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Local Consolidation Therapy (LCT) After First Line Tyrosine Kinase Inhibitor (TKI) for Patients With EGFR Mutant Metastatic Non-small-cell Lung Cancer (NSCLC).

Elamin YY, Gomez DR, Antonoff MB, Robichaux JP, Tran H, Shorter MK, Bohac JM, Negrao MV, Le X, Rinsurogkawong W, Lewis J, Lacerda L, Roarty EB, Swisher SG, Roth JA, Zhang J, Papadimitrakopoulou V, Heymach JV.

Clin Lung Cancer. 2018 Sep 24. pii: S1525-7304(18)30260-2. doi: 10.1016/j.cllc.2018.09.015. [Epub ahead of print]


An expression signature model to predict lung adenocarcinoma-specific survival.

Shi X, Tan H, Le X, Xian H, Li X, Huang K, Luo VY, Liu Y, Wu Z, Mo H, Chen AM, Liang Y, Zhang J.

Cancer Manag Res. 2018 Sep 24;10:3717-3732. doi: 10.2147/CMAR.S159563. eCollection 2018.


Customers' Knowledge, Attitude, and Practices towards Food Hygiene and Safety Standards of Handlers in Food Facilities in Hanoi, Vietnam.

Nguyen ATL, Tran BX, Le HT, Le XTT, Do KN, Do HT, Vu GT, Nguyen LH, Latkin CA, Ho CSH, Ho RCM.

Int J Environ Res Public Health. 2018 Sep 25;15(10). pii: E2101. doi: 10.3390/ijerph15102101.


Landscape of EGFR -dependent and -independent resistance mechanisms to osimertinib and continuation therapy post-progression in EGFR-mutant NSCLC.

Le X, Puri S, Negrao MV, Nilsson M, Robichaux JP, Boyle TA, Hicks JK, Lovinger K, Roarty EB, Rinsurongkawong W, Tang M, Sun H, Elamin YY, Lacerda L, Lewis J, Lee JJ, Roth JA, Swisher SG, Zhang J, William WN, Glisson BS, Papadimitrakopoulou VA, Gray JE, Heymach JV.

Clin Cancer Res. 2018 Sep 18. pii: clincanres.1542.2018. doi: 10.1158/1078-0432.CCR-18-1542. [Epub ahead of print]


Low Temperature Oxidation Kinetics of Biodiesel Molecules: Rate Rules for Concerted HO2 Elimination from Alkyl Ester Peroxy Radicals.

Le XT, Mai TV, Lin KC, Huynh LK.

J Phys Chem A. 2018 Oct 25;122(42):8259-8273. doi: 10.1021/acs.jpca.8b05070. Epub 2018 Oct 11.


A consensus on the role of osimertinib in non-small cell lung cancer from the AME Lung Cancer Collaborative Group.

Jiang T, Su C, Ren S, Cappuzzo F, Rocco G, Palmer JD, van Zandwijk N, Blackhall F, Le X, Pennell NA, Zhou C; written on behalf of the AME Lung Cancer Collaborative Group.

J Thorac Dis. 2018 Jul;10(7):3909-3921. doi: 10.21037/jtd.2018.07.61. Review.


Robot-Assisted Versus Fluoroscopy-Assisted Cortical Bone Trajectory Screw Instrumentation in Lumbar Spinal Surgery: A Matched-Cohort Comparison.

Le X, Tian W, Shi Z, Han X, Liu Y, Liu B, He D, Yuan Q, Sun Y, Xu Y.

World Neurosurg. 2018 Aug 30. pii: S1878-8750(18)31940-5. doi: 10.1016/j.wneu.2018.08.157. [Epub ahead of print]


Adsorption of catechin onto cellulose and its mechanism study: Kinetic models, characterization and molecular simulation.

Liu Y, Ying D, Sanguansri L, Cai Y, Le X.

Food Res Int. 2018 Oct;112:225-232. doi: 10.1016/j.foodres.2018.06.044. Epub 2018 Jun 21.


Reduction of Background Generated from Template-Template Hybridizations in the Exponential Amplification Reaction.

Reid MS, Paliwoda RE, Zhang H, Le XC.

Anal Chem. 2018 Sep 18;90(18):11033-11039. doi: 10.1021/acs.analchem.8b02788. Epub 2018 Aug 27.


Antibody-Bridged Beacon for Homogeneous Detection of Small Molecules.

Yan X, Le XC, Zhang H.

Anal Chem. 2018 Aug 21;90(16):9667-9672. doi: 10.1021/acs.analchem.8b02510. Epub 2018 Aug 8.


Molecular analysis of Newcastle disease virus isolates reveals a novel XIId subgenotype in Vietnam.

