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Items: 1 to 50 of 58

1.

Effects of cortisol and lipopolysaccharide on expression of select growth-, stress- and immune-related genes in rainbow trout liver.

Shepherd BS, Spear AR, Philip AM, Leaman DW, Stepien CA, Sepulveda-Villet OJ, Palmquist DE, Vijayan MM.

Fish Shellfish Immunol. 2018 Mar;74:410-418. doi: 10.1016/j.fsi.2018.01.003. Epub 2018 Jan 8.

PMID:
29325711
2.

Role of Viral Hemorrhagic Septicemia Virus Matrix (M) Protein in Suppressing Host Transcription.

Ke Q, Weaver W, Pore A, Gorgoglione B, Wildschutte JH, Xiao P, Shepherd BS, Spear A, Malathi K, Stepien CA, Vakharia VN, Leaman DW.

J Virol. 2017 Sep 12;91(19). pii: e00279-17. doi: 10.1128/JVI.00279-17. Print 2017 Oct 1.

3.

Regulation of RANKL-induced osteoclastogenesis by RING finger protein RNF114.

Lin B, Ke Q, Leaman DW, Goel V, Agarwal A.

J Orthop Res. 2018 Jan;36(1):159-166. doi: 10.1002/jor.23654. Epub 2017 Jul 31.

4.

Intercellular adhesion molecule-1 augments myoblast adhesion and fusion through homophilic trans-interactions.

Pizza FX, Martin RA, Springer EM, Leffler MS, Woelmer BR, Recker IJ, Leaman DW.

Sci Rep. 2017 Jul 11;7(1):5094. doi: 10.1038/s41598-017-05283-3.

5.

Negative regulation of the RLH signaling by the E3 ubiquitin ligase RNF114.

Lin B, Ke Q, Li H, Pheifer NS, Velliquette DC, Leaman DW.

Cytokine. 2017 Nov;99:186-193. doi: 10.1016/j.cyto.2017.05.002. Epub 2017 Jul 29.

PMID:
28625874
6.

X-linked inhibitor of apoptosis-associated factor 1 regulates TNF receptor 1 complex stability.

Lin B, Xu D, Leaman DW.

FEBS Lett. 2016 Dec;590(23):4381-4392. doi: 10.1002/1873-3468.12467. Epub 2016 Nov 3.

7.

An aza-anthrapyrazole negatively regulates Th1 activity and suppresses experimental autoimmune encephalomyelitis.

Clark MP, Leaman DW, Hazelhurst LA, Hwang ES, Quinn A.

Int Immunopharmacol. 2016 Feb;31:74-87. doi: 10.1016/j.intimp.2015.12.014. Epub 2015 Dec 18.

PMID:
26709219
8.

Gene Diversification of an Emerging Pathogen: A Decade of Mutation in a Novel Fish Viral Hemorrhagic Septicemia (VHS) Substrain since Its First Appearance in the Laurentian Great Lakes.

Stepien CA, Pierce LR, Leaman DW, Niner MD, Shepherd BS.

PLoS One. 2015 Aug 27;10(8):e0135146. doi: 10.1371/journal.pone.0135146. eCollection 2015.

9.

Sustained release of small molecules from carbon nanotube-reinforced monetite calcium phosphate cement.

Lin B, Zhou H, Leaman DW, Goel VK, Agarwal AK, Bhaduri SB.

Mater Sci Eng C Mater Biol Appl. 2014 Oct;43:92-6. doi: 10.1016/j.msec.2014.06.027. Epub 2014 Jul 6.

PMID:
25175192
10.

A new StaRT-PCR approach to detect and quantify fish Viral Hemorrhagic Septicemia virus (VHSv): enhanced quality control with internal standards.

Pierce LR, Willey JC, Crawford EL, Palsule VV, Leaman DW, Faisal M, Kim RK, Shepherd BS, Stanoszek LM, Stepien CA.

J Virol Methods. 2013 Apr;189(1):129-42. doi: 10.1016/j.jviromet.2013.01.006. Epub 2013 Jan 30.

PMID:
23375747
11.

Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection.

Rosebeck S, Sudini K, Chen T, Leaman DW.

Virology. 2011 Sep 1;417(2):293-303. doi: 10.1016/j.virol.2011.06.010. Epub 2011 Jul 13.

12.

