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Items: 36


Wnt5a is a TLR2/4-ligand that induces tolerance in human myeloid cells.

Mehmeti M, Bergenfelz C, Källberg E, Millrud CR, Björk P, Ivars F, Johansson-Lindbom B, Kjellström S, André I, Leandersson K.

Commun Biol. 2019 May 9;2:176. doi: 10.1038/s42003-019-0432-4. eCollection 2019.


Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.

Svensson MC, Borg D, Zhang C, Hedner C, Nodin B, Uhlén M, Mardinoglu A, Leandersson K, Jirström K.

Front Oncol. 2019 Mar 13;9:136. doi: 10.3389/fonc.2019.00136. eCollection 2019.


Expression of programmed cell death protein 1 (PD-1) and its ligand PD-L1 in colorectal cancer: Relationship with sidedness and prognosis.

Berntsson J, Eberhard J, Nodin B, Leandersson K, Larsson AH, Jirström K.

Oncoimmunology. 2018 Jun 11;7(8):e1465165. doi: 10.1080/2162402X.2018.1465165. eCollection 2018.


Docetaxel promotes the generation of anti-tumorigenic human macrophages.

Millrud CR, Mehmeti M, Leandersson K.

Exp Cell Res. 2018 Jan 15;362(2):525-531. doi: 10.1016/j.yexcr.2017.12.018. Epub 2017 Dec 19.


The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma.

Svensson MC, Warfvinge CF, Fristedt R, Hedner C, Borg D, Eberhard J, Micke P, Nodin B, Leandersson K, Jirström K.

Oncotarget. 2017 Jul 21;8(42):72108-72126. doi: 10.18632/oncotarget.19437. eCollection 2017 Sep 22.


Infiltration of γ⁢δ T cells, IL-17+ T cells and FoxP3+ T cells in human breast cancer.

Allaoui R, Hagerling C, Desmond E, Warfvinge CF, Jirström K, Leandersson K.

Cancer Biomark. 2017 Dec 8;20(4):395-409. doi: 10.3233/CBM-170026.


Papillary renal cell carcinoma-derived chemerin, IL-8, and CXCL16 promote monocyte recruitment and differentiation into foam-cell macrophages.

Krawczyk KM, Nilsson H, Allaoui R, Lindgren D, Arvidsson M, Leandersson K, Johansson ME.

Lab Invest. 2017 Nov;97(11):1296-1305. doi: 10.1038/labinvest.2017.78. Epub 2017 Jul 31.


The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study.

Berntsson J, Svensson MC, Leandersson K, Nodin B, Micke P, Larsson AH, Eberhard J, Jirström K.

Int J Cancer. 2017 Oct 15;141(8):1654-1666. doi: 10.1002/ijc.30869. Epub 2017 Jul 20.


The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype.

Lundgren S, Karnevi E, Elebro J, Nodin B, Karlsson MCI, Eberhard J, Leandersson K, Jirström K.

J Transl Med. 2017 Jul 3;15(1):152. doi: 10.1186/s12967-017-1256-y.


Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer.

Englund E, Bartoschek M, Reitsma B, Jacobsson L, Escudero-Esparza A, Orimo A, Leandersson K, Hagerling C, Aspberg A, Storm P, Okroj M, Mulder H, Jirström K, Pietras K, Blom AM.

Oncogene. 2016 Oct 27;35(43):5585-5596. doi: 10.1038/onc.2016.98. Epub 2016 Apr 11.


Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers.

Allaoui R, Bergenfelz C, Mohlin S, Hagerling C, Salari K, Werb Z, Anderson RL, Ethier SP, Jirström K, Påhlman S, Bexell D, Tahin B, Johansson ME, Larsson C, Leandersson K.

Nat Commun. 2016 Oct 11;7:13050. doi: 10.1038/ncomms13050.


On the origin of myeloid-derived suppressor cells.

Millrud CR, Bergenfelz C, Leandersson K.

Oncotarget. 2017 Jan 10;8(2):3649-3665. doi: 10.18632/oncotarget.12278. Review.


The Prognostic Impact of NK/NKT Cell Density in Periampullary Adenocarcinoma Differs by Morphological Type and Adjuvant Treatment.

Lundgren S, Warfvinge CF, Elebro J, Heby M, Nodin B, Krzyzanowska A, Bjartell A, Leandersson K, Eberhard J, Jirström K.

PLoS One. 2016 Jun 8;11(6):e0156497. doi: 10.1371/journal.pone.0156497. eCollection 2016.


Dual mechanisms of action of the RNA-binding protein human antigen R explains its regulatory effect on melanoma cell migration.

Moradi F, Berglund P, Linnskog R, Leandersson K, Andersson T, Prasad CP.

Transl Res. 2016 Jun;172:45-60. doi: 10.1016/j.trsl.2016.02.007. Epub 2016 Feb 23.


S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.

Bergenfelz C, Gaber A, Allaoui R, Mehmeti M, Jirström K, Leanderson T, Leandersson K.

Br J Cancer. 2015 Oct 20;113(8):1234-43. doi: 10.1038/bjc.2015.346. Epub 2015 Oct 8.


Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer.

Mehmeti M, Allaoui R, Bergenfelz C, Saal LH, Ethier SP, Johansson ME, Jirström K, Leandersson K.

