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Items: 1 to 50 of 72

1.

Single-organelle quantification reveals the stoichiometric and structural variability of carboxysomes dependent on the environment.

Sun Y, Wollman A, Huang F, Leake M, Liu L.

Plant Cell. 2019 May 2. pii: tpc.00787.2018. doi: 10.1105/tpc.18.00787. [Epub ahead of print]

2.

Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome.

Syeda AH, Wollman AJM, Hargreaves AL, Howard JAL, Br√ľning JG, McGlynn P, Leake MC.

Nucleic Acids Res. 2019 Apr 27. pii: gkz298. doi: 10.1093/nar/gkz298. [Epub ahead of print]

PMID:
31028385
3.

Correction: Transcription factor clusters regulate genes in eukaryotic cells.

Wollman AJ, Shashkova S, Hedlund EG, Friemann R, Hohmann S, Leake MC.

Elife. 2019 Feb 6;8. pii: e45804. doi: 10.7554/eLife.45804.

4.

Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration.

Haapasalo K, Wollman AJM, de Haas CJC, van Kessel KPM, van Strijp JAG, Leake MC.

FASEB J. 2019 Mar;33(3):3807-3824. doi: 10.1096/fj.201801910R. Epub 2018 Dec 3.

5.

ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic Tolerance.

Pu Y, Li Y, Jin X, Tian T, Ma Q, Zhao Z, Lin SY, Chen Z, Li B, Yao G, Leake MC, Lo CJ, Bai F.

Mol Cell. 2019 Jan 3;73(1):143-156.e4. doi: 10.1016/j.molcel.2018.10.022. Epub 2018 Nov 21.

PMID:
30472191
6.

Single-molecule imaging of DNA gyrase activity in living Escherichia coli.

Stracy M, Wollman AJM, Kaja E, Gapinski J, Lee JE, Leek VA, McKie SJ, Mitchenall LA, Maxwell A, Sherratt DJ, Leake MC, Zawadzki P.

Nucleic Acids Res. 2019 Jan 10;47(1):210-220. doi: 10.1093/nar/gky1143.

8.

High-Speed Single-Molecule Tracking of CXCL13 in the B-Follicle.

Miller H, Cosgrove J, Wollman AJM, Taylor E, Zhou Z, O'Toole PJ, Coles MC, Leake MC.

Front Immunol. 2018 May 22;9:1073. doi: 10.3389/fimmu.2018.01073. eCollection 2018.

9.

The case for biophysics super-groups in physics departments.

Hoogenboom BW, Leake MC.

Phys Biol. 2018 Jul 6;15(6):060201. doi: 10.1088/1478-3975/aaca0a.

PMID:
29863490
10.

Molecular coordination of Staphylococcus aureus cell division.

Lund VA, Wacnik K, Turner RD, Cotterell BE, Walther CG, Fenn SJ, Grein F, Wollman AJ, Leake MC, Olivier N, Cadby A, Mesnage S, Jones S, Foster SJ.

Elife. 2018 Feb 21;7. pii: e32057. doi: 10.7554/eLife.32057.

11.

Characterising Maturation of GFP and mCherry of Genomically Integrated Fusions in Saccharomyces cerevisiae.

Shashkova S, Wollman AJ, Hohmann S, Leake MC.

Bio Protoc. 2018 Jan 20;8(2):e2710. doi: 10.21769/BioProtoc.2710.

12.

Corrigendum to "Single-molecule in vivo imaging of bacterial respiratory complexes indicates delocalized oxidative phosphorylation" [Biochim. Biophys. Acta 1837(6) (2014) 811-824 DOI: 10.1016/j.bbabio.2014.01.020].

Llorente-Garcia I, Lenn T, Erhardt H, Harriman OL, Liu LN, Robson A, Chiu SW, Matthews S, Willis NJ, Bray CD, Lee SH, Shin JY, Bustamante C, Liphardt J, Friedrich T, Mullineaux CW, Leake MC.

Biochim Biophys Acta Bioenerg. 2018 Feb;1859(2):164. doi: 10.1016/j.bbabio.2017.11.005. Epub 2017 Nov 22. No abstract available.

13.

Single-molecule techniques in biophysics: a review of the progress in methods and applications.

Miller H, Zhou Z, Shepherd J, Wollman AJM, Leake MC.

Rep Prog Phys. 2018 Feb;81(2):024601. doi: 10.1088/1361-6633/aa8a02.

PMID:
28869217
14.

The yeast Mig1 transcriptional repressor is dephosphorylated by glucose-dependent and -independent mechanisms.

Shashkova S, Wollman AJM, Leake MC, Hohmann S.

FEMS Microbiol Lett. 2017 Aug 1;364(14). doi: 10.1093/femsle/fnx133.

PMID:
28854669
15.

Transcription factor clusters regulate genes in eukaryotic cells.

Wollman AJ, Shashkova S, Hedlund EG, Friemann R, Hohmann S, Leake MC.

Elife. 2017 Aug 25;6. pii: e27451. doi: 10.7554/eLife.27451. Erratum in: Elife. 2019 Feb 06;8:.