Emerging roles of FAM14 family members (G1P3/ISG 6-16 and ISG12/IFI27) in innate immunity and cancer.

Cheriyath V, Leaman DW, Borden EC.

J Interferon Cytokine Res. 2011 Jan;31(1):173-81. doi: 10.1089/jir.2010.0105. Epub 2010 Oct 12. Review.

13.

Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes.

Vyas K, Chaudhuri S, Leaman DW, Komar AA, Musiyenko A, Barik S, Mazumder B.

Mol Cell Biol. 2009 Jan;29(2):458-70. doi: 10.1128/MCB.00824-08. Epub 2008 Nov 10.

14.

Identification of interferon-beta-stimulated genes that inhibit angiogenesis in vitro.

Taylor KL, Leaman DW, Grane R, Mechti N, Borden EC, Lindner DJ.

J Interferon Cytokine Res. 2008 Dec;28(12):733-40. doi: 10.1089/jir.2008.0030.

PMID:
18937547
15.

Recent progress in oligonucleotide therapeutics: antisense to aptamers.

Leaman DW.

Expert Opin Drug Discov. 2008 Sep;3(9):997-1009. doi: 10.1517/17460441.3.9.997.

PMID:
23506176
16.

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a.

Rosebeck S, Leaman DW.

Apoptosis. 2008 Apr;13(4):562-72. doi: 10.1007/s10495-008-0190-0.

PMID:
18330707
17.

Lumbar ligamentum flavum hypertrophy is due to accumulation of inflammation-related scar tissue.

Sairyo K, Biyani A, Goel VK, Leaman DW, Booth R Jr, Thomas J, Ebraheim NA, Cowgill IA, Mohan SE.

Spine (Phila Pa 1976). 2007 May 15;32(11):E340-7.

PMID:
17495768
18.

Microarray analysis of nitric oxide responsive transcripts in Arabidopsis.

Parani M, Rudrabhatla S, Myers R, Weirich H, Smith B, Leaman DW, Goldman SL.

Plant Biotechnol J. 2004 Jul;2(4):359-66.

19.

Human telomerase RNA degradation by 2'-5'-linked oligoadenylate antisense chimeras in a cell-free system, cultured tumor cells, and murine xenograft models.

Paranjape JM, Xu D, Kushner DM, Okicki J, Lindner DJ, Cramer H, Silverman RH, Leaman DW.

Oligonucleotides. 2006 Fall;16(3):225-38.

PMID:
16978086
20.

Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.

Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC.

J Clin Oncol. 2006 Aug 10;24(23):3771-9. Epub 2006 Jun 26.

PMID:
16801630
21.

Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse.

Mohammad MK, Morran M, Slotterbeck B, Leaman DW, Sun Y, Grafenstein Hv, Hong SC, McInerney MF.

Int Immunol. 2006 Jul;18(7):1101-13. Epub 2006 May 25. Erratum in: Int Immunol. 2007 Apr;19(4):581.

PMID:
16728431
22.

IFN-alpha1,8 inhibits tumor-induced angiogenesis in murine angiosarcomas.

Taylor KL, Oates RK, Grane R, Leaman DW, Borden EC, Lindner DJ.

J Interferon Cytokine Res. 2006 May;26(5):353-61.

PMID:
16689662
23.

Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons.

Reu FJ, Leaman DW, Maitra RR, Bae SI, Cherkassky L, Fox MW, Rempinski DR, Beaulieu N, MacLeod AR, Borden EC.

Cancer Res. 2006 Mar 1;66(5):2785-93.

24.

2-5A antisense treatment of respiratory syncytial virus.

Leaman DW.

Curr Opin Pharmacol. 2005 Oct;5(5):502-7. Review.

PMID:
16081320
25.

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection.

Sun Y, Leaman DW.

J Biol Chem. 2005 Apr 22;280(16):15561-8. Epub 2005 Feb 10.

26.

Regulation of gene expression by pegylated IFN-alpha2b and IFN-alpha2b in human peripheral blood mononuclear cells.

Brassard DL, Delorenzo MM, Cox S, Leaman DW, Sun Y, Ding W, Gavor S, Spond J, Goodsaid F, Bordens R, Grace MJ.

J Interferon Cytokine Res. 2004 Aug;24(8):455-69.

PMID:
15320959
27.
28.

Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice.

Sarkar S, Leaman DW, Gupta S, Sil P, Young D, Morehead A, Mukherjee D, Ratliff N, Sun Y, Rayborn M, Hollyfield J, Sen S.

