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Items: 14


An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.

Barrett SE, Abrams MT, Burke R, Carr BA, Crocker LS, Garbaccio RM, Howell BJ, Kemp EA, Kowtoniuk RA, Latham AH, Leander KR, Leone AM, Patel M, Pechenov S, Pudvah NT, Riley S, Sepp-Lorenzino L, Walsh ES, Williams JM, Colletti SL.

Int J Pharm. 2014 May 15;466(1-2):58-67. doi: 10.1016/j.ijpharm.2014.03.011. Epub 2014 Mar 5.


Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics.

Parmar RG, Busuek M, Walsh ES, Leander KR, Howell BJ, Sepp-Lorenzino L, Kemp E, Crocker LS, Leone A, Kochansky CJ, Carr BA, Garbaccio RM, Colletti SL, Wang W.

Bioconjug Chem. 2013 Apr 17;24(4):640-7. doi: 10.1021/bc300600a. Epub 2013 Mar 25.


Androgen ablation augments human HLA2.1-restricted T cell responses to PSA self-antigen in transgenic mice.

Arredouani MS, Tseng-Rogenski SS, Hollenbeck BK, Escara-Wilke J, Leander KR, Defeo-Jones D, Hwang C, Sanda MG.

Prostate. 2010 Jun 15;70(9):1002-11. doi: 10.1002/pros.21134.


Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.

She QB, Chandarlapaty S, Ye Q, Lobo J, Haskell KM, Leander KR, DeFeo-Jones D, Huber HE, Rosen N.

PLoS One. 2008 Aug 26;3(8):e3065. doi: 10.1371/journal.pone.0003065.


Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.

DeFeo-Jones D, Barnett SF, Fu S, Hancock PJ, Haskell KM, Leander KR, McAvoy E, Robinson RG, Duggan ME, Lindsley CW, Zhao Z, Huber HE, Jones RE.

Mol Cancer Ther. 2005 Feb;4(2):271-9.


Induction of minisatellite DNA rearrangements by genotoxic carcinogens in mouse liver tumors.

Ledwith BJ, Joslyn DJ, Troilo P, Leander KR, Clair JH, Soper KA, Manam S, Prahalada S, van Zwieten MJ, Nichols WW.

Carcinogenesis. 1995 May;16(5):1167-72.


Dose-related changes in the profile of ras mutations in chemically induced CD-1 mouse liver tumors.

Manam S, Shinder GA, Joslyn DJ, Kraynak AR, Hammermeister CL, Leander KR, Ledwith BJ, Prahalada S, van Zwieten MJ, Nichols WW.

Carcinogenesis. 1995 May;16(5):1113-9.


Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors.

Montgomery DL, Shiver JW, Leander KR, Perry HC, Friedman A, Martinez D, Ulmer JB, Donnelly JJ, Liu MA.

DNA Cell Biol. 1993 Nov;12(9):777-83.


Targeted delivery of peptide epitopes to class I major histocompatibility molecules by a modified Pseudomonas exotoxin.

Donnelly JJ, Ulmer JB, Hawe LA, Friedman A, Shi XP, Leander KR, Shiver JW, Oliff AI, Martinez D, Montgomery D, et al.

Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3530-4.


Activation of the Ha-, Ki-, and N-ras genes in chemically induced liver tumors from CD-1 mice.

Manam S, Storer RD, Prahalada S, Leander KR, Kraynak AR, Ledwith BJ, van Zwieten MJ, Bradley MO, Nichols WW.

Cancer Res. 1992 Jun 15;52(12):3347-52.


Polymerase chain reaction/sequencing analysis of ras mutations in paraffin-embedded tissues as compared with 3T3 transfection and polymerase chain reaction/sequencing of frozen tumor deoxyribonucleic acids.

Goodrow TL, Prahalada SR, Storer RD, Manam SV, Leander KR, Kraynak AR, van Zwieten MJ, Nichols WW, Bradley MO.

Lab Invest. 1992 Apr;66(4):504-11.


Murine p53 intron sequences 5-8 and their use in polymerase chain reaction/direct sequencing analysis of p53 mutations in CD-1 mouse liver and lung tumors.

Goodrow TL, Storer RD, Leander KR, Prahalada SR, van Zwieten MJ, Bradley MO.

Mol Carcinog. 1992;5(1):9-15.


Activation of the Ki-ras gene in spontaneous and chemically induced lung tumors in CD-1 mice.

Manam S, Storer RD, Prahalada S, Leander KR, Kraynak AR, Hammermeister CL, Joslyn DJ, Ledwith BJ, van Zwieten MJ, Bradley MO, et al.

Mol Carcinog. 1992;6(1):68-75.


DNA fingerprinting of 7,12-dimethylbenz[a]anthracene-induced and spontaneous CD-1 mouse liver tumors.

Ledwith BJ, Storer RD, Prahalada S, Manam S, Leander KR, van Zwieten MJ, Nichols WW, Bradley MO.

Cancer Res. 1990 Sep 1;50(17):5245-9.

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