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Items: 10


TAT-protein blockade during ischemia/reperfusion reveals critical role for p85 PI3K-PTEN interaction in cardiomyocyte injury.

Zhu X, Shao ZH, Li C, Li J, Zhong Q, Learoyd J, Meliton A, Meliton L, Leff AR, Vanden Hoek TL.

PLoS One. 2014 Apr 21;9(4):e95622. doi: 10.1371/journal.pone.0095622. eCollection 2014.


Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury.

Duan Y, Learoyd J, Meliton AY, Leff AR, Zhu X.

Respir Res. 2012 Jan 18;13:4. doi: 10.1186/1465-9921-13-4.


Hematopoietic Pyk2 regulates migration of differentiated HL-60 cells.

Wang L, Learoyd J, Duan Y, Leff AR, Zhu X.

J Inflamm (Lond). 2010 May 27;7:26. doi: 10.1186/1476-9255-7-26.


Inhibition of Pyk2 blocks airway inflammation and hyperresponsiveness in a mouse model of asthma.

Duan Y, Learoyd J, Meliton AY, Clay BS, Leff AR, Zhu X.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):491-7. doi: 10.1165/rcmb.2008-0469OC. Epub 2009 Jun 11.


Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion.

Zhu X, Boetticher E, Wang L, Duan Y, Learoyd J, Leff AR.

Am J Respir Cell Mol Biol. 2008 Sep;39(3):263-9. doi: 10.1165/rcmb.2008-0047OC. Epub 2008 Mar 26.


Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel.

Zhu X, Learoyd J, Butt S, Zhu L, Usatyuk PV, Natarajan V, Munoz NM, Leff AR.

Am J Respir Cell Mol Biol. 2007 May;36(5):585-93. Epub 2007 Jan 11.


Phosphodiesterase 4 inhibition of beta2-integrin adhesion caused by leukotriene B4 and TNF-alpha in human neutrophils.

Meliton AY, Muñoz NM, Lambertino A, Boetticher E, Learoyd J, Zhu X, Leff AR.

Eur Respir J. 2006 Nov;28(5):920-8. Epub 2006 Jun 28.


Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils.

Muñoz NM, Meliton AY, Lambertino A, Boetticher E, Learoyd J, Sultan F, Zhu X, Cho W, Leff AR.

J Immunol. 2006 Jul 1;177(1):574-82.


Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase.

Sano M, Leff AR, Myou S, Boetticher E, Meliton AY, Learoyd J, Lambertino AT, Munoz NM, Zhu X.

Am J Respir Cell Mol Biol. 2005 Jul;33(1):65-70. Epub 2005 Mar 31.


Glucocorticoid-induced surface expression of annexin 1 blocks beta2-integrin adhesion of human eosinophils to intercellular adhesion molecule 1 surrogate protein.

Liu J, Zhu X, Myo S, Lambertino AT, Xu C, Boetticher E, Muñoz NM, Sano M, Cordoba M, Learoyd J, Meliton A, Johnson M, Leff AR.

J Allergy Clin Immunol. 2005 Mar;115(3):493-500.


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