, Schwartz SJ, Stoner GD.

J Med Food. 2010 Jun;13(3):733-9. doi: 10.1089/jmf.2008.0280.

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