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Ecological response to altered rainfall differs across the Neotropics.

Srivastava DS, Céréghino R, Trzcinski MK, MacDonald AAM, Marino NAC, Acosta Mercado D, Leroy C, Corbara B, Romero GQ, Farjalla VF, Barberis IM, Dézerald O, Hammill E, Atwood TB, Piccoli GCO, Ospina Bautista F, Carrias JF, Leal JS, Montero G, Antiqueira PAP, Freire R, Realpe E, Amundrud SL, de Omena PM, Campos ABA.

Ecology. 2020 Jan 20:e02984. doi: 10.1002/ecy.2984. [Epub ahead of print]


Enhanced recovery following hip and knee arthroplasty: a systematic review of cost-effectiveness evidence.

Pritchard MG, Murphy J, Cheng L, Janarthanan R, Judge A, Leal J.

BMJ Open. 2020 Jan 15;10(1):e032204. doi: 10.1136/bmjopen-2019-032204.


A Matter of Perspective: An Exploratory Study of a Theory of Mind Autism Intervention for Adolescents.

Lecheler M, Lasser J, Vaughan PW, Leal J, Ordetx K, Bischofberger M.

Psychol Rep. 2020 Jan 10:33294119898120. doi: 10.1177/0033294119898120. [Epub ahead of print] No abstract available.


Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): study protocol for a patient-blinded, randomised controlled superiority trial of liposomal bupivacaine.

Knight R, Poulton L, Strickland LH, Hamilton TW, Beard D, Cook J, Dutton SJ, Leal J, Lamb S, Cooper C, Barker KL, Murray DW, Pandit HG.

Trials. 2019 Dec 16;20(1):732. doi: 10.1186/s13063-019-3826-1.


Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii.

Dalvie NC, Leal J, Whittaker CA, Yang Y, Brady JR, Love KR, Love JC.

ACS Synth Biol. 2020 Jan 17;9(1):26-35. doi: 10.1021/acssynbio.9b00372. Epub 2019 Dec 13.


Ionizing Radiation for Preparation and Functionalization of Membranes and Their Biomedical and Environmental Applications.

Casimiro MH, Ferreira LM, Leal JP, Pereira CCL, Monteiro B.

Membranes (Basel). 2019 Dec 3;9(12). pii: E163. doi: 10.3390/membranes9120163. Review.


Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

Reed SD, Li Y, Dakin HA, Becker F, Leal J, Gustavson SM, Kartman B, Wittbrodt E, Mentz RJ, Pagidipati NJ, Bethel MA, Gray AM, Holman RR, Hernandez AF; EXSCEL Study Group.

Diabetes Care. 2019 Dec 5. pii: dc190950. doi: 10.2337/dc19-0950. [Epub ahead of print]


Assessment on patient outcomes of primary hip replacement: an interrupted time series analysis from 'The National Joint Registry of England and Wales'.

Garriga C, Murphy J, Leal J, Arden NK, Price AJ, Prieto-Alhambra D, Carr AJ, Rangan A, Cooper C, Peat G, Fitzpatrick R, Barker KL, Judge A.

BMJ Open. 2019 Nov 21;9(11):e031599. doi: 10.1136/bmjopen-2019-031599.


Hospital-acquired Clostridioides difficile infections in Alberta: The validity of laboratory-identified event surveillance versus clinical infection surveillance.

Almond J, Leal J, Bush K, Rogers E, Henderson EA, Ellison J.

Am J Infect Control. 2019 Nov 13. pii: S0196-6553(19)30891-0. doi: 10.1016/j.ajic.2019.09.029. [Epub ahead of print]


Limited Diclosulam Herbicide Uptake and Translocation-Induced Tolerance in Crotalaria juncea.

de Souza CDCB, Borella J, Leal JFL, Tornisielo VL, Pimpinato RF, Monquero PA, de Pinho CF.

Bull Environ Contam Toxicol. 2020 Jan;104(1):114-120. doi: 10.1007/s00128-019-02742-7. Epub 2019 Nov 13.