J Biol Chem. 2004 May 7;279(19):20422-34. Epub 2004 Feb 16.

29.

Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.

Leaman DW, Chawla-Sarkar M, Jacobs B, Vyas K, Sun Y, Ozdemir A, Yi T, Williams BR, Borden EC.

J Interferon Cytokine Res. 2003 Dec;23(12):745-56.

PMID:
14769151
30.

Biologic activity of polyethylene glycol12000-interferon-alpha2b compared with interferon-alpha2b: gene modulatory and antigrowth effects in tumor cells.

Vyas K, Brassard DL, DeLorenzo MM, Sun Y, Grace MJ, Borden EC, Leaman DW.

J Immunother. 2003 May-Jun;26(3):202-11.

PMID:
12806274
31.

IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis.

Chawla-Sarkar M, Leaman DW, Jacobs BS, Borden EC.

J Immunol. 2002 Jul 15;169(2):847-55.

32.

Resistance to interferons in melanoma cells does not correlate with the expression or activation of signal transducer and activator of transcription 1 (Stat1).

Chawla-Sarkar M, Leaman DW, Jacobs BS, Tuthill RJ, Chatterjee-Kishore M, Stark GR, Borden EC.

J Interferon Cytokine Res. 2002 May;22(5):603-13.

PMID:
12060499
33.

Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis.

Leaman DW, Chawla-Sarkar M, Vyas K, Reheman M, Tamai K, Toji S, Borden EC.

J Biol Chem. 2002 Aug 9;277(32):28504-11. Epub 2002 May 23.

34.

Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense.

Leaman DW, Longano FJ, Okicki JR, Soike KF, Torrence PF, Silverman RH, Cramer H.

Virology. 2002 Jan 5;292(1):70-7.

37.

2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells.

Kushner DM, Paranjape JM, Bandyopadhyay B, Cramer H, Leaman DW, Kennedy AW, Silverman RH, Cowell JK.

Gynecol Oncol. 2000 Feb;76(2):183-92.

PMID:
10637068
38.
39.

Controlling gene expression with 2-5A antisense.

Leaman DW, Cramer H.

Methods. 1999 Jul;18(3):252-65. Review.

PMID:
10454983
40.

Mechanisms of interferon action.

Leaman DW.

Prog Mol Subcell Biol. 1998;20:101-42. Review. No abstract available.

PMID:
9928528
41.

A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes.

Leaman DW, Salvekar A, Patel R, Sen GC, Stark GR.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9442-7.

42.

The antiproliferative and antiviral activities of IFN-tau variants in human cells.

Alexenko AP, Leaman DW, Li J, Roberts RM.

J Interferon Cytokine Res. 1997 Dec;17(12):769-79.

PMID:
9452365
43.

Regulation of STAT-dependent pathways by growth factors and cytokines.

Leaman DW, Leung S, Li X, Stark GR.

FASEB J. 1996 Dec;10(14):1578-88. Review.

PMID:
9002549
44.

The interferon-tau genes of the giraffe, a nonbovid species.

Liu L, Leaman DW, Roberts RM.

J Interferon Cytokine Res. 1996 Nov;16(11):949-51.

PMID:
8938571
45.
46.

Participation of JAK and STAT proteins in growth hormone-induced signaling.

Han Y, Leaman DW, Watling D, Rogers NC, Groner B, Kerr IM, Wood WI, Stark GR.

J Biol Chem. 1996 Mar 8;271(10):5947-52.

47.

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor.

Leaman DW, Pisharody S, Flickinger TW, Commane MA, Schlessinger J, Kerr IM, Levy DE, Stark GR.

Mol Cell Biol. 1996 Jan;16(1):369-75.

48.
49.

Insulin-like growth-factor binding protein (IGFBP) serum levels and hepatic IGFBP-2 and -3 mRNA expression in diabetic and insulin-treated swine (Sus scrofa).

White ME, Leaman DW, Ramsay TG, Kampman KA, Ernst CW, Osborne JM.

Comp Biochem Physiol B. 1993 Oct;106(2):341-7.

PMID:
7694822
50.

Interferons as hormones of pregnancy.

Roberts RM, Cross JC, Leaman DW.

Endocr Rev. 1992 Aug;13(3):432-52. Review. No abstract available.

PMID:
1385108

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