Le XTK, Doan HTT, Le TH.

Arch Virol. 2018 Nov;163(11):3125-3130. doi: 10.1007/s00705-018-3961-0. Epub 2018 Jul 27.


Synthesis, characterization, DNA/HSA interactions and in vitro cytotoxic activities of two novel water-soluble copper(II) complexes with 1,3,5-triazine derivative ligand and amino acids.

Zhang CL, Liu YX, Zhang XM, Chen S, Shen F, Xiong YH, Liu W, Mao ZW, Le XY.

Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:414-425. doi: 10.1016/j.msec.2018.05.065. Epub 2018 May 22.


Optimal regimen of cisplatin in squamous cell carcinoma of head and neck yet to be determined.

Le X, Hanna EY.

Ann Transl Med. 2018 Jun;6(11):229. doi: 10.21037/atm.2018.05.10. No abstract available.


N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway.

Cheng Y, Yang C, Luo D, Li X, Le XC, Rong J.

Cell Physiol Biochem. 2018;47(6):2544-2557. doi: 10.1159/000491651. Epub 2018 Jul 11.


Computer-assisted, minimally invasive transforaminal lumbar interbody fusion: One surgeon's learning curve A STROBE-compliant article.

Xu YF, Le XF, Tian W, Liu B, Li Q, Zhang GL, Liu YJ, Yuan Q, He D, Mao JP, Xiao B, Lang Z, Han XG, Jin PH.

Medicine (Baltimore). 2018 Jul;97(27):e11423. doi: 10.1097/MD.0000000000011423.


[Application of chest CT scan in gestational trophoblastic neoplasia with lung metastasis].

Cheng Y, Ma FH, Wang XR, Le XN, Zhang GF, Lu X.

Zhonghua Fu Chan Ke Za Zhi. 2018 Jun 25;53(6):384-389. doi: 10.3760/cma.j.issn.0529-567x.2018.06.005. Chinese.


Maternal exposure to specific perfluoroalkyl substances is associated with increasing blood glucose in pregnant women.

Uppal JS, Zheng Q, Le XC.

J Environ Sci (China). 2018 Jul;69:1-2. doi: 10.1016/j.jes.2018.06.008. No abstract available.


Binding-Induced Molecular Amplifier as a Universal Detection Platform for Biomolecules and Biomolecular Interaction.

Li F, Lin Y, Lau A, Tang Y, Chen J, Le XC.

Anal Chem. 2018 Jul 17;90(14):8651-8657. doi: 10.1021/acs.analchem.8b01985. Epub 2018 Jun 21.


Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2'-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs: Special exploration of their possible anticancer mechanism.

Qi YY, Gan Q, Liu YX, Xiong YH, Mao ZW, Le XY.

Eur J Med Chem. 2018 Jun 25;154:220-232. doi: 10.1016/j.ejmech.2018.05.023. Epub 2018 May 21.


Ovalbumin as a carrier to significantly enhance the aqueous solubility and photostability of curcumin: Interaction and binding mechanism study.

Liu Y, Cai Y, Ying D, Fu Y, Xiong Y, Le X.

Int J Biol Macromol. 2018 Sep;116:893-900. doi: 10.1016/j.ijbiomac.2018.05.089. Epub 2018 May 16.


Multidrug Resistance Protein 1 (MRP1/ABCC1)-Mediated Cellular Protection and Transport of Methylated Arsenic Metabolites Differs between Human Cell Lines.

Banerjee M, Kaur G, Whitlock BD, Carew MW, Le XC, Leslie EM.

Drug Metab Dispos. 2018 Aug;46(8):1096-1105. doi: 10.1124/dmd.117.079640. Epub 2018 May 11.


Exponential Isothermal Amplification of Nucleic Acids and Assays for Proteins, Cells, Small Molecules, and Enzyme Activities: An EXPAR Example.

Reid MS, Le XC, Zhang H.

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):11856-11866. doi: 10.1002/anie.201712217. Epub 2018 Aug 15. Review.


Shape Memory Hydrogels with Simultaneously Switchable Fluorescence Behavior.

Jian YK, Le XX, Zhang YC, Lu W, Wang L, Zheng J, Zhang JW, Huang YJ, Chen T.

Macromol Rapid Commun. 2018 Jun;39(12):e1800130. doi: 10.1002/marc.201800130. Epub 2018 Apr 26.


Arsenic speciation in hair and nails of acute promyelocytic leukemia (APL) patients undergoing arsenic trioxide treatment.

Chen B, Cao F, Lu X, Shen S, Zhou J, Le XC.

Talanta. 2018 Jul 1;184:446-451. doi: 10.1016/j.talanta.2018.03.021. Epub 2018 Mar 14.


Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis.

Zhao L, Huang S, Mei S, Yang Z, Xu L, Zhou N, Yang Q, Shen Q, Wang W, Le X, Lau WB, Lau B, Wang X, Yi T, Zhao X, Wei Y, Warner M, Gustafsson JÅ, Zhou S.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3673-E3681. doi: 10.1073/pnas.1803291115. Epub 2018 Mar 28.


Parameter-specific analgesic effects of electroacupuncture mediated by degree of regulation TRPV1 and P2X3 in inflammatory pain in rats.

Fang JQ, Du JY, Fang JF, Xiao T, Le XQ, Pan NF, Yu J, Liu BY.

Life Sci. 2018 May 1;200:69-80. doi: 10.1016/j.lfs.2018.03.028. Epub 2018 Mar 14.


The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts.

Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, Zhou X, Wang J, Shen Q, Wang C, Le X, Feng M, Zhou N, Lau WB, Lau B, Yao S, Yi T, Wang X, Zhao X, Wei Y, Zhou S.

Genome Biol. 2018 Mar 16;19(1):35. doi: 10.1186/s13059-018-1412-6.


Evaluating Food Safety Knowledge and Practices of Food Processors and Sellers Working in Food Facilities in Hanoi, Vietnam.

Tran BX, DO HT, Nguyen LT, Boggiano V, LE HT, LE XTT, Trinh NB, DO KN, Nguyen CT, Nguyen TT, Dang AK, Mai HT, Nguyen LH, Than S, Latkin CA.

J Food Prot. 2018 Apr;81(4):646-652. doi: 10.4315/0362-028X.JFP-17-161.


A Novel Anisotropic Hydrogel with Integrated Self-Deformation and Controllable Shape Memory Effect.

Le XX, Zhang YC, Lu W, Wang L, Zheng J, Ali I, Zhang JW, Huang YJ, Serpe MJ, Yang XT, Fan XD, Chen T.

Macromol Rapid Commun. 2018 May;39(9):e1800019. doi: 10.1002/marc.201800019. Epub 2018 Mar 13.


Metabolomic analysis of two rice (Oryza sativa) varieties exposed to 2, 2', 4, 4'-tetrabromodiphenyl ether.

Chen J, Li K, Le XC, Zhu L.

Environ Pollut. 2018 Jun;237:308-317. doi: 10.1016/j.envpol.2018.02.027. Epub 2018 Mar 15.


Transfer of arsenic from poultry feed to poultry litter: A mass balance study.

Gupta SK, Le XC, Kachanosky G, Zuidhof MJ, Siddique T.

Sci Total Environ. 2018 Jul 15;630:302-307. doi: 10.1016/j.scitotenv.2018.02.123. Epub 2018 Feb 23.


Characterization of Mechanisms of Glutathione Conjugation with Halobenzoquinones in Solution and HepG2 Cells.

Wang W, Qian Y, Li J, Aljuhani N, Siraki AG, Le XC, Li XF.

Environ Sci Technol. 2018 Mar 6;52(5):2898-2908. doi: 10.1021/acs.est.7b05945. Epub 2018 Feb 23.


Factors Associated with Cigarette Smoking and Motivation to Quit among Street Food Sellers in Vietnam.

Le XTT, To LT, Le HT, Hoang HD, Do KN, Nguyen CT, Tran BX, Do HP, Nguyen LT, Latkin CA, Zhang MWB, Ho RCM.

Int J Environ Res Public Health. 2018 Jan 29;15(2). pii: E223. doi: 10.3390/ijerph15020223.


Feasibility of e-Health Interventions on Smoking Cessation among Vietnamese Active Internet Users.

Tran BX, Le XTT, Nguyen PN, Le QNH, Mai HT, Nguyen HLT, Le HT, Tran TT, Latkin CA, Zhang MWB, Ho RCM.

Int J Environ Res Public Health. 2018 Jan 20;15(1). pii: E165. doi: 10.3390/ijerph15010165.


Squid ink polysaccharide prevents chemotherapy induced injury in the testes of reproducing mice.

Luo P, Liu HZ, Le XY, Du H, Kang XH.

Pak J Pharm Sci. 2018 Jan;31(1):25-29.


Actuating and memorizing bilayer hydrogels for a self-deformed shape memory function.

Wang L, Jian Y, Le X, Lu W, Ma C, Zhang J, Huang Y, Huang CF, Chen T.

Chem Commun (Camb). 2018 Jan 31;54(10):1229-1232. doi: 10.1039/c7cc09456f.


Metabolism of a Phenylarsenical in Human Hepatic Cells and Identification of a New Arsenic Metabolite.

