Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 45

1.

RNA accessibility impacts potency of Tough Decoy microRNA inhibitors.

Hooykaas MJG, Soppe JA, De Buhr HM, Kruse E, Wiertz EJHJ, Lebbink RJ.

RNA Biol. 2018 Oct 19:1-10. doi: 10.1080/15476286.2018.1537746. [Epub ahead of print]

PMID:
30339041
2.

Publisher Correction: Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, Vandenesch F, Van Strijp JAG, Lebbink RJ, Haas PA, Henry T, Spaan AN.

Nat Microbiol. 2018 Oct;3(10):1187. doi: 10.1038/s41564-018-0247-y.

PMID:
30177744
3.

Harnessing CRISPR to combat human viral infections.

de Buhr H, Lebbink RJ.

Curr Opin Immunol. 2018 Oct;54:123-129. doi: 10.1016/j.coi.2018.06.002. Epub 2018 Jul 26. Review.

4.

The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins.

Praest P, Luteijn RD, Brak-Boer IGJ, Lanfermeijer J, Hoelen H, Ijgosse L, Costa AI, Gorham RD Jr, Lebbink RJ, Wiertz EJHJ.

Mol Immunol. 2018 Sep;101:55-64. doi: 10.1016/j.molimm.2018.05.025. Epub 2018 Jun 4.

5.

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, Vandenesch F, Van Strijp JAG, Lebbink RJ, Haas PA, Henry T, Spaan AN.

Nat Microbiol. 2018 Jun;3(6):708-717. doi: 10.1038/s41564-018-0159-x. Epub 2018 May 7. Erratum in: Nat Microbiol. 2018 Oct;3(10):1187.

PMID:
29736038
6.

Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol.

Luteijn RD, Drexler I, Smith GL, Lebbink RJ, Wiertz EJHJ.

J Gen Virol. 2018 Jun;99(6):790-804. doi: 10.1099/jgv.0.001034. Epub 2018 Apr 20.

PMID:
29676720
7.

Comment on "Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells".

Evers M, Kruse E, Hamdan F, Lebbink RJ, Leusen JHW.

J Immunol. 2018 Apr 15;200(8):2515-2516. doi: 10.4049/jimmunol.1800087. No abstract available.

PMID:
29632250
8.

Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, Nielsen R, Komatsu M, Nejsum LN, Jakobsen MR, Gyrd-Hansen M, Paludan SR.

EMBO J. 2018 Apr 13;37(8). pii: e97858. doi: 10.15252/embj.201797858. Epub 2018 Mar 1.

PMID:
29496741
9.

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.

Döhner K, Ramos-Nascimento A, Bialy D, Anderson F, Hickford-Martinez A, Rother F, Koithan T, Rudolph K, Buch A, Prank U, Binz A, Hügel S, Lebbink RJ, Hoeben RC, Hartmann E, Bader M, Bauerfeind R, Sodeik B.

PLoS Pathog. 2018 Jan 5;14(1):e1006823. doi: 10.1371/journal.ppat.1006823. eCollection 2018 Jan.

10.

Multiple E2 ubiquitin-conjugating enzymes regulate human cytomegalovirus US2-mediated immunoreceptor downregulation.

van de Weijer ML, Schuren ABC, van den Boomen DJH, Mulder A, Claas FHJ, Lehner PJ, Lebbink RJ, Wiertz EJHJ.

J Cell Sci. 2017 Sep 1;130(17):2883-2892. doi: 10.1242/jcs.206839. Epub 2017 Jul 25.

11.

Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in Humans.

Soppe JA, Lebbink RJ.

Trends Microbiol. 2017 Oct;25(10):833-850. doi: 10.1016/j.tim.2017.04.005. Epub 2017 May 15. Review.

PMID:
28522157
12.

EBV MicroRNA BART16 Suppresses Type I IFN Signaling.

Hooykaas MJG, van Gent M, Soppe JA, Kruse E, Boer IGJ, van Leenen D, Groot Koerkamp MJA, Holstege FCP, Ressing ME, Wiertz EJHJ, Lebbink RJ.

J Immunol. 2017 May 15;198(10):4062-4073. doi: 10.4049/jimmunol.1501605. Epub 2017 Apr 17.

13.

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.

Jønsson KL, Laustsen A, Krapp C, Skipper KA, Thavachelvam K, Hotter D, Egedal JH, Kjolby M, Mohammadi P, Prabakaran T, Sørensen LK, Sun C, Jensen SB, Holm CK, Lebbink RJ, Johannsen M, Nyegaard M, Mikkelsen JG, Kirchhoff F, Paludan SR, Jakobsen MR.