Breast Cancer Res. 2015 Sep 22;17:130. doi: 10.1186/s13058-015-0640-x.


Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients.

Bergenfelz C, Larsson AM, von Stedingk K, Gruvberger-Saal S, Aaltonen K, Jansson S, Jernström H, Janols H, Wullt M, Bredberg A, Rydén L, Leandersson K.

PLoS One. 2015 May 20;10(5):e0127028. doi: 10.1371/journal.pone.0127028. eCollection 2015.


Prognostic stromal gene signatures in breast cancer.

Winslow S, Leandersson K, Edsjö A, Larsson C.

Breast Cancer Res. 2015 Feb 21;17:23. doi: 10.1186/s13058-015-0530-2.


A high frequency of MDSCs in sepsis patients, with the granulocytic subtype dominating in gram-positive cases.

Janols H, Bergenfelz C, Allaoui R, Larsson AM, Rydén L, Björnsson S, Janciauskiene S, Wullt M, Bredberg A, Leandersson K.

J Leukoc Biol. 2014 Nov;96(5):685-93. doi: 10.1189/jlb.5HI0214-074R. Epub 2014 Jun 13.


Infiltration of CD3⁺ and CD68⁺ cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors.

Sjödahl G, Lövgren K, Lauss M, Chebil G, Patschan O, Gudjonsson S, Månsson W, Fernö M, Leandersson K, Lindgren D, Liedberg F, Höglund M.

Urol Oncol. 2014 Aug;32(6):791-7. doi: 10.1016/j.urolonc.2014.02.007. Epub 2014 Apr 29.


WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells.

Ekström EJ, Bergenfelz C, von Bülow V, Serifler F, Carlemalm E, Jönsson G, Andersson T, Leandersson K.

Mol Cancer. 2014 Apr 26;13:88. doi: 10.1186/1476-4598-13-88.


Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells.

Winslow S, Leandersson K, Larsson C.

Mol Cancer. 2013 Dec 9;12(1):156. doi: 10.1186/1476-4598-12-156.


Heterogeneity among septic shock patients in a set of immunoregulatory markers.

Janols H, Wullt M, Bergenfelz C, Björnsson S, Lickei H, Janciauskiene S, Leandersson K, Bredberg A.

Eur J Clin Microbiol Infect Dis. 2014 Mar;33(3):313-24. doi: 10.1007/s10096-013-1957-y. Epub 2013 Aug 29.


Wnt5a inhibits human monocyte-derived myeloid dendritic cell generation.

Bergenfelz C, Janols H, Wullt M, Jirström K, Bredberg A, Leandersson K.

Scand J Immunol. 2013 Aug;78(2):194-204. doi: 10.1111/sji.12075.


The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients.

Medrek C, Pontén F, Jirström K, Leandersson K.

BMC Cancer. 2012 Jul 23;12:306. doi: 10.1186/1471-2407-12-306.


Wnt5a induces a tolerogenic phenotype of macrophages in sepsis and breast cancer patients.

Bergenfelz C, Medrek C, Ekström E, Jirström K, Janols H, Wullt M, Bredberg A, Leandersson K.

J Immunol. 2012 Jun 1;188(11):5448-58. doi: 10.4049/jimmunol.1103378. Epub 2012 Apr 30.


Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.

Medrek C, Landberg G, Andersson T, Leandersson K.

J Biol Chem. 2009 Apr 17;284(16):10968-79. doi: 10.1074/jbc.M804923200. Epub 2009 Feb 25.


Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors.

Sitnicka E, Buza-Vidas N, Ahlenius H, Cilio CM, Gekas C, Nygren JM, Månsson R, Cheng M, Jensen CT, Svensson M, Leandersson K, Agace WW, Sigvardsson M, Jacobsen SE.

Blood. 2007 Oct 15;110(8):2955-64. Epub 2007 May 31.


Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.

Leandersson K, Riesbeck K, Andersson T.

Nucleic Acids Res. 2006;34(14):3988-99. Epub 2006 Aug 12.


Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.

Dejmek J, Säfholm A, Kamp Nielsen C, Andersson T, Leandersson K.

Mol Cell Biol. 2006 Aug;26(16):6024-36.


A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.

Säfholm A, Leandersson K, Dejmek J, Nielsen CK, Villoutreix BO, Andersson T.

J Biol Chem. 2006 Feb 3;281(5):2740-9. Epub 2005 Dec 5.


Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival.

Dejmek J, Leandersson K, Manjer J, Bjartell A, Emdin SO, Vogel WF, Landberg G, Andersson T.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):520-8.


p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils.

Alvarado-Kristensson M, Melander F, Leandersson K, Rönnstrand L, Wernstedt C, Andersson T.

J Exp Med. 2004 Feb 16;199(4):449-58.


Transforming growth factor-beta- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis.

Rosendahl A, Speletas M, Leandersson K, Ivars F, Sideras P.

Int Immunol. 2003 Dec;15(12):1401-14.


Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.

Dybedal I, Yang L, Bryder D, Aastrand-Grundstrom I, Leandersson K, Jacobsen SE.

Blood. 2003 Jul 1;102(1):118-26. Epub 2003 Mar 13.

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