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Items: 1 to 50 of 133

1.

The point prevalence of respiratory syncytial virus in hospital and community-based studies in children from Northern Australia: studies in a 'high-risk' population.

McCallum GB, Grimwood K, Oguoma VM, Leach AJ, Smith-Vaughan HC, Versteegh LA, Chang AB.

Rural Remote Health. 2019 Nov;19(4):5267. doi: 10.22605/RRH5267. Epub 2019 Nov 24.

2.

The ORVAC trial protocol: a phase IV, double-blind, randomised, placebo-controlled clinical trial of a third scheduled dose of Rotarix rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis.

Middleton BF, Jones MA, Waddington CS, Danchin M, McCallum C, Gallagher S, Leach AJ, Andrews R, Kirkwood C, Cunliffe N, Carapetis J, Marsh JA, Snelling T.

BMJ Open. 2019 Nov 14;9(11):e032549. doi: 10.1136/bmjopen-2019-032549.

3.

Povidone-iodine ear wash and oral cotrimoxazole for chronic suppurative otitis media in Australian aboriginal children: study protocol for factorial design randomised controlled trial.

Wigger C, Leach AJ, Beissbarth J, Oguoma V, Lennox R, Nelson S, Patel H, Chatfield M, Currie K, Coates H, Edwards K, Smith-Vaughan H, Hare K, Torzillo P, Tong S, Morris P.

BMC Pharmacol Toxicol. 2019 Jul 27;20(1):46. doi: 10.1186/s40360-019-0322-x.

4.
5.

Preventative and medical treatment of ear disease in remote or resource-constrained environments.

Brophy-Williams S, Jarosz K, Sommer J, Leach AJ, Morris PS.

J Laryngol Otol. 2019 Feb 1:1-14. doi: 10.1017/S0022215119000057. [Epub ahead of print]

PMID:
30706843
6.

Impact of the 23-valent pneumococcal polysaccharide vaccination in pregnancy against infant acute lower respiratory infections in the Northern Territory of Australia.

Binks MJ, Moberley SA, Balloch A, Leach AJ, Nelson S, Hare KM, Wilson C, Nelson J, Morris PS, Ware RS, Tang MLK, Torzillo PJ, Carapetis JR, Mulholland K, Andrews RM.

Pneumonia (Nathan). 2018 Dec 25;10:13. doi: 10.1186/s41479-018-0057-2. eCollection 2018.

7.

A comparison of flocked nylon swabs and non-flocked rayon swabs for detection of respiratory bacteria in nasopharyngeal carriage in Australian Indigenous children.

Wigger C, Morris PS, Stevens M, Smith-Vaughan H, Hare K, Beissbarth J, Leach AJ.

J Microbiol Methods. 2019 Feb;157:47-49. doi: 10.1016/j.mimet.2018.12.013. Epub 2018 Dec 19.

PMID:
30578888
8.

How low can we go? The implications of low bacterial load in respiratory microbiota studies.

Marsh RL, Nelson MT, Pope CE, Leach AJ, Hoffman LR, Chang AB, Smith-Vaughan HC.

Pneumonia (Nathan). 2018 Jul 5;10:7. doi: 10.1186/s41479-018-0051-8. eCollection 2018. Review.

9.

Bacteria and viruses in the nasopharynx immediately prior to onset of acute lower respiratory infections in Indigenous Australian children.

Smith-Vaughan HC, Binks MJ, Beissbarth J, Chang AB, McCallum GB, Mackay IM, Morris PS, Marsh RL, Torzillo PJ, Wurzel DF, Grimwood K, Nosworthy E, Gaydon JE, Leach AJ, MacHunter B, Chatfield MD, Sloots TP, Cheng AC.

Eur J Clin Microbiol Infect Dis. 2018 Sep;37(9):1785-1794. doi: 10.1007/s10096-018-3314-7. Epub 2018 Jun 29.

PMID:
29959609
10.

Recommendations for application of Haemophilus influenzae PCR diagnostics to respiratory specimens for children living in northern Australia: a retrospective re-analysis.

Beissbarth J, Binks MJ, Marsh RL, Chang AB, Leach AJ, Smith-Vaughan HC.

BMC Res Notes. 2018 May 21;11(1):323. doi: 10.1186/s13104-018-3429-z.

11.

