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YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo.

Monroe TO, Hill MC, Morikawa Y, Leach JP, Heallen T, Cao S, Krijger PHL, de Laat W, Wehrens XHT, Rodney GG, Martin JF.

Dev Cell. 2019 Feb 12. pii: S1534-5807(19)30045-0. doi: 10.1016/j.devcel.2019.01.017. [Epub ahead of print]


Non-destructive detection of matrix stabilization correlates with enhanced mechanical properties of self-assembled articular cartilage.

Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA.

J Tissue Eng Regen Med. 2019 Feb 15. doi: 10.1002/term.2824. [Epub ahead of print]


Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.

Gay DM, Ridgway RA, Müeller M, Hodder MC, Hedley A, Clark W, Leach JD, Jackstadt R, Nixon C, Huels DJ, Campbell AD, Bird TG, Sansom OJ.

Nat Commun. 2019 Feb 13;10(1):723. doi: 10.1038/s41467-019-08586-3.


Direct, Real-Time Detection of Adenosine Triphosphate Release from Astrocytes in Three-Dimensional Culture Using an Integrated Electrochemical Aptamer-Based Sensor.

Santos-Cancel M, Simpson LW, Leach JB, White RJ.

ACS Chem Neurosci. 2019 Feb 20. doi: 10.1021/acschemneuro.9b00033. [Epub ahead of print]


Development of information sharing in language neocortex in childhood-onset drug-resistant epilepsy.

Arya R, Ervin B, Wilson JA, Byars AW, Rozhkov L, Buroker J, Horn PS, Scholle C, Fujiwara H, Greiner HM, Leach JL, Rose DF, Mangano FT, Glauser TA, Holland KD.

Epilepsia. 2019 Feb 11. doi: 10.1111/epi.14661. [Epub ahead of print]


Shared cis-regulatory architecture identified across defense response genes is associated with broad-spectrum quantitative resistance in rice.

Tonnessen BW, Bossa-Castro AM, Mauleon R, Alexandrov N, Leach JE.

Sci Rep. 2019 Feb 7;9(1):1536. doi: 10.1038/s41598-018-38195-x.


Neuropsychological outcomes after resection of cortical sites with visual naming associated electrocorticographic high-gamma modulation.

Arya R, Roth C, Leach JL, Middeler D, Wilson JA, Vannest J, Rozhkov L, Greiner HM, Buroker J, Scholle C, Fujiwara H, Horn PS, Rose DF, Crone NE, Mangano FT, Byars AW, Holland KD.

Epilepsy Res. 2019 Jan 29;151:17-23. doi: 10.1016/j.eplepsyres.2019.01.011. [Epub ahead of print]


The role of autologous stem cell transplantation in patients with nodal peripheral T-cell lymphomas in first complete remission: Report from COMPLETE, a prospective, multicenter cohort study.

Park SI, Horwitz SM, Foss FM, Pinter-Brown LC, Carson KR, Rosen ST, Pro B, Hsi ED, Federico M, Gisselbrecht C, Schwartz M, Bellm LA, Acosta M, Advani RH, Feldman T, Lechowicz MJ, Smith SM, Lansigan F, Tulpule A, Craig MD, Greer JP, Kahl BS, Leach JW, Morganstein N, Casulo C, Shustov AR.

Cancer. 2019 Jan 29. doi: 10.1002/cncr.31861. [Epub ahead of print]


Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI.

Zhu C, Leach JR, Tian B, Cao L, Wen Z, Wang Y, Liu X, Liu Q, Lu J, Saloner D, Hope MD.

J Magn Reson Imaging. 2019 Jan 29. doi: 10.1002/jmri.26676. [Epub ahead of print]


Comparative prevalence of Oxalobacter formigenes in three human populations.

PeBenito A, Nazzal L, Wang C, Li H, Jay M, Noya-Alarcon O, Contreras M, Lander O, Leach J, Dominguez-Bello MG, Blaser MJ.

Sci Rep. 2019 Jan 24;9(1):574. doi: 10.1038/s41598-018-36670-z.


Injectable mineralized microsphere-loaded composite hydrogels for bone repair in a sheep bone defect model.

Ingavle GC, Gionet-Gonzales M, Vorwald CE, Bohannon LK, Clark K, Galuppo LD, Leach JK.

Biomaterials. 2019 Mar;197:119-128. doi: 10.1016/j.biomaterials.2019.01.005. Epub 2019 Jan 10.


Treatment of epilepsy - towards precision.

Leach JP.

F1000Res. 2018 Dec 13;7. pii: F1000 Faculty Rev-1932. doi: 10.12688/f1000research.16448.1. eCollection 2018. Review.


Quarantining the OSCE: reflections on the Glasgow experience.

