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Items: 1 to 50 of 584

1.

Editorial: Hot Topics of Debate on Turner Syndrome: Growth, Puberty, Cardiovascular Risks, Fertility and Psychosocial Development.

Uçar A, Wong JSC, Darendeliler F, Holly JMP, Leroith D.

Front Endocrinol (Lausanne). 2019 Sep 19;10:644. doi: 10.3389/fendo.2019.00644. eCollection 2019. No abstract available.

2.

Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.

Jordan S, Tung N, Casanova-Acebes M, Chang C, Cantoni C, Zhang D, Wirtz TH, Naik S, Rose SA, Brocker CN, Gainullina A, Hornburg D, Horng S, Maier BB, Cravedi P, LeRoith D, Gonzalez FJ, Meissner F, Ochando J, Rahman A, Chipuk JE, Artyomov MN, Frenette PS, Piccio L, Berres ML, Gallagher EJ, Merad M.

Cell. 2019 Aug 22;178(5):1102-1114.e17. doi: 10.1016/j.cell.2019.07.050.

PMID:
31442403
3.

Bringing closure: towards achieving a better understanding of Israel.

Rosenstock J, Zimmet P, Skyler JS, Atkinson M, Schatz D, Buse JB, Kahn S, Hirsch IB, Leroith D, Alberti KG.

Lancet. 2019 Aug 17;394(10198):559. doi: 10.1016/S0140-6736(19)31760-X. Epub 2019 Jul 31. No abstract available.

PMID:
31376991
4.

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer.

Senapati P, Kato H, Lee M, Leung A, Thai C, Sanchez A, Gallagher EJ, LeRoith D, Seewaldt VL, Ann DK, Schones DE.

Epigenetics Chromatin. 2019 Jul 17;12(1):44. doi: 10.1186/s13072-019-0290-9.

5.

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis.

Ran L, Wang X, Mi A, Liu Y, Wu J, Wang H, Guo M, Sun J, Liu B, Li Y, Wang D, Jiang R, Wang N, Gao W, Zeng L, Huang L, Chen X, LeRoith D, Liang B, Li X, Wu Y.

iScience. 2019 Jun 28;16:106-121. doi: 10.1016/j.isci.2019.05.020. Epub 2019 May 16.

6.

Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.

LeRoith D, Biessels GJ, Braithwaite SS, Casanueva FF, Draznin B, Halter JB, Hirsch IB, McDonnell ME, Molitch ME, Murad MH, Sinclair AJ.

J Clin Endocrinol Metab. 2019 May 1;104(5):1520-1574. doi: 10.1210/jc.2019-00198.

PMID:
30903688
7.

The Association of Depressive Symptoms With Brain Volume Is Stronger Among Diabetic Elderly Carriers of the Haptoglobin 1-1 Genotype Compared to Non-carriers.

Livny A, Schnaider Beeri M, Heymann A, Schmeidler J, Moshier E, Tzukran R, Tsarfaty G, Leroith D, Preiss R, Soleimani L, Guerrero-Berroa E, Silverman JM, Bendlin B, Levy A, Ravona-Springer R.

Front Endocrinol (Lausanne). 2019 Feb 12;10:68. doi: 10.3389/fendo.2019.00068. eCollection 2019.

8.

A Message from the Editor-in-Chief.

LeRoith D.

Endocr Pract. 2019 Jan;25(1):5. doi: 10.4158/1934-2403-25.1.5. No abstract available.

PMID:
30742574
9.

Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease.

Robinson A, Lubitz I, Atrakchi-Baranes D, Licht-Murava A, Katsel P, Leroith D, Liraz-Zaltsman S, Haroutunian V, Beeri MS.

J Mol Neurosci. 2019 Apr;67(4):504-510. doi: 10.1007/s12031-019-1257-9. Epub 2019 Jan 11.

PMID:
30635783
10.

Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment.