Reduced nontypeable Haemophilus influenzae lower airway infection in children with chronic endobronchial suppuration vaccinated with the 10-valent pneumococcal H. influenzae protein D conjugate vaccine.

Hare KM, Smith-Vaughan HC, Leach AJ, Pizzutto SJ, McCallum GB, Chang AB.

Vaccine. 2018 Mar 20;36(13):1736-1742. doi: 10.1016/j.vaccine.2018.02.054. Epub 2018 Feb 23.

PMID:
29478754
12.

Effect of a price discount and consumer education strategy on food and beverage purchases in remote Indigenous Australia: a stepped-wedge randomised controlled trial.

Brimblecombe J, Ferguson M, Chatfield MD, Liberato SC, Gunther A, Ball K, Moodie M, Miles E, Magnus A, Mhurchu CN, Leach AJ, Bailie R; SHOP@RIC research collaborative.

Lancet Public Health. 2017 Feb;2(2):e82-e95. doi: 10.1016/S2468-2667(16)30043-3. Epub 2017 Jan 25.

13.

Ear, nose and throat surgery: All you need to know about the surgical approach to the management of middle-ear effusions in Australian Indigenous and non-Indigenous children.

Kong K, Lannigan FJ, Morris PS, Leach AJ, O'Leary SJ.

J Paediatr Child Health. 2017 Nov;53(11):1060-1064. doi: 10.1111/jpc.13757. Review.

PMID:
29148198
14.

Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination in the Western Australian Aboriginal population.

Collins DA, Hoskins A, Snelling T, Senasinghe K, Bowman J, Stemberger NA, Leach AJ, Lehmann D.

Pneumonia (Nathan). 2017 Sep 25;9:14. doi: 10.1186/s41479-017-0038-x. eCollection 2017.

15.

Streptococcus pneumoniae and chronic endobronchial infections in childhood.

Hare KM, Leach AJ, Smith-Vaughan HC, Chang AB, Grimwood K.

Pediatr Pulmonol. 2017 Dec;52(12):1532-1545. doi: 10.1002/ppul.23828. Epub 2017 Sep 18. Review.

PMID:
28922566
16.

Aboriginal and non-Aboriginal children in Western Australia carry different serotypes of pneumococci with different antimicrobial susceptibility profiles.

Dunne EM, Carville K, Riley TV, Bowman J, Leach AJ, Cripps AW, Murphy D, Jacoby P, Lehmann D; Kalgoorlie Otitis Media Research Project Team.

Pneumonia (Nathan). 2016 Sep 5;8:15. doi: 10.1186/s41479-016-0015-9. eCollection 2016.

17.

Geographic consistency in dominant, non-typeable Haemophilus influenzae genotypes colonising four distinct Australian paediatric groups: a cohort study.

Smith-Vaughan HC, Beissbarth J, Bowman J, Hare KM, Price EP, Pickering J, Lehmann D, Chang AB, Morris PS, Marsh RL, Leach AJ.

Pneumonia (Nathan). 2016 Aug 18;8:13. doi: 10.1186/s41479-016-0013-y. eCollection 2016.

18.

Limited impact of neonatal or early infant schedules of 7-valent pneumococcal conjugate vaccination on nasopharyngeal carriage of Streptococcus pneumoniae in Papua New Guinean children: A randomized controlled trial.

Aho C, Michael A, Yoannes M, Greenhill A, Jacoby P, Reeder J, Pomat W, Saleu G, Namuigi P, Phuanukoonnon S, Smith-Vaughan H, Leach AJ, Richmond P, Lehmann D; Neonatal Pneumococcal Conjugate Vaccine Trial Study Team.

Vaccine Rep. 2016 Dec;6:36-43. doi: 10.1016/j.vacrep.2016.08.002.

19.

Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsiveness.

Moberley S, Licciardi PV, Balloch A, Andrews R, Leach AJ, Kirkwood M, Binks P, Mulholland K, Carapetis J, Tang MLK, Skull S.

Vaccine. 2017 May 19;35(22):2908-2915. doi: 10.1016/j.vaccine.2017.04.040. Epub 2017 Apr 25.

20.

Culture of non-typeable Haemophilus influenzae from the nasopharynx: Not all media are equal.

Harris TM, Rumaseb A, Beissbarth J, Barzi F, Leach AJ, Smith-Vaughan HC.

J Microbiol Methods. 2017 Jun;137:3-5. doi: 10.1016/j.mimet.2017.03.012. Epub 2017 Mar 22.