Noonan Z, Boyle JG, Pope L, Ditchfield C, Leach JP, McDowall S.

Clin Teach. 2018 Dec 27. doi: 10.1111/tct.12993. [Epub ahead of print] No abstract available.


Detection of glycosaminoglycan loss in articular cartilage by fluorescence lifetime imaging.

Zhou X, Haudenschild AK, Sherlock BE, Hu JC, Leach JK, Athanasiou KA, Marcu L.

J Biomed Opt. 2018 Dec;23(12):1-8. doi: 10.1117/1.JBO.23.12.126002.


The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.

Loerch S, Leach JR, Horner SW, Maji D, Jenkins JL, Pulvino M, Kielkopf CL.

J Biol Chem. 2018 Dec 19. pii: jbc.RA118.006764. doi: 10.1074/jbc.RA118.006764. [Epub ahead of print]


Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study.

Owonikoko TK, Dahlberg SE, Sica GL, Wagner LI, Wade JL 3rd, Srkalovic G, Lash BW, Leach JW, Leal TB, Aggarwal C, Ramalingam SS.

J Clin Oncol. 2019 Jan 20;37(3):222-229. doi: 10.1200/JCO.18.00264. Epub 2018 Dec 5.


Real-time local oxygen measurements for high resolution cellular imaging.

Boyman L, Williams GSB, Wescott AP, Leach JB, Kao JPY, Lederer WJ.

J Mol Cell Cardiol. 2019 Feb;127:97-104. doi: 10.1016/j.yjmcc.2018.11.021. Epub 2018 Dec 5.


Cell-secreted extracellular matrix, independent of cell source, promotes the osteogenic differentiation of human stromal vascular fraction.

Harvestine JN, Orbay H, Chen JY, Sahar DE, Leach JK.

J Mater Chem B. 2018 Jun 28;6(24):4104-4115. doi: 10.1039/C7TB02787G. Epub 2018 May 29.


Repairing the lungs one breath at a time: How dedicated or facultative are you?

Leach JP, Morrisey EE.

Genes Dev. 2018 Dec 1;32(23-24):1461-1471. doi: 10.1101/gad.319418.118. Review.


Gut microbiome transition across a lifestyle gradient in Himalaya.

Jha AR, Davenport ER, Gautam Y, Bhandari D, Tandukar S, Ng KM, Fragiadakis GK, Holmes S, Gautam GP, Leach J, Sherchand JB, Bustamante CD, Sonnenburg JL.

PLoS Biol. 2018 Nov 15;16(11):e2005396. doi: 10.1371/journal.pbio.2005396. eCollection 2018 Nov.


Restoring vasculogenic potential of endothelial cells from diabetic patients through spheroid formation.

Vorwald CE, Murphy KC, Leach JK.

Cell Mol Bioeng. 2018 Aug;11(4):267-278. doi: 10.1007/s12195-018-0531-1. Epub 2018 May 23.


Defining hydrogel properties to instruct lineage- and cell-specific mesenchymal differentiation.

Hung BP, Harvestine JN, Saiz AM, Gonzalez-Fernandez T, Sahar DE, Weiss ML, Leach JK.

Biomaterials. 2019 Jan;189:1-10. doi: 10.1016/j.biomaterials.2018.10.024. Epub 2018 Oct 22.


Direct Observation of Tunneling Nanotubes within Human Mesenchymal Stem Cell Spheroids.

Zhang J, Whitehead J, Liu Y, Yang Q, Leach JK, Liu GY.

J Phys Chem B. 2018 Nov 1;122(43):9920-9926. doi: 10.1021/acs.jpcb.8b07305. Epub 2018 Oct 23.


Altered brain microstructure in association with repetitive subconcussive head impacts and the potential protective effect of jugular vein compression: a longitudinal study of female soccer athletes.

Myer GD, Barber Foss K, Thomas S, Galloway R, DiCesare CA, Dudley J, Gadd B, Leach J, Smith D, Gubanich P, Meehan WP 3rd, Altaye M, Lavin P, Yuan W.

Br J Sports Med. 2018 Oct 15. pii: bjsports-2018-099571. doi: 10.1136/bjsports-2018-099571. [Epub ahead of print]


MR Venous Flow in Sigmoid Sinus Diverticulum.

Amans MR, Haraldsson H, Kao E, Kefayati S, Meisel K, Khangura R, Leach J, Jani ND, Faraji F, Ballweber M, Smith W, Saloner D.

AJNR Am J Neuroradiol. 2018 Nov;39(11):2108-2113. doi: 10.3174/ajnr.A5833. Epub 2018 Oct 11.


Comparative Rice Bran Metabolomics across Diverse Cultivars and Functional Rice Gene⁻Bran Metabolite Relationships.

