Sort by
Items per page

Send to

Choose Destination

Search results

Items: 45


Regulated spindle orientation buffers tissue growth in the epidermis.

Morrow A, Underwood J, Seldin L, Hinnant T, Lechler T.

Elife. 2019 Oct 2;8. pii: e48482. doi: 10.7554/eLife.48482.


Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.

Park J, Levic DS, Sumigray KD, Bagwell J, Eroglu O, Block CL, Eroglu C, Barry R, Lickwar CR, Rawls JF, Watts SA, Lechler T, Bagnat M.

Dev Cell. 2019 Oct 7;51(1):7-20.e6. doi: 10.1016/j.devcel.2019.08.001. Epub 2019 Aug 29.


Cellular Dynamics Driving Elongation of the Gut.

Sumigray K, Lechler T.

Dev Cell. 2018 Jul 16;46(2):127-128. doi: 10.1016/j.devcel.2018.06.027.


Genetically induced microtubule disruption in the mouse intestine impairs intracellular organization and transport.

Muroyama A, Terwilliger M, Dong B, Suh H, Lechler T.

Mol Biol Cell. 2018 Jul 1;29(13):1533-1541. doi: 10.1091/mbc.E18-01-0057. Epub 2018 May 9.


Morphogenesis and Compartmentalization of the Intestinal Crypt.

Sumigray KD, Terwilliger M, Lechler T.

Dev Cell. 2018 Apr 23;45(2):183-197.e5. doi: 10.1016/j.devcel.2018.03.024.


A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis.

Muroyama A, Lechler T.

Elife. 2017 Sep 4;6. pii: e29834. doi: 10.7554/eLife.29834.


Microtubule organization, dynamics and functions in differentiated cells.

Muroyama A, Lechler T.

Development. 2017 Sep 1;144(17):3012-3021. doi: 10.1242/dev.153171. Review.


Editorial overview: Cell architecture: Mechanisms and scales of cellular organization and decision making.

Lechler T, Carazo Salas RE.

Curr Opin Cell Biol. 2017 Feb;44:iv-v. doi: 10.1016/ No abstract available.


Divergent regulation of functionally distinct γ-tubulin complexes during differentiation.

Muroyama A, Seldin L, Lechler T.

J Cell Biol. 2016 Jun 20;213(6):679-92. doi: 10.1083/jcb.201601099. Epub 2016 Jun 13.


FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms.

Zhang X, Wu J, Luo S, Lechler T, Zhang JY.

Oncotarget. 2016 Jun 7;7(23):34371-83. doi: 10.18632/oncotarget.9110.


NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures.

Seldin L, Muroyama A, Lechler T.

Elife. 2016 Jan 14;5. pii: e12504. doi: 10.7554/eLife.12504.


Studying cell biology in the skin.

Morrow A, Lechler T.

Mol Biol Cell. 2015 Nov 15;26(23):4183-6. doi: 10.1091/mbc.E15-04-0246.


The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine.

Zhou K, Sumigray KD, Lechler T.

Mol Biol Cell. 2015 Jun 1;26(11):1995-2004. doi: 10.1091/mbc.E14-10-1481. Epub 2015 Apr 1.


Cell adhesion in epidermal development and barrier formation.

Sumigray KD, Lechler T.

Curr Top Dev Biol. 2015;112:383-414. doi: 10.1016/bs.ctdb.2014.11.027. Epub 2015 Feb 11. Review.


Arp2/3 complex function in the epidermis.

Lechler T.

Tissue Barriers. 2014 Aug 8;2(4):e944445. doi: 10.4161/21688362.2014.944445. eCollection 2014.


Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.

Sumigray K, Zhou K, Lechler T.

PLoS One. 2014 Jul 9;9(7):e101824. doi: 10.1371/journal.pone.0101824. eCollection 2014.


NuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions.

Seldin L, Poulson ND, Foote HP, Lechler T.

Mol Biol Cell. 2013 Dec;24(23):3651-62. doi: 10.1091/mbc.E13-05-0277. Epub 2013 Oct 9.


Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.

Zhou K, Muroyama A, Underwood J, Leylek R, Ray S, Soderling SH, Lechler T.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-9. doi: 10.1073/pnas.1308419110. Epub 2013 Sep 16.


FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes.

Foote HP, Sumigray KD, Lechler T.