16.

Imaging the cell.

Carrascosa JL, Leake MC.

Biophys Rev. 2017 Aug;9(4):295-296. doi: 10.1007/s12551-017-0280-8. Epub 2017 Aug 3. No abstract available.

17.

Single-molecule fluorescence microscopy review: shedding new light on old problems.

Shashkova S, Leake MC.

Biosci Rep. 2017 Jul 21;37(4). pii: BSR20170031. doi: 10.1042/BSR20170031. Print 2017 Aug 31. Review.

18.

An experimental study of the putative mechanism of a synthetic autonomous rotary DNA nanomotor.

Dunn KE, Leake MC, Wollman AJ, Trefzer MA, Johnson S, Tyrrell AM.

R Soc Open Sci. 2017 Mar 22;4(3):160767. doi: 10.1098/rsos.160767. eCollection 2017 Mar.

19.

Frequent exchange of the DNA polymerase during bacterial chromosome replication.

Beattie TR, Kapadia N, Nicolas E, Uphoff S, Wollman AJ, Leake MC, Reyes-Lamothe R.

Elife. 2017 Mar 31;6. pii: e21763. doi: 10.7554/eLife.21763.

21.

Biophysics of Infection. Preface.

Leake MC.

Adv Exp Med Biol. 2016;915:v. No abstract available.

PMID:
27532078
22.

Using Fluorescence Recovery After Photobleaching (FRAP) to Study Dynamics of the Structural Maintenance of Chromosome (SMC) Complex In Vivo.

Badrinarayanan A, Leake MC.

Methods Mol Biol. 2016;1431:37-46. doi: 10.1007/978-1-4939-3631-1_4.

PMID:
27283300
23.

Single-Molecule Narrow-Field Microscopy of Protein-DNA Binding Dynamics in Glucose Signal Transduction of Live Yeast Cells.

Wollman AJ, Leake MC.

Methods Mol Biol. 2016;1431:5-15. doi: 10.1007/978-1-4939-3631-1_2.

PMID:
27283298
24.

New Advances in Chromosome Architecture.

Leake MC.

Methods Mol Biol. 2016;1431:1-3. doi: 10.1007/978-1-4939-3631-1_1.

PMID:
27283297
25.

Force Spectroscopy in Studying Infection.

Zhou Z, Leake MC.

Adv Exp Med Biol. 2016;915:307-27. doi: 10.1007/978-3-319-32189-9_19. Review.

PMID:
27193551
26.

Designing a Single-Molecule Biophysics Tool for Characterising DNA Damage for Techniques that Kill Infectious Pathogens Through DNA Damage Effects.

Miller H, Wollman AJ, Leake MC.

Adv Exp Med Biol. 2016;915:115-27. doi: 10.1007/978-3-319-32189-9_9. Review.

PMID:
27193541
27.

Single-Molecule Observation of DNA Replication Repair Pathways in E. coli.

Wollman AJ, Syeda AH, McGlynn P, Leake MC.

Adv Exp Med Biol. 2016;915:5-16. doi: 10.1007/978-3-319-32189-9_2. Review.

PMID:
27193534
28.

The Biophysics of Infection.

Leake MC.

Adv Exp Med Biol. 2016;915:1-3. doi: 10.1007/978-3-319-32189-9_1.

PMID:
27193533
29.

Plasmonics, Tracking and Manipulating, and Living Cells: general discussion.

Cordes T, Moerner W, Orrit M, Sekatskii S, Faez S, Borri P, Prabal Goswami H, Clark A, El-Khoury P, Mayr S, Mika J, Lyu G, Cross D, Balzarotti F, Langbein W, Sandoghdar V, Michaelis J, Chowdhury A, Meixner AJ, van Hulst N, Lounis B, Stefani F, Cichos F, Dahan M, Novotny L, Leake M, Yang H.

Faraday Discuss. 2015;184:451-73. doi: 10.1039/c5fd90093j. Epub 2015 Dec 1. No abstract available.

PMID:
26620824
30.

Micheli Anterior Cruciate Ligament Reconstruction in Skeletally Immature Youths: A Retrospective Case Series With a Mean 3-Year Follow-up.

Willimon SC, Jones CR, Herzog MM, May KH, Leake MJ, Busch MT.

Am J Sports Med. 2015 Dec;43(12):2974-81. doi: 10.1177/0363546515608477. Epub 2015 Oct 23.

PMID:
26498959
31.

Single-molecule studies of the dynamics and interactions of bacterial OXPHOS complexes.

Lenn T, Leake MC.

Biochim Biophys Acta. 2016 Mar;1857(3):224-31. doi: 10.1016/j.bbabio.2015.10.008. Epub 2015 Oct 21.

33.

Probing DNA interactions with proteins using a single-molecule toolbox: inside the cell, in a test tube and in a computer.

Wollman AJ, Miller H, Zhou Z, Leake MC.

Biochem Soc Trans. 2015 Apr;43(2):139-45. doi: 10.1042/BST20140253. Review.

PMID:
26020443
34.