Obr AE, Kumar S, Chang YJ, Bulatowicz JJ, Barnes BJ, Birge RB, Lazzarino DA, Gallagher E, LeRoith D, Wood TL.

Breast Cancer Res. 2018 Nov 20;20(1):138. doi: 10.1186/s13058-018-1063-2.

11.

Diabetes, Obesity, and Breast Cancer.

Kang C, LeRoith D, Gallagher EJ.

Endocrinology. 2018 Nov 1;159(11):3801-3812. doi: 10.1210/en.2018-00574. Review.

12.

Depressive Symptoms Are Associated with Cognitive Function in the Elderly with Type 2 Diabetes.

Guerrero-Berroa E, Ravona-Springer R, Schmeidler J, Heymann A, Soleimani L, Sano M, Leroith D, Preiss R, Zukran R, Silverman JM, Beeri MS.

J Alzheimers Dis. 2018;65(2):683-692. doi: 10.3233/JAD-170778.

13.

Age Modulates the Association of Caffeine Intake With Cognition and With Gray Matter in Elderly Diabetics.

West RK, Ravona-Springer R, Livny A, Heymann A, Shahar D, Leroith D, Preiss R, Zukran R, Silverman JM, Schnaider-Beeri M.

J Gerontol A Biol Sci Med Sci. 2019 Apr 23;74(5):683-688. doi: 10.1093/gerona/gly090.

14.

Big Topics for Diabetes Care in 2018: Clinical Guidelines, Costs of Diabetes, and Information Technology.

Riddle MC, Bakris G, Boulton AJM, Blonde L, D'Alessio D, Greene EL, de Groot M, Hood K, Hu FB, Kahn SE, Kaul S, LeRoith D, Moses RG, Rich SS, Rosenstock J, Tamborlane WV, Wylie-Rosett J, Reynolds L.

Diabetes Care. 2018 Jul;41(7):1327-1329. doi: 10.2337/dci18-0035. No abstract available.

PMID:
29934474
15.

World leaders describe the latest in IGF research.

Gallagher EJ, LeRoith D.

J Mol Endocrinol. 2018 Jul;61(1):E1-E3. doi: 10.1530/JME-18-0106. No abstract available.

16.

Insulin stimulates PKCζ -mediated phosphorylation of insulin receptor substrate-1 (IRS-1): A self-attenuated mechanism to negatively regulate the function of IRS proteins.

Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y.

J Biol Chem. 2018 May 11;293(19):7264. doi: 10.1074/jbc.W118.003466. No abstract available.

17.

Hyperinsulinemia Promotes Esophageal Cancer Development in a Surgically-Induced Duodeno-Esophageal Reflux Murine Model.

Arcidiacono D, Dedja A, Giacometti C, Fassan M, Nucci D, Francia S, Fabris F, Zaramella A, Gallagher EJ, Cassaro M, Rugge M, LeRoith D, Alberti A, Realdon S.

Int J Mol Sci. 2018 Apr 14;19(4). pii: E1198. doi: 10.3390/ijms19041198.

18.

A MESSAGE FROM THE EDITOR-IN-CHIEF.

LeRoith D.

Endocr Pract. 2018 Jan;24(1):5. doi: 10.4158/1934-2403-24.1.5. No abstract available.

PMID:
29368968
19.

New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.

Qiang X, Liotta AS, Shiloach J, Gutierrez JC, Wang H, Ochani M, Ochani K, Yang H, Rabin A, LeRoith D, Lesniak MA, Böhm M, Maaser C, Kannengiesser K, Donowitz M, Rabizadeh S, Czura CJ, Tracey KJ, Westlake M, Zarfeshani A, Mehdi SF, Danoff A, Ge X, Sanyal S, Schwartz GJ, Roth J.

NPJ Biofilms Microbiomes. 2017 Nov 13;3:31. doi: 10.1038/s41522-017-0039-9. eCollection 2017.

20.

Statin Use and Breast Cancer Prognosis in Black and White Women.

