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Smooth Muscle Phenotype in Idiopathic Pulmonary Hypertension: Hyper-Proliferative but not Cancerous.

Perros F, Sentenac P, Boulate D, Manaud G, Kotsimbos T, Lecerf F, Lamrani L, Fadel E, Mercier O, Londono-Vallejo A, Humbert M, Eddahibi S.

Int J Mol Sci. 2019 Jul 22;20(14). pii: E3575. doi: 10.3390/ijms20143575.


ICAM-1 promotes the abnormal endothelial cell phenotype in chronic thromboembolic pulmonary hypertension.

Arthur Ataam J, Mercier O, Lamrani L, Amsallem M, Arthur Ataam J, Arthur Ataam S, Guihaire J, Lecerf F, Capuano V, Ghigna MR, Haddad F, Fadel E, Eddahibi S.

J Heart Lung Transplant. 2019 Sep;38(9):982-996. doi: 10.1016/j.healun.2019.06.010. Epub 2019 Jun 19.


Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension.

Hautefort A, Mendes-Ferreira P, Sabourin J, Manaud G, Bertero T, Rucker-Martin C, Riou M, Adão R, Manoury B, Lambert M, Boet A, Lecerf F, Domergue V, Brás-Silva C, Gomez AM, Montani D, Girerd B, Humbert M, Antigny F, Perros F.

Circulation. 2019 Feb 12;139(7):932-948. doi: 10.1161/CIRCULATIONAHA.118.033744.


Early outcomes of percutaneous pulmonary valve implantation using the Edwards SAPIEN 3 transcatheter heart valve system.

Hascoet S, Dalla Pozza R, Bentham J, Carere RG, Kanaan M, Ewert P, Biernacka EK, Kretschmar O, Deutsch C, Lecerf F, Lehner A, Kantzis M, Kurucova J, Thoenes M, Bramlage P, Haas NA.

EuroIntervention. 2019 Jan 20;14(13):1378-1385. doi: 10.4244/EIJ-D-18-01035.


T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

Sankhe S, Manousakidi S, Antigny F, Arthur Ataam J, Bentebbal S, Ruchon Y, Lecerf F, Sabourin J, Price L, Fadel E, Dorfmüller P, Eddahibi S, Humbert M, Perros F, Capuano V.

Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1631-1641. doi: 10.1016/j.bbamcr.2017.06.018. Epub 2017 Jun 24.


Long noncoding RNA repertoire in chicken liver and adipose tissue.

Muret K, Klopp C, Wucher V, Esquerré D, Legeai F, Lecerf F, Désert C, Boutin M, Jehl F, Acloque H, Giuffra E, Djebali S, Foissac S, Derrien T, Lagarrigue S.

Genet Sel Evol. 2017 Jan 10;49(1):6. doi: 10.1186/s12711-016-0275-0.


Abnormal pulmonary endothelial cells may underlie the enigmatic pathogenesis of chronic thromboembolic pulmonary hypertension.

Mercier O, Arthur Ataam J, Langer NB, Dorfmüller P, Lamrani L, Lecerf F, Decante B, Dartevelle P, Eddahibi S, Fadel E.

J Heart Lung Transplant. 2017 Mar;36(3):305-314. doi: 10.1016/j.healun.2016.08.012. Epub 2016 Aug 20.


Telomere Maintenance Is a Critical Determinant in the Physiopathology of Pulmonary Hypertension.

Izikki M, Hoang E, Draskovic I, Mercier O, Lecerf F, Lamrani L, Liu WY, Guignabert C, Fadel E, Dorfmuller P, Humbert M, Londoño-Vallejo A, Eddahibi S.

J Am Coll Cardiol. 2015 Oct 27;66(17):1942-3. doi: 10.1016/j.jacc.2015.08.869. No abstract available.


Nebivolol for improving endothelial dysfunction, pulmonary vascular remodeling, and right heart function in pulmonary hypertension.

Perros F, Ranchoux B, Izikki M, Bentebbal S, Happé C, Antigny F, Jourdon P, Dorfmüller P, Lecerf F, Fadel E, Simonneau G, Humbert M, Bogaard HJ, Eddahibi S.

J Am Coll Cardiol. 2015 Feb 24;65(7):668-80. doi: 10.1016/j.jacc.2014.11.050.


Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.

Roux PF, Boitard S, Blum Y, Parks B, Montagner A, Mouisel E, Djari A, Esquerré D, Désert C, Boutin M, Leroux S, Lecerf F, Le Bihan-Duval E, Klopp C, Servin B, Pitel F, Duclos MJ, Guillou H, Lusis AJ, Demeure O, Lagarrigue S.

G3 (Bethesda). 2015 Feb 3;5(4):517-29. doi: 10.1534/g3.115.016865.


Endothelial-to-mesenchymal transition in pulmonary hypertension.

Ranchoux B, Antigny F, Rucker-Martin C, Hautefort A, Péchoux C, Bogaard HJ, Dorfmüller P, Remy S, Lecerf F, Planté S, Chat S, Fadel E, Houssaini A, Anegon I, Adnot S, Simonneau G, Humbert M, Cohen-Kaminsky S, Perros F.

Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.


N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats.

Chaumais MC, Ranchoux B, Montani D, Dorfmüller P, Tu L, Lecerf F, Raymond N, Guignabert C, Price L, Simonneau G, Cohen-Kaminsky S, Humbert M, Perros F.

Respir Res. 2014 Jun 14;15:65. doi: 10.1186/1465-9921-15-65.


The beneficial effect of suramin on monocrotaline-induced pulmonary hypertension in rats.

Izikki M, Mercier O, Lecerf F, Guin LL, Hoang E, Dorfmüller P, Perros F, Humbert M, Simonneau G, Dartevelle P, Fadel E, Eddahibi S.

PLoS One. 2013 Oct 15;8(10):e77073. doi: 10.1371/journal.pone.0077073. eCollection 2013.


The GAG database: a new resource to gather genomic annotation cross-references.

Obadia T, Sallou O, Ouedraogo M, Guernec G, Lecerf F.

Gene. 2013 Sep 25;527(2):503-9. doi: 10.1016/j.gene.2013.06.063. Epub 2013 Jul 16.


Limited RNA editing in exons of mouse liver and adipose.

Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ.

Genetics. 2013 Apr;193(4):1107-15. doi: 10.1534/genetics.112.149054. Epub 2013 Feb 14.


The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes.

Ouedraogo M, Bettembourg C, Bretaudeau A, Sallou O, Diot C, Demeure O, Lecerf F.

PLoS One. 2012;7(11):e50653. doi: 10.1371/journal.pone.0050653. Epub 2012 Nov 28.


Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.

Gouadon E, Lecerf F, German-Fattal M.

J Pharm Pharm Sci. 2012;15(3):389-98.


A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.

Tu L, De Man FS, Girerd B, Huertas A, Chaumais MC, Lecerf F, François C, Perros F, Dorfmüller P, Fadel E, Montani D, Eddahibi S, Humbert M, Guignabert C.

Am J Respir Crit Care Med. 2012 Oct 1;186(7):666-76. doi: 10.1164/rccm.201202-0309OC. Epub 2012 Jul 12.


A study of magnesium deficiency in human and experimental pulmonary hypertension.

Chaumais MC, Lecerf F, Fattal S, Savale L, Günther S, Huertas A, Montani D, Perros F, Humbert M, German-Fattal M.

Magnes Res. 2012 Mar 1;25(1):21-7. doi: 10.1684/mrh.2012.0301.


Magnesium-deficiency does not alter calcineurin inhibitors activity in mice.

Hulin A, Lamrani L, Sabbagh F, Tallet A, Lecerf F, Bac P, German-Fattal M.

Transpl Immunol. 2012 Jan;26(1):55-61. doi: 10.1016/j.trim.2011.09.001. Epub 2011 Sep 13.


AnnotQTL: a new tool to gather functional and comparative information on a genomic region.

Lecerf F, Bretaudeau A, Sallou O, Desert C, Blum Y, Lagarrigue S, Demeure O.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W328-33. doi: 10.1093/nar/gkr361. Epub 2011 May 19.


Regulation of LPCAT3 by LXR.

Demeure O, Lecerf F, Duby C, Desert C, Ducheix S, Guillou H, Lagarrigue S.

Gene. 2011 Jan 1;470(1-2):7-11. doi: 10.1016/j.gene.2010.09.002. Epub 2010 Sep 15.