Zarei I, Luna E, Leach JE, McClung A, Vilchez S, Koita O, Ryan EP.

Metabolites. 2018 Oct 9;8(4). pii: E63. doi: 10.3390/metabo8040063.


Hysteretic Photochromic Switching (HPS) in Doubly Doped GaN(Mg):Eu-A Summary of Recent Results.

Edwards PR, O'Donnell KP, Singh AK, Cameron D, Lorenz K, Yamaga M, Leach JH, Kappers MJ, Boćkowski M.

Materials (Basel). 2018 Sep 22;11(10). pii: E1800. doi: 10.3390/ma11101800. Review.


Pediatric Emergencies: Imaging of Pediatric Head Trauma.

O'Brien WT Sr, Caré MM, Leach JL.

Semin Ultrasound CT MR. 2018 Oct;39(5):495-514. doi: 10.1053/j.sult.2018.01.007. Epub 2018 Jan 31. Review.


'Give-up-itis' revisited: Neuropathology of extremis.

Leach J.

Med Hypotheses. 2018 Nov;120:14-21. doi: 10.1016/j.mehy.2018.08.009. Epub 2018 Aug 10.


Transformation of 2D group-III selenides to ultra-thin nitrides: enabling epitaxy on amorphous substrates.

Briggs N, Preciado MI, Lu Y, Wang K, Leach J, Li X, Xiao K, Subramanian S, Wang B, Haque A, Sinnott S, Robinson JA.

Nanotechnology. 2018 Nov 23;29(47):47LT02. doi: 10.1088/1361-6528/aae0bb. Epub 2018 Sep 12.


Managing addiction to prescribed opioids: the job of general practice?

Leach JM.

Br J Gen Pract. 2018 Sep;68(674):426-427. doi: 10.3399/bjgp18X698597. No abstract available.


In Planta Bacterial Transcriptomics Predict Plant Disease Outcomes.

Cohen SP, Jacobs JM, Leach JE.

Trends Plant Sci. 2018 Sep;23(9):751-753. doi: 10.1016/j.tplants.2018.06.008. Epub 2018 Jun 28.


Interactions of free-living amoebae with rice bacterial pathogens Xanthomonas oryzae pathovars oryzae and oryzicola.

Long JJ, Jahn CE, Sánchez-Hidalgo A, Wheat W, Jackson M, Gonzalez-Juarrero M, Leach JE.

PLoS One. 2018 Aug 24;13(8):e0202941. doi: 10.1371/journal.pone.0202941. eCollection 2018.


Impact of Low-Level Blast Exposure on Brain Function after a One-Day Tactile Training and the Ameliorating Effect of a Jugular Vein Compression Neck Collar Device.

Yuan W, Barber Foss KD, Dudley J, Thomas S, Galloway R, DiCesare C, Leach J, Scheifele P, Farina M, Valencia G, Smith D, Altaye M, Rhea CK, Talavage T, Myer GD.

J Neurotrauma. 2018 Oct 3. doi: 10.1089/neu.2018.5737. [Epub ahead of print]


Links between environment, diet, and the hunter-gatherer microbiome.

Fragiadakis GK, Smits SA, Sonnenburg ED, Van Treuren W, Reid G, Knight R, Manjurano A, Changalucha J, Dominguez-Bello MG, Leach J, Sonnenburg JL.

Gut Microbes. 2018 Aug 17:1-12. doi: 10.1080/19490976.2018.1494103. [Epub ahead of print]


Exogenous Lysyl Oxidase-Like 2 and Perfusion Culture Induce Collagen Crosslink Formation in Osteogenic Grafts.

Mitra D, Yasui OW, Harvestine JN, Link JM, Hu JC, Athanasiou KA, Leach JK.

Biotechnol J. 2018 Jul 27:e1700763. doi: 10.1002/biot.201700763. [Epub ahead of print]


Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties.

Haudenschild AK, Sherlock BE, Zhou X, Hu JC, Leach JK, Marcu L, Athanasiou KA.

Eur Cell Mater. 2018 Jul 27;36:30-43. doi: 10.22203/eCM.v036a03.


Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.

Gits HC, Anderson M, Stallard S, Pratt D, Zon B, Howell C, Kumar-Sinha C, Vats P, Kasaian K, Polan D, Matuszak M, Spratt DE, Leonard M, Qin T, Zhao L, Leach J, Chaney B, Escorza NY, Hendershot J, Jones B, Fuller C, Leary S, Bartels U, Bouffet E, Yock TI, Robertson P, Mody R, Venneti S, Chinnaiyan AM, Fouladi M, Gottardo NG, Koschmann C.

Acta Neuropathol Commun. 2018 Jul 26;6(1):67. doi: 10.1186/s40478-018-0570-9.