Leiter A, Bickell NA, LeRoith D, Nayak A, Feldman SM, Friedman NB, Estabrook A, King TA, Fei K, Franco R, Gallagher EJ.

Horm Cancer. 2018 Feb;9(1):55-61. doi: 10.1007/s12672-017-0312-7. Epub 2017 Oct 19.

21.

Hexarelin, a Growth Hormone Secretagogue, Improves Lipid Metabolic Aberrations in Nonobese Insulin-Resistant Male MKR Mice.

Mosa R, Huang L, Wu Y, Fung C, Mallawakankanamalage O, LeRoith D, Chen C.

Endocrinology. 2017 Oct 1;158(10):3174-3187. doi: 10.1210/en.2017-00168.

22.

Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon.

Jao J, Powis KM, Kirmse B, Yu C, Epie F, Nshom E, Abrams EJ, Sperling RS, Leroith D, Geffner ME, Kurland IJ, Côté HCF.

AIDS. 2017 Nov 28;31(18):2475-2481. doi: 10.1097/QAD.0000000000001647.

23.

Long-term treatment with the ghrelin receptor antagonist [d-Lys3]-GHRP-6 does not improve glucose homeostasis in nonobese diabetic MKR mice.

Mosa R, Huang L, Li H, Grist M, LeRoith D, Chen C.

Am J Physiol Regul Integr Comp Physiol. 2018 Jan 1;314(1):R71-R83. doi: 10.1152/ajpregu.00157.2017. Epub 2017 Sep 13.

24.

OP449 inhibits breast cancer growth without adverse metabolic effects.

Shlomai G, Zelenko Z, Antoniou IM, Stasinopoulos M, Tobin-Hess A, Vitek MP, LeRoith D, Gallagher EJ.

Endocr Relat Cancer. 2017 Oct;24(10):519-529. doi: 10.1530/ERC-17-0077.

25.

THE INTERPLAY BETWEEN ENDOCRINOLOGY AND ONCOLOGY: THE NEW ROLE OF THE ENDOCRINOLOGIST.

Gallagher EJ, LeRoith D.

Endocr Pract. 2017 Oct;23(10):1167-1168. doi: 10.4158/EP171997.ED. Epub 2017 Aug 17. No abstract available.

PMID:
28816528
26.

Activating Transcription Factor-5 Knockdown Reduces Aggressiveness of Mammary Tumor Cells and Attenuates Mammary Tumor Growth.

Ben-Shmuel S, Rashed R, Rostoker R, Isakov E, Shen-Orr Z, LeRoith D.

Front Endocrinol (Lausanne). 2017 Jul 21;8:173. doi: 10.3389/fendo.2017.00173. eCollection 2017.

27.

Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia.

Gallagher EJ, Zelenko Z, Neel BA, Antoniou IM, Rajan L, Kase N, LeRoith D.

Oncogene. 2017 Nov 16;36(46):6462-6471. doi: 10.1038/onc.2017.247. Epub 2017 Jul 31.

28.

Hemoglobin A1c Variability Predicts Symptoms of Depression in Elderly Individuals With Type 2 Diabetes.

Ravona-Springer R, Heymann A, Schmeidler J, Moshier E, Guerrero-Berroa E, Soleimani L, Sano M, Leroith D, Preiss R, Tzukran R, Silverman JM, Beeri MS.

Diabetes Care. 2017 Sep;40(9):1187-1193. doi: 10.2337/dc16-2754. Epub 2017 Jun 20.

29.

Erratum to: Non-metabolisable insulin glargine does not promote breast cancer growth in a mouse model of type 2 diabetes.

Gallagher EJ, Zelenko Z, Tobin-Hess A, Werner U, Tennagels N, LeRoith D.

Diabetologia. 2017 Apr;60(4):758-759. doi: 10.1007/s00125-017-4225-3. No abstract available.

PMID:
28229179
30.

A Message from the Editor-in-Chief.

LeRoith D.

