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No substantial long-term bias in the Cenozoic benthic foraminifera oxygen-isotope record.

Evans D, Badger MPS, Foster GL, Henehan MJ, Lear CH, Zachos JC.

Nat Commun. 2018 Jul 23;9(1):2875. doi: 10.1038/s41467-018-05303-4. No abstract available.


The fetus at the tipping point: modifying the outcome of fetal asphyxia.

Dhillon SK, Lear CA, Galinsky R, Wassink G, Davidson JO, Juul S, Robertson NJ, Gunn AJ, Bennet L.

J Physiol. 2018 May 17. doi: 10.1113/JP274949. [Epub ahead of print]


A working model for hypothermic neuroprotection.

Wassink G, Davidson JO, Lear CA, Juul SE, Northington F, Bennet L, Gunn AJ.

J Physiol. 2018 Apr 16. doi: 10.1113/JP274928. [Epub ahead of print]


The peripheral chemoreflex: indefatigable guardian of fetal physiological adaptation to labour.

Lear CA, Wassink G, Westgate JA, Nijhuis JG, Ugwumadu A, Galinsky R, Bennet L, Gunn AJ.

J Physiol. 2018 Mar 31. doi: 10.1113/JP274937. [Epub ahead of print]


Time and sex dependent effects of magnesium sulphate on post-asphyxial seizures in preterm fetal sheep.

Bennet L, Galinsky R, Draghi V, Lear CA, Davidson JO, Unsworth CP, Gunn AJ.

J Physiol. 2018 Mar 23. doi: 10.1113/JP275627. [Epub ahead of print]


Magnesium sulfate and sex differences in cardiovascular and neural adaptations during normoxia and asphyxia in preterm fetal sheep.

Galinsky R, Dhillon SK, Lear CA, Yamaguchi K, Wassink G, Gunn AJ, Bennet L.

Am J Physiol Regul Integr Comp Physiol. 2018 Aug 1;315(2):R205-R217. doi: 10.1152/ajpregu.00390.2017. Epub 2018 Mar 21.


Sea ice dynamics across the Mid-Pleistocene transition in the Bering Sea.

Detlef H, Belt ST, Sosdian SM, Smik L, Lear CH, Hall IR, Cabedo-Sanz P, Husum K, Kender S.

Nat Commun. 2018 Mar 5;9(1):941. doi: 10.1038/s41467-018-02845-5.


Evolving changes in fetal heart rate variability and brain injury after hypoxia-ischaemia in preterm fetal sheep.

Yamaguchi K, Lear CA, Beacom MJ, Ikeda T, Gunn AJ, Bennet L.

J Physiol. 2018 Jan 8. doi: 10.1113/JP275434. [Epub ahead of print]


Chronic inflammation and impaired development of the preterm brain.

Bennet L, Dhillon S, Lear CA, van den Heuij L, King V, Dean JM, Wassink G, Davidson JO, Gunn AJ.

J Reprod Immunol. 2018 Feb;125:45-55. doi: 10.1016/j.jri.2017.11.003. Epub 2017 Nov 26. Review.


Complex interactions between hypoxia-ischemia and inflammation in preterm brain injury.

Galinsky R, Lear CA, Dean JM, Wassink G, Dhillon SK, Fraser M, Davidson JO, Bennet L, Gunn AJ.

Dev Med Child Neurol. 2018 Feb;60(2):126-133. doi: 10.1111/dmcn.13629. Epub 2017 Dec 1. Review.


An investigation of fetal behavioural states during maternal sleep in healthy late gestation pregnancy: an observational study.

Stone PR, Burgess W, McIntyre J, Gunn AJ, Lear CA, Bennet L, Mitchell EA, Thompson JMD; Maternal Sleep In Pregnancy Research Group The University of Auckland.

J Physiol. 2017 Dec 15;595(24):7441-7450. doi: 10.1113/JP275084. Epub 2017 Nov 2.


Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.

van den Heuij LG, Fraser M, Miller SL, Jenkin G, Wallace EM, Davidson JO, Lear CA, Lim R, Wassink G, Gunn AJ, Bennet L.