Nat Commun. 2017 Feb 10;8:14391. doi: 10.1038/ncomms14391.

14.

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape.

Lebbink RJ, de Jong DC, Wolters F, Kruse EM, van Ham PM, Wiertz EJ, Nijhuis M.

Sci Rep. 2017 Feb 8;7:41968. doi: 10.1038/srep41968.

15.

RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.

Alkasalias T, Alexeyenko A, Hennig K, Danielsson F, Lebbink RJ, Fielden M, Turunen SP, Lehti K, Kashuba V, Madapura HS, Bozoky B, Lundberg E, Balland M, Guvén H, Klein G, Gad AK, Pavlova T.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1413-E1421. doi: 10.1073/pnas.1621161114. Epub 2017 Feb 7.

16.

CRISPR/Cas9, a powerful tool to target human herpesviruses.

van Diemen FR, Lebbink RJ.

Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12694. Epub 2016 Dec 23. Review.

PMID:
27860066
17.

The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein.

van de Weijer ML, van Muijlwijk GH, Visser LJ, Costa AI, Wiertz EJ, Lebbink RJ.

Viruses. 2016 Nov 15;8(11). pii: E309.

18.

Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines.

Hooykaas MJ, Kruse E, Wiertz EJ, Lebbink RJ.

BMC Genomics. 2016 Aug 17;17:644. doi: 10.1186/s12864-016-2978-6.

19.

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections.

van Diemen FR, Kruse EM, Hooykaas MJ, Bruggeling CE, Schürch AC, van Ham PM, Imhof SM, Nijhuis M, Wiertz EJ, Lebbink RJ.

PLoS Pathog. 2016 Jun 30;12(6):e1005701. doi: 10.1371/journal.ppat.1005701. eCollection 2016 Jun.

20.

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor.

Sebestyen Z, Scheper W, Vyborova A, Gu S, Rychnavska Z, Schiffler M, Cleven A, Chéneau C, van Noorden M, Peigné CM, Olive D, Lebbink RJ, Oostvogels R, Mutis T, Schuurhuis GJ, Adams EJ, Scotet E, Kuball J.

Cell Rep. 2016 May 31;15(9):1973-85. doi: 10.1016/j.celrep.2016.04.081. Epub 2016 May 19.

21.

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells.

Gram AM, Oosenbrug T, Lindenbergh MF, Büll C, Comvalius A, Dickson KJ, Wiegant J, Vrolijk H, Lebbink RJ, Wolterbeek R, Adema GJ, Griffioen M, Heemskerk MH, Tscharke DC, Hutt-Fletcher LM, Wiertz EJ, Hoeben RC, Ressing ME.

PLoS Pathog. 2016 Apr 14;12(4):e1005550. doi: 10.1371/journal.ppat.1005550. eCollection 2016 Apr.

22.

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, Hornung V, Lebbink RJ, Duch M, Fitzgerald KA, Bahrami S, Mikkelsen JG, Hartmann R, Paludan SR.

Nat Commun. 2016 Feb 19;7:10680. doi: 10.1038/ncomms10680.

23.

Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression.

Benedictus L, Luteijn RD, Otten H, Lebbink RJ, van Kooten PJ, Wiertz EJ, Rutten VP, Koets AP.

Sci Rep. 2015 Aug 3;5:12748. doi: 10.1038/srep12748.

24.

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

Hoelen H, Zaldumbide A, van Leeuwen WF, Torfs EC, Engelse MA, Hassan C, Lebbink RJ, de Koning EJ, Resssing ME, de Ru AH, van Veelen PA, Hoeben RC, Roep BO, Wiertz EJ.

PLoS One. 2015 Jun 24;10(6):e0128206. doi: 10.1371/journal.pone.0128206. eCollection 2015.

25.

Efficient intracellular delivery of native proteins.

D'Astolfo DS, Pagliero RJ, Pras A, Karthaus WR, Clevers H, Prasad V, Lebbink RJ, Rehmann H, Geijsen N.

Cell. 2015 Apr 23;161(3):674-690. doi: 10.1016/j.cell.2015.03.028.

26.

Silencing the shutoff protein of Epstein-Barr virus in productively infected B cells points to (innate) targets for immune evasion.

van Gent M, Gram AM, Boer IG, Geerdink RJ, Lindenbergh MF, Lebbink RJ, Wiertz EJ, Ressing ME.

J Gen Virol. 2015 Apr;96(Pt 4):858-65. doi: 10.1099/jgv.0.000021. Epub 2014 Dec 12.

PMID:
25502648
27.

Systematic identification of barriers to human iPSC generation.

Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M.

Cell. 2014 Jul 17;158(2):449-461. doi: 10.1016/j.cell.2014.05.040.