Endocr Pract. 2017 Jan;23(1):4. doi: 10.4158/1934-2403-23.1.4. No abstract available.

PMID:
28118042
31.

Diabetes Care: "Taking It to the Limit One More Time".

Cefalu WT, Boulton AJ, Tamborlane WV, Moses RG, LeRoith D, Greene EL, Hu FB, Bakris G, Wylie-Rosett J, Rosenstock J, Kahn SE, Weinger K, Blonde L, de Groot M, Rich S, D'Alessio D, Reynolds L, Riddle MC.

Diabetes Care. 2017 Jan;40(1):3-6. doi: 10.2337/dc16-2326. No abstract available.

32.

Type 2 Diabetes Mellitus and Cancer: The Role of Pharmacotherapy.

Shlomai G, Neel B, LeRoith D, Gallagher EJ.

J Clin Oncol. 2016 Dec 10;34(35):4261-4269. Epub 2016 Nov 7. Review.

33.

Diabetes Care: "Lagniappe" and "Seeing Is Believing"!

Cefalu WT, Boulton AJ, Tamborlane WV, Moses RG, LeRoith D, Greene EL, Hu FB, Bakris G, Wylie-Rosett J, Rosenstock J, Weinger K, Blonde L, de Groot M, Rich SS, D'Alessio D, Riddle MC, Reynolds L.

Diabetes Care. 2016 Jul;39(7):1069-71. doi: 10.2337/dc16-0891. Epub 2016 Jun 9. No abstract available.

34.

Building Momentum: Taking on the Real “Issues” of Diabetes Care!

Cefalu WT, Boulton AJ, Tamborlane WV, Moses RG, LeRoith D, Greene EL, Hu FB, Bakris G, Wylie-Rosett J, Rosenstock J, Weinger K, Blonde L, de Groot M, Riddle MC, Hill Golden S, Rich SS, D'Alessio D, Reynolds L.

Diabetes Care. 2016 Jan;39(1):10-12. doi: 10.2337/dc15-2315. No abstract available.

35.

Silencing vimentin expression decreases pulmonary metastases in a pre-diabetic mouse model of mammary tumor progression.

Zelenko Z, Gallagher EJ, Tobin-Hess A, Belardi V, Rostoker R, Blank J, Dina Y, LeRoith D.

Oncogene. 2017 Mar;36(10):1394-1403. doi: 10.1038/onc.2016.305. Epub 2016 Aug 29.

36.

Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways.

Werner H, Sarfstein R, LeRoith D, Bruchim I.

Front Oncol. 2016 Jun 23;6:159. doi: 10.3389/fonc.2016.00159. eCollection 2016. Review.

37.

Anti-inflammatory Agents in the Treatment of Diabetes and Its Vascular Complications.

Pollack RM, Donath MY, LeRoith D, Leibowitz G.

Diabetes Care. 2016 Aug;39 Suppl 2:S244-52. doi: 10.2337/dcS15-3015. Review.

PMID:
27440839
38.

EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice.

Zelenko Z, Gallagher EJ, Antoniou IM, Sachdev D, Nayak A, Yee D, LeRoith D.

Endocr Relat Cancer. 2016 Sep;23(9):747-58. doi: 10.1530/ERC-16-0142. Epub 2016 Jul 19.

39.

Non-metabolisable insulin glargine does not promote breast cancer growth in a mouse model of type 2 diabetes.

Gallagher EJ, Zelenko Z, Tobin-Hess A, Werner U, Tennagels N, LeRoith D.

Diabetologia. 2016 Sep;59(9):2018-25. doi: 10.1007/s00125-016-4000-x. Epub 2016 May 30. Erratum in: Diabetologia. 2017 Apr;60(4):758-759.

40.

Getting to the "Heart" of the Matter on Diabetic Cardiovascular Disease: "Thanks for the Memory".

Cefalu WT, Rosenstock J, LeRoith D, Blonde L, Riddle MC.