PMID:
28342745
21.

Microbiology of otitis media in Indigenous Australian children: review.

Jervis-Bardy J, Carney AS, Duguid R, Leach AJ.

J Laryngol Otol. 2017 Jul;131(S2):S2-S11. doi: 10.1017/S0022215116009294. Epub 2017 Jan 16. Review.

PMID:
28088924
22.

Propensity of pneumococcal carriage serotypes to infect the lower airways of children with chronic endobronchial infections.

Hare KM, Smith-Vaughan HC, Chang AB, Pizzutto S, Petsky HL, McCallum GB, Leach AJ.

Vaccine. 2017 Feb 1;35(5):747-756. doi: 10.1016/j.vaccine.2016.12.059. Epub 2017 Jan 3.

PMID:
28062125
23.

General health, otitis media, nasopharyngeal carriage and middle ear microbiology in Northern Territory Aboriginal children vaccinated during consecutive periods of 10-valent or 13-valent pneumococcal conjugate vaccines.

Leach AJ, Wigger C, Beissbarth J, Woltring D, Andrews R, Chatfield MD, Smith-Vaughan H, Morris PS.

Int J Pediatr Otorhinolaryngol. 2016 Jul;86:224-32. doi: 10.1016/j.ijporl.2016.05.011. Epub 2016 May 11.

24.

A multi-centre open-label randomised non-inferiority trial comparing watchful waiting to antibiotic treatment for acute otitis media without perforation in low-risk urban Aboriginal and Torres Strait Islander children (the WATCH trial): study protocol for a randomised controlled trial.

Abbott P, Gunasekera H, Leach AJ, Askew D, Walsh R, Kong K, Girosi F, Bond C, Morris P, Lujic S, Hu W, Usherwood T, Tyson S, Spurling G, Douglas M, Schubert K, Chapman S, Siddiqui N, Murray R, Rabbitt K, Porykali B, Woodall C, Newman T, Reath J.

Trials. 2016 Mar 3;17(1):119. doi: 10.1186/s13063-016-1247-y.

25.

The short-term impact of each primary dose of pneumococcal conjugate vaccine on nasopharyngeal carriage: Systematic review and meta-analyses of randomised controlled trials.

Nicholls TR, Leach AJ, Morris PS.

Vaccine. 2016 Feb 3;34(6):703-13. doi: 10.1016/j.vaccine.2015.12.048. Epub 2015 Dec 29. Review.

26.

PneuMum: Impact from a randomised controlled trial of maternal 23-valent pneumococcal polysaccharide vaccination on middle ear disease amongst Indigenous infants, Northern Territory, Australia.

Binks MJ, Moberley SA, Balloch A, Leach AJ, Nelson S, Hare KM, Wilson C, Morris PS, Nelson J, Chatfield MD, Tang ML, Torzillo P, Carapetis JR, Mulholland EK, Andrews RM.

Vaccine. 2015 Nov 27;33(48):6579-87. doi: 10.1016/j.vaccine.2015.10.101. Epub 2015 Oct 31.

27.

Reduced middle ear infection with non-typeable Haemophilus influenzae, but not Streptococcus pneumoniae, after transition to 10-valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine.

Leach AJ, Wigger C, Hare K, Hampton V, Beissbarth J, Andrews R, Chatfield M, Smith-Vaughan H, Morris PS.

BMC Pediatr. 2015 Oct 19;15:162. doi: 10.1186/s12887-015-0483-8.

28.

Haemophilus influenzae isolates survive for up to 20 years at -70 °C in skim milk tryptone glucose glycerol broth (STGGB) if thawing is avoided during re-culture.

Hare KM, Smith-Vaughan HC, Beissbarth J, Leach AJ.

J Microbiol Methods. 2015 Dec;119:132-3. doi: 10.1016/j.mimet.2015.10.013. Epub 2015 Oct 22.

PMID:
26477641
29.

Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo.

Hare KM, Grimwood K, Chang AB, Chatfield MD, Valery PC, Leach AJ, Smith-Vaughan HC, Morris PS, Byrnes CA, Torzillo PJ, Cheng AC.

Eur J Clin Microbiol Infect Dis. 2015 Nov;34(11):2275-85. doi: 10.1007/s10096-015-2480-0. Epub 2015 Sep 12.

PMID:
26363637
30.