Physiotherapy rehabilitation for osteoporotic vertebral fracture-a randomised controlled trial and economic evaluation (PROVE trial).

Barker KL, Newman M, Stallard N, Leal J, Lowe CM, Javaid MK, Noufaily A, Hughes T, Smith D, Gandhi V, Cooper C, Lamb SE; PROVE trial group.

Osteoporos Int. 2019 Nov 12. doi: 10.1007/s00198-019-05133-0. [Epub ahead of print]


New lake in a changing world: the construction and filling of a small hydropower reservoir in the tropics (Rio de Janeiro, Brazil).

Branco CWC, Leal JJF, Huszar VLM, Farias DDS, Saint'Pierre TD, Sousa-Filho IF, de Palermo EFA, Guarino AWS, Gomes AR, Kozlowsky-Suzuki B.

Environ Sci Pollut Res Int. 2019 Dec;26(35):36007-36022. doi: 10.1007/s11356-019-06665-y. Epub 2019 Nov 11.


Multi-species okadaic acid contamination and human poisoning during a massive bloom of Dinophysis acuminata complex in southern Brazil.

Mafra LL Jr, Nolli PKW, Mota LE, Domit C, Soeth M, Luz LFG, Sobrinho BF, Leal JG, Di Domenico M.

Harmful Algae. 2019 Nov;89:101662. doi: 10.1016/j.hal.2019.101662. Epub 2019 Sep 20.


Geographical Variation in Outcomes of Primary Hip and Knee Replacement.

Garriga C, Leal J, Sánchez-Santos MT, Arden N, Price A, Prieto-Alhambra D, Carr A, Rangan A, Cooper C, Peat G, Fitzpatrick R, Barker K, Judge A.

JAMA Netw Open. 2019 Oct 2;2(10):e1914325. doi: 10.1001/jamanetworkopen.2019.14325.


Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment.

Mohanty RP, Liu X, Kim JY, Peng X, Bhandari S, Leal J, Arasappan D, Wylie DC, Dong T, Ghosh D.

Nanoscale. 2019 Oct 3;11(38):17664-17681. doi: 10.1039/c9nr05783h.


Cognitive and motor effects of Kinect-based games training in people with and without Parkinson disease: A preliminary study.

de Melo Cerqueira TM, de Moura JA, de Lira JO, Leal JC, D'Amelio M, do Santos Mendes FA.

Physiother Res Int. 2020 Jan;25(1):e1807. doi: 10.1002/pri.1807. Epub 2019 Aug 29.


Automated virtual reality (VR) cognitive therapy for patients with psychosis: study protocol for a single-blind parallel group randomised controlled trial (gameChange).

Freeman D, Yu LM, Kabir T, Martin J, Craven M, Leal J, Lambe S, Brown S, Morrison A, Chapman K, Dudley R, O'Regan E, Rovira A, Goodsell A, Rosebrock L, Bergin A, Cryer TL, Robotham D, Andleeb H, Geddes JR, Hollis C, Clark DM, Waite F.

BMJ Open. 2019 Aug 27;9(8):e031606. doi: 10.1136/bmjopen-2019-031606.


Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture: three-arm PROVE RCT.

Barker KL, Newman M, Stallard N, Leal J, Minns Lowe C, Javaid MK, Noufaily A, Adhikari A, Hughes T, Smith DJ, Gandhi V, Cooper C, Lamb SE.

Health Technol Assess. 2019 Aug;23(44):1-318. doi: 10.3310/hta23440.


MPMT-OX up-regulates GABAergic transmission and protects against seizure-like behavior in Caenorhabditis elegans.

Câmara DF, Machado ML, Arantes LP, Silva TC, Silveira TL, Leal JG, Dornelles L, Stefanello ST, Soares FAA.

Neurotoxicology. 2019 Sep;74:272-281. doi: 10.1016/j.neuro.2019.08.001. Epub 2019 Aug 12.


Imager-4D: New Software for Viewing Dynamic PET Scans and Extracting Radiomic Parameters from PET Data.