Materials-Directed Differentiation of Mesenchymal Stem Cells for Tissue Engineering and Regeneration.

Leach JK, Whitehead J.

ACS Biomater Sci Eng. 2018 Apr 9;4(4):1115-1127. doi: 10.1021/acsbiomaterials.6b00741. Epub 2017 Mar 14.


Does brain functional connectivity contribute to musculoskeletal injury? A preliminary prospective analysis of a neural biomarker of ACL injury risk.

Diekfuss JA, Grooms DR, Yuan W, Dudley J, Barber Foss KD, Thomas S, Ellis JD, Schneider DK, Leach J, Bonnette S, Myer GD.

J Sci Med Sport. 2019 Feb;22(2):169-174. doi: 10.1016/j.jsams.2018.07.004. Epub 2018 Jul 10.


Hypothesis: Multiple sclerosis is caused by three-hits, strictly in order, in genetically susceptible persons.

Kearns PKA, Casey HA, Leach JP.

Mult Scler Relat Disord. 2018 Aug;24:157-174. doi: 10.1016/j.msard.2018.06.014. Epub 2018 Jul 4.


Impact of radiotracer injection latency and seizure duration on subtraction ictal SPECT co-registered to MRI (SISCOM) performance in children.

Aungaroon G, Trout A, Radhakrishnan R, Horn PS, Arya R, Tenney JR, Arthur TM, Holland KD, Mangano FT, Leach JL, Rozhkov L, Greiner HM.

Clin Neurophysiol. 2018 Sep;129(9):1842-1848. doi: 10.1016/j.clinph.2018.06.010. Epub 2018 Jun 23.


Hypoxic Preconditioning of Mesenchymal Stem Cells with Subsequent Spheroid Formation Accelerates Repair of Segmental Bone Defects.

Ho SS, Hung BP, Heyrani N, Lee MA, Leach JK.

Stem Cells. 2018 Sep;36(9):1393-1403. doi: 10.1002/stem.2853. Epub 2018 Jul 3.


Cardiomyocyte Proliferation for Therapeutic Regeneration.

Leach JP, Martin JF.

Curr Cardiol Rep. 2018 Jun 14;20(8):63. doi: 10.1007/s11886-018-1011-x. Review.


Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf blight of rice.

Tran TT, Pérez-Quintero AL, Wonni I, Carpenter SCD, Yu Y, Wang L, Leach JE, Verdier V, Cunnac S, Bogdanove AJ, Koebnik R, Hutin M, Szurek B.

PLoS Pathog. 2018 Jun 4;14(6):e1007092. doi: 10.1371/journal.ppat.1007092. eCollection 2018 Jun.


American Gut: an Open Platform for Citizen Science Microbiome Research.

McDonald D, Hyde E, Debelius JW, Morton JT, Gonzalez A, Ackermann G, Aksenov AA, Behsaz B, Brennan C, Chen Y, DeRight Goldasich L, Dorrestein PC, Dunn RR, Fahimipour AK, Gaffney J, Gilbert JA, Gogul G, Green JL, Hugenholtz P, Humphrey G, Huttenhower C, Jackson MA, Janssen S, Jeste DV, Jiang L, Kelley ST, Knights D, Kosciolek T, Ladau J, Leach J, Marotz C, Meleshko D, Melnik AV, Metcalf JL, Mohimani H, Montassier E, Navas-Molina J, Nguyen TT, Peddada S, Pevzner P, Pollard KS, Rahnavard G, Robbins-Pianka A, Sangwan N, Shorenstein J, Smarr L, Song SJ, Spector T, Swafford AD, Thackray VG, Thompson LR, Tripathi A, Vázquez-Baeza Y, Vrbanac A, Wischmeyer P, Wolfe E, Zhu Q; American Gut Consortium , Knight R.

mSystems. 2018 May 15;3(3). pii: e00031-18. doi: 10.1128/mSystems.00031-18. eCollection 2018 May-Jun.


Day-to-Day Variability of Postural Sway and Its Association With Cognitive Function in Older Adults: A Pilot Study.

Leach JM, Mancini M, Kaye JA, Hayes TL, Horak FB.

Front Aging Neurosci. 2018 May 4;10:126. doi: 10.3389/fnagi.2018.00126. eCollection 2018.


Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M.

J Clin Oncol. 2018 Jul 1;36(19):1963-1972. doi: 10.1200/JCO.2017.75.9308. Epub 2018 May 10.


Attosecond-resolution Hong-Ou-Mandel interferometry.

Lyons A, Knee GC, Bolduc E, Roger T, Leach J, Gauger EM, Faccio D.

Sci Adv. 2018 May 4;4(5):eaap9416. doi: 10.1126/sciadv.aap9416. eCollection 2018 May.

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