J Cereb Blood Flow Metab. 2017 Jan 1:271678X17729954. doi: 10.1177/0271678X17729954. [Epub ahead of print]


Reply from Christopher A. Lear, Robert Galinsky, Guido Wassink, Kyohei Yamaguchi, Joanne O. Davidson, Jenny A. Westgate, Laura Bennet and Alistair J. Gunn.

Lear CA, Galinsky R, Wassink G, Yamaguchi K, Davidson JO, Westgate JA, Bennet L, Gunn AJ.

J Physiol. 2017 Sep 1;595(17):6081-6083. doi: 10.1113/JP274800. No abstract available.


Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep.

Galinsky R, Davidson JO, Lear CA, Bennet L, Green CR, Gunn AJ.

Sci Rep. 2017 Jul 24;7(1):6304. doi: 10.1038/s41598-017-06683-1.


Antenatal dexamethasone before asphyxia promotes cystic neural injury in preterm fetal sheep by inducing hyperglycemia.

Lear CA, Davidson JO, Mackay GR, Drury PP, Galinsky R, Quaedackers JS, Gunn AJ, Bennet L.

J Cereb Blood Flow Metab. 2018 Apr;38(4):706-718. doi: 10.1177/0271678X17703124. Epub 2017 Apr 7.


In the Era of Therapeutic Hypothermia, How Well Do Studies of Perinatal Neuroprotection Control Temperature?

Galinsky R, Dean JM, Lear CA, Davidson JO, Dhillon S, Wassink G, Bennet L, Gunn AJ.

Dev Neurosci. 2017;39(1-4):7-22. doi: 10.1159/000452859. Epub 2016 Dec 17. Review.


Effect of maternal position on fetal behavioural state and heart rate variability in healthy late gestation pregnancy.

Stone PR, Burgess W, McIntyre JP, Gunn AJ, Lear CA, Bennet L, Mitchell EA, Thompson JM; Maternal Sleep In Pregnancy Research Group, The University of Auckland.

J Physiol. 2017 Feb 15;595(4):1213-1221. doi: 10.1113/JP273201. Epub 2016 Dec 11.


Cholinergic and β-adrenergic control of cardiovascular reflex responses to brief repeated asphyxia in term-equivalent fetal sheep.

Galinsky R, Lear CA, Yamaguchi K, Wassink G, Westgate JA, Bennet L, Gunn AJ.

Am J Physiol Regul Integr Comp Physiol. 2016 Nov;311(5):R949-R956. doi: 10.1152/ajpregu.00340.2016. Epub 2016 Sep 21.


The myths and physiology surrounding intrapartum decelerations: the critical role of the peripheral chemoreflex.

Lear CA, Galinsky R, Wassink G, Yamaguchi K, Davidson JO, Westgate JA, Bennet L, Gunn AJ.

J Physiol. 2016 Sep 1;594(17):4711-25. doi: 10.1113/JP271205. Epub 2016 May 27. Review.


Magnesium sulfate reduces EEG activity but is not neuroprotective after asphyxia in preterm fetal sheep.

Galinsky R, Draghi V, Wassink G, Davidson JO, Drury PP, Lear CA, Gunn AJ, Bennet L.

J Cereb Blood Flow Metab. 2017 Apr;37(4):1362-1373. doi: 10.1177/0271678X16655548. Epub 2016 Jan 1.


CLIMATE. How Antarctica got its ice.

Lear CH, Lunt DJ.

Science. 2016 Apr 1;352(6281):34-5. doi: 10.1126/science.aad6284. Epub 2016 Mar 10. No abstract available.


Subclinical decelerations during developing hypotension in preterm fetal sheep after acute on chronic lipopolysaccharide exposure.

Lear CA, Davidson JO, Galinsky R, Yuill CA, Wassink G, Booth LC, Drury PP, Bennet L, Gunn AJ.

Sci Rep. 2015 Nov 5;5:16201. doi: 10.1038/srep16201.


Use of Electronic Nurse Reminders to Improve Documentation: A Process Improvement for a Comprehensive Stroke Center.