Liu Q, Leslie EM, Moe B, Zhang H, Douglas DN, Kneteman NM, Le XC.

Environ Sci Technol. 2018 Feb 6;52(3):1386-1392. doi: 10.1021/acs.est.7b05081. Epub 2018 Jan 17.


Moving more potent and less toxic options to the frontline in the management of advanced lung cancer.

Le X, Rangachari D, Costa DB.

J Thorac Dis. 2017 Sep;9(9):2812-2818. doi: 10.21037/jtd.2017.08.79. No abstract available.


Arsenic biotransformation and an arsenite S-adenosylmethionine methyltransferase in plankton.

Uppal JS, Shuai Q, Li Z, Le XC.

J Environ Sci (China). 2017 Nov;61:118-121. doi: 10.1016/j.jes.2017.11.010. No abstract available.


DNAzyme-Mediated Assays for Amplified Detection of Nucleic Acids and Proteins.

Peng H, Newbigging AM, Wang Z, Tao J, Deng W, Le XC, Zhang H.

Anal Chem. 2018 Jan 2;90(1):190-207. doi: 10.1021/acs.analchem.7b04926. Epub 2017 Dec 13. No abstract available.


Effect of copper on the translocation and transformation of polychlorinated biphenyls in rice.

Pan L, Sun J, Le XC, Zhu L.

Chemosphere. 2018 Feb;193:514-520. doi: 10.1016/j.chemosphere.2017.11.054. Epub 2017 Nov 13.


A Neurodynamic Approach to Distributed Optimization With Globally Coupled Constraints.

Le X, Chen S, Yan Z, Xi J.

IEEE Trans Cybern. 2018 Nov;48(11):3149-3158. doi: 10.1109/TCYB.2017.2760908. Epub 2017 Oct 18.


A systematic and genome-wide correlation meta-analysis of PD-L1 expression and targetable NSCLC driver genes.

Li J, Chen Y, Shi X, Le X, Feng F, Chen J, Zhou C, Chen Y, Wen S, Zeng H, Chen AM, Zhang Y.

J Thorac Dis. 2017 Aug;9(8):2560-2571. doi: 10.21037/jtd.2017.07.117.


Establishment and characterization of arsenic trioxide resistant KB/ATO cells.

Zhang YK, Dai C, Yuan CG, Wu HC, Xiao Z, Lei ZN, Yang DH, Le XC, Fu L, Chen ZS.

Acta Pharm Sin B. 2017 Sep;7(5):564-570. doi: 10.1016/j.apsb.2017.04.001. Epub 2017 Apr 28.


Metabolomics analysis of TiO2 nanoparticles induced toxicological effects on rice (Oryza sativa L.).

Wu B, Zhu L, Le XC.

Environ Pollut. 2017 Nov;230:302-310. doi: 10.1016/j.envpol.2017.06.062. Epub 2017 Jun 28.


Cases of ALK-Rearranged Lung Cancer with 5-Year Progression-Free Survival with Crizotinib as Initial Precision Therapy.

Rangachari D, Le X, Shea M, Huberman MS, VanderLaan PA, Kobayashi SS, Costa DB.

J Thorac Oncol. 2017 Nov;12(11):e175-e177. doi: 10.1016/j.jtho.2017.06.002. Epub 2017 Jun 10. No abstract available.


Novel insights of microRNAs in the development of systemic lupus erythematosus.

Le X, Yu X, Shen N.

Curr Opin Rheumatol. 2017 Sep;29(5):450-457. doi: 10.1097/BOR.0000000000000420. Review.


Methylated Phenylarsenical Metabolites Discovered in Chicken Liver.

Peng H, Hu B, Liu Q, Li J, Li XF, Zhang H, Le XC.

Angew Chem Int Ed Engl. 2017 Jun 6;56(24):6773-6777. doi: 10.1002/anie.201700736. Epub 2017 May 4.


Stretchable supramolecular hydrogels with triple shape memory effect.

Le X, Lu W, Zheng J, Tong D, Zhao N, Ma C, Xiao H, Zhang J, Huang Y, Chen T.

Chem Sci. 2016 Nov 1;7(11):6715-6720. doi: 10.1039/c6sc02354a. Epub 2016 Jul 7.


Development of a Simple Noninvasive Model to Predict Significant Fibrosis in Patients with Chronic Hepatitis B: Combination of Ultrasound Elastography, Serum Biomarkers, and Individual Characteristics.

Chen X, Wen H, Zhang X, Dong C, Lin H, Guo Y, Shan L, Yao S, Yang M, Le X, Liu Y.

Clin Transl Gastroenterol. 2017 Apr 6;8(4):e84. doi: 10.1038/ctg.2017.11.

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