The microbiome of otitis media with effusion in Indigenous Australian children.

Jervis-Bardy J, Rogers GB, Morris PS, Smith-Vaughan HC, Nosworthy E, Leong LE, Smith RJ, Weyrich LS, De Haan J, Carney AS, Leach AJ, O'Leary S, Marsh RL.

Int J Pediatr Otorhinolaryngol. 2015 Sep;79(9):1548-55. doi: 10.1016/j.ijporl.2015.07.013. Epub 2015 Jul 17.

PMID:
26228497
31.

Pneumococcal conjugate vaccines PREVenar13 and SynflorIX in sequence or alone in high-risk Indigenous infants (PREV-IX_COMBO): protocol of a randomised controlled trial.

Leach AJ, Mulholland EK, Santosham M, Torzillo PJ, Brown NJ, McIntyre P, Smith-Vaughan H, Skull S, Balloch A, Andrews R, Carapetis J, McDonnell J, Krause V, Morris PS.

BMJ Open. 2015 Jan 16;5(1):e007247. doi: 10.1136/bmjopen-2014-007247.

32.

Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules.

Leach AJ, Wigger C, Andrews R, Chatfield M, Smith-Vaughan H, Morris PS.

BMC Pediatr. 2014 Aug 11;14:200. doi: 10.1186/1471-2431-14-200.

33.

Diversity of nontypeable Haemophilus influenzae strains colonizing Australian Aboriginal and non-Aboriginal children.

Pickering J, Smith-Vaughan H, Beissbarth J, Bowman JM, Wiertsema S, Riley TV, Leach AJ, Richmond P, Lehmann D, Kirkham LA.

J Clin Microbiol. 2014 May;52(5):1352-7. doi: 10.1128/JCM.03448-13. Epub 2014 Feb 5.

34.

Comparison of anti-pneumococcal antibodies in cord blood from Australian indigenous and Gambian neonates and the implications for otitis media.

Balloch A, Licciardi PV, Kemp AS, Leach AJ, Mulholland EK, Tang ML.

Pediatr Infect Dis J. 2014 Apr;33(4):e116-20. doi: 10.1097/INF.0000000000000202.

PMID:
24378950
35.

High nasopharyngeal carriage of non-vaccine serotypes in Western Australian aboriginal people following 10 years of pneumococcal conjugate vaccination.

Collins DA, Hoskins A, Bowman J, Jones J, Stemberger NA, Richmond PC, Leach AJ, Lehmann D.

PLoS One. 2013 Dec 3;8(12):e82280. doi: 10.1371/journal.pone.0082280. eCollection 2013.

36.

Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.

Satzke C, Turner P, Virolainen-Julkunen A, Adrian PV, Antonio M, Hare KM, Henao-Restrepo AM, Leach AJ, Klugman KP, Porter BD, Sá-Leão R, Scott JA, Nohynek H, O'Brien KL; WHO Pneumococcal Carriage Working Group.

Vaccine. 2013 Dec 17;32(1):165-79. doi: 10.1016/j.vaccine.2013.08.062. Review.

37.

Absence of an important vaccine and diagnostic target in carriage- and disease-related nontypeable Haemophilus influenzae.

Smith-Vaughan HC, Chang AB, Sarovich DS, Marsh RL, Grimwood K, Leach AJ, Morris PS, Price EP.

Clin Vaccine Immunol. 2014 Feb;21(2):250-2. doi: 10.1128/CVI.00632-13. Epub 2013 Nov 27.

38.

Surveillance of pneumococcal serotype 1 carriage during an outbreak of serotype 1 invasive pneumococcal disease in central Australia 2010-2012.

Lai JY, Cook H, Yip TW, Berthelsen J, Gourley S, Krause V, Smith H, Leach AJ, Smith-Vaughan H.

BMC Infect Dis. 2013 Sep 3;13:409. doi: 10.1186/1471-2334-13-409.

39.

Dominance of Haemophilus influenzae in ear discharge from Indigenous Australian children with acute otitis media with tympanic membrane perforation.

Smith-Vaughan HC, Binks MJ, Marsh RL, Kaestli M, Ward L, Hare KM, Pizzutto SJ, Thornton RB, Morris PS, Leach AJ.

BMC Ear Nose Throat Disord. 2013 Oct 8;13(1):12. doi: 10.1186/1472-6815-13-12.

40.

