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Items: 11


Targeting hypoxic cells through the DNA damage response.

Olcina M, Lecane PS, Hammond EM.

Clin Cancer Res. 2010 Dec 1;16(23):5624-9. doi: 10.1158/1078-0432.CCR-10-0286. Epub 2010 Sep 27. Review.


Effects of motexafin gadolinium in a phase II trial in refractory chronic lymphocytic leukemia.

Lin TS, Naumovski L, Lecane PS, Lucas MS, Moran ME, Cheney C, Lucas DM, Phan SC, Miller RA, Byrd JC.

Leuk Lymphoma. 2009 Dec;50(12):1977-82. doi: 10.3109/10428190903288464.


ATM activation and signaling under hypoxic conditions.

Bencokova Z, Kaufmann MR, Pires IM, Lecane PS, Giaccia AJ, Hammond EM.

Mol Cell Biol. 2009 Jan;29(2):526-37. doi: 10.1128/MCB.01301-08. Epub 2008 Nov 3.


Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.

Wang Z, Lecane PS, Thiemann P, Fan Q, Cortez C, Ma X, Tonev D, Miles D, Naumovski L, Miller RA, Magda D, Cho DG, Sessler JL, Pike BL, Yeligar SM, Karaman MW, Hacia JG.

Mol Cancer. 2007 Jan 19;6:9.


Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines.

Lecane PS, Karaman MW, Sirisawad M, Naumovski L, Miller RA, Hacia JG, Magda D.

Cancer Res. 2005 Dec 15;65(24):11676-88.


Leptomycin B stabilizes and activates p53 in primary prostatic epithelial cells and induces apoptosis in the LNCaP cell line.

Lecane PS, Kiviharju TM, Sellers RG, Peehl DM.

Prostate. 2003 Mar 1;54(4):258-67.


Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture.

Gallimore PH, Lecane PS, Roberts S, Rookes SM, Grand RJ, Parkhill J.

J Virol. 1997 Sep;71(9):6629-40.


The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.

Grand RJ, Lecane PS, Owen D, Grant ML, Roberts S, Levine AJ, Gallimore PH.

Virology. 1995 Jul 10;210(2):323-34.


Overexpression of wild-type p53 and c-Myc in human fetal cells transformed with adenovirus early region 1.

Grand RJ, Lecane PS, Roberts S, Grant ML, Lane DP, Young LS, Dawson CW, Gallimore PH.

Virology. 1993 Apr;193(2):579-91.


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