PLoS One. 2013 Aug 19;8(8):e71491. doi: 10.1371/journal.pone.0071491. eCollection 2013.


beta-Catenin protects the epidermis from mechanical stresses.

Ray S, Foote HP, Lechler T.

J Cell Biol. 2013 Jul 8;202(1):45-52. doi: 10.1083/jcb.201212140. Epub 2013 Jul 1.


Noncentrosomal microtubules and type II myosins potentiate epidermal cell adhesion and barrier formation.

Sumigray KD, Foote HP, Lechler T.

J Cell Biol. 2012 Oct 29;199(3):513-25. doi: 10.1083/jcb.201206143. Epub 2012 Oct 22.


Polarity and stratification of the epidermis.

Muroyama A, Lechler T.

Semin Cell Dev Biol. 2012 Oct;23(8):890-6. doi: 10.1016/j.semcdb.2012.08.008. Epub 2012 Aug 31. Review.


Adherens junctions and stem cells.

Lechler T.

Subcell Biochem. 2012;60:359-77. doi: 10.1007/978-94-007-4186-7_15. Review.


Asymmetric cell divisions in the epidermis.

Poulson ND, Lechler T.

Int Rev Cell Mol Biol. 2012;295:199-232. doi: 10.1016/B978-0-12-394306-4.00012-5. Review.


Desmoplakin controls microvilli length but not cell adhesion or keratin organization in the intestinal epithelium.

Sumigray KD, Lechler T.

Mol Biol Cell. 2012 Mar;23(5):792-9. doi: 10.1091/mbc.E11-11-0923. Epub 2012 Jan 11.


Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.

Sumigray KD, Chen H, Lechler T.

J Cell Biol. 2011 Aug 22;194(4):631-42. doi: 10.1083/jcb.201104009. Epub 2011 Aug 15.


Regulation of asymmetric cell division in the epidermis.

Ray S, Lechler T.

Cell Div. 2011 Jun 6;6(1):12. doi: 10.1186/1747-1028-6-12.


Robust control of mitotic spindle orientation in the developing epidermis.

Poulson ND, Lechler T.

J Cell Biol. 2010 Nov 29;191(5):915-22. doi: 10.1083/jcb.201008001. Epub 2010 Nov 22.


Dissecting cell adhesion cross-talk with micropatterns.

Sumigray KD, Lechler T.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13199-200. doi: 10.1073/pnas.1008253107. Epub 2010 Jul 16. No abstract available.


Limiting lumens: a new role for Cdc42.

Lechler T.

J Cell Biol. 2008 Nov 17;183(4):575-7. doi: 10.1083/jcb.200809174. Epub 2008 Nov 10.


Asymmetric cell divisions promote stratification and differentiation of mammalian skin.

Lechler T, Fuchs E.

Nature. 2005 Sep 8;437(7056):275-80. Epub 2005 Aug 10.


Coordinating cytoskeletal tracks to polarize cellular movements.

Kodama A, Lechler T, Fuchs E.

J Cell Biol. 2004 Oct 25;167(2):203-7. Review.


Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses.

Tinkle CL, Lechler T, Pasolli HA, Fuchs E.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):552-7. Epub 2004 Jan 2.


Rapid de-localization of actin leading edge components with BDM treatment.

Yarrow JC, Lechler T, Li R, Mitchison TJ.

BMC Cell Biol. 2003 Jun 3;4:5.


Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro.

Soulard A, Lechler T, Spiridonov V, Shevchenko A, Shevchenko A, Li R, Winsor B.

Mol Cell Biol. 2002 Nov;22(22):7889-906.


A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast.

Lechler T, Jonsdottir GA, Klee SK, Pellman D, Li R.

J Cell Biol. 2001 Oct 15;155(2):261-70. Epub 2001 Oct 15.


Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization.

Lechler T, Shevchenko A, Li R.

J Cell Biol. 2000 Jan 24;148(2):363-73.


Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein.

Winter D, Lechler T, Li R.

Curr Biol. 1999 May 6;9(9):501-4.


Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta.

Xiao W, Lechler T, Chow BL, Fontanie T, Agustus M, Carter KC, Wei YF.

Carcinogenesis. 1998 May;19(5):945-9.


(Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen.

Dimmock JR, Puthucode RN, Smith JM, Hetherington M, Quail JW, Pugazhenthi U, Lechler T, Stables JP.

J Med Chem. 1996 Sep 27;39(20):3984-97.


Supplemental Content

Loading ...
Support Center