Rowe SP, Solnes LB, Yin Y, Kitchen G, Lodge MA, Karakatsanis NA, Rahmim A, Pomper MG, Leal JP.

J Digit Imaging. 2019 Dec;32(6):1071-1080. doi: 10.1007/s10278-019-00255-7.


The Challenge of Transparency and Validation in Health Economic Decision Modelling: A View from Mount Hood.

Kent S, Becker F, Feenstra T, Tran-Duy A, Schlackow I, Tew M, Zhang P, Ye W, Lizheng S, Herman W, McEwan P, Schramm W, Gray A, Leal J, Lamotte M, Willis M, Palmer AJ, Clarke P.

Pharmacoeconomics. 2019 Nov;37(11):1305-1312. doi: 10.1007/s40273-019-00825-1.


Impact of aging on semiquantitative uptake parameters in normal rated clinical baseline [123I]Ioflupane single photon emission computed tomography/computed tomography.

Werner RA, Lapa C, Sheikhbahaei S, Marcus C, Solnes LB, Du Y, Leal JP, Buck AK, Higuchi T, Rowe SP, Javadi MS.

Nucl Med Commun. 2019 Oct;40(10):1001-1004. doi: 10.1097/MNM.0000000000001061.


Attributable costs and length of stay of hospital-acquired Clostridioides difficile: A population-based matched cohort study in Alberta, Canada.

Leal JR, Conly J, Weaver R, Wick J, Henderson EA, Manns B, Ronksley P.

Infect Control Hosp Epidemiol. 2019 Oct;40(10):1135-1143. doi: 10.1017/ice.2019.178. Epub 2019 Jul 25.


The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.

Beard DJ, Davies LJ, Cook JA, MacLennan G, Price A, Kent S, Hudson J, Carr A, Leal J, Campbell H, Fitzpatrick R, Arden N, Murray D, Campbell MK; TOPKAT Study Group.

Lancet. 2019 Aug 31;394(10200):746-756. doi: 10.1016/S0140-6736(19)31281-4. Epub 2019 Jul 17.


Impact of achieving primary care targets in type 2 diabetes on health outcomes and healthcare costs.

Keng MJ, Tsiachristas A, Leal J, Gray A, Mihaylova B.

Diabetes Obes Metab. 2019 Nov;21(11):2405-2412. doi: 10.1111/dom.13821. Epub 2019 Jul 21.


Successful organ donation for transplantation: Targeted actions in the emergency department.

Caballero F, Puig M, Leal J, Trejo O, Díaz I, Herrera S, Turbau M, Ris J, Benito S.

Am J Transplant. 2019 Oct;19(10):2960-2961. doi: 10.1111/ajt.15516. Epub 2019 Jul 18. No abstract available.


Unravelling the Role of MAPKs (ERK1/2) in Venous Reflux in Patients with Chronic Venous Disorder.

Ortega MA, Asúnsolo Á, Romero B, Álvarez-Rocha MJ, Sainz F, Leal J, Álvarez-Mon M, Buján J, García-Honduvilla N.

Cells Tissues Organs. 2018;206(4-5):272-282. doi: 10.1159/000500449. Epub 2019 Jun 14.


Breeding objectives of Brangus cattle in Brazil.

Simões MRS, Leal JJB, Minho AP, Gomes CC, MacNeil MD, Costa RF, Junqueira VS, Schmidt PI, Cardoso FF, Boligon AA, Yokoo MJ.

J Anim Breed Genet. 2019 Jun 10. doi: 10.1111/jbg.12415. [Epub ahead of print]


Impact of a national enhanced recovery after surgery programme on patient outcomes of primary total knee replacement: an interrupted time series analysis from "The National Joint Registry of England, Wales, Northern Ireland and the Isle of Man".

Garriga C, Murphy J, Leal J, Price A, Prieto-Alhambra D, Carr A, Arden NK, Rangan A, Cooper C, Peat G, Fitzpatrick R, Barker K, Judge A.

Osteoarthritis Cartilage. 2019 Sep;27(9):1280-1293. doi: 10.1016/j.joca.2019.05.001. Epub 2019 May 10.