Lear CL, Walters C.

Comput Inform Nurs. 2015 Dec;33(12):523-9. doi: 10.1097/CIN.0000000000000199.


Atmospheric and oceanic impacts of Antarctic glaciation across the Eocene-Oligocene transition.

Kennedy AT, Farnsworth A, Lunt DJ, Lear CH, Markwick PJ.

Philos Trans A Math Phys Eng Sci. 2015 Nov 13;373(2054). pii: 20140419. doi: 10.1098/rsta.2014.0419.


Magnesium sulphate and cardiovascular and cerebrovascular adaptations to asphyxia in preterm fetal sheep.

Galinsky R, Davidson JO, Drury PP, Wassink G, Lear CA, van den Heuij LG, Gunn AJ, Bennet L.

J Physiol. 2016 Mar 1;594(5):1281-93. doi: 10.1113/JP270614. Epub 2015 Jul 8.


Sympathetic neural activation does not mediate heart rate variability during repeated brief umbilical cord occlusions in near-term fetal sheep.

Lear CA, Galinsky R, Wassink G, Mitchell CJ, Davidson JO, Westgate JA, Bennet L, Gunn AJ.

J Physiol. 2016 Mar 1;594(5):1265-77. doi: 10.1113/JP270125. Epub 2015 May 22.


Potential neuroprotective strategies for perinatal infection and inflammation.

Ranchhod SM, Gunn KC, Fowke TM, Davidson JO, Lear CA, Bai J, Bennet L, Mallard C, Gunn AJ, Dean JM.

Int J Dev Neurosci. 2015 Oct;45:44-54. doi: 10.1016/j.ijdevneu.2015.02.006. Epub 2015 Feb 19. Review.


Analgesics, sedatives, anticonvulsant drugs, and the cooled brain.

Wassink G, Lear CA, Gunn KC, Dean JM, Bennet L, Gunn AJ.

Semin Fetal Neonatal Med. 2015 Apr;20(2):109-14. doi: 10.1016/j.siny.2014.10.003. Epub 2014 Nov 1. Review.


The effects of dexamethasone on post-asphyxial cerebral oxygenation in the preterm fetal sheep.

Lear CA, Koome ME, Davidson JO, Drury PP, Quaedackers JS, Galinsky R, Gunn AJ, Bennet L.

J Physiol. 2014 Dec 15;592(24):5493-505. doi: 10.1113/jphysiol.2014.281253. Epub 2014 Nov 10.


Paradoxical air embolism and neurological insult during removal of a pulmonary artery catheter introducer.

Bowles PF, Lear C, Maccario M, Kong R.

BMJ Case Rep. 2014 Jul 10;2014. pii: bcr2014203976. doi: 10.1136/bcr-2014-203976.


Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure.

Lear CA, Davidson JO, Booth LC, Wassink G, Galinsky R, Drury PP, Fraser M, Bennet L, Gunn AJ.

Am J Physiol Regul Integr Comp Physiol. 2014 Aug 15;307(4):R387-95. doi: 10.1152/ajpregu.00110.2014. Epub 2014 Jun 18.


Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep.

van den Heuij LG, Mathai S, Davidson JO, Lear CA, Booth LC, Fraser M, Gunn AJ, Bennet L.

J Neuroinflammation. 2014 May 16;11:89. doi: 10.1186/1742-2094-11-89.


Magnesium is not consistently neuroprotective for perinatal hypoxia-ischemia in term-equivalent models in preclinical studies: a systematic review.

Galinsky R, Bennet L, Groenendaal F, Lear CA, Tan S, van Bel F, Juul SE, Robertson NJ, Mallard C, Gunn AJ.

Dev Neurosci. 2014;36(2):73-82. Review.


FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

Johansen LM, Brannan JM, Delos SE, Shoemaker CJ, Stossel A, Lear C, Hoffstrom BG, Dewald LE, Schornberg KL, Scully C, Lehár J, Hensley LE, White JM, Olinger GG.

Sci Transl Med. 2013 Jun 19;5(190):190ra79. doi: 10.1126/scitranslmed.3005471.


Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors.

Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC.

PLoS One. 2013;8(4):e60838. doi: 10.1371/journal.pone.0060838. Epub 2013 Apr 2.


Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques.

Olinger GG Jr, Pettitt J, Kim D, Working C, Bohorov O, Bratcher B, Hiatt E, Hume SD, Johnson AK, Morton J, Pauly M, Whaley KJ, Lear CM, Biggins JE, Scully C, Hensley L, Zeitlin L.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18030-5. doi: 10.1073/pnas.1213709109. Epub 2012 Oct 15.


High-dose mannose-binding lectin therapy for Ebola virus infection.

Michelow IC, Lear C, Scully C, Prugar LI, Longley CB, Yantosca LM, Ji X, Karpel M, Brudner M, Takahashi K, Spear GT, Ezekowitz RA, Schmidt EV, Olinger GG.

J Infect Dis. 2011 Jan 15;203(2):175-9. doi: 10.1093/infdis/jiq025.


A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus.

Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV.

J Biol Chem. 2010 Aug 6;285(32):24729-39. doi: 10.1074/jbc.M110.106260. Epub 2010 Jun 1.


FGI-104: a broad-spectrum small molecule inhibitor of viral infection.

Kinch MS, Yunus AS, Lear C, Mao H, Chen H, Fesseha Z, Luo G, Nelson EA, Li L, Huang Z, Murray M, Ellis WY, Hensley L, Christopher-Hennings J, Olinger GG, Goldblatt M.

Am J Transl Res. 2009 Jan 5;1(1):87-98.


Thresholds for Cenozoic bipolar glaciation.

Deconto RM, Pollard D, Wilson PA, Pälike H, Lear CH, Pagani M.

Nature. 2008 Oct 2;455(7213):652-6. doi: 10.1038/nature07337.


The heartbeat of the Oligocene climate system.

Pälike H, Norris RD, Herrle JO, Wilson PA, Coxall HK, Lear CH, Shackleton NJ, Tripati AK, Wade BS.

Science. 2006 Dec 22;314(5807):1894-8.


Rapid stepwise onset of Antarctic glaciation and deeper calcite compensation in the Pacific Ocean.

Coxall HK, Wilson PA, Pälike H, Lear CH, Backman J.

Nature. 2005 Jan 6;433(7021):53-7.


Cenozoic deep-Sea temperatures and global ice volumes from Mg/Ca in benthic foraminiferal calcite

Lear CH, Elderfield H, Wilson PA.

Science. 2000 Jan 14;287(5451):269-72.


Molecular heterogeneity of PAF in normal human mixed saliva: quantitative mass spectral analysis after direct derivatization of PAF with pentafluorobenzoic anhydride.

Woodard DS, Mealey BL, Lear CS, Satsangi RK, Prihoda TJ, Weintraub ST, Pinckard RN, McManus LM.

Biochim Biophys Acta. 1995 Nov 16;1259(2):137-47.


Automated DNA purification for fluorescent sequencing.

Lear C.

Am Biotechnol Lab. 1995 Feb;13(3):100. No abstract available.


The effect of garlic extract on human metabolism of acetaminophen.

Gwilt PR, Lear CL, Tempero MA, Birt DD, Grandjean AC, Ruddon RW, Nagel DL.

Cancer Epidemiol Biomarkers Prev. 1994 Mar;3(2):155-60.


Twin block appliances.

Lear CS.

J Can Dent Assoc. 1993 Jan;59(1):7. No abstract available.


Radiation-induced increased platelet-activating factor activity in mixed saliva.

McManus LM, Ostrom KK, Lear C, Luce EB, Gander DL, Pinckard RN, Redding SW.

Lab Invest. 1993 Jan;68(1):118-24.


Differential responsiveness of human neutrophils to the autocrine actions of 1-O-alkyl-homologs and 1-acyl analogs of platelet-activating factor.

Pinckard RN, Showell HJ, Castillo R, Lear C, Breslow R, McManus LM, Woodard DS, Ludwig JC.

J Immunol. 1992 Jun 1;148(11):3528-35.


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