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Items: 12

1.

Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition.

Schatoff EM, Goswami S, Zafra MP, Foronda M, Shusterman M, Leach BI, Katti A, Diaz BJ, Dow LE.

Cancer Discov. 2019 Oct;9(10):1358-1371. doi: 10.1158/2159-8290.CD-19-0289. Epub 2019 Jul 23.

PMID:
31337618
2.

NMR Measurements Reveal the Structural Basis of Transthyretin Destabilization by Pathogenic Mutations.

Leach BI, Zhang X, Kelly JW, Dyson HJ, Wright PE.

Biochemistry. 2018 Jul 31;57(30):4421-4430. doi: 10.1021/acs.biochem.8b00642. Epub 2018 Jul 18.

3.

Mechanisms of resistance to systemic therapy in metastatic castration-resistant prostate cancer.

Galletti G, Leach BI, Lam L, Tagawa ST.

Cancer Treat Rev. 2017 Jun;57:16-27. doi: 10.1016/j.ctrv.2017.04.008. Epub 2017 May 8. Review.

PMID:
28527407
4.

Wnt Signaling and Colorectal Cancer.

Schatoff EM, Leach BI, Dow LE.

Curr Colorectal Cancer Rep. 2017 Apr;13(2):101-110. doi: 10.1007/s11888-017-0354-9. Epub 2017 Feb 28.

5.

Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis.

Fedashchin A, Cernota WH, Gonzalez MC, Leach BI, Kwan N, Wesley RK, Weber JM.

FEMS Microbiol Lett. 2015 Nov;362(22). pii: fnv180. doi: 10.1093/femsle/fnv180. Epub 2015 Oct 13.

6.

Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.

Lokken AA, Achille NJ, Chang MJ, Lin JJ, Kuntimaddi A, Leach BI, Malik B, Nesbit JB, Zhang S, Bushweller JH, Zeleznik-Le NJ, Hemenway CS.

Leuk Res. 2014 Nov;38(11):1309-15. doi: 10.1016/j.leukres.2014.08.010. Epub 2014 Aug 24.

7.

Breast metastasis from nasopharyngeal carcinoma: A case report and review of the literature.

Leach BI, Sun B, Petrovic L, Liu SV.

Oncol Lett. 2013 Jun;5(6):1859-1861. Epub 2013 Apr 12.

8.

Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

Leach BI, Kuntimaddi A, Schmidt CR, Cierpicki T, Johnson SA, Bushweller JH.

Structure. 2013 Jan 8;21(1):176-183. doi: 10.1016/j.str.2012.11.011. Epub 2012 Dec 20.

9.

An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain.

Weber JM, Cernota WH, Gonzalez MC, Leach BI, Reeves AR, Wesley RK.

Appl Microbiol Biotechnol. 2012 Feb;93(4):1575-83. doi: 10.1007/s00253-011-3650-3. Epub 2011 Nov 4.

10.

Engineering of the methylmalonyl-CoA metabolite node of Saccharopolyspora erythraea for increased erythromycin production.

Reeves AR, Brikun IA, Cernota WH, Leach BI, Gonzalez MC, Weber JM.

Metab Eng. 2007 May;9(3):293-303. Epub 2007 Mar 24.

11.

CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding.

Adam PJ, Terrett JA, Steers G, Stockwin L, Loader JA, Fletcher GC, Lu LS, Leach BI, Mason S, Stamps AC, Boyd RS, Pezzella F, Gatter KC, Harris AL.

Br J Cancer. 2006 Aug 7;95(3):298-306.

12.

Effects of methylmalonyl-CoA mutase gene knockouts on erythromycin production in carbohydrate-based and oil-based fermentations of Saccharopolyspora erythraea.

Reeves AR, Brikun IA, Cernota WH, Leach BI, Gonzalez MC, Weber JM.

J Ind Microbiol Biotechnol. 2006 Jul;33(7):600-9. Epub 2006 Feb 21.

PMID:
16491356

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