The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study.

Paranjpe MD, Chen X, Liu M, Paranjpe I, Leal JP, Wang R, Pomper MG, Wong DF, Benzinger TLS, Zhou Y; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2019;22:101795. doi: 10.1016/j.nicl.2019.101795. Epub 2019 Mar 28.


Predictors of mortality and length of stay in patients with hospital-acquired Clostridioides difficile infection: a population-based study in Alberta, Canada.

Leal J, Ronksley P, Henderson EA, Conly J, Manns B.

J Hosp Infect. 2019 Sep;103(1):85-91. doi: 10.1016/j.jhin.2019.04.007. Epub 2019 Apr 13.


Taste disorders following cancer treatment: report of a case series.

Epstein JB, de Andrade E Silva SM, Epstein GL, Leal JHS, Barasch A, Smutzer G.

Support Care Cancer. 2019 Dec;27(12):4587-4595. doi: 10.1007/s00520-019-04758-5. Epub 2019 Mar 29.


Checkpoint Blockade Strategies in the Treatment of Breast Cancer: Where We Are and Where We Are Heading.

Force J, Leal JHS, McArthur HL.

Curr Treat Options Oncol. 2019 Mar 28;20(4):35. doi: 10.1007/s11864-019-0634-5. Review.


Association of PET-measured myocardial flow reserve with echocardiography-estimated pulmonary artery systolic pressure in patients with hypertrophic cardiomyopathy.

Zhao M, Liu M, Leal JP, Tsui BMW, Wong DF, Pomper MG, Zhou Y.

PLoS One. 2019 Mar 20;14(3):e0212573. doi: 10.1371/journal.pone.0212573. eCollection 2019.


Correction to: The Impact of Hospital Costing Methods on Cost-Effectiveness Analysis: A Case Study.

Leal J, Manetti S, Buchanan J.

Pharmacoeconomics. 2019 Jun;37(6):867. doi: 10.1007/s40273-018-00764-3.


Decision models of prediabetes populations: A systematic review.

Leal J, Morrow LM, Khurshid W, Pagano E, Feenstra T.

Diabetes Obes Metab. 2019 Jul;21(7):1558-1569. doi: 10.1111/dom.13684. Epub 2019 Apr 1.


Nudging people with Type 2 diabetes towards better self-management through personalized risk communication: A pilot randomized controlled trial in primary care.

Rouyard T, Leal J, Baskerville R, Velardo C, Salvi D, Gray A.

Endocrinol Diabetes Metab. 2018 Jun 22;1(3):e00022. doi: 10.1002/edm2.22. eCollection 2018 Jul.


In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression.

Rychlik KA, Secrest JR, Lau C, Pulczinski J, Zamora ML, Leal J, Langley R, Myatt LG, Raju M, Chang RC, Li Y, Golding MC, Rodrigues-Hoffmann A, Molina MJ, Zhang R, Johnson NM.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3443-3448. doi: 10.1073/pnas.1816103116. Epub 2019 Feb 11.


The Correlation Between [68Ga]DOTATATE PET/CT and Cell Proliferation in Patients With GEP-NENs.

Yu J, Li N, Li J, Lu M, Leal JP, Tan H, Su H, Fan Y, Zhang Y, Zhao W, Zhu H, Pomper MG, Zhou Y, Yang Z.

Mol Imaging Biol. 2019 Oct;21(5):984-990. doi: 10.1007/s11307-019-01328-3.


Novel Functional Renal PET Imaging With 18F-FDS in Human Subjects.

Werner RA, Ordonez AA, Sanchez-Bautista J, Marcus C, Lapa C, Rowe SP, Pomper MG, Leal JP, Lodge MA, Javadi MS, Jain SK, Higuchi T.

Clin Nucl Med. 2019 May;44(5):410-411. doi: 10.1097/RLU.0000000000002494.


Non-ionizing method of screening adolescent idiopathic scoliosis in schoolchildren.

Aroeira RMC, Leal JS, Pertence AEM, Casas EBL, Greco M.