From Animaculum to single molecules: 300 years of the light microscope.

Wollman AJ, Nudd R, Hedlund EG, Leake MC.

Open Biol. 2015 Apr;5(4):150019. doi: 10.1098/rsob.150019. Review.

35.

Superresolution imaging of single DNA molecules using stochastic photoblinking of minor groove and intercalating dyes.

Miller H, Zhou Z, Wollman AJ, Leake MC.

Methods. 2015 Oct 15;88:81-8. doi: 10.1016/j.ymeth.2015.01.010. Epub 2015 Jan 27.

36.

Localisation and interactions of the Vipp1 protein in cyanobacteria.

Bryan SJ, Burroughs NJ, Shevela D, Yu J, Rupprecht E, Liu LN, Mastroianni G, Xue Q, Llorente-Garcia I, Leake MC, Eichacker LA, Schneider D, Nixon PJ, Mullineaux CW.

Mol Microbiol. 2014 Oct 13. doi: 10.1111/mmi.12826. [Epub ahead of print]

37.

Independent mobility of proteins and lipids in the plasma membrane of Escherichia coli.

Nenninger A, Mastroianni G, Robson A, Lenn T, Xue Q, Leake MC, Mullineaux CW.

Mol Microbiol. 2014 Jun;92(5):1142-53. doi: 10.1111/mmi.12619. Epub 2014 Apr 30.

38.

Analytical tools for single-molecule fluorescence imaging in cellulo.

Leake MC.

Phys Chem Chem Phys. 2014 Jul 7;16(25):12635-47. doi: 10.1039/c4cp00219a.

39.

Single-molecule in vivo imaging of bacterial respiratory complexes indicates delocalized oxidative phosphorylation.

Llorente-Garcia I, Lenn T, Erhardt H, Harriman OL, Liu LN, Robson A, Chiu SW, Matthews S, Willis NJ, Bray CD, Lee SH, Shin JY, Bustamante C, Liphardt J, Friedrich T, Mullineaux CW, Leake MC.

Biochim Biophys Acta. 2014 Jun;1837(6):811-24. doi: 10.1016/j.bbabio.2014.01.020. Epub 2014 Feb 7. Erratum in: Biochim Biophys Acta. 2017 Nov 22;:.

40.

Positioning of chemosensory proteins and FtsZ through the Rhodobacter sphaeroides cell cycle.

Chiu SW, Roberts MA, Leake MC, Armitage JP.

Mol Microbiol. 2013 Oct;90(2):322-37. doi: 10.1111/mmi.12366. Epub 2013 Sep 9.

41.

The physics of life: one molecule at a time.

Leake MC.

Philos Trans R Soc Lond B Biol Sci. 2012 Dec 24;368(1611):20120248. doi: 10.1098/rstb.2012.0248. Print 2013 Feb 5.

42.

Inferring diffusion in single live cells at the single-molecule level.

Robson A, Burrage K, Leake MC.

Philos Trans R Soc Lond B Biol Sci. 2012 Dec 24;368(1611):20120029. doi: 10.1098/rstb.2012.0029. Print 2013 Feb 5. Review.

43.

In vivo architecture and action of bacterial structural maintenance of chromosome proteins.

Badrinarayanan A, Reyes-Lamothe R, Uphoff S, Leake MC, Sherratt DJ.

Science. 2012 Oct 26;338(6106):528-31. doi: 10.1126/science.1227126.

44.

Association between acromial index and outcomes following arthroscopic repair of full-thickness rotator cuff tears.

Ames JB, Horan MP, Van der Meijden OA, Leake MJ, Millett PJ.

J Bone Joint Surg Am. 2012 Oct 17;94(20):1862-9. doi: 10.2106/JBJS.K.01500.

PMID:
23079878
45.
46.

Single molecule experimentation in biological physics: exploring the living component of soft condensed matter one molecule at a time.

Harriman OL, Leake MC.

J Phys Condens Matter. 2011 Dec 21;23(50):503101. doi: 10.1088/0953-8984/23/50/503101. Epub 2011 Nov 9.

PMID:
22067659
47.

Functioning nanomachines seen in real-time in living bacteria using single-molecule and super-resolution fluorescence imaging.

Chiu SW, Leake MC.

Int J Mol Sci. 2011;12(4):2518-42. doi: 10.3390/ijms12042518. Epub 2011 Apr 15. Review.

48.

Shining the spotlight on functional molecular complexes: The new science of single-molecule cell biology.

Leake MC.

Commun Integr Biol. 2010 Sep;3(5):415-8. doi: 10.4161/cib.3.5.12657.

49.

Signal-dependent turnover of the bacterial flagellar switch protein FliM.

Delalez NJ, Wadhams GH, Rosser G, Xue Q, Brown MT, Dobbie IM, Berry RM, Leake MC, Armitage JP.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11347-51. doi: 10.1073/pnas.1000284107. Epub 2010 May 24.

50.

Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.

Reyes-Lamothe R, Sherratt DJ, Leake MC.

Science. 2010 Apr 23;328(5977):498-501. doi: 10.1126/science.1185757.

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