Diabetes Care. 2016 May;39(5):664-7. doi: 10.2337/dc16-0405. No abstract available.

41.

Polyol accumulation in muscle and liver in a mouse model of type 2 diabetes.

Gallagher EJ, LeRoith D, Stasinopoulos M, Zelenko Z, Shiloach J.

J Diabetes Complications. 2016 Aug;30(6):999-1007. doi: 10.1016/j.jdiacomp.2016.04.019. Epub 2016 Apr 27.

42.

CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy.

Rostoker R, Ben-Shmuel S, Rashed R, Shen Orr Z, LeRoith D.

Breast Cancer Res. 2016 May 14;18(1):51. doi: 10.1186/s13058-016-0711-7.

43.

Waist circumference is correlated with poorer cognition in elderly type 2 diabetes women.

West RK, Ravona-Springer R, Heymann A, Schmeidler J, Leroith D, Koifman K, D'Arcy RC, Song X, Guerrero-Berroa E, Preiss R, Hoffman H, Sano M, Silverman JM, Schnaider-Beeri M.

Alzheimers Dement. 2016 Aug;12(8):925-9. doi: 10.1016/j.jalz.2016.03.017. Epub 2016 May 2.

44.

Synthesis: Deriving a Core Set of Recommendations to Optimize Diabetes Care on a Global Scale.

Mechanick JI, Leroith D.

Ann Glob Health. 2015 Nov-Dec;81(6):874-83. doi: 10.1016/j.aogh.2016.02.008. Review.

45.

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON THE ASSOCIATION OF SGLT-2 INHIBITORS AND DIABETIC KETOACIDOSIS.

Handelsman Y, Henry RR, Bloomgarden ZT, Dagogo-Jack S, DeFronzo RA, Einhorn D, Ferrannini E, Fonseca VA, Garber AJ, Grunberger G, LeRoith D, Umpierrez GE, Weir MR.

Endocr Pract. 2016 Jun;22(6):753-62. doi: 10.4158/EP161292.PS. Epub 2016 Jun 1.

PMID:
27082665
46.

Metabolic syndrome and pre-diabetes contribute to racial disparities in breast cancer outcomes: hypothesis and proposed pathways.

Gallagher EJ, LeRoith D, Franco R, Antoniou IM, Nayak A, Livaudais-Toman J, Bickell NA.

Diabetes Metab Res Rev. 2016 Oct;32(7):745-753. doi: 10.1002/dmrr.2795. Epub 2016 Apr 21.

47.

Prediabetes and diabetes among HIV-infected adults in Cameroon.

Rhee JY, Bahtila TD, Palmer D, Tih PM, Aberg JA, LeRoith D, Jao J.

Diabetes Metab Res Rev. 2016 Sep;32(6):544-9. doi: 10.1002/dmrr.2792. Epub 2016 Apr 6.

48.

High dietary advanced glycation end products are associated with poorer spatial learning and accelerated Aβ deposition in an Alzheimer mouse model.

Lubitz I, Ricny J, Atrakchi-Baranes D, Shemesh C, Kravitz E, Liraz-Zaltsman S, Maksin-Matveev A, Cooper I, Leibowitz A, Uribarri J, Schmeidler J, Cai W, Kristofikova Z, Ripova D, LeRoith D, Schnaider-Beeri M.

Aging Cell. 2016 Apr;15(2):309-16. doi: 10.1111/acel.12436. Epub 2016 Jan 19.

49.

Insulin's Role in Diabetes Management: After 90 Years, Still Considered the Essential "Black Dress".

Cefalu WT, Rosenstock J, LeRoith D, Riddle MC.

Diabetes Care. 2015 Dec;38(12):2200-3. doi: 10.2337/dci15-0023. No abstract available.

50.

Reproductive Endocrinology.

LeRoith D.

Endocrinol Metab Clin North Am. 2015 Dec;44(4):xiii-xv. doi: 10.1016/j.ecl.2015.09.015. No abstract available.

PMID:
26568499

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