28.

Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.

Luteijn RD, Hoelen H, Kruse E, van Leeuwen WF, Grootens J, Horst D, Koorengevel M, Drijfhout JW, Kremmer E, Früh K, Neefjes JJ, Killian A, Lebbink RJ, Ressing ME, Wiertz EJ.

J Immunol. 2014 Aug 15;193(4):1578-89. doi: 10.4049/jimmunol.1400964. Epub 2014 Jul 14.

29.

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.

van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ.

Nat Commun. 2014 May 8;5:3832. doi: 10.1038/ncomms4832.

30.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

Cell. 2013 Feb 14;152(4):909-22. doi: 10.1016/j.cell.2013.01.030. Epub 2013 Feb 8.

31.

Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs.

Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT.

PLoS One. 2011;6(10):e26213. doi: 10.1371/journal.pone.0026213. Epub 2011 Oct 21.

32.

Signal inhibitory receptor on leukocytes-1 is a novel functional inhibitory immune receptor expressed on human phagocytes.

Steevels TA, Lebbink RJ, Westerlaken GH, Coffer PJ, Meyaard L.

J Immunol. 2010 May 1;184(9):4741-8. doi: 10.4049/jimmunol.0902039. Epub 2010 Apr 7.

33.

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI.

Brondijk TH, de Ruiter T, Ballering J, Wienk H, Lebbink RJ, van Ingen H, Boelens R, Farndale RW, Meyaard L, Huizinga EG.

Blood. 2010 Feb 18;115(7):1364-73. doi: 10.1182/blood-2009-10-246322. Epub 2009 Dec 10.

34.

Rapid creation and quantitative monitoring of high coverage shRNA libraries.

Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT.

Nat Methods. 2009 Jun;6(6):443-5. doi: 10.1038/nmeth.1330. Epub 2009 May 17.

35.

Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.

Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT.

J Biol Chem. 2009 Jul 3;284(27):18515-24. doi: 10.1074/jbc.M109.006676. Epub 2009 May 6.

36.

Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III.

Lebbink RJ, Raynal N, de Ruiter T, Bihan DG, Farndale RW, Meyaard L.

Matrix Biol. 2009 May;28(4):202-10. doi: 10.1016/j.matbio.2009.03.005. Epub 2009 Apr 2.

PMID:
19345263
37.

The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction.

Lebbink RJ, van den Berg MC, de Ruiter T, Raynal N, van Roon JA, Lenting PJ, Jin B, Meyaard L.

J Immunol. 2008 Feb 1;180(3):1662-9.

38.

Mouse leukocyte-associated Ig-like receptor-1 (mLAIR-1) functions as an inhibitory collagen-binding receptor on immune cells.

Lebbink RJ, de Ruiter T, Kaptijn GJ, Bihan DG, Jansen CA, Lenting PJ, Meyaard L.

Int Immunol. 2007 Aug;19(8):1011-9. Epub 2007 Aug 16.

PMID:
17702987
39.

Non-MHC ligands for inhibitory immune receptors: novel insights and implications for immune regulation.

Lebbink RJ, Meyaard L.

Mol Immunol. 2007 Mar;44(9):2153-64. Epub 2006 Dec 22. Review.

PMID:
17188357
40.

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1.

Lebbink RJ, de Ruiter T, Adelmeijer J, Brenkman AB, van Helvoort JM, Koch M, Farndale RW, Lisman T, Sonnenberg A, Lenting PJ, Meyaard L.

J Exp Med. 2006 Jun 12;203(6):1419-25. Epub 2006 Jun 5.

41.

Identification and characterization of the rat homologue of LAIR-1.

Lebbink RJ, de Ruiter T, Kaptijn GJ, Meyaard L.

Immunogenetics. 2005 Jun;57(5):344-51. Epub 2005 May 18.

PMID:
15902436
43.

High-throughput screening of mutant alpha-amylase libraries for increased activity at 129 degrees C.

Berk H, Lebbink RJ.

Methods Mol Biol. 2003;230:127-35. No abstract available.

PMID:
12824575
44.

The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability.

Brinkman AB, Bell SD, Lebbink RJ, de Vos WM, van der Oost J.

J Biol Chem. 2002 Aug 16;277(33):29537-49. Epub 2002 May 31.

45.

Identification of a novel occlusion derived virus-specific protein in Spodoptera exigua multicapsid nucleopolyhedrovirus.

IJkel WF, Lebbink RJ, Op den Brouw ML, Goldbach RW, Vlak JM, Zuidema D.

Virology. 2001 Jun 5;284(2):170-81.

Supplemental Content

Loading ...
Support Center