Longitudinal nasopharyngeal carriage and antibiotic resistance of respiratory bacteria in indigenous Australian and Alaska native children with bronchiectasis.

Hare KM, Singleton RJ, Grimwood K, Valery PC, Cheng AC, Morris PS, Leach AJ, Smith-Vaughan HC, Chatfield M, Redding G, Reasonover AL, McCallum GB, Chikoyak L, McDonald MI, Brown N, Torzillo PJ, Chang AB.

PLoS One. 2013 Aug 5;8(8):e70478. doi: 10.1371/journal.pone.0070478. Print 2013.

41.

Stores Healthy Options Project in Remote Indigenous Communities (SHOP@RIC): a protocol of a randomised trial promoting healthy food and beverage purchases through price discounts and in-store nutrition education.

Brimblecombe J, Ferguson M, Liberato SC, Ball K, Moodie ML, Magnus A, Miles E, Leach AJ, Chatfield MD, Ni Mhurchu C, O'Dea K, Bailie RS.

BMC Public Health. 2013 Aug 12;13:744. doi: 10.1186/1471-2458-13-744.

42.
43.

Quantitative PCR confirms culture as the gold standard for detection of lower airway infection by nontypeable Haemophilus influenzae in Australian Indigenous children with bronchiectasis.

Hare KM, Marsh RL, Binks MJ, Grimwood K, Pizzutto SJ, Leach AJ, Chang AB, Smith-Vaughan HC.

J Microbiol Methods. 2013 Mar;92(3):270-2. doi: 10.1016/j.mimet.2012.12.013. Epub 2012 Dec 22.

PMID:
23266579
44.

Association between early bacterial carriage and otitis media in Aboriginal and non-Aboriginal children in a semi-arid area of Western Australia: a cohort study.

Sun W, Jacoby P, Riley TV, Bowman J, Leach AJ, Coates H, Weeks S, Cripps A, Lehmann D; Kalgoorlie Otitis Media Research Project Team.

BMC Infect Dis. 2012 Dec 21;12:366. doi: 10.1186/1471-2334-12-366.

45.

Quantitative PCR of ear discharge from Indigenous Australian children with acute otitis media with perforation supports a role for Alloiococcus otitidis as a secondary pathogen.

Marsh RL, Binks MJ, Beissbarth J, Christensen P, Morris PS, Leach AJ, Smith-Vaughan HC.

BMC Ear Nose Throat Disord. 2012 Oct 3;12:11. doi: 10.1186/1472-6815-12-11.

46.

Impact of recent antibiotics on nasopharyngeal carriage and lower airway infection in Indigenous Australian children with non-cystic fibrosis bronchiectasis.

Hare KM, Leach AJ, Morris PS, Smith-Vaughan H, Torzillo P, Bauert P, Cheng AC, McDonald MI, Brown N, Chang AB, Grimwood K.

Int J Antimicrob Agents. 2012 Oct;40(4):365-9. doi: 10.1016/j.ijantimicag.2012.05.018. Epub 2012 Jul 20.

PMID:
22819151
47.

Potential use of serum based quantitative real-time PCR for the detection of pneumonia pathogens in a densely colonised population.

Lai JYR, Binks MJ, Kaestli M, Leach AJ, Smith-Vaughan HC.

Pneumonia (Nathan). 2012 Jul 24;1:7-10. doi: 10.15172/pneu.2012.1/209. eCollection 2012.

48.

Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian Indigenous children with bronchiectasis.

Hare KM, Binks MJ, Grimwood K, Chang AB, Leach AJ, Smith-Vaughan H.

J Clin Microbiol. 2012 Jul;50(7):2444-5. doi: 10.1128/JCM.00566-12. Epub 2012 May 2.

49.

Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

Binks MJ, Temple B, Kirkham LA, Wiertsema SP, Dunne EM, Richmond PC, Marsh RL, Leach AJ, Smith-Vaughan HC.

PLoS One. 2012;7(3):e34083. doi: 10.1371/journal.pone.0034083. Epub 2012 Mar 28.

50.

Contribution of serotype and genetic background to virulence of serotype 3 and serogroup 11 pneumococcal isolates.

McAllister LJ, Ogunniyi AD, Stroeher UH, Leach AJ, Paton JC.

Infect Immun. 2011 Dec;79(12):4839-49. doi: 10.1128/IAI.05663-11. Epub 2011 Sep 19.

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