Fine mapping of the FecL locus influencing prolificacy in Lacaune sheep.

Drouilhet L, Lecerf F, Bodin L, Fabre S, Mulsant P.

Anim Genet. 2009 Dec;40(6):804-12. doi: 10.1111/j.1365-2052.2009.01919.x. Epub 2009 May 16.


QTL for resistance to Salmonella carrier state confirmed in both experimental and commercial chicken lines.

Calenge F, Lecerf F, Demars J, Feve K, Vignoles F, Pitel F, Vignal A, Velge P, Sellier N, Beaumont C.

Anim Genet. 2009 Oct;40(5):590-7. doi: 10.1111/j.1365-2052.2009.01884.x. Epub 2009 Apr 24.


Transcriptome profiling of the feeding-to-fasting transition in chicken liver.

Désert C, Duclos MJ, Blavy P, Lecerf F, Moreews F, Klopp C, Aubry M, Herault F, Le Roy P, Berri C, Douaire M, Diot C, Lagarrigue S.

BMC Genomics. 2008 Dec 17;9:611. doi: 10.1186/1471-2164-9-611.


An integrated approach of genetic resistance to Salmonella carrier state in fowls: from genetics to genomics and modelling.

Beaumont C, Lecerf F, Protais J, Calenge F, Prevost K, Lalmanach AC, Chapuis H, Pitel F, Burlot T, Sellier N, Fravalo P, Vignal A, Velge P.

Dev Biol (Basel). 2008;132:353-357. doi: 10.1159/000317185.


MarkerSet: a marker selection tool based on markers location and informativity in experimental designs.

Demeure O, Lecerf F.

BMC Res Notes. 2008 Mar 26;1:9. doi: 10.1186/1756-0500-1-9.


Effect of hypomagnesemia on allogeneic activation in mice.

Sabbagh F, Lecerf F, Hulin A, Bac P, German-Fattal M.

Transpl Immunol. 2008 Nov;20(1-2):83-7. doi: 10.1016/j.trim.2008.07.005. Epub 2008 Aug 14.


Impact of cyclosporine A on magnesium homeostasis: clinical observation in lung transplant recipients and experimental study in mice.

Sabbagh F, El Tawil Z, Lecerf F, Hulin A, Maurois P, Dartevelle P, Bac P, German-Fattal M.

Transplantation. 2008 Aug 15;86(3):436-44. doi: 10.1097/TP.0b013e31817fe069.


Neuroprotective gene profile in the brain of magnesium-deficient mice.

German-Fattal M, Lecerf F, Sabbagh F, Maurois P, Durlach J, Bac P.

Biomed Pharmacother. 2008 Apr-May;62(4):264-72. doi: 10.1016/j.biopha.2008.02.007. Epub 2008 Mar 24.


Allogeneic activation is attenuated in a model of mouse lung perfused with magnesium-deficient blood.

Sabbagh F, Lecerf F, Maurois P, Bac P, German-Fattal M.

Transpl Immunol. 2006 Nov;16(3-4):200-7. Epub 2006 Oct 3.


Effect of Mg-deficiency on endothelial cell allogeneic activation in a model of isolated perfused mouse lung.

Sabbagh F, Lecerf F, Maurois P, Bac P, German-Fattal M.

Magnes Res. 2005 Dec;18(4):235-40.


Severe Mg-deficiency is not associated with endothelial cell activation in mouse lung.

Sabbagh F, Lecerf F, Maurois P, Bac P, German-Fattal M.

Magnes Res. 2005 Dec;18(4):225-34.


Prolificacy genes in sheep: the French genetic programmes.

Mulsant P, Lecerf F, Fabre S, Bodin L, Thimonier J, Monget P, Lanneluc I, Monniaux D, Teyssier J, Elsen JM.

Reprod Suppl. 2003;61:353-9. Review.


The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor-IB functionality.

Fabre S, Pierre A, Pisselet C, Mulsant P, Lecerf F, Pohl J, Monget P, Monniaux D.

J Endocrinol. 2003 Jun;177(3):435-44.


Segregation of a major gene influencing ovulation in progeny of Lacaune meat sheep.

Bodin L, SanCristobal M, Lecerf F, Mulsant P, Bibé B, Lajous D, Belloc JP, Eychenne F, Amigues Y, Elsen JM.