Cien Saude Colet. 2019 Feb;24(2):523-534. doi: 10.1590/1413-81232018242.12882017. Portuguese, English.


TBCRC026: Phase II Trial Correlating Standardized Uptake Value With Pathologic Complete Response to Pertuzumab and Trastuzumab in Breast Cancer.

Connolly RM, Leal JP, Solnes L, Huang CY, Carpenter A, Gaffney K, Abramson V, Carey LA, Liu MC, Rimawi M, Specht J, Storniolo AM, Valero V, Vaklavas C, Krop IE, Winer EP, Camp M, Miller RS, Wolff AC, Cimino-Mathews A, Park BH, Wahl RL, Stearns V.

J Clin Oncol. 2019 Mar 20;37(9):714-722. doi: 10.1200/JCO.2018.78.7986. Epub 2019 Feb 5.


Accuracy of photogrammetry for detecting adolescent idiopathic scoliosis progression.

Leal JS, Aroeira RMC, Gressler V, Greco M, Pertence AEM, Lamounier JA.

Spine J. 2019 Feb;19(2):321-329. doi: 10.1016/j.spinee.2018.06.362. Epub 2018 Jul 6.


Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.

Lynn GM, Chytil P, Francica JR, Lagová A, Kueberuwa G, Ishizuka AS, Zaidi N, Ramirez-Valdez RA, Blobel NJ, Baharom F, Leal J, Wang AQ, Gerner MY, Etrych T, Ulbrich K, Seymour LW, Seder RA, Laga R.

Biomacromolecules. 2019 Feb 11;20(2):854-870. doi: 10.1021/acs.biomac.8b01473. Epub 2019 Jan 22.


Chitosan/Poly(vinylpyrrolidone) Matrices Obtained by Gamma-Irradiation for Skin Scaffolds: Characterization and Preliminary Cell Response Studies.

Casimiro MH, Gomes SR, Rodrigues G, Leal JP, Ferreira LM.

Materials (Basel). 2018 Dec 13;11(12). pii: E2535. doi: 10.3390/ma11122535.


Cost-effectiveness of digital surveillance clinics with optical coherence tomography versus hospital eye service follow-up for patients with screen-positive maculopathy.

Leal J, Luengo-Fernandez R, Stratton IM, Dale A, Ivanova K, Scanlon PH.

Eye (Lond). 2019 Apr;33(4):640-647. doi: 10.1038/s41433-018-0297-7. Epub 2018 Nov 30.


Regorafenib adjusted dose for Chilean patients with chemoresistant metastatic colorectal cancer: a case series.

Leal JL, Briones J, Herrera ME, Müller B, Nervi B, Mondaca S.

Ecancermedicalscience. 2018 Oct 2;12:875. doi: 10.3332/ecancer.2018.875. eCollection 2018.


l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats.

Leal J, Teixeira-Santos L, Pinho D, Afonso J, Carvalho J, de Lourdes Bastos M, Albino-Teixeira A, Fraga S, Sousa T.

Nitric Oxide. 2019 Jan 1;82:1-11. doi: 10.1016/j.niox.2018.10.007. Epub 2018 Nov 10.


Impact of Tumor Burden on Quantitative [68Ga] DOTATOC Biodistribution.

Werner RA, Hänscheid H, Leal JP, Javadi MS, Higuchi T, Lodge MA, Buck AK, Pomper MG, Lapa C, Rowe SP.

Mol Imaging Biol. 2019 Aug;21(4):790-798. doi: 10.1007/s11307-018-1293-9.


Strong Influence of Ancillary Ligands Containing Benzothiazole or Benzimidazole Rings on Cytotoxicity and Photoactivation of Ru(II) Arene Complexes.

Lari M, Martínez-Alonso M, Busto N, Manzano BR, Rodríguez AM, Acuña MI, Domínguez F, Albasanz JL, Leal JM, Espino G, García B.

Inorg Chem. 2018 Nov 19;57(22):14322-14336. doi: 10.1021/acs.inorgchem.8b02299. Epub 2018 Oct 31.


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