Genet Sel Evol. 2002 Jul-Aug;34(4):447-64.


Regulation of ovarian folliculogenesis by IGF and BMP system in domestic animals.

Monget P, Fabre S, Mulsant P, Lecerf F, Elsen JM, Mazerbourg S, Pisselet C, Monniaux D.

Domest Anim Endocrinol. 2002 Jul;23(1-2):139-54. Review.


DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation.

Davis GH, Galloway SM, Ross IK, Gregan SM, Ward J, Nimbkar BV, Ghalsasi PM, Nimbkar C, Gray GD, Subandriyo, Inounu I, Tiesnamurti B, Martyniuk E, Eythorsdottir E, Mulsant P, Lecerf F, Hanrahan JP, Bradford GE, Wilson T.

Biol Reprod. 2002 Jun;66(6):1869-74.


Cytokine deviation induced by intrathymic injection of staphylococcal enterotoxin B (SEB).

Goettelfinger P, Lecerf F, Berrih-Aknin S, German-Fattal M.

Eur Cytokine Netw. 2001 Jul-Sep;12(3):487-500.


A novel method to isolate the common fraction of two DNA samples: hybrid specific amplification (HSA).

Lecerf F, Foggia L, Mulsant P, Bonnet A, Hatey F.

Nucleic Acids Res. 2001 Sep 1;29(17):E87-7.


Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes.

Mulsant P, Lecerf F, Fabre S, Schibler L, Monget P, Lanneluc I, Pisselet C, Riquet J, Monniaux D, Callebaut I, Cribiu E, Thimonier J, Teyssier J, Bodin L, Cognié Y, Chitour N, Elsen JM.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5104-9.


T cell deletion and unresponsiveness induced by intrathymic injection of staphylococcal enterotoxin B.

Goettelfinger P, Roussin R, Lecerf F, Berrih-Aknin S, Fattal-German M.

Transpl Immunol. 2000 Mar;8(1):39-48.


Kinetic analysis of microchimerism induced by intrathymic injection of allogeneic splenocytes in mice.

Guerra N, Goettelfinger P, Lecerf F, Berrih-Aknin S, German-Fattal M.

Transpl Immunol. 2000 Mar;8(1):31-7.


Establishment of a human thymic myoid cell line. Phenotypic and functional characteristics.

Wakkach A, Poea S, Chastre E, Gespach C, Lecerf F, De La Porte S, Tzartos S, Coulombe A, Berrih-Aknin S.

Am J Pathol. 1999 Oct;155(4):1229-40.


Expression and modulation of ICAM-1, TNF-alpha and RANTES in human alveolar macrophages from lung-transplant recipients in vitro.

Fattal-German M, Le Roy Ladurie F, Cerrina J, Lecerf F, Berrih-Aknin S.

Transpl Immunol. 1998 Sep;6(3):183-92.


Expression of ICAM-1 and TNF alpha in human alveolar macrophages from lung-transplant recipients.

Fattal-German M, Le Roy Ladurie F, Lecerf F, Berrih-Aknin S.

Ann N Y Acad Sci. 1996 Oct 31;796:138-48.


Modulation of ICAM-1 expression in human alveolar macrophages in vitro.

Fattal-German M, Ladurie FL, Cerrina J, Lecerf F, Berrih-Aknin S.

Eur Respir J. 1996 Mar;9(3):463-71.


Effect of intrathymic inoculation of spleen cells on T-cell depletion in adult mice.

Fattal-German M, Grinda JM, Lacour-Gayet F, Lecerf F, Berrih-Aknin S.

Transplant Proc. 1995 Aug;27(4):2495-6. No abstract available.


[Expression of intercellular adhesion molecule 1 (ICAM-1) on human alveolar macrophages].

Fattal-German M, Le Roy Ladurie F, Cerrina J, Lecerf F, Berrih-Aknin S.

Ann Pharm Fr. 1995;53(3):97-110. French.


Particular phenotypic profile of blood lymphocytes during obliterative bronchiolitis syndrome following lung transplantation.

Fattal-German M, Frachon I, Cerrina J, Ladurie FL, Lecerf F, Dartevelle P, Berrih-Aknin S.

Transpl Immunol. 1994 Sep